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The map label for this gene is yybE

Identifier: 255767875

GI number: 255767875

Start: 4180564

End: 4181442

Strand: Direct

Name: yybE

Synonym: BSU40670

Alternate gene names: 255767875

Gene position: 4180564-4181442 (Clockwise)

Preceding gene: 16081117

Following gene: 16081120

Centisome position: 99.17

GC content: 46.76

Gene sequence:

>879_bases
TTGGAATGGGAACAACTTGAATATTTTCAAACACTGGCCCGGATGCAGCACGTCACGAAAGCCGCAAAAAGCCTCTCCAT
CACACAGCCTGCACTTTCACGCTCTATCGCCAGGCTGGAAAATCATTTGGGCGTCCCGCTATTTGACAGGCAAGGACGAT
CCATCAGCTTAAATCAATACGGACACATTTTTTTACGACGGGTTCAGGCGATGATGAAGGAGTATACCGAAGGAAAAGAA
GAAATCCAAGCCTTATTAAAGCCAGACCAAGGCGTAGTCTCTCTCGGTTTTTTACATACATTAGGCACCACGCTCGTGCC
CGATCTCATCGGCTCCTTTCAGCAGGAATACCCCAACATTTCCTTCCAGCTGAAGCAAAACCACTCTTATTGGCTGCTTG
AACGATTAAAATCCGGAGATCTGGACCTCTGTCTCCTCGCTTCGATTAAGCCTGAAAATCCGATCCAATGGATCAAGCTG
TGGAGTGAAGAACTCTTTGTATTTGTGCCAAATGATCACCCATTAGCCAGTCGCGAAAGCATTACCCTGAATGAGATTGC
CGGGGAGCGTTTTATTTTATTGAAAAAGGGCTATGCGCTTCGGATGACGGTCGATGAGCTGTTTGAGAAGGCCAATATAC
AGCCGAACATTATGTTTGAAGGAGAAGAAGCAACTACTGCCGCAGGTTTTGTGGCAGCCGGTCTGGGCATATCTATTCTC
CCAGACCTGAAAGGCTTAGACCAAAGCAAAATCACCAAAATCCGCGTCAGCTGGCCGGAATGTCAGCGTGTCATAGGAAT
TGCCTGGATAAAAGGCAGGTTTTTATCACCGGTTGCTGAGACCTTTAAACAATATGTGATCAGCCATTTTTCTGAGTAG

Upstream 100 bases:

>100_bases
CGAGTCTGTTTATATTATTATCTTAGCACCGTTGATATATGTTGTATAATGCATATAAAATATCCTTTTCATGCTTATAT
GTAATAAGGAGAGATGATAA

Downstream 100 bases:

>100_bases
GAAGGATTCAAGCATGAATGTCAAAAAAATCACGTCAGAACAGGATTTACATACAGCGTTTGAAATCAGAAAGGCAGTAT
TTGTAGAGGAACAAGGCTGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MEWEQLEYFQTLARMQHVTKAAKSLSITQPALSRSIARLENHLGVPLFDRQGRSISLNQYGHIFLRRVQAMMKEYTEGKE
EIQALLKPDQGVVSLGFLHTLGTTLVPDLIGSFQQEYPNISFQLKQNHSYWLLERLKSGDLDLCLLASIKPENPIQWIKL
WSEELFVFVPNDHPLASRESITLNEIAGERFILLKKGYALRMTVDELFEKANIQPNIMFEGEEATTAAGFVAAGLGISIL
PDLKGLDQSKITKIRVSWPECQRVIGIAWIKGRFLSPVAETFKQYVISHFSE

Sequences:

>Translated_292_residues
MEWEQLEYFQTLARMQHVTKAAKSLSITQPALSRSIARLENHLGVPLFDRQGRSISLNQYGHIFLRRVQAMMKEYTEGKE
EIQALLKPDQGVVSLGFLHTLGTTLVPDLIGSFQQEYPNISFQLKQNHSYWLLERLKSGDLDLCLLASIKPENPIQWIKL
WSEELFVFVPNDHPLASRESITLNEIAGERFILLKKGYALRMTVDELFEKANIQPNIMFEGEEATTAAGFVAAGLGISIL
PDLKGLDQSKITKIRVSWPECQRVIGIAWIKGRFLSPVAETFKQYVISHFSE
>Mature_292_residues
MEWEQLEYFQTLARMQHVTKAAKSLSITQPALSRSIARLENHLGVPLFDRQGRSISLNQYGHIFLRRVQAMMKEYTEGKE
EIQALLKPDQGVVSLGFLHTLGTTLVPDLIGSFQQEYPNISFQLKQNHSYWLLERLKSGDLDLCLLASIKPENPIQWIKL
WSEELFVFVPNDHPLASRESITLNEIAGERFILLKKGYALRMTVDELFEKANIQPNIMFEGEEATTAAGFVAAGLGISIL
PDLKGLDQSKITKIRVSWPECQRVIGIAWIKGRFLSPVAETFKQYVISHFSE

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=29.0969899665552, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=28.0821917808219, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI157672245, Length=282, Percent_Identity=26.5957446808511, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693105, Length=293, Percent_Identity=28.3276450511945, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=29.6296296296296, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788748, Length=280, Percent_Identity=27.8571428571429, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788297, Length=243, Percent_Identity=27.5720164609054, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787530, Length=264, Percent_Identity=23.4848484848485, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=26.551724137931, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1789204, Length=247, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=25.2032520325203, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787806, Length=241, Percent_Identity=26.1410788381743, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI2367136, Length=238, Percent_Identity=24.3697478991597, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787601, Length=245, Percent_Identity=22.4489795918367, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790262, Length=242, Percent_Identity=24.3801652892562, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081904, Length=211, Percent_Identity=25.5924170616114, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790208, Length=306, Percent_Identity=23.8562091503268, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789506, Length=142, Percent_Identity=27.4647887323944, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790783, Length=283, Percent_Identity=24.3816254416961, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786401, Length=133, Percent_Identity=27.8195488721804, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789173, Length=121, Percent_Identity=32.2314049586777, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YYBE_BACSU (P37499)

Other databases:

- EMBL:   D26185
- EMBL:   AL009126
- PIR:   S65992
- RefSeq:   NP_391947.2
- ProteinModelPortal:   P37499
- SMR:   P37499
- EnsemblBacteria:   EBBACT00000001386
- GeneID:   937875
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU40670
- NMPDR:   fig|224308.1.peg.4073
- GenoList:   BSU40670
- GeneTree:   EBGT00070000031895
- HOGENOM:   HBG685425
- ProtClustDB:   CLSK888203
- BioCyc:   BSUB:BSU40670-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 33233; Mature: 33233

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWEQLEYFQTLARMQHVTKAAKSLSITQPALSRSIARLENHLGVPLFDRQGRSISLNQY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCEEEHHHH
GHIFLRRVQAMMKEYTEGKEEIQALLKPDQGVVSLGFLHTLGTTLVPDLIGSFQQEYPNI
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCE
SFQLKQNHSYWLLERLKSGDLDLCLLASIKPENPIQWIKLWSEELFVFVPNDHPLASRES
EEEEECCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCC
ITLNEIAGERFILLKKGYALRMTVDELFEKANIQPNIMFEGEEATTAAGFVAAGLGISIL
EEHHHHCCCEEEEEECCCEEEEEHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCEEC
PDLKGLDQSKITKIRVSWPECQRVIGIAWIKGRFLSPVAETFKQYVISHFSE
CCCCCCCCHHEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEWEQLEYFQTLARMQHVTKAAKSLSITQPALSRSIARLENHLGVPLFDRQGRSISLNQY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEECCCCCEEEHHHH
GHIFLRRVQAMMKEYTEGKEEIQALLKPDQGVVSLGFLHTLGTTLVPDLIGSFQQEYPNI
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCE
SFQLKQNHSYWLLERLKSGDLDLCLLASIKPENPIQWIKLWSEELFVFVPNDHPLASRES
EEEEECCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCC
ITLNEIAGERFILLKKGYALRMTVDELFEKANIQPNIMFEGEEATTAAGFVAAGLGISIL
EEHHHHCCCEEEEEECCCEEEEEHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCCEEC
PDLKGLDQSKITKIRVSWPECQRVIGIAWIKGRFLSPVAETFKQYVISHFSE
CCCCCCCCHHEEEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377