Click here to switch to the map view.

The map label for this gene is 15594849

Identifier: 15594849

GI number: 15594849

Start: 509314

End: 510846

Strand: Direct

Name: 15594849

Synonym: BB0504

Alternate gene names: NA

Gene position: 509314-510846 (Clockwise)

Preceding gene: 15594848

Following gene: 15594850

Centisome position: 55.92

GC content: 33.72

Gene sequence:

>1533_bases
ATGATATATATTATTTTTTCTTCTATTTTTGCTGGCTTTATATTAGGATTTTTAGTAAGAGTTTTTTTAGGTAGATTGTC
TTTATTAGATTTAGAAAAAAATCTGAAAAAAGTAAGAGTAGAATCACAATTAGAGATAGAAAATGAAAGAAGGCAAATTA
TTGCTAATGCAAAATCTCAAATGCTTAAAGAAAAAAACCAGCAAGATAGGGATATAAGAGATCGGAAAAATGAGATTGTT
AATTTAGAAAAAAGATTATTACAAAGAGAAGAAACTTTAGATAAGAGAATATCTGCTCTTGACAAACAGCAGTCTAGAGT
TGATTTTAAAATTAAAGAATTTGAACAAAAAGAAAAAGTAATAAGAGAAAAAGAGGCCGATCTTGTTAAAAGATTGGAAA
ATATTTCTGGTCTTACAAGAGAAGATGCAAGAAAAATTGTAATTGAAAAAGTTGAGCATGAGTCCAAAAGAGATGCTCAA
GTTATTATCAATAAAAGTGAGCAGGAAGCACAGCTATTAGCAGATAAGGTTGCAAAAGATATTTTAGTATCTACTATGCA
GCGTATTGTTACGGAGGTGAGTTCTGAGTTTACAGTGGCTTCTGTTGAGCTACCTAATGATGAGATGAAAGGTAGGATTA
TAGGTAAAGAAGGGCGCAATATTAGGGCTCTTGAGACTTTAATAGGAGCAGATATCATTATTGATGATACGCCTGAAGCT
GTTGTTATATCTTGCTTTGATCCAATAAGAAAAGAGCTTGCCAAGAGGACTTTAGAAAGGCTTGTTACAGATGGCAGAAT
TCATCCTGCTAGGATTGAAGAAGTTGTGTATAATGTTACCAATGAGATAAATAGCATTATTCAAGAAGAGGGTGAGAAGG
TGGTTTTTGACCTTAATATACATGGGCTTGATAAGAGACTTATTAGGGGGTTGGGAAGGCTTTACTTTAGAAGCAGTTAT
GGTCAAAATGTTTTAAGCCACTCTAAAGAAACGGCTATAATAGGAGAAATTTTGGCTAAAGAGATGAAATTAGATCCTGT
TGTAGTAAAAAGAGCATGCCTTTTGCATGATATTGGGAAAGGGATGGAAAGTATTTCTGATAATAGCGAGGGACATGCTA
TTACTGGTGCTGAACTTGCTCAAAGTTGCGGAGAGAGCGAAATTGTTGTTAATGCTATTGCTGCGCATCACAATGAGGTG
AAACCCGAGAGTCTTGAGGCTATTGTGGTTCAAATAGCAGATGCCATTTCAGCATCTCGTCCTGGAGCAAGAAGGGAAAG
TTTAAATAACTATATAAATAGACTTAAAAGACTTGAAGACATTGCGTATAGTTTTGAGGGTGTTCAAAAATGTTATGCTA
TTCAGGCAGGTCGTGAAGTTAGAATTATTGTTGACAATGCTTTAATTAATGATGAAAAGTCAATTTTACTTGCAAGAGAT
ATTGCTAAGAAGATAGAAGCTGAAATGAGATATCCTGGAAAAATTAAAGTTACAATTATTCGCGAAACCAGAGTTATTGA
ATATGCAAGATAG

Upstream 100 bases:

>100_bases
AGTTGAAAAGCCTTTAAAAGTTGAATAATTAATAATTTGAGGGCACTGTTTTAAAGATTAAATTTTAAATTGCTTTTAAA
CAGCATAGGAGTTAAATGAT

Downstream 100 bases:

>100_bases
CACTATTAAAACCTTGATAATTGGGGATATAATAGGCGAGAGTGGATTAAAAAAAGTTTTTTTTAATCTTAAAAACATTA
AGAATAAATATAGAATAGAT

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MIYIIFSSIFAGFILGFLVRVFLGRLSLLDLEKNLKKVRVESQLEIENERRQIIANAKSQMLKEKNQQDRDIRDRKNEIV
NLEKRLLQREETLDKRISALDKQQSRVDFKIKEFEQKEKVIREKEADLVKRLENISGLTREDARKIVIEKVEHESKRDAQ
VIINKSEQEAQLLADKVAKDILVSTMQRIVTEVSSEFTVASVELPNDEMKGRIIGKEGRNIRALETLIGADIIIDDTPEA
VVISCFDPIRKELAKRTLERLVTDGRIHPARIEEVVYNVTNEINSIIQEEGEKVVFDLNIHGLDKRLIRGLGRLYFRSSY
GQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHDIGKGMESISDNSEGHAITGAELAQSCGESEIVVNAIAAHHNEV
KPESLEAIVVQIADAISASRPGARRESLNNYINRLKRLEDIAYSFEGVQKCYAIQAGREVRIIVDNALINDEKSILLARD
IAKKIEAEMRYPGKIKVTIIRETRVIEYAR

Sequences:

>Translated_510_residues
MIYIIFSSIFAGFILGFLVRVFLGRLSLLDLEKNLKKVRVESQLEIENERRQIIANAKSQMLKEKNQQDRDIRDRKNEIV
NLEKRLLQREETLDKRISALDKQQSRVDFKIKEFEQKEKVIREKEADLVKRLENISGLTREDARKIVIEKVEHESKRDAQ
VIINKSEQEAQLLADKVAKDILVSTMQRIVTEVSSEFTVASVELPNDEMKGRIIGKEGRNIRALETLIGADIIIDDTPEA
VVISCFDPIRKELAKRTLERLVTDGRIHPARIEEVVYNVTNEINSIIQEEGEKVVFDLNIHGLDKRLIRGLGRLYFRSSY
GQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHDIGKGMESISDNSEGHAITGAELAQSCGESEIVVNAIAAHHNEV
KPESLEAIVVQIADAISASRPGARRESLNNYINRLKRLEDIAYSFEGVQKCYAIQAGREVRIIVDNALINDEKSILLARD
IAKKIEAEMRYPGKIKVTIIRETRVIEYAR
>Mature_510_residues
MIYIIFSSIFAGFILGFLVRVFLGRLSLLDLEKNLKKVRVESQLEIENERRQIIANAKSQMLKEKNQQDRDIRDRKNEIV
NLEKRLLQREETLDKRISALDKQQSRVDFKIKEFEQKEKVIREKEADLVKRLENISGLTREDARKIVIEKVEHESKRDAQ
VIINKSEQEAQLLADKVAKDILVSTMQRIVTEVSSEFTVASVELPNDEMKGRIIGKEGRNIRALETLIGADIIIDDTPEA
VVISCFDPIRKELAKRTLERLVTDGRIHPARIEEVVYNVTNEINSIIQEEGEKVVFDLNIHGLDKRLIRGLGRLYFRSSY
GQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHDIGKGMESISDNSEGHAITGAELAQSCGESEIVVNAIAAHHNEV
KPESLEAIVVQIADAISASRPGARRESLNNYINRLKRLEDIAYSFEGVQKCYAIQAGREVRIIVDNALINDEKSILLARD
IAKKIEAEMRYPGKIKVTIIRETRVIEYAR

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_BORBU (O51457)

Other databases:

- EMBL:   AE000783
- PIR:   G70162
- RefSeq:   NP_212638.1
- ProteinModelPortal:   O51457
- SMR:   O51457
- EnsemblBacteria:   EBBORT00000008783
- GeneID:   1195350
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0504
- NMPDR:   fig|224326.1.peg.888
- TIGR:   BB_0504
- GeneTree:   EBGT00050000006826
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   BBUR224326:BB_0504-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58004; Mature: 58004

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50084 KH_TYPE_1; PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc1b8f20)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYIIFSSIFAGFILGFLVRVFLGRLSLLDLEKNLKKVRVESQLEIENERRQIIANAKSQ
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLKEKNQQDRDIRDRKNEIVNLEKRLLQREETLDKRISALDKQQSRVDFKIKEFEQKEKV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IREKEADLVKRLENISGLTREDARKIVIEKVEHESKRDAQVIINKSEQEAQLLADKVAKD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHEEECCCHHHHHHHHHHHHHH
ILVSTMQRIVTEVSSEFTVASVELPNDEMKGRIIGKEGRNIRALETLIGADIIIDDTPEA
HHHHHHHHHHHHHCCCCEEEEEECCCHHHCCEEECCCCCCHHHHHHHHCCCEEECCCCCE
VVISCFDPIRKELAKRTLERLVTDGRIHPARIEEVVYNVTNEINSIIQEEGEKVVFDLNI
EEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
HGLDKRLIRGLGRLYFRSSYGQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHDIGK
CCHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GMESISDNSEGHAITGAELAQSCGESEIVVNAIAAHHNEVKPESLEAIVVQIADAISASR
HHHHHCCCCCCCEEEHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
PGARRESLNNYINRLKRLEDIAYSFEGVQKCYAIQAGREVRIIVDNALINDEKSILLARD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEECCCHHHHHHHH
IAKKIEAEMRYPGKIKVTIIRETRVIEYAR
HHHHHHHHCCCCCEEEEEEEECCCHHCCCH
>Mature Secondary Structure
MIYIIFSSIFAGFILGFLVRVFLGRLSLLDLEKNLKKVRVESQLEIENERRQIIANAKSQ
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLKEKNQQDRDIRDRKNEIVNLEKRLLQREETLDKRISALDKQQSRVDFKIKEFEQKEKV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IREKEADLVKRLENISGLTREDARKIVIEKVEHESKRDAQVIINKSEQEAQLLADKVAKD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHEEECCCHHHHHHHHHHHHHH
ILVSTMQRIVTEVSSEFTVASVELPNDEMKGRIIGKEGRNIRALETLIGADIIIDDTPEA
HHHHHHHHHHHHHCCCCEEEEEECCCHHHCCEEECCCCCCHHHHHHHHCCCEEECCCCCE
VVISCFDPIRKELAKRTLERLVTDGRIHPARIEEVVYNVTNEINSIIQEEGEKVVFDLNI
EEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEC
HGLDKRLIRGLGRLYFRSSYGQNVLSHSKETAIIGEILAKEMKLDPVVVKRACLLHDIGK
CCHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
GMESISDNSEGHAITGAELAQSCGESEIVVNAIAAHHNEVKPESLEAIVVQIADAISASR
HHHHHCCCCCCCEEEHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
PGARRESLNNYINRLKRLEDIAYSFEGVQKCYAIQAGREVRIIVDNALINDEKSILLARD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEECCCHHHHHHHH
IAKKIEAEMRYPGKIKVTIIRETRVIEYAR
HHHHHHHHCCCCCEEEEEEEECCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9403685