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The map label for this gene is murA [H]

Identifier: 15594817

GI number: 15594817

Start: 490599

End: 491927

Strand: Direct

Name: murA [H]

Synonym: BB0472

Alternate gene names: 15594817

Gene position: 490599-491927 (Clockwise)

Preceding gene: 15594816

Following gene: 15594818

Centisome position: 53.87

GC content: 34.69

Gene sequence:

>1329_bases
GTGCGATTTAATTTTATTAAGTTTTTATATATAGGAGGATGGATTATGCATAGTTATATTGTAGAAGGCGGCTATAAGAT
AGGTGGTCAAATTACAGCTAGTGGGAATAAGAACGCTGCTTTACCCTGTATTTTGGCTGCTTTACTTACCGATGAAGAGG
TTATTTTAGAAAATATTCCTAATATTAATGATGTAAAAGTTGTTTTAGATATTTTAAATGACATAGGAGCAGATATTGCA
AGAGAGGGAAATACTTTAAAAATAAAAGTTTTAAATATTGTGAAAACAGAAATAGATTCTTCTTTTACAGATTTAATTAG
GGCTTCCATACTTTTATTAGGGCCTTTTGTTTCTAGGTTTGGAAAAATAGATATGGCGCTTCCAGGAGGAGATGTGATTG
GAAAGAGGAGGCTTGATACTCATTTTTACGGGCTTTGCAAGCTGGGGGCCAAGTTAAGCACAAAAGATAGAAGGATTGTT
TTAAAGGCTAACAAGCTTGTTGGCGCTGAAATGTTTTTAGATGAAGCTTCTGTTACAGCCACAGAAAATATCATTATGGC
TGCAGTTCTTGCTGAAGGAAATACTGTTATTATGAACGCTGCTTGTGAGCCACATGTTCAAGATTTGTGTAATATGTTAA
ATTCAATGGGCGCTAATATTTTAGGAATTGGTTCAAATGTTTTAGAAATAAAAGGTGTAAAAAAATTAAGTGGGACCGTA
TTTAGAATAGGAGCCGATTTCATGCAAGTTGGTTCTTTAATTAGCCTTGCTGCATTAACAGGGGGTGAGTTGGAAATTAA
AAAAGCAGATCCCCAACATTTCAGATTAATTAGGCATGTATATTCAAGACTTGGCATTAATTTTGAATATGACAGGGAAA
ATGTATATGTAAGAAATAAACAAGAATTAAAAGTTAAGTTAGATTTTGGTGGGCACATTCCAAAAATTGATGATGGCCCA
TGGCCAGCCTTTCCAACAGACCTTATGAGTATTATTGTAGTTACTGCAACGCAAGTAGAAGGCACAGTTTTAGTTTTTGA
GAAGATGTTTGAATCTAGGATGTTTTTTGTAGATAAATTAATAAAAATGGGTGCTCGAATTGTGCTTTGTGATCCACACC
GCGTAGTAGTTACGGGCAAATCTTCTCTTAAAGGCAATGTTTTGTCTTCTCCGGATGTACGAGCGGGAATGTCTCTTCTT
ATTGCTGCTTTTGTTGCTGAAGGTCGCAGCGAGATTCAAAATGTTTATCAAATTGAAAGAGGATACGAAGATGTAGTTAA
CAAATTGATTAATTTGGGTGCAAAAATCAAGAAAGTTAAAAGTCAATAG

Upstream 100 bases:

>100_bases
TTGTTAGAGAATATATAGATTGTAAATCAAGTTTAAAAGATATGGATATTGTTTGATATTCATATCTTTAGATATTCTTT
AAATTTTAATAATCTTATCT

Downstream 100 bases:

>100_bases
CTTGTTGTTGGGCTTTATTATATGTATGATTTGTGGAAAATGTTTTTAATAGAAGGTAAGGATAAGGTATTAAGAGGTTG
AATTGTGAATGAAAATATAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MRFNFIKFLYIGGWIMHSYIVEGGYKIGGQITASGNKNAALPCILAALLTDEEVILENIPNINDVKVVLDILNDIGADIA
REGNTLKIKVLNIVKTEIDSSFTDLIRASILLLGPFVSRFGKIDMALPGGDVIGKRRLDTHFYGLCKLGAKLSTKDRRIV
LKANKLVGAEMFLDEASVTATENIIMAAVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLSGTV
FRIGADFMQVGSLISLAALTGGELEIKKADPQHFRLIRHVYSRLGINFEYDRENVYVRNKQELKVKLDFGGHIPKIDDGP
WPAFPTDLMSIIVVTATQVEGTVLVFEKMFESRMFFVDKLIKMGARIVLCDPHRVVVTGKSSLKGNVLSSPDVRAGMSLL
IAAFVAEGRSEIQNVYQIERGYEDVVNKLINLGAKIKKVKSQ

Sequences:

>Translated_442_residues
MRFNFIKFLYIGGWIMHSYIVEGGYKIGGQITASGNKNAALPCILAALLTDEEVILENIPNINDVKVVLDILNDIGADIA
REGNTLKIKVLNIVKTEIDSSFTDLIRASILLLGPFVSRFGKIDMALPGGDVIGKRRLDTHFYGLCKLGAKLSTKDRRIV
LKANKLVGAEMFLDEASVTATENIIMAAVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLSGTV
FRIGADFMQVGSLISLAALTGGELEIKKADPQHFRLIRHVYSRLGINFEYDRENVYVRNKQELKVKLDFGGHIPKIDDGP
WPAFPTDLMSIIVVTATQVEGTVLVFEKMFESRMFFVDKLIKMGARIVLCDPHRVVVTGKSSLKGNVLSSPDVRAGMSLL
IAAFVAEGRSEIQNVYQIERGYEDVVNKLINLGAKIKKVKSQ
>Mature_442_residues
MRFNFIKFLYIGGWIMHSYIVEGGYKIGGQITASGNKNAALPCILAALLTDEEVILENIPNINDVKVVLDILNDIGADIA
REGNTLKIKVLNIVKTEIDSSFTDLIRASILLLGPFVSRFGKIDMALPGGDVIGKRRLDTHFYGLCKLGAKLSTKDRRIV
LKANKLVGAEMFLDEASVTATENIIMAAVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLSGTV
FRIGADFMQVGSLISLAALTGGELEIKKADPQHFRLIRHVYSRLGINFEYDRENVYVRNKQELKVKLDFGGHIPKIDDGP
WPAFPTDLMSIIVVTATQVEGTVLVFEKMFESRMFFVDKLIKMGARIVLCDPHRVVVTGKSSLKGNVLSSPDVRAGMSLL
IAAFVAEGRSEIQNVYQIERGYEDVVNKLINLGAKIKKVKSQ

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=432, Percent_Identity=35.6481481481481, Blast_Score=259, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 48498; Mature: 48498

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFNFIKFLYIGGWIMHSYIVEGGYKIGGQITASGNKNAALPCILAALLTDEEVILENIP
CCCEEEEHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCHHHHHHHHHHCCCHHHHHCCC
NINDVKVVLDILNDIGADIAREGNTLKIKVLNIVKTEIDSSFTDLIRASILLLGPFVSRF
CCCHHHHHHHHHHHHCHHHHCCCCEEEEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHC
GKIDMALPGGDVIGKRRLDTHFYGLCKLGAKLSTKDRRIVLKANKLVGAEMFLDEASVTA
CCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHCCCCCHH
TENIIMAAVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLSGTV
HHHEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCEEEECCCHHHCCEE
FRIGADFMQVGSLISLAALTGGELEIKKADPQHFRLIRHVYSRLGINFEYDRENVYVRNK
EEECHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCEEEECC
QELKVKLDFGGHIPKIDDGPWPAFPTDLMSIIVVTATQVEGTVLVFEKMFESRMFFVDKL
EEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHH
IKMGARIVLCDPHRVVVTGKSSLKGNVLSSPDVRAGMSLLIAAFVAEGRSEIQNVYQIER
HHCCCEEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYEDVVNKLINLGAKIKKVKSQ
CHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MRFNFIKFLYIGGWIMHSYIVEGGYKIGGQITASGNKNAALPCILAALLTDEEVILENIP
CCCEEEEHHHHHHHHHHHHHHCCCEEECCEEEECCCCCCHHHHHHHHHHCCCHHHHHCCC
NINDVKVVLDILNDIGADIAREGNTLKIKVLNIVKTEIDSSFTDLIRASILLLGPFVSRF
CCCHHHHHHHHHHHHCHHHHCCCCEEEEEEEEEHHHHHCHHHHHHHHHHHHHHHHHHHHC
GKIDMALPGGDVIGKRRLDTHFYGLCKLGAKLSTKDRRIVLKANKLVGAEMFLDEASVTA
CCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHCCCCCHH
TENIIMAAVLAEGNTVIMNAACEPHVQDLCNMLNSMGANILGIGSNVLEIKGVKKLSGTV
HHHEEEEEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCEEEECCCHHHCCEE
FRIGADFMQVGSLISLAALTGGELEIKKADPQHFRLIRHVYSRLGINFEYDRENVYVRNK
EEECHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCEEEECC
QELKVKLDFGGHIPKIDDGPWPAFPTDLMSIIVVTATQVEGTVLVFEKMFESRMFFVDKL
EEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHH
IKMGARIVLCDPHRVVVTGKSSLKGNVLSSPDVRAGMSLLIAAFVAEGRSEIQNVYQIER
HHCCCEEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GYEDVVNKLINLGAKIKKVKSQ
CHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]