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The map label for this gene is rnpA

Identifier: 15594786

GI number: 15594786

Start: 460052

End: 460411

Strand: Direct

Name: rnpA

Synonym: BB0441

Alternate gene names: 15594786

Gene position: 460052-460411 (Clockwise)

Preceding gene: 15594785

Following gene: 15594787

Centisome position: 50.51

GC content: 27.5

Gene sequence:

>360_bases
ATGAGAAAAAGAAATATTAGTTTAAAATCAAAAATAGAAATTCAAAAAATTTTCAAAGAAGGCAAGCTGATTAGATTTAG
CAATCTTAATCTTAAAATGTTCTATAAATCAAATCATTTGGTTTATTCTAGAATTCTTGTTACCTTTTCTAAAGGCTTTA
GGGGATCTGTTAAAAGGAATCGCATTAGAAGACTTTTTAAAGAAGCTTTTAGAAAAAGATTAGAATTGTTAGAAGGGATT
GCTTTAGATATTATTTTTGTAGTTTCTTATGGTAAGTTAACTTTGACTTATTTTAGCATTGAATCTCTCATGAAAGGTTT
GGTTTTAAGGTGTGAAAGGGGCATAGGTGAATCAAAGTAG

Upstream 100 bases:

>100_bases
AATAGAAAATTTGGGTTTAGAGCTAGAATGAAAACTAAAGGCGGAAGACTTATTCTTTCAAGGCGAAGGGCAAAAGGAAG
AATGAAATTAACTGTTTCTG

Downstream 100 bases:

>100_bases
AAGAATTTTAAGAACAGTTTATTTGTCTTTATTTTTAATAGGTCTTTTCATGCTTATTAATGATATTTTTTCTTCAAACA
TTTTAAGTTCTAAGTCTTCT

Product: ribonuclease P

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MRKRNISLKSKIEIQKIFKEGKLIRFSNLNLKMFYKSNHLVYSRILVTFSKGFRGSVKRNRIRRLFKEAFRKRLELLEGI
ALDIIFVVSYGKLTLTYFSIESLMKGLVLRCERGIGESK

Sequences:

>Translated_119_residues
MRKRNISLKSKIEIQKIFKEGKLIRFSNLNLKMFYKSNHLVYSRILVTFSKGFRGSVKRNRIRRLFKEAFRKRLELLEGI
ALDIIFVVSYGKLTLTYFSIESLMKGLVLRCERGIGESK
>Mature_119_residues
MRKRNISLKSKIEIQKIFKEGKLIRFSNLNLKMFYKSNHLVYSRILVTFSKGFRGSVKRNRIRRLFKEAFRKRLELLEGI
ALDIIFVVSYGKLTLTYFSIESLMKGLVLRCERGIGESK

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_BORBU (P50069)

Other databases:

- EMBL:   AE000783
- EMBL:   U04527
- PIR:   H70154
- RefSeq:   NP_212575.1
- ProteinModelPortal:   P50069
- EnsemblBacteria:   EBBORT00000008466
- GeneID:   1195286
- GenomeReviews:   AE000783_GR
- KEGG:   bbu:BB0441
- NMPDR:   fig|224326.1.peg.825
- TIGR:   BB_0441
- GeneTree:   EBGT00050000007545
- HOGENOM:   HBG354435
- OMA:   GSVKRNR
- ProtClustDB:   CLSK507595
- BioCyc:   BBUR224326:BB_0441-MONOMER
- BRENDA:   3.1.26.5
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 14052; Mature: 14052

Theoretical pI: Translated: 11.43; Mature: 11.43

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRNISLKSKIEIQKIFKEGKLIRFSNLNLKMFYKSNHLVYSRILVTFSKGFRGSVKRN
CCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHH
RIRRLFKEAFRKRLELLEGIALDIIFVVSYGKLTLTYFSIESLMKGLVLRCERGIGESK
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKRNISLKSKIEIQKIFKEGKLIRFSNLNLKMFYKSNHLVYSRILVTFSKGFRGSVKRN
CCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHH
RIRRLFKEAFRKRLELLEGIALDIIFVVSYGKLTLTYFSIESLMKGLVLRCERGIGESK
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685; 7921235