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The map label for this gene is ywlC [H]

Identifier: 15595079

GI number: 15595079

Start: 775666

End: 776679

Strand: Reverse

Name: ywlC [H]

Synonym: BB0734

Alternate gene names: 15595079

Gene position: 776679-775666 (Counterclockwise)

Preceding gene: 15595084

Following gene: 15595077

Centisome position: 85.28

GC content: 29.68

Gene sequence:

>1014_bases
ATGATATCAACAGAAATAATTAGCAGCAGCCAAATACAAAAAGCAGCAAAACTTATCAAAATGGGAGAACTTGTAGTATT
CCCAACAGAAACAGTTTACGGAATTGGCGCAAATGCTTACAATGAAGATGCTGTAAAAATGATTTTTTTAGTAAAAAAAA
GGCCCATCAACAATCCTTTAATAGTACATGTTGATACGGTAAAAAAAATAAAAGAATTATCAGAATATATTCCCAAAAGT
GCCCTCATGCTAATCAAAAAATTTAGTCCAGGCCCTTTAACTTATGTTCTTAAAAAATCAATAAAAATATCTAGATTTGT
AAGTGGAAACCTAGACACAGTGGCAATAAGAATTCCTGCAAATAAAACAGCTTTAAGCCTAATAAAAGCATCTAAAGTCC
CCATAGTAGCACCGTCTGCAAACATATCAAAAAGACCAAGCTCAACAAATTTCGAAATGGCCTTAAAAGAATTAAATGGA
CTTGTAAGAGGAATAATAAAACCGGAAGAGAACAAAGACTTTAATATTGGAATCGAATCAACTGTGGTTGGGTTTGACCT
AAAAGATAACGTACTGATATTAAGACCAGGCGCAATAACAAAAAAAATGATAGAAAATGAACTTCAAGGAAAATATACAG
TAAATTACGCAGAAACAAAAATGGAACTAGAAAAATCACCTGGAAACATAATTGAACATTATAAGCCAAAAATTCCCGTT
TATTTATTTAAAAGTCAAGATAACATAAGAAGATACTTAAACAAAGATACGAAAATACTTATCACAAAAGCTACTCTAAA
ATCCTATTTATTCAATTTTTTTTGGAATAAAAAAAATATTACAGTATTTAACACTCTTGAAGAATATGCACAAAACCTTT
ACAAAGAGTTGGTAAATTCTGAAAACAACTACAAACAAATACTTAGCGAATTCTTAAAAGACGAAGAACTTGGACATTCA
ATAAACAATAGAATCAAAAAAGCTAGTTCAAATAGATTCATTAACAAAAAATGA

Upstream 100 bases:

>100_bases
TTATTATAATATAAAAACATATTTCAATAAACAATTAAGCTTGCAAATTGCTTATTTACATTTTTTTTGATTTAATTATA
AAAAGAAAAAAGTCTAAAAA

Downstream 100 bases:

>100_bases
CGCTAAATTGTTATTTAAAATAATTCAAAAAGCATAAATATTCATTAATAAAATAATGCTAAAGCTAAAAGCAAAAGTCT
AAAACACGCCACACCTCTCC

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MISTEIISSSQIQKAAKLIKMGELVVFPTETVYGIGANAYNEDAVKMIFLVKKRPINNPLIVHVDTVKKIKELSEYIPKS
ALMLIKKFSPGPLTYVLKKSIKISRFVSGNLDTVAIRIPANKTALSLIKASKVPIVAPSANISKRPSSTNFEMALKELNG
LVRGIIKPEENKDFNIGIESTVVGFDLKDNVLILRPGAITKKMIENELQGKYTVNYAETKMELEKSPGNIIEHYKPKIPV
YLFKSQDNIRRYLNKDTKILITKATLKSYLFNFFWNKKNITVFNTLEEYAQNLYKELVNSENNYKQILSEFLKDEELGHS
INNRIKKASSNRFINKK

Sequences:

>Translated_337_residues
MISTEIISSSQIQKAAKLIKMGELVVFPTETVYGIGANAYNEDAVKMIFLVKKRPINNPLIVHVDTVKKIKELSEYIPKS
ALMLIKKFSPGPLTYVLKKSIKISRFVSGNLDTVAIRIPANKTALSLIKASKVPIVAPSANISKRPSSTNFEMALKELNG
LVRGIIKPEENKDFNIGIESTVVGFDLKDNVLILRPGAITKKMIENELQGKYTVNYAETKMELEKSPGNIIEHYKPKIPV
YLFKSQDNIRRYLNKDTKILITKATLKSYLFNFFWNKKNITVFNTLEEYAQNLYKELVNSENNYKQILSEFLKDEELGHS
INNRIKKASSNRFINKK
>Mature_337_residues
MISTEIISSSQIQKAAKLIKMGELVVFPTETVYGIGANAYNEDAVKMIFLVKKRPINNPLIVHVDTVKKIKELSEYIPKS
ALMLIKKFSPGPLTYVLKKSIKISRFVSGNLDTVAIRIPANKTALSLIKASKVPIVAPSANISKRPSSTNFEMALKELNG
LVRGIIKPEENKDFNIGIESTVVGFDLKDNVLILRPGAITKKMIENELQGKYTVNYAETKMELEKSPGNIIEHYKPKIPV
YLFKSQDNIRRYLNKDTKILITKATLKSYLFNFFWNKKNITVFNTLEEYAQNLYKELVNSENNYKQILSEFLKDEELGHS
INNRIKKASSNRFINKK

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=183, Percent_Identity=26.775956284153, Blast_Score=79, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321269, Length=386, Percent_Identity=29.5336787564767, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI78707274, Length=141, Percent_Identity=29.0780141843972, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 38280; Mature: 38280

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTEIISSSQIQKAAKLIKMGELVVFPTETVYGIGANAYNEDAVKMIFLVKKRPINNPL
CCCCHHCCHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCHHHEEEEEEECCCCCCCE
IVHVDTVKKIKELSEYIPKSALMLIKKFSPGPLTYVLKKSIKISRFVSGNLDTVAIRIPA
EEEEHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHCCEEEEEECCCCCEEEEEECC
NKTALSLIKASKVPIVAPSANISKRPSSTNFEMALKELNGLVRGIIKPEENKDFNIGIES
CHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
TVVGFDLKDNVLILRPGAITKKMIENELQGKYTVNYAETKMELEKSPGNIIEHYKPKIPV
EEEEEECCCCEEEECCCHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHCCCCCCE
YLFKSQDNIRRYLNKDTKILITKATLKSYLFNFFWNKKNITVFNTLEEYAQNLYKELVNS
EEECCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCC
ENNYKQILSEFLKDEELGHSINNRIKKASSNRFINKK
CCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MISTEIISSSQIQKAAKLIKMGELVVFPTETVYGIGANAYNEDAVKMIFLVKKRPINNPL
CCCCHHCCHHHHHHHHHHHHHCCEEEEECCEEEECCCCCCCCHHHEEEEEEECCCCCCCE
IVHVDTVKKIKELSEYIPKSALMLIKKFSPGPLTYVLKKSIKISRFVSGNLDTVAIRIPA
EEEEHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHCCEEEEEECCCCCEEEEEECC
NKTALSLIKASKVPIVAPSANISKRPSSTNFEMALKELNGLVRGIIKPEENKDFNIGIES
CHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
TVVGFDLKDNVLILRPGAITKKMIENELQGKYTVNYAETKMELEKSPGNIIEHYKPKIPV
EEEEEECCCCEEEECCCHHHHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHCCCCCCE
YLFKSQDNIRRYLNKDTKILITKATLKSYLFNFFWNKKNITVFNTLEEYAQNLYKELVNS
EEECCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCC
ENNYKQILSEFLKDEELGHSINNRIKKASSNRFINKK
CCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]