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The map label for this gene is dnaB [H]

Identifier: 15594457

GI number: 15594457

Start: 109675

End: 111042

Strand: Reverse

Name: dnaB [H]

Synonym: BB0111

Alternate gene names: 15594457

Gene position: 111042-109675 (Counterclockwise)

Preceding gene: 15594458

Following gene: 15594455

Centisome position: 12.19

GC content: 31.65

Gene sequence:

>1368_bases
GTGGCTTTAGCAGCTTTTTCGAATTCTGCACTTCTTTTTAATGATGGTGCAGAAAAAGCGGTAATTTCTAGTATATTTTA
TAATTCAGATAAGATAGAGCAAATTGCTTTTCATGTAAGAGCTGATGATTTTTACAATGAAACTCATAAGTTGATTTTCA
AAGCAATGGTTTCGCTTTATGAAAAAAGGGAAAATATTGATCCTATTACTGTTTTTGAAGAAGTATCTAAGCATGTTTCA
AAAACGCAACTTTTGATTAAAAAAGATTTAATCAATTTGCCTGATTATTTAGATTCACTTTCAGTTTATTTGCCAACAGA
TAGAACTATAAATGTTTATGCGAAAATTGTAAAAGAACAGAGTGTTCGCAGAAGCATTTTAAATGTTTCTAAAGAGCTTA
ATGACTATATAAATGATTCTACAAAATCTATTAATGAGATTGTTGAAGAATCTCAACAAAAGATTCTTTCAATTGAGTTA
GATTATTCTAGTAAGAACCTCTATCATGCTAAAGTTATTGCAGAACGTGTTCATAATGAGATATATGAGCGCAGCATGAA
GAAAAAAGAAGCAAACTTTGGCATTCCAAGTGGCTTTAGAAAGGTCGACTCTCTTATTGGGGGATTTAGAAATAGTGATT
TTATTATAGTTGGTGCTCGTCCTAGCATCGGTAAAACGGCATTTGCTTTAAATATTGCTTCTTATATAGCATTAAGAAAA
GAAGAAAAGAAAAAAGTAGGATTTTTTTCCCTTGAAATGACAGCAGATGCTTTAATAAAAAGAATAATATCTTCTCAGTC
TTGTATTGATAGCTTTAAAGTTCAAAATAGCATTTTATCTGGACAAGAGATAAAATCATTAAATGATATTATAAATGAAA
TTAGTGATTCTGAGCTTTATATTGAAGATACTCCCAATATTAGTTTGCTAACTTTGGCAACTCAAGCTAGAAAACTTAAG
CGATTTTATGGTATAGATATAATATTTGTTGATTATATCAGTCTGATTTCTTTTGAAACAAAAAATCTTCCAAGGCATGA
ACAAGTTGCTTCGATTAGTAAATCTCTCAAAGAGCTTGCTAGAGAGCTTGAGATTCCTATTGTCGCATTATCTCAGCTTA
CAAGAGATACGGAAGGGCGTGAGCCTAATCTTGCTAGTCTAAGGGAATCAGGAGCATTGGAGCAAGATGCTGACATTGTA
ATTTTACTTCATAGGGATAAGGATTTTAAATTTGAGTCTTCTGCTGAGATAGAACCAATAGAAACCAAGGTTATTGTAGC
AAAACATAGAAATGGCCCTACAGGTAGGGCAGATATATTATTTTTGCCACACATTACTAAGTTTGTTAACAAAGACCACC
AGTATTAG

Upstream 100 bases:

>100_bases
AGTAGAGATAAAAAAAGAAAAAAAGCAAGAGGATAAAAAGTCTTTAAGTAAAAAGTTGAATAAAGCAGATGAGCAAGGTG
AAAGAGCAGAGGTGTAGTTT

Downstream 100 bases:

>100_bases
TTGTTATTTAACGACTATTCCAATTCCTAAATAATTAAAGTTAATAGAATGTTTTTCTAATTTTTTTTCATCTAAGTTAT
AAGCTATAGGAATATAGTTA

Product: DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MALAAFSNSALLFNDGAEKAVISSIFYNSDKIEQIAFHVRADDFYNETHKLIFKAMVSLYEKRENIDPITVFEEVSKHVS
KTQLLIKKDLINLPDYLDSLSVYLPTDRTINVYAKIVKEQSVRRSILNVSKELNDYINDSTKSINEIVEESQQKILSIEL
DYSSKNLYHAKVIAERVHNEIYERSMKKKEANFGIPSGFRKVDSLIGGFRNSDFIIVGARPSIGKTAFALNIASYIALRK
EEKKKVGFFSLEMTADALIKRIISSQSCIDSFKVQNSILSGQEIKSLNDIINEISDSELYIEDTPNISLLTLATQARKLK
RFYGIDIIFVDYISLISFETKNLPRHEQVASISKSLKELARELEIPIVALSQLTRDTEGREPNLASLRESGALEQDADIV
ILLHRDKDFKFESSAEIEPIETKVIVAKHRNGPTGRADILFLPHITKFVNKDHQY

Sequences:

>Translated_455_residues
MALAAFSNSALLFNDGAEKAVISSIFYNSDKIEQIAFHVRADDFYNETHKLIFKAMVSLYEKRENIDPITVFEEVSKHVS
KTQLLIKKDLINLPDYLDSLSVYLPTDRTINVYAKIVKEQSVRRSILNVSKELNDYINDSTKSINEIVEESQQKILSIEL
DYSSKNLYHAKVIAERVHNEIYERSMKKKEANFGIPSGFRKVDSLIGGFRNSDFIIVGARPSIGKTAFALNIASYIALRK
EEKKKVGFFSLEMTADALIKRIISSQSCIDSFKVQNSILSGQEIKSLNDIINEISDSELYIEDTPNISLLTLATQARKLK
RFYGIDIIFVDYISLISFETKNLPRHEQVASISKSLKELARELEIPIVALSQLTRDTEGREPNLASLRESGALEQDADIV
ILLHRDKDFKFESSAEIEPIETKVIVAKHRNGPTGRADILFLPHITKFVNKDHQY
>Mature_454_residues
ALAAFSNSALLFNDGAEKAVISSIFYNSDKIEQIAFHVRADDFYNETHKLIFKAMVSLYEKRENIDPITVFEEVSKHVSK
TQLLIKKDLINLPDYLDSLSVYLPTDRTINVYAKIVKEQSVRRSILNVSKELNDYINDSTKSINEIVEESQQKILSIELD
YSSKNLYHAKVIAERVHNEIYERSMKKKEANFGIPSGFRKVDSLIGGFRNSDFIIVGARPSIGKTAFALNIASYIALRKE
EKKKVGFFSLEMTADALIKRIISSQSCIDSFKVQNSILSGQEIKSLNDIINEISDSELYIEDTPNISLLTLATQARKLKR
FYGIDIIFVDYISLISFETKNLPRHEQVASISKSLKELARELEIPIVALSQLTRDTEGREPNLASLRESGALEQDADIVI
LLHRDKDFKFESSAEIEPIETKVIVAKHRNGPTGRADILFLPHITKFVNKDHQY

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity [H]

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=445, Percent_Identity=31.0112359550562, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 51663; Mature: 51531

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAAFSNSALLFNDGAEKAVISSIFYNSDKIEQIAFHVRADDFYNETHKLIFKAMVSLY
CEEEEECCCEEEECCCCHHHHHHHHHCCCCHHHHHHEEEECHHHHHHHHHHHHHHHHHHH
EKRENIDPITVFEEVSKHVSKTQLLIKKDLINLPDYLDSLSVYLPTDRTINVYAKIVKEQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCHHHHHHHHHHHH
SVRRSILNVSKELNDYINDSTKSINEIVEESQQKILSIELDYSSKNLYHAKVIAERVHNE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHH
IYERSMKKKEANFGIPSGFRKVDSLIGGFRNSDFIIVGARPSIGKTAFALNIASYIALRK
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
EEKKKVGFFSLEMTADALIKRIISSQSCIDSFKVQNSILSGQEIKSLNDIINEISDSELY
HHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEE
IEDTPNISLLTLATQARKLKRFYGIDIIFVDYISLISFETKNLPRHEQVASISKSLKELA
EECCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RELEIPIVALSQLTRDTEGREPNLASLRESGALEQDADIVILLHRDKDFKFESSAEIEPI
HHHCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
ETKVIVAKHRNGPTGRADILFLPHITKFVNKDHQY
CEEEEEEECCCCCCCCEEEEECHHHHHHHCCCCCC
>Mature Secondary Structure 
ALAAFSNSALLFNDGAEKAVISSIFYNSDKIEQIAFHVRADDFYNETHKLIFKAMVSLY
EEEEECCCEEEECCCCHHHHHHHHHCCCCHHHHHHEEEECHHHHHHHHHHHHHHHHHHH
EKRENIDPITVFEEVSKHVSKTQLLIKKDLINLPDYLDSLSVYLPTDRTINVYAKIVKEQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCHHHHHHHHHHHH
SVRRSILNVSKELNDYINDSTKSINEIVEESQQKILSIELDYSSKNLYHAKVIAERVHNE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHH
IYERSMKKKEANFGIPSGFRKVDSLIGGFRNSDFIIVGARPSIGKTAFALNIASYIALRK
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHH
EEKKKVGFFSLEMTADALIKRIISSQSCIDSFKVQNSILSGQEIKSLNDIINEISDSELY
HHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEE
IEDTPNISLLTLATQARKLKRFYGIDIIFVDYISLISFETKNLPRHEQVASISKSLKELA
EECCCCEEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RELEIPIVALSQLTRDTEGREPNLASLRESGALEQDADIVILLHRDKDFKFESSAEIEPI
HHHCCCHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
ETKVIVAKHRNGPTGRADILFLPHITKFVNKDHQY
CEEEEEEECCCCCCCCEEEEECHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]