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The map label for this gene is efp_1

Identifier: 15835719

GI number: 15835719

Start: 220841

End: 221398

Strand: Reverse

Name: efp_1

Synonym: CPj0184

Alternate gene names: 15835719

Gene position: 221398-220841 (Counterclockwise)

Preceding gene: 15835720

Following gene: 15835718

Centisome position: 18.05

GC content: 37.28

Gene sequence:

>558_bases
ATGGTGTTAAGTAGCCAATTATCCGTAGGGATGTTTATTTCTACAAAGGACGGTCTTTATAAAGTAACCTCAGTGTCTAA
GGTGGCAGGGCCCAAAGGCGAATCCTTCATTAAAGTCGCTTTGCAGGCTGCGGATTCTGATGTTGTTATTGAGAGAAATT
TCAAAGCAACTCAAGAGGTAAAAGAGGCTCAATTTGAAACCCGCACTTTAGAATATTTATATCTTGAAGATGAAAGTTAT
CTTTTTTTAGATTTAGGAAATTATGAAAAGTTATTCATTCCACAAGAAATCATGAAGGATAACTTTTTGTTTTTAAAGGC
AGGTGTGACTGTCTCTGCAATGGTCTATGACAATGTGGTTTTTTCTGTAGAGCTGCCTCATTTTCTAGAGCTTATGGTAT
CAAAAACAGACTTTCCTGGAGATTCTCTCTCTCTTTCCGGAGGAGTTAAGAAAGCTTTGCTGGAAACAGGAATTGAAGTT
ATGGTCCCACCTTTTGTAGAAATTGGTGATGTTATAAAAATAGATACGCGGACTTGTGAGTATATTCAACGCGTCTAA

Upstream 100 bases:

>100_bases
CGAGATGCAGGAGCAGATATTTTAGTCACAGCTTCTTACTTATTCGAAGCAGATTCATTAGCAATGGAAGATAAAATTTT
GTTGCTGCGAGGAGAAAATT

Downstream 100 bases:

>100_bases
TTTCAATTAAAGAAGACTTGGTATGGACTTAAAACAAATAGAAAAGCTCATGATTGCTATGGGACGCAATGGTATGAAGC
GTTTTGCTATAAAACGTGAA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 1

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MVLSSQLSVGMFISTKDGLYKVTSVSKVAGPKGESFIKVALQAADSDVVIERNFKATQEVKEAQFETRTLEYLYLEDESY
LFLDLGNYEKLFIPQEIMKDNFLFLKAGVTVSAMVYDNVVFSVELPHFLELMVSKTDFPGDSLSLSGGVKKALLETGIEV
MVPPFVEIGDVIKIDTRTCEYIQRV

Sequences:

>Translated_185_residues
MVLSSQLSVGMFISTKDGLYKVTSVSKVAGPKGESFIKVALQAADSDVVIERNFKATQEVKEAQFETRTLEYLYLEDESY
LFLDLGNYEKLFIPQEIMKDNFLFLKAGVTVSAMVYDNVVFSVELPHFLELMVSKTDFPGDSLSLSGGVKKALLETGIEV
MVPPFVEIGDVIKIDTRTCEYIQRV
>Mature_185_residues
MVLSSQLSVGMFISTKDGLYKVTSVSKVAGPKGESFIKVALQAADSDVVIERNFKATQEVKEAQFETRTLEYLYLEDESY
LFLDLGNYEKLFIPQEIMKDNFLFLKAGVTVSAMVYDNVVFSVELPHFLELMVSKTDFPGDSLSLSGGVKKALLETGIEV
MVPPFVEIGDVIKIDTRTCEYIQRV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=8e-20,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP1_CHLPN (Q9Z900)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   G72110
- PIR:   H86513
- RefSeq:   NP_224393.1
- RefSeq:   NP_300243.1
- RefSeq:   NP_445127.1
- RefSeq:   NP_876463.1
- ProteinModelPortal:   Q9Z900
- SMR:   Q9Z900
- PHCI-2DPAGE:   Q9Z900
- GeneID:   1466870
- GeneID:   895189
- GeneID:   918980
- GeneID:   962836
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0584
- KEGG:   cpn:CPn0184
- KEGG:   cpt:CpB0187
- TIGR:   CP_0584
- HOGENOM:   HBG303311
- OMA:   LELMVSK
- ProtClustDB:   PRK12426
- BioCyc:   CPNE115711:CP_0584-MONOMER
- BioCyc:   CPNE115713:CPN0184-MONOMER
- BioCyc:   CPNE138677:CPJ0184-MONOMER
- BioCyc:   CPNE182082:CPB0187-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20673; Mature: 20673

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSSQLSVGMFISTKDGLYKVTSVSKVAGPKGESFIKVALQAADSDVVIERNFKATQEV
CEECCCCCEEEEEECCCCEEEEEEHHHHCCCCCCCEEEEEEECCCCCEEEECCCCHHHHH
KEAQFETRTLEYLYLEDESYLFLDLGNYEKLFIPQEIMKDNFLFLKAGVTVSAMVYDNVV
HHHHHHHEEEEEEEEECCCEEEEECCCCCEEECCHHHHCCCEEEEEECCEEEEEEECCEE
FSVELPHFLELMVSKTDFPGDSLSLSGGVKKALLETGIEVMVPPFVEIGDVIKIDTRTCE
EEEECHHHHHHHHHCCCCCCCCEEECCCHHHHHHHCCCEEEECCCCCCCCEEEECCHHHH
YIQRV
HHHCC
>Mature Secondary Structure
MVLSSQLSVGMFISTKDGLYKVTSVSKVAGPKGESFIKVALQAADSDVVIERNFKATQEV
CEECCCCCEEEEEECCCCEEEEEEHHHHCCCCCCCEEEEEEECCCCCEEEECCCCHHHHH
KEAQFETRTLEYLYLEDESYLFLDLGNYEKLFIPQEIMKDNFLFLKAGVTVSAMVYDNVV
HHHHHHHEEEEEEEEECCCEEEEECCCCCEEECCHHHHCCCEEEEEECCEEEEEEECCEE
FSVELPHFLELMVSKTDFPGDSLSLSGGVKKALLETGIEVMVPPFVEIGDVIKIDTRTCE
EEEECHHHHHHHHHCCCCCCCCEEECCCHHHHHHHCCCEEEECCCCCCCCEEEECCHHHH
YIQRV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362