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The map label for this gene is frr [H]

Identifier: 15594466

GI number: 15594466

Start: 118375

End: 118929

Strand: Reverse

Name: frr [H]

Synonym: BB0121

Alternate gene names: 15594466

Gene position: 118929-118375 (Counterclockwise)

Preceding gene: 15594467

Following gene: 15594465

Centisome position: 13.06

GC content: 28.65

Gene sequence:

>555_bases
ATGGAAGATTATAAGGCTTTTCTAGATGAAAAGATGAACAAGGTTCTTTTATCACTTGATAATGAATATAAAACGTTAAG
AACAGGTAGAATTAGTAGTAATATTTTTGATAGAATTTGTATTCAATACCATGACCGAAGAACACCTATAACTCAAGTGT
CAAGTATTAGAATTCCTGAAGCAAGGCTTGTTGTTATTCAGCCTTGGGATAAAAGCATCTTAAATAAGATAGAGCAAGCC
ATACTTAATTCTGATCTTTCTATGAATCCTTCAAATGATGGTTCAGTTATTAGAATTAAGGTTCCAAATTTAACTAGTGA
AAGGCGACAAGAGATTGTAAAGCATGCTAAAAAAATAGCAGAAGAACATAAAATTTCAACTAGAAATATACGACAGGATT
TAAACAATAAAGTTAAAAAGCAAGAAAAAGAATCGGAAATTACAGAGGACTGTTTAAAAAGAATTTTAGATGATATTCAG
AAATCCACAGATATGTATATTAAAAAGATAGATTCAATTTTAGAATCTAAAATTCAAGAAATAATGGAAGCTTAA

Upstream 100 bases:

>100_bases
GAAATTTCAAAAGCAATTTCAAGCAAGGTAGAAATGGTTGAGTTTAAATATTTAAGAATAGGGTAGATAATGTGCTCTTT
ATCAGCAAGGAGGAGTTTAT

Downstream 100 bases:

>100_bases
ATCCATGAATAAAGGTTCTCTTCCAAGTCATGTTGGAATTATTATGGATGGCAATAGAAGGTGGGCTTTAGGTAAAAGAT
TGTCTTCTTTAGAAGGTTAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MEDYKAFLDEKMNKVLLSLDNEYKTLRTGRISSNIFDRICIQYHDRRTPITQVSSIRIPEARLVVIQPWDKSILNKIEQA
ILNSDLSMNPSNDGSVIRIKVPNLTSERRQEIVKHAKKIAEEHKISTRNIRQDLNNKVKKQEKESEITEDCLKRILDDIQ
KSTDMYIKKIDSILESKIQEIMEA

Sequences:

>Translated_184_residues
MEDYKAFLDEKMNKVLLSLDNEYKTLRTGRISSNIFDRICIQYHDRRTPITQVSSIRIPEARLVVIQPWDKSILNKIEQA
ILNSDLSMNPSNDGSVIRIKVPNLTSERRQEIVKHAKKIAEEHKISTRNIRQDLNNKVKKQEKESEITEDCLKRILDDIQ
KSTDMYIKKIDSILESKIQEIMEA
>Mature_184_residues
MEDYKAFLDEKMNKVLLSLDNEYKTLRTGRISSNIFDRICIQYHDRRTPITQVSSIRIPEARLVVIQPWDKSILNKIEQA
ILNSDLSMNPSNDGSVIRIKVPNLTSERRQEIVKHAKKIAEEHKISTRNIRQDLNNKVKKQEKESEITEDCLKRILDDIQ
KSTDMYIKKIDSILESKIQEIMEA

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=30.3370786516854, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786368, Length=173, Percent_Identity=38.728323699422, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21539; Mature: 21539

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDYKAFLDEKMNKVLLSLDNEYKTLRTGRISSNIFDRICIQYHDRRTPITQVSSIRIPE
CCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
ARLVVIQPWDKSILNKIEQAILNSDLSMNPSNDGSVIRIKVPNLTSERRQEIVKHAKKIA
CEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
EEHKISTRNIRQDLNNKVKKQEKESEITEDCLKRILDDIQKSTDMYIKKIDSILESKIQE
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMEA
HHHC
>Mature Secondary Structure
MEDYKAFLDEKMNKVLLSLDNEYKTLRTGRISSNIFDRICIQYHDRRTPITQVSSIRIPE
CCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCC
ARLVVIQPWDKSILNKIEQAILNSDLSMNPSNDGSVIRIKVPNLTSERRQEIVKHAKKIA
CEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
EEHKISTRNIRQDLNNKVKKQEKESEITEDCLKRILDDIQKSTDMYIKKIDSILESKIQE
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMEA
HHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA