| Definition | Borrelia burgdorferi B31 chromosome, complete genome. |
|---|---|
| Accession | NC_001318 |
| Length | 910,724 |
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The map label for this gene is mrcA [H]
Identifier: 15595077
GI number: 15595077
Start: 771570
End: 774368
Strand: Reverse
Name: mrcA [H]
Synonym: BB0732
Alternate gene names: 15595077
Gene position: 774368-771570 (Counterclockwise)
Preceding gene: 15595079
Following gene: 15595076
Centisome position: 85.03
GC content: 31.62
Gene sequence:
>2799_bases ATGAAATTGAATAGCCCTAATTTGAAAAAAATAAATACGCATAAGCTGCTTATATATTTAACATATTTCGCAGTTAGCTT TTCTATTATCACACTCTCATTAGCAGTATCTAAGACTATAAACATACAAAAAGATAAAAATTTCGGATATGTAAATCCAG CAGTTCCTTCAAGACTTTTAGATATTAATGGAAAACAAATAACTCAATTTATATCTGATGAGAACAGAGAATTAATGCCT TTGAGAAAAATGCCTGACAATCTAATTAATACGCTTTTGATACGGGAAGATATTGGTTTTTTTTCTCATCGAGGTTTTTC CTTGATAGGAATATTTAGAGCCGCATTTAATATTGTTCTTGGCAGATATTTTTCAGGCGGCAGCACATTAACCCAACAAC TTGCAAAGCTTCTCTACACAAATCAAGCAAGAAGATCTATTTTGAGAAAATTACATGAAATATGGTGGGCAATTCAACTT GAAAAAAAACTCTCAAAATACGAAATACTAGAGAAGTACCTTAATAAAGTTTATTTTGGAAACGGAAACTATGGAATAGT TGCAGCATCAAAATTCTTTTTTGGCAAAAGTGTAAATAAAATCAATACAGCAGAATCAGTAATGATGATAATCCAGCTTC CAAATGCAAAACTTTATTCACCTCTTTACAATCCAGAATTTTCAAAAAAAATACAACGTGCAGTTTTAAACCAAGTTGTA TCAAATGGAATAGTCAAGGCTGAAATTGCTGAAAAAGAATTTAATGAATACTGGCAAAATTATGATTGGACTAGAATGGC TGACACATCTGCAATTTCAAACAAAAAAGACCAAGCTCCTTATTTCTCTGAATATATAAGGCAAAAAATACTAAAATATT TACCAGATGGCGCAAACATATATAAAGATGGGTACTCAATATATTCAACCCTTGATCTTGAAGCACAAAAATATGCAGAT AAAGTTACAAACGACATGATTAATAAAGCAAGAACAATGCACAATTTAAATAGATCATCTGAAACAATAATCATTAATTC AGAAATTGTCCCTGTAGTAGATGCGATATCAGATTTATTGGGAATTAAAAATTTAAGAATAAATGGAAGACAATATAAAA AACTGAGAAAAAGAAAATTTTACGAAGACAATATTGATCTAATTGCAAGTTTTGGAGCTATACTTGGAATTGATAAAATA GATAAGGCGACAAAAGAATATATTATCAAAAATAAATTAACACCGAAACTTATTGCACAGCCTGAAGGAGCAATGATAGC AATAGATACAACAAGTGGAGCAATAAGAGCCATGGTTGGGGGAAGTGGACACACTAAAGACAATGAATTTAATCGAGCCA CACAAGCAAAAGTTCAGCCTGGAAGTGCATTCAAAGCATTATATTTTGCAGCCGCAATTGATCTAAAAAAAATAACAGCT GCGACAATGTTTTCAGACTCTCCAGTAGCATTTCTAAATAAAAATGGAGAAGTTTATGCTCCGGGAAATTATGGCGGCAA ATGGAGAGGCAACGTTTTAACGCGCCAAGCATTAGCTTTGTCCTTAAATATTCCGGCATTAAGAATATTAGACCGGCTAG GCTTTGACTCTGCAATTAGCTACTCCTCAAAACTACTAGGAATAACAGATCCAAAAGAAATAGAAAAAACGTTTCCAAAA GTTTATCCACTAGCGCTAGGTGTAATATCAGTTTCTCCAATCCAAATGGCAAGAGCCTTTGCAATTTTAGGAAATAGTGG TAGCGAAATCGAACCTTATGGGATAAGATACATTGAAGACAGAGCTGGAAGAATAATAACAAATGAAGAAGCAAGCATAT TGGCTAAAATAAAAAACAAAGAACACCAAACTCAAATAGTATCTCCTCAAACCGCTTACATAATCACAGATATGATGAAA TCAACAATTCAATACGGAACCCTAGCAAATCAAAGATATACAAATCTCAAAAATTTTAAATCAGACATTGCTGGAAAATC GGGAACAACACAAAATTGGGCAGACGGATGGGCAATAGGATACTCTCCTTATATAACAACAGCATTTTGGGTTGGATTTG ACAAAAAAGGATATTCACTGGGAATATCTGGAACAGGAACAGGATTGGCAGGGCCTAGTTGGGGAGAATTTATGGCAGAA TATCACAAAAACTTACCCAAAAAAGTTTTTGTAAAACCTGCAGGAATAATTAGCATCCCCGTACAAGCAGAAACGGGTCT ACTACCGGAAGAAATTGCTGATGAAAAAATAATAAATGAACTATTTATTTCCGGCACCCAGCCAGTTGAAAAATCAAAAT ATTATGAAAATAAACAAGAATTTAAAAATACAATAGAATTTAACATATATGGAATTGATGAGATTAATAATAACGATGAA ATAAATTTTGACACTCCTGAATTTGAATATCTTGATAATAATCTTGAAAGCTTTAATAACAATAGTAATAATGATAATAA TCTTGAAAGCTTTAACAATAATAACAATGATCTTGAAAGCATTAATGATAATGAAGAAAATAAAAATGAAGATGAAATAG AAATGAACATTGAAGAACCCTTAAATGAAATAGAAAATAAAAATCCACAACAAGATCTAGTTAATAACAATAATAACCAG GAAATGCTTATTGAAAACACCAAAGAAATTAAAGACGAAGTCATTGTTAATGAAACAAACATAGAAACACAAAGCACAAA AGAATTAAATTCAAACAACAATGAAAATGAAAAAATTAACAACAAAGACGTCAACGGAGAAGATATCCAATTGGATTAA
Upstream 100 bases:
>100_bases GTTTACATAGTGTAAAATTATAACAATAATTTTACACTATAACAATCAACCCATAACATTATTAATTCTTATGCACTTAT AGTATACTTTAGTAAAAAGT
Downstream 100 bases:
>100_bases AACAATATGTTAATAGATATCGATCAAATAAAAATAAAAAAAAGAATTAGAAAAAATATAGGAGACATTGAAACTCTTAA AAACAGTATTATAAAACATG
Product: penicillin-binding protein
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 932; Mature: 932
Protein sequence:
>932_residues MKLNSPNLKKINTHKLLIYLTYFAVSFSIITLSLAVSKTINIQKDKNFGYVNPAVPSRLLDINGKQITQFISDENRELMP LRKMPDNLINTLLIREDIGFFSHRGFSLIGIFRAAFNIVLGRYFSGGSTLTQQLAKLLYTNQARRSILRKLHEIWWAIQL EKKLSKYEILEKYLNKVYFGNGNYGIVAASKFFFGKSVNKINTAESVMMIIQLPNAKLYSPLYNPEFSKKIQRAVLNQVV SNGIVKAEIAEKEFNEYWQNYDWTRMADTSAISNKKDQAPYFSEYIRQKILKYLPDGANIYKDGYSIYSTLDLEAQKYAD KVTNDMINKARTMHNLNRSSETIIINSEIVPVVDAISDLLGIKNLRINGRQYKKLRKRKFYEDNIDLIASFGAILGIDKI DKATKEYIIKNKLTPKLIAQPEGAMIAIDTTSGAIRAMVGGSGHTKDNEFNRATQAKVQPGSAFKALYFAAAIDLKKITA ATMFSDSPVAFLNKNGEVYAPGNYGGKWRGNVLTRQALALSLNIPALRILDRLGFDSAISYSSKLLGITDPKEIEKTFPK VYPLALGVISVSPIQMARAFAILGNSGSEIEPYGIRYIEDRAGRIITNEEASILAKIKNKEHQTQIVSPQTAYIITDMMK STIQYGTLANQRYTNLKNFKSDIAGKSGTTQNWADGWAIGYSPYITTAFWVGFDKKGYSLGISGTGTGLAGPSWGEFMAE YHKNLPKKVFVKPAGIISIPVQAETGLLPEEIADEKIINELFISGTQPVEKSKYYENKQEFKNTIEFNIYGIDEINNNDE INFDTPEFEYLDNNLESFNNNSNNDNNLESFNNNNNDLESINDNEENKNEDEIEMNIEEPLNEIENKNPQQDLVNNNNNQ EMLIENTKEIKDEVIVNETNIETQSTKELNSNNNENEKINNKDVNGEDIQLD
Sequences:
>Translated_932_residues MKLNSPNLKKINTHKLLIYLTYFAVSFSIITLSLAVSKTINIQKDKNFGYVNPAVPSRLLDINGKQITQFISDENRELMP LRKMPDNLINTLLIREDIGFFSHRGFSLIGIFRAAFNIVLGRYFSGGSTLTQQLAKLLYTNQARRSILRKLHEIWWAIQL EKKLSKYEILEKYLNKVYFGNGNYGIVAASKFFFGKSVNKINTAESVMMIIQLPNAKLYSPLYNPEFSKKIQRAVLNQVV SNGIVKAEIAEKEFNEYWQNYDWTRMADTSAISNKKDQAPYFSEYIRQKILKYLPDGANIYKDGYSIYSTLDLEAQKYAD KVTNDMINKARTMHNLNRSSETIIINSEIVPVVDAISDLLGIKNLRINGRQYKKLRKRKFYEDNIDLIASFGAILGIDKI DKATKEYIIKNKLTPKLIAQPEGAMIAIDTTSGAIRAMVGGSGHTKDNEFNRATQAKVQPGSAFKALYFAAAIDLKKITA ATMFSDSPVAFLNKNGEVYAPGNYGGKWRGNVLTRQALALSLNIPALRILDRLGFDSAISYSSKLLGITDPKEIEKTFPK VYPLALGVISVSPIQMARAFAILGNSGSEIEPYGIRYIEDRAGRIITNEEASILAKIKNKEHQTQIVSPQTAYIITDMMK STIQYGTLANQRYTNLKNFKSDIAGKSGTTQNWADGWAIGYSPYITTAFWVGFDKKGYSLGISGTGTGLAGPSWGEFMAE YHKNLPKKVFVKPAGIISIPVQAETGLLPEEIADEKIINELFISGTQPVEKSKYYENKQEFKNTIEFNIYGIDEINNNDE INFDTPEFEYLDNNLESFNNNSNNDNNLESFNNNNNDLESINDNEENKNEDEIEMNIEEPLNEIENKNPQQDLVNNNNNQ EMLIENTKEIKDEVIVNETNIETQSTKELNSNNNENEKINNKDVNGEDIQLD >Mature_932_residues MKLNSPNLKKINTHKLLIYLTYFAVSFSIITLSLAVSKTINIQKDKNFGYVNPAVPSRLLDINGKQITQFISDENRELMP LRKMPDNLINTLLIREDIGFFSHRGFSLIGIFRAAFNIVLGRYFSGGSTLTQQLAKLLYTNQARRSILRKLHEIWWAIQL EKKLSKYEILEKYLNKVYFGNGNYGIVAASKFFFGKSVNKINTAESVMMIIQLPNAKLYSPLYNPEFSKKIQRAVLNQVV SNGIVKAEIAEKEFNEYWQNYDWTRMADTSAISNKKDQAPYFSEYIRQKILKYLPDGANIYKDGYSIYSTLDLEAQKYAD KVTNDMINKARTMHNLNRSSETIIINSEIVPVVDAISDLLGIKNLRINGRQYKKLRKRKFYEDNIDLIASFGAILGIDKI DKATKEYIIKNKLTPKLIAQPEGAMIAIDTTSGAIRAMVGGSGHTKDNEFNRATQAKVQPGSAFKALYFAAAIDLKKITA ATMFSDSPVAFLNKNGEVYAPGNYGGKWRGNVLTRQALALSLNIPALRILDRLGFDSAISYSSKLLGITDPKEIEKTFPK VYPLALGVISVSPIQMARAFAILGNSGSEIEPYGIRYIEDRAGRIITNEEASILAKIKNKEHQTQIVSPQTAYIITDMMK STIQYGTLANQRYTNLKNFKSDIAGKSGTTQNWADGWAIGYSPYITTAFWVGFDKKGYSLGISGTGTGLAGPSWGEFMAE YHKNLPKKVFVKPAGIISIPVQAETGLLPEEIADEKIINELFISGTQPVEKSKYYENKQEFKNTIEFNIYGIDEINNNDE INFDTPEFEYLDNNLESFNNNSNNDNNLESFNNNNNDLESINDNEENKNEDEIEMNIEEPLNEIENKNPQQDLVNNNNNQ EMLIENTKEIKDEVIVNETNIETQSTKELNSNNNENEKINNKDVNGEDIQLD
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=826, Percent_Identity=26.9975786924939, Blast_Score=254, Evalue=2e-68, Organism=Escherichia coli, GI1786343, Length=321, Percent_Identity=28.3489096573209, Blast_Score=111, Evalue=2e-25, Organism=Escherichia coli, GI1788867, Length=170, Percent_Identity=35.2941176470588, Blast_Score=91, Evalue=4e-19, Organism=Escherichia coli, GI1789601, Length=130, Percent_Identity=36.1538461538462, Blast_Score=64, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 105256; Mature: 105256
Theoretical pI: Translated: 6.68; Mature: 6.68
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLNSPNLKKINTHKLLIYLTYFAVSFSIITLSLAVSKTINIQKDKNFGYVNPAVPSRLL CCCCCCCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCEE DINGKQITQFISDENRELMPLRKMPDNLINTLLIREDIGFFSHRGFSLIGIFRAAFNIVL CCCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHH GRYFSGGSTLTQQLAKLLYTNQARRSILRKLHEIWWAIQLEKKLSKYEILEKYLNKVYFG HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC NGNYGIVAASKFFFGKSVNKINTAESVMMIIQLPNAKLYSPLYNPEFSKKIQRAVLNQVV CCCEEEEEEEHHHHCCCCCCCCCHHHEEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHH SNGIVKAEIAEKEFNEYWQNYDWTRMADTSAISNKKDQAPYFSEYIRQKILKYLPDGANI HCCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC YKDGYSIYSTLDLEAQKYADKVTNDMINKARTMHNLNRSSETIIINSEIVPVVDAISDLL CCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHH GIKNLRINGRQYKKLRKRKFYEDNIDLIASFGAILGIDKIDKATKEYIIKNKLTPKLIAQ CCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHEEC PEGAMIAIDTTSGAIRAMVGGSGHTKDNEFNRATQAKVQPGSAFKALYFAAAIDLKKITA CCCCEEEEECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHH ATMFSDSPVAFLNKNGEVYAPGNYGGKWRGNVLTRQALALSLNIPALRILDRLGFDSAIS HHEECCCCEEEECCCCCEEECCCCCCCCCCCHHHHEEEEEEECCHHHHHHHHHCCCHHHC YSSKLLGITDPKEIEKTFPKVYPLALGVISVSPIQMARAFAILGNSGSEIEPYGIRYIED CCCCEECCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCCCEEEEC RAGRIITNEEASILAKIKNKEHQTQIVSPQTAYIITDMMKSTIQYGTLANQRYTNLKNFK CCCCEEECCHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH SDIAGKSGTTQNWADGWAIGYSPYITTAFWVGFDKKGYSLGISGTGTGLAGPSWGEFMAE HHHCCCCCCCCCCCCCEEECCCHHHHEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHH YHKNLPKKVFVKPAGIISIPVQAETGLLPEEIADEKIINELFISGTQPVEKSKYYENKQE HHHCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHH FKNTIEFNIYGIDEINNNDEINFDTPEFEYLDNNLESFNNNSNNDNNLESFNNNNNDLES HCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHCCHHHCCCCCCCCCCCHHCCCCCCCCCC INDNEENKNEDEIEMNIEEPLNEIENKNPQQDLVNNNNNQEMLIENTKEIKDEVIVNETN CCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHCCCCCCEEEECCHHHHHHHHEEECCC IETQSTKELNSNNNENEKINNKDVNGEDIQLD CCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEC >Mature Secondary Structure MKLNSPNLKKINTHKLLIYLTYFAVSFSIITLSLAVSKTINIQKDKNFGYVNPAVPSRLL CCCCCCCCCEECCCEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCEE DINGKQITQFISDENRELMPLRKMPDNLINTLLIREDIGFFSHRGFSLIGIFRAAFNIVL CCCHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHH GRYFSGGSTLTQQLAKLLYTNQARRSILRKLHEIWWAIQLEKKLSKYEILEKYLNKVYFG HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC NGNYGIVAASKFFFGKSVNKINTAESVMMIIQLPNAKLYSPLYNPEFSKKIQRAVLNQVV CCCEEEEEEEHHHHCCCCCCCCCHHHEEEEEECCCCHHCCCCCCCHHHHHHHHHHHHHHH SNGIVKAEIAEKEFNEYWQNYDWTRMADTSAISNKKDQAPYFSEYIRQKILKYLPDGANI HCCCEEEHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCC YKDGYSIYSTLDLEAQKYADKVTNDMINKARTMHNLNRSSETIIINSEIVPVVDAISDLL CCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHH GIKNLRINGRQYKKLRKRKFYEDNIDLIASFGAILGIDKIDKATKEYIIKNKLTPKLIAQ CCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHEEC PEGAMIAIDTTSGAIRAMVGGSGHTKDNEFNRATQAKVQPGSAFKALYFAAAIDLKKITA CCCCEEEEECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHH ATMFSDSPVAFLNKNGEVYAPGNYGGKWRGNVLTRQALALSLNIPALRILDRLGFDSAIS HHEECCCCEEEECCCCCEEECCCCCCCCCCCHHHHEEEEEEECCHHHHHHHHHCCCHHHC YSSKLLGITDPKEIEKTFPKVYPLALGVISVSPIQMARAFAILGNSGSEIEPYGIRYIED CCCCEECCCCHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCCCEEEEC RAGRIITNEEASILAKIKNKEHQTQIVSPQTAYIITDMMKSTIQYGTLANQRYTNLKNFK CCCCEEECCHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH SDIAGKSGTTQNWADGWAIGYSPYITTAFWVGFDKKGYSLGISGTGTGLAGPSWGEFMAE HHHCCCCCCCCCCCCCEEECCCHHHHEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHH YHKNLPKKVFVKPAGIISIPVQAETGLLPEEIADEKIINELFISGTQPVEKSKYYENKQE HHHCCCCEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHH FKNTIEFNIYGIDEINNNDEINFDTPEFEYLDNNLESFNNNSNNDNNLESFNNNNNDLES HCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHCCHHHCCCCCCCCCCCHHCCCCCCCCCC INDNEENKNEDEIEMNIEEPLNEIENKNPQQDLVNNNNNQEMLIENTKEIKDEVIVNETN CCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHCCCCCCEEEECCHHHHHHHHEEECCC IETQSTKELNSNNNENEKINNKDVNGEDIQLD CCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA