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The map label for this gene is ywcA

Identifier: 255767812

GI number: 255767812

Start: 3924225

End: 3925766

Strand: Direct

Name: ywcA

Synonym: BSU38240

Alternate gene names: 255767812

Gene position: 3924225-3925766 (Clockwise)

Preceding gene: 16080874

Following gene: 16080883

Centisome position: 93.09

GC content: 50.32

Gene sequence:

>1542_bases
ATGAATATGACTGCTTTTTTATTATTTTTGGCGATTGTTGGCCTGACGCTTATTATCACGTATTTTGCCGCGAAGCGGAC
GAAAACGACGAGTGAGTTTTATACGGCGGGCGGCGGGCTCACCGGCGTTCAGAATGGACTGGCAATTGCCGGTGACTACA
TGTCTGCCGCCTCGTTTCTCGGGATTGCCGGAATGATTGCGTTATATGGATTTGATGGCTTCTTTTACAGCATCGGTTTT
CTGGTGGCTTATCTCGTTGTCTTGTACATCGTGGCGGAGCCGCTTCGGAATCTTGGAAAGTACACGATGGCAGACATGAT
TGCCGCTCGCTTTAAAGAAAAGAAAATCCGCGGTGTCGCGGCTCTCAATACCATTGCCATCTCTACTTTTTATATGATCG
CCCAGCTCGTGGGGGCGGGCGCGCTGATCAAACTGCTTCTAGGGCTGGATTATACCGCGGCTGTCCTCATCGTCGGAGTG
CTGATGACCATTTATGTCGTGTTTGGCGGCATGATCGCGACAAGCTGGGTTCAAATTATTAAAGCTGTTTTGCTGATGGC
CGGCACACTCGTGATTTCGATTATCGTGTTTTCGAAATTCGGCTTTAGCCTTAATACCATGTTTGAACAGATGAAAACGG
CTACTCCGCTTGGCGCTGATTTTTTGAACCCCGGAAATAAATACAAGGTGCCGCTTGAGACCTTGTCGTTAAACTTGGCA
CTCGTGCTGGGAACCGCCGGGCTTCCGCATATATTGATCCGGTTTTATACCGTTAAGGATGCCAAGACGGCCCGTACATC
CGTTGTGTCAGCGACATGGATTATCGGTGTGTTTTACATTATGACGGTATTTCTCGGCTTTGGTGCCGCGGCATTTGTCG
GTTTTGACGCGATTACGGCGGCTGATCAAGCGGGAAATATGGCGGCTCCGCTTTTAGCAAAAGCGCTCGGAGGAGACTTT
CTGTTCGCGTTTGTATCAGCCATCGCCTTTGCCACCATTTTGGCTGTCGTGACAGGGTTGGTGCTGTCTGCCGCCTCAGC
ATTTGCCCATGATATTTACAGCCAGATCATCAGAAAGGGAGAAGCAACTGAAAAAGAACAAATGAAAGCGGCCAGATGGG
CTTCTGTCGCCGTGTCAGTGCTCTCGATTCTCCTTGCGATTTTTGCACAATCCTTAAATGTGGCGTTCCTTGTTGCACTC
GCGTTTGCGGTAGCCGCCAGCGCAAACCTTCCGCTGATTGTGTTTACAGTCTTCTGGAAACGATTCAATGCCTCAGGCGC
TTTATGGGGCAGCCTGACAGGCCTGATCAGCGCGCTTGTGCTGGTATCGATGAGCCCTAGTGTGTGGGACCCGGCCGGAG
GTGCTATTTTTACCGGTGATCCGCTCATTCCGCTATCTAATCCAGGAATTATTTCCATCCCGCTCGGCTTTCTCGGCGCG
TGGCTCGGAACGGTGCTGTCGTCTGATAAAACAATTGATGAAGATACGTTTGCAGAAATTCAGGTGAAGGCGCATACTGG
CGTCCATATGGAACAGGAATAA

Upstream 100 bases:

>100_bases
TCGCTATGACCTGGATACTGAGTACTGTGTATTCCCGGAGAGCCGCCCATTTCGATAAGTATGTAAGCGCTTTAAAAGAG
GATCTGAAGGGTGAACAGAC

Downstream 100 bases:

>100_bases
AAAAAGCTCTCTTTATCGAGAGCTTTTTCCTTACTTTTTCTTCTGCTCGTCAGAAATCGCTTTTTCAAATACATCCTTGC
CGGCAGCACCCGGAATTACA

Product: acetate Na+-dependent symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MNMTAFLLFLAIVGLTLIITYFAAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFLGIAGMIALYGFDGFFYSIGF
LVAYLVVLYIVAEPLRNLGKYTMADMIAARFKEKKIRGVAALNTIAISTFYMIAQLVGAGALIKLLLGLDYTAAVLIVGV
LMTIYVVFGGMIATSWVQIIKAVLLMAGTLVISIIVFSKFGFSLNTMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
LVLGTAGLPHILIRFYTVKDAKTARTSVVSATWIIGVFYIMTVFLGFGAAAFVGFDAITAADQAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGEATEKEQMKAARWASVAVSVLSILLAIFAQSLNVAFLVAL
AFAVAASANLPLIVFTVFWKRFNASGALWGSLTGLISALVLVSMSPSVWDPAGGAIFTGDPLIPLSNPGIISIPLGFLGA
WLGTVLSSDKTIDEDTFAEIQVKAHTGVHMEQE

Sequences:

>Translated_513_residues
MNMTAFLLFLAIVGLTLIITYFAAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFLGIAGMIALYGFDGFFYSIGF
LVAYLVVLYIVAEPLRNLGKYTMADMIAARFKEKKIRGVAALNTIAISTFYMIAQLVGAGALIKLLLGLDYTAAVLIVGV
LMTIYVVFGGMIATSWVQIIKAVLLMAGTLVISIIVFSKFGFSLNTMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
LVLGTAGLPHILIRFYTVKDAKTARTSVVSATWIIGVFYIMTVFLGFGAAAFVGFDAITAADQAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGEATEKEQMKAARWASVAVSVLSILLAIFAQSLNVAFLVAL
AFAVAASANLPLIVFTVFWKRFNASGALWGSLTGLISALVLVSMSPSVWDPAGGAIFTGDPLIPLSNPGIISIPLGFLGA
WLGTVLSSDKTIDEDTFAEIQVKAHTGVHMEQE
>Mature_513_residues
MNMTAFLLFLAIVGLTLIITYFAAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFLGIAGMIALYGFDGFFYSIGF
LVAYLVVLYIVAEPLRNLGKYTMADMIAARFKEKKIRGVAALNTIAISTFYMIAQLVGAGALIKLLLGLDYTAAVLIVGV
LMTIYVVFGGMIATSWVQIIKAVLLMAGTLVISIIVFSKFGFSLNTMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
LVLGTAGLPHILIRFYTVKDAKTARTSVVSATWIIGVFYIMTVFLGFGAAAFVGFDAITAADQAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKGEATEKEQMKAARWASVAVSVLSILLAIFAQSLNVAFLVAL
AFAVAASANLPLIVFTVFWKRFNASGALWGSLTGLISALVLVSMSPSVWDPAGGAIFTGDPLIPLSNPGIISIPLGFLGA
WLGTVLSSDKTIDEDTFAEIQVKAHTGVHMEQE

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family

Homologues:

Organism=Homo sapiens, GI310128183, Length=436, Percent_Identity=24.5412844036697, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1790503, Length=519, Percent_Identity=46.4354527938343, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1787251, Length=436, Percent_Identity=26.3761467889908, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87082237, Length=440, Percent_Identity=24.3181818181818, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWCA_BACSU (P39599)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39686
- RefSeq:   NP_391703.2
- ProteinModelPortal:   P39599
- EnsemblBacteria:   EBBACT00000001628
- GeneID:   937320
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38240
- NMPDR:   fig|224308.1.peg.3829
- GenoList:   BSU38240
- GeneTree:   EBGT00070000031818
- HOGENOM:   HBG533958
- ProtClustDB:   CLSK2460966
- BioCyc:   BSUB:BSU38240-MONOMER
- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900
- TIGRFAMs:   TIGR00813

Pfam domain/function: PF00474 SSF

EC number: NA

Molecular weight: Translated: 54244; Mature: 54244

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00456 NA_SOLUT_SYMP_1; PS00457 NA_SOLUT_SYMP_2; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1334cbb0)-; HASH(0x133727cc)-; HASH(0x12ec7004)-; HASH(0x13121c20)-; HASH(0x12b5358c)-; HASH(0xdfac9e4)-; HASH(0x1336f8c8)-; HASH(0x13336b7c)-; HASH(0x1335e1f0)-; HASH(0xdfacb28)-; HASH(0x13372ae4)-; HASH(0x13317ff0)-; HASH(0x1336f82c)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMTAFLLFLAIVGLTLIITYFAAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHCCCCEEECHHHHHHHHH
GIAGMIALYGFDGFFYSIGFLVAYLVVLYIVAEPLRNLGKYTMADMIAARFKEKKIRGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNTIAISTFYMIAQLVGAGALIKLLLGLDYTAAVLIVGVLMTIYVVFGGMIATSWVQII
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVLLMAGTLVISIIVFSKFGFSLNTMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHCCCCCCEECCHHHHHHHHH
LVLGTAGLPHILIRFYTVKDAKTARTSVVSATWIIGVFYIMTVFLGFGAAAFVGFDAITA
EEEECCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADQAGNMAAPLLAKALGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKG
HHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EATEKEQMKAARWASVAVSVLSILLAIFAQSLNVAFLVALAFAVAASANLPLIVFTVFWK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RFNASGALWGSLTGLISALVLVSMSPSVWDPAGGAIFTGDPLIPLSNPGIISIPLGFLGA
HHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCEEEECHHHHHH
WLGTVLSSDKTIDEDTFAEIQVKAHTGVHMEQE
HHHHHHCCCCCCCCCCHHEEEEEECCCCCCCCH
>Mature Secondary Structure
MNMTAFLLFLAIVGLTLIITYFAAKRTKTTSEFYTAGGGLTGVQNGLAIAGDYMSAASFL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHCCCCEEECHHHHHHHHH
GIAGMIALYGFDGFFYSIGFLVAYLVVLYIVAEPLRNLGKYTMADMIAARFKEKKIRGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNTIAISTFYMIAQLVGAGALIKLLLGLDYTAAVLIVGVLMTIYVVFGGMIATSWVQII
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAVLLMAGTLVISIIVFSKFGFSLNTMFEQMKTATPLGADFLNPGNKYKVPLETLSLNLA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHCCCCCCEECCHHHHHHHHH
LVLGTAGLPHILIRFYTVKDAKTARTSVVSATWIIGVFYIMTVFLGFGAAAFVGFDAITA
EEEECCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADQAGNMAAPLLAKALGGDFLFAFVSAIAFATILAVVTGLVLSAASAFAHDIYSQIIRKG
HHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EATEKEQMKAARWASVAVSVLSILLAIFAQSLNVAFLVALAFAVAASANLPLIVFTVFWK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RFNASGALWGSLTGLISALVLVSMSPSVWDPAGGAIFTGDPLIPLSNPGIISIPLGFLGA
HHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCEEEECHHHHHH
WLGTVLSSDKTIDEDTFAEIQVKAHTGVHMEQE
HHHHHHCCCCCCCCCCHHEEEEEECCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377