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The map label for this gene is yukB

Identifier: 255767727

GI number: 255767727

Start: 3269914

End: 3274401

Strand: Reverse

Name: yukB

Synonym: BSU31875

Alternate gene names: 255767727

Gene position: 3274401-3269914 (Counterclockwise)

Preceding gene: 16080240

Following gene: 16080237

Centisome position: 77.67

GC content: 45.66

Gene sequence:

>4488_bases
TTGAGTCTATTATGGGTTTTTTACCAAAATAACGTTCAAAAATTAAATCTGTCTAACCTCCCGTCGTCTCATCCGGTGAC
CATAGGGCCTGATGTGAAGGATTCTGTTACGATCAGCACCATTCCATTTAATAGCGGAGTGATTTCTCTTAAAAGAAAGG
AATCCGGCGGCCAATACGAAGTTTTCCTGGGAAATGATTGTCTCGGCACGATTGAGACGGATATATCATTTACTCTCCAA
ACGGATCAGCAGGATATACGCTTGATATTGACGGGCAGTGAACCTGAGAAATCCGTTTATTTTACGGGAAATCGGGATGA
AATTGTATGTTCCTCAGAAAAAACGAATGCAGATATTTATCTGAATCCGCAAGATTTTGCATTTGCAGAACAAAGCACGT
TTTCTTTGCTCCGTGCAGGCGGCAGCTGGTCGGTCCGCCCTGAAAGCGGAACGATCTTCTTGAACGGAGAGAAAATCAAC
GCCAATACGCCGCTCAAGCCGGGGGATGAAATATTCTGGAACTTCACGCAAATGAGGGTGACGGAACAAGACCTTTTAGA
AATTGTTCATTATGCCCAGTTTGAAACAGCGTTAACAGAAACGGTCAAACCGAGTACAGAGATGCAGAAAAAATATCCGC
AGTACAGAAGAACGCCGCGGATGGTATACGATCTGCCGGATGACCGCGTTTCTTTCAGTTTTCCCTCTCAGGAGAGCGAT
CAAACCAACAGAGGGCTGTGGCTCGTCATCCTGCCTCCGCTTGTGATGCTGATCGTGATGGGCGTAGTTGCCATCATCCA
GCCGCGCGGCATATTTATACTCGTTTCTTTGGCGATGTTTATGATGACTCTCATTACCTCGACAGTGCAATATTTCCGTG
ATAAAAACCAGCGGAAAAAACGCGAGGAAAAACGGGAGCGTGTATATAAGCTTTACTTAGACAATAAGCGGAAAGAGCTT
CAGGCACTTGCTGAAAAGCAAAAGCAGGTTCTTGAATTTCACTTTCCTTCATTTGAACAAATGAAATACTTAACAAGTGA
AATCAGTGACCGGATCTGGGAAAAATCACTTGAAAGCAAGGATTATCTCCAGCTGCGGCTTGGGACGGGAACAGTTCCGT
CAAGCTATGAAATCAATATGAGTGGCGGAGACTTGGCGAATCGTGATATCGATGACCTCATGGAGAAATCGCAGCACATG
CAACGCGTCTATAAAGATATCCGTAATGCGCCGGTGACGGTCGATTTGGCAGAAGGTCCGATGGGGCTTGTCGGTAAATC
ACAAATTGTGAAAAATGAGATTCACCAGCTAATCGGACAGCTGTCGTTCTTTAACAGCTATCACGATTTGCGTTTCGTAT
TTATTTTTCATGAAGAAGAGTATAAAGACTGGGAGTGGATGAAGTGGCTTCCGCAATTTCAAATGCCCCATATTTATGCA
AAAGGATTTATTTATAATGAGCAAACCCGAGATCAGCTCCTGTCTTCACTTTACGAATTGATCAGAGAGCGTGATCTCGA
AGATGACAAAGAAAAACTGCAGTTCAAACCGCATTTTGTATTTGTCATCACGAATCAGCAGCTGATCTCTGAGCATGTCA
TTCTCGAATATTTAGAAGGGCAGCATGAGCATCTGGGCATCTCGACAATTGTCGCTGCAGAAACAAAGGAAAGCTTGTCG
GAAAACATTACAACTCTTGTCCGCTACATTAATGAGCATGAAGGCGACATTTTAATACAAAAGAAAAAAGCGGTAAGAAT
TCCGTTCCGTCTCGATCATCATCAGCGTGAGGATAACGAACGGTTTTCACGCACACTGCGGACGCTGAACCACCAGGTCG
GCATTACGAATTCCATTCCGGAAACGGTATCGTTCCTGGAGCTTTTTCATGCGAAGGAAGTAAAAGAAATCGGCATTCAG
CAAAGATGGCTGACAAGTGAATCGTCGAAGTCGCTGTCAGTGCCGATCGGCTATAAAGGGAAAGATGACATTGTGTATCT
GAACCTTCACGAAAAAGCACACGGTCCGCACGGCTTGCTTGCGGGGACAACGGGATCAGGGAAAAGTGAATTTCTCCAGA
CCTACATCTTGTCACTTGCAGTGCATTTTCATCCGCATGAAGCGGCTTTCTTACTAATTGACTATAAAGGCGGAGGAATG
GCGCAGCCGTTCCGTAACATTCCCCACCTCCTCGGCACGATCACAAATATTGAAGGAAGCAAAAACTTCAGTATGCGTGC
GCTTGCTTCCATTAAAAGCGAGCTAAAAAAAAGGCAGCGCCTGTTTGACCAGTATCAAGTCAATCACATCAATGACTATA
CAAAGCTATACAAGCAAGGGAAAGCAGAAGTGGCGATGCCTCACTTGTTCTTAATTTCTGATGAGTTTGCCGAGCTGAAA
AGCGAGGAGCCTGATTTTATCAGGGAGCTTGTCAGTGCCGCGCGTATCGGACGAAGCCTCGGCGTTCATTTGATTTTGGC
GACACAGAAGCCAGGCGGCATCATCGACGACCAGATCTGGAGTAACTCGCGCTTTAAAGTAGCGCTCAAGGTCCAGGATG
CCACCGACAGTAAAGAAATTTTGAAAAACAGCGATGCCGCAAACATTACCGTAACAGGCCGCGGCTATTTGCAGGTCGGA
AACAATGAAGTGTATGAGCTGTTCCAATCTGCATGGAGCGGGGCGCCTTACTTAGAGGAAGTCTACGGTACCGAGGATGA
AATCGCGATCGTCACAGATACGGGTCTGATCCCGCTTTCTGAGGTTGATACCGAAGATAACGCGAAAAAAGACGTTCAAA
CCGAAATCGAAGCTGTAGTTGACGAAATTGAACGCATCCAAGATGAAATGGGAATCGAGAAGCTGCCAAGCCCTTGGCTG
CCGCCGCTTGCGGAACGTATTCCGCGCACTCTTTTCCCTTCAAACGAAAAAGACCATTTCCACTTTGCGTATGTCGATGA
ACCTGATCTGCAAAGACAGGCGCCAATTGCTTATAAGATGATGGAAGATGGAAATATCGGCATCTTCGGCTCTTCGGGCT
ACGGAAAATCGATTGCAGCCGCAACGTTCCTGATGAGTTTTGCGGACGTATACACACCTGAAGAGCTTCATGTCTATATC
TTTGATTTCGGAAACGGAACGCTGCTGCCATTAGCGAAGCTCCCGCATACCGCGGATTACTTCCTGATGGACCAGTCAAG
GAAAATTGAAAAGTTCATGATTCGCATCAAAGAAGAAATTGACCGCCGTAAACGTTTGTTCCGGGAAAAAGAAATCAGCC
ACATCAAAATGTACAATGCGCTGAGCGAAGAAGAGCTTCCATTCATTTTTATCACCATTGACAACTTTGACATTGTCAAG
GATGAGATGCATGAGCTTGAATCGGAATTTGTCCAGCTTTCCAGAGACGGACAAAGCTTGGGTATCTACTTTATGCTGAC
AGCAACGCGGGTGAATGCTGTCCGCCAGTCATTGTTAAATAACTTGAAAACAAAGATTGTCCATTATCTCATGGATCAAT
CAGAAGGATATTCCATTTACGGCCGTCCGAAATTCAATCTTGAGCCGATTCCGGGACGCGTCATCATTCAAAAGGAAGAG
CTTTATTTCGCGCAAATGTTCCTGCCTGTTGACGCCGATGATGATATCGGCATGTTCAACGAGCTGAAATCAGACGTACA
GAAACTTCAAGGGCGATTTGCTTCAATGGAGCAGCCGGCACCGATTCCGATGCTGCCTGAGAGCTTGTCGACGAGAGAAT
TGTCTATCCGCTTCAAGCTGGAACGCAAGCCTTTATCTGTACCGATCGGGCTTCATGAAGAAACAGTCAGCCCAGTCTAT
TTTGATTTGGGCAAGCATAAGCACTGCCTGATTTTAGGCCAAACTCAGCGCGGGAAAACAAACGTCCTAAAAGTCATGCT
TGAACATCTGATTGATGATGAAACCGAAATGATCGGCCTGTTTGACTCGATTGACCGCGGCTTATCTCATTATGCGAAGG
AATCAGATGTTTCATATTTGGAAACGAAAGAAGATATTGAGCAGTGGATTGAAACAGCAGAAGACATTTTCAAAACAAGA
GAAGCCATGTATGTAGAAGCCGTCCGCCAAGGAGACGCACAAAATCTGCGATTCTCACAAGTCGTGCTGATGATTGACGG
GATAACGAGATTCCAGCAGACGATTGATACGAGAATACAAGATCGTCTCGCTAACTTCATGAAATCATACGCTCATCTTG
GGTTCAGCTTTATCCCGGGCGGAAACCACAGCGAATTCTCAAAAGGCTATGACTCCTTGACGACTGAGATGAAGCAAATC
CGCCACGCGATTCTGCTGATGAAAAAGTCTGAGCAAAATGTCATTCCTCTCCCGTACCAAAGACAGGAGCCTGAGATTCA
GCCGGGCTTCGGATATGTTGTGGAAAACGGGAAGGAGCAAAAAGTTCAAATTCCTTTATGTTCTGCTGAAAGGGAGAGTG
CTAGATGA

Upstream 100 bases:

>100_bases
AGAAACAGAAAAGAAAGATGAGAAAAAAGATGACAAATAACGTGAGACATGAAGCGCAGGTCATCGCATGCTGCCATTCG
GCCGTAAGGGGGTTCGCCAT

Downstream 100 bases:

>100_bases
CAGAACAACGAAAAAGCTTGATCAAGTTAATATCCGCCGTCATCATCATTTTGCTGCTGCCGGTGTTGTTTTTCCGATTT
ATCGGAGACGACCCAACGAA

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1495; Mature: 1494

Protein sequence:

>1495_residues
MSLLWVFYQNNVQKLNLSNLPSSHPVTIGPDVKDSVTISTIPFNSGVISLKRKESGGQYEVFLGNDCLGTIETDISFTLQ
TDQQDIRLILTGSEPEKSVYFTGNRDEIVCSSEKTNADIYLNPQDFAFAEQSTFSLLRAGGSWSVRPESGTIFLNGEKIN
ANTPLKPGDEIFWNFTQMRVTEQDLLEIVHYAQFETALTETVKPSTEMQKKYPQYRRTPRMVYDLPDDRVSFSFPSQESD
QTNRGLWLVILPPLVMLIVMGVVAIIQPRGIFILVSLAMFMMTLITSTVQYFRDKNQRKKREEKRERVYKLYLDNKRKEL
QALAEKQKQVLEFHFPSFEQMKYLTSEISDRIWEKSLESKDYLQLRLGTGTVPSSYEINMSGGDLANRDIDDLMEKSQHM
QRVYKDIRNAPVTVDLAEGPMGLVGKSQIVKNEIHQLIGQLSFFNSYHDLRFVFIFHEEEYKDWEWMKWLPQFQMPHIYA
KGFIYNEQTRDQLLSSLYELIRERDLEDDKEKLQFKPHFVFVITNQQLISEHVILEYLEGQHEHLGISTIVAAETKESLS
ENITTLVRYINEHEGDILIQKKKAVRIPFRLDHHQREDNERFSRTLRTLNHQVGITNSIPETVSFLELFHAKEVKEIGIQ
QRWLTSESSKSLSVPIGYKGKDDIVYLNLHEKAHGPHGLLAGTTGSGKSEFLQTYILSLAVHFHPHEAAFLLIDYKGGGM
AQPFRNIPHLLGTITNIEGSKNFSMRALASIKSELKKRQRLFDQYQVNHINDYTKLYKQGKAEVAMPHLFLISDEFAELK
SEEPDFIRELVSAARIGRSLGVHLILATQKPGGIIDDQIWSNSRFKVALKVQDATDSKEILKNSDAANITVTGRGYLQVG
NNEVYELFQSAWSGAPYLEEVYGTEDEIAIVTDTGLIPLSEVDTEDNAKKDVQTEIEAVVDEIERIQDEMGIEKLPSPWL
PPLAERIPRTLFPSNEKDHFHFAYVDEPDLQRQAPIAYKMMEDGNIGIFGSSGYGKSIAAATFLMSFADVYTPEELHVYI
FDFGNGTLLPLAKLPHTADYFLMDQSRKIEKFMIRIKEEIDRRKRLFREKEISHIKMYNALSEEELPFIFITIDNFDIVK
DEMHELESEFVQLSRDGQSLGIYFMLTATRVNAVRQSLLNNLKTKIVHYLMDQSEGYSIYGRPKFNLEPIPGRVIIQKEE
LYFAQMFLPVDADDDIGMFNELKSDVQKLQGRFASMEQPAPIPMLPESLSTRELSIRFKLERKPLSVPIGLHEETVSPVY
FDLGKHKHCLILGQTQRGKTNVLKVMLEHLIDDETEMIGLFDSIDRGLSHYAKESDVSYLETKEDIEQWIETAEDIFKTR
EAMYVEAVRQGDAQNLRFSQVVLMIDGITRFQQTIDTRIQDRLANFMKSYAHLGFSFIPGGNHSEFSKGYDSLTTEMKQI
RHAILLMKKSEQNVIPLPYQRQEPEIQPGFGYVVENGKEQKVQIPLCSAERESAR

Sequences:

>Translated_1495_residues
MSLLWVFYQNNVQKLNLSNLPSSHPVTIGPDVKDSVTISTIPFNSGVISLKRKESGGQYEVFLGNDCLGTIETDISFTLQ
TDQQDIRLILTGSEPEKSVYFTGNRDEIVCSSEKTNADIYLNPQDFAFAEQSTFSLLRAGGSWSVRPESGTIFLNGEKIN
ANTPLKPGDEIFWNFTQMRVTEQDLLEIVHYAQFETALTETVKPSTEMQKKYPQYRRTPRMVYDLPDDRVSFSFPSQESD
QTNRGLWLVILPPLVMLIVMGVVAIIQPRGIFILVSLAMFMMTLITSTVQYFRDKNQRKKREEKRERVYKLYLDNKRKEL
QALAEKQKQVLEFHFPSFEQMKYLTSEISDRIWEKSLESKDYLQLRLGTGTVPSSYEINMSGGDLANRDIDDLMEKSQHM
QRVYKDIRNAPVTVDLAEGPMGLVGKSQIVKNEIHQLIGQLSFFNSYHDLRFVFIFHEEEYKDWEWMKWLPQFQMPHIYA
KGFIYNEQTRDQLLSSLYELIRERDLEDDKEKLQFKPHFVFVITNQQLISEHVILEYLEGQHEHLGISTIVAAETKESLS
ENITTLVRYINEHEGDILIQKKKAVRIPFRLDHHQREDNERFSRTLRTLNHQVGITNSIPETVSFLELFHAKEVKEIGIQ
QRWLTSESSKSLSVPIGYKGKDDIVYLNLHEKAHGPHGLLAGTTGSGKSEFLQTYILSLAVHFHPHEAAFLLIDYKGGGM
AQPFRNIPHLLGTITNIEGSKNFSMRALASIKSELKKRQRLFDQYQVNHINDYTKLYKQGKAEVAMPHLFLISDEFAELK
SEEPDFIRELVSAARIGRSLGVHLILATQKPGGIIDDQIWSNSRFKVALKVQDATDSKEILKNSDAANITVTGRGYLQVG
NNEVYELFQSAWSGAPYLEEVYGTEDEIAIVTDTGLIPLSEVDTEDNAKKDVQTEIEAVVDEIERIQDEMGIEKLPSPWL
PPLAERIPRTLFPSNEKDHFHFAYVDEPDLQRQAPIAYKMMEDGNIGIFGSSGYGKSIAAATFLMSFADVYTPEELHVYI
FDFGNGTLLPLAKLPHTADYFLMDQSRKIEKFMIRIKEEIDRRKRLFREKEISHIKMYNALSEEELPFIFITIDNFDIVK
DEMHELESEFVQLSRDGQSLGIYFMLTATRVNAVRQSLLNNLKTKIVHYLMDQSEGYSIYGRPKFNLEPIPGRVIIQKEE
LYFAQMFLPVDADDDIGMFNELKSDVQKLQGRFASMEQPAPIPMLPESLSTRELSIRFKLERKPLSVPIGLHEETVSPVY
FDLGKHKHCLILGQTQRGKTNVLKVMLEHLIDDETEMIGLFDSIDRGLSHYAKESDVSYLETKEDIEQWIETAEDIFKTR
EAMYVEAVRQGDAQNLRFSQVVLMIDGITRFQQTIDTRIQDRLANFMKSYAHLGFSFIPGGNHSEFSKGYDSLTTEMKQI
RHAILLMKKSEQNVIPLPYQRQEPEIQPGFGYVVENGKEQKVQIPLCSAERESAR
>Mature_1494_residues
SLLWVFYQNNVQKLNLSNLPSSHPVTIGPDVKDSVTISTIPFNSGVISLKRKESGGQYEVFLGNDCLGTIETDISFTLQT
DQQDIRLILTGSEPEKSVYFTGNRDEIVCSSEKTNADIYLNPQDFAFAEQSTFSLLRAGGSWSVRPESGTIFLNGEKINA
NTPLKPGDEIFWNFTQMRVTEQDLLEIVHYAQFETALTETVKPSTEMQKKYPQYRRTPRMVYDLPDDRVSFSFPSQESDQ
TNRGLWLVILPPLVMLIVMGVVAIIQPRGIFILVSLAMFMMTLITSTVQYFRDKNQRKKREEKRERVYKLYLDNKRKELQ
ALAEKQKQVLEFHFPSFEQMKYLTSEISDRIWEKSLESKDYLQLRLGTGTVPSSYEINMSGGDLANRDIDDLMEKSQHMQ
RVYKDIRNAPVTVDLAEGPMGLVGKSQIVKNEIHQLIGQLSFFNSYHDLRFVFIFHEEEYKDWEWMKWLPQFQMPHIYAK
GFIYNEQTRDQLLSSLYELIRERDLEDDKEKLQFKPHFVFVITNQQLISEHVILEYLEGQHEHLGISTIVAAETKESLSE
NITTLVRYINEHEGDILIQKKKAVRIPFRLDHHQREDNERFSRTLRTLNHQVGITNSIPETVSFLELFHAKEVKEIGIQQ
RWLTSESSKSLSVPIGYKGKDDIVYLNLHEKAHGPHGLLAGTTGSGKSEFLQTYILSLAVHFHPHEAAFLLIDYKGGGMA
QPFRNIPHLLGTITNIEGSKNFSMRALASIKSELKKRQRLFDQYQVNHINDYTKLYKQGKAEVAMPHLFLISDEFAELKS
EEPDFIRELVSAARIGRSLGVHLILATQKPGGIIDDQIWSNSRFKVALKVQDATDSKEILKNSDAANITVTGRGYLQVGN
NEVYELFQSAWSGAPYLEEVYGTEDEIAIVTDTGLIPLSEVDTEDNAKKDVQTEIEAVVDEIERIQDEMGIEKLPSPWLP
PLAERIPRTLFPSNEKDHFHFAYVDEPDLQRQAPIAYKMMEDGNIGIFGSSGYGKSIAAATFLMSFADVYTPEELHVYIF
DFGNGTLLPLAKLPHTADYFLMDQSRKIEKFMIRIKEEIDRRKRLFREKEISHIKMYNALSEEELPFIFITIDNFDIVKD
EMHELESEFVQLSRDGQSLGIYFMLTATRVNAVRQSLLNNLKTKIVHYLMDQSEGYSIYGRPKFNLEPIPGRVIIQKEEL
YFAQMFLPVDADDDIGMFNELKSDVQKLQGRFASMEQPAPIPMLPESLSTRELSIRFKLERKPLSVPIGLHEETVSPVYF
DLGKHKHCLILGQTQRGKTNVLKVMLEHLIDDETEMIGLFDSIDRGLSHYAKESDVSYLETKEDIEQWIETAEDIFKTRE
AMYVEAVRQGDAQNLRFSQVVLMIDGITRFQQTIDTRIQDRLANFMKSYAHLGFSFIPGGNHSEFSKGYDSLTTEMKQIR
HAILLMKKSEQNVIPLPYQRQEPEIQPGFGYVVENGKEQKVQIPLCSAERESAR

Specific function: DNA Motor Protein, Which Is Both Required To Move DNA Out Of The Region Of The Septum During Cell Division And For The Septum Formation. Tracks DNA In An ATP-Dependent Manner By Generating Positive Supercoils In Front Of It And Negative Supercoils Behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 FtsK domains

Homologues:

Organism=Escherichia coli, GI1787117, Length=239, Percent_Identity=29.2887029288703, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YUKB_BACSU (C0SPA7)

Other databases:

- EMBL:   AL009126
- EMBL:   Z82015
- EMBL:   Z82015
- PIR:   D70013
- RefSeq:   NP_391066.2
- ProteinModelPortal:   C0SPA7
- EnsemblBacteria:   EBBACT00000002615
- GeneID:   936565
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31875
- GenoList:   BSU31875
- GeneTree:   EBGT00050000000196
- ProtClustDB:   CLSK2517419
- BioCyc:   BSUB:BSU31875-MONOMER
- InterPro:   IPR002543
- InterPro:   IPR022206

Pfam domain/function: PF01580 FtsK_SpoIIIE; PF12538 FtsK_SpoIIIE_N

EC number: NA

Molecular weight: Translated: 171853; Mature: 171722

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11e1d8c8)-; HASH(0x121a6bcc)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLWVFYQNNVQKLNLSNLPSSHPVTIGPDVKDSVTISTIPFNSGVISLKRKESGGQYE
CCEEEEEEECCCEEEECCCCCCCCCEEECCCCCCCEEEEEECCCCCEEEEEECCCCCEEE
VFLGNDCLGTIETDISFTLQTDQQDIRLILTGSEPEKSVYFTGNRDEIVCSSEKTNADIY
EEECCCCCEEEECCEEEEEECCCCCEEEEEECCCCCCCEEEECCCCCEEECCCCCCCEEE
LNPQDFAFAEQSTFSLLRAGGSWSVRPESGTIFLNGEKINANTPLKPGDEIFWNFTQMRV
ECCCCCCHHHHHHHHHHHCCCCEEECCCCCEEEEECCEECCCCCCCCCHHHEEEHHHEEE
TEQDLLEIVHYAQFETALTETVKPSTEMQKKYPQYRRTPRMVYDLPDDRVSFSFPSQESD
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHCCCCEEEECCCCCEEEECCCCCCC
QTNRGLWLVILPPLVMLIVMGVVAIIQPRGIFILVSLAMFMMTLITSTVQYFRDKNQRKK
CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REEKRERVYKLYLDNKRKELQALAEKQKQVLEFHFPSFEQMKYLTSEISDRIWEKSLESK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
DYLQLRLGTGTVPSSYEINMSGGDLANRDIDDLMEKSQHMQRVYKDIRNAPVTVDLAEGP
CEEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
MGLVGKSQIVKNEIHQLIGQLSFFNSYHDLRFVFIFHEEEYKDWEWMKWLPQFQMPHIYA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHCCCCCCCEEEE
KGFIYNEQTRDQLLSSLYELIRERDLEDDKEKLQFKPHFVFVITNQQLISEHVILEYLEG
CCEEECCHHHHHHHHHHHHHHHHCCCCCCHHHCEECCEEEEEEECHHHHHHHHHHHHHCC
QHEHLGISTIVAAETKESLSENITTLVRYINEHEGDILIQKKKAVRIPFRLDHHQREDNE
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCEEECCCCCCHHH
RFSRTLRTLNHQVGITNSIPETVSFLELFHAKEVKEIGIQQRWLTSESSKSLSVPIGYKG
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEECCCC
KDDIVYLNLHEKAHGPHGLLAGTTGSGKSEFLQTYILSLAVHFHPHEAAFLLIDYKGGGM
CCCEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHEECCCCEEEEEEEECCCCC
AQPFRNIPHLLGTITNIEGSKNFSMRALASIKSELKKRQRLFDQYQVNHINDYTKLYKQG
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KAEVAMPHLFLISDEFAELKSEEPDFIRELVSAARIGRSLGVHLILATQKPGGIIDDQIW
CCCEECCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHC
SNSRFKVALKVQDATDSKEILKNSDAANITVTGRGYLQVGNNEVYELFQSAWSGAPYLEE
CCCEEEEEEEEECCCCHHHHHCCCCCCEEEEECCEEEEECCHHHHHHHHHHCCCCCHHHH
VYGTEDEIAIVTDTGLIPLSEVDTEDNAKKDVQTEIEAVVDEIERIQDEMGIEKLPSPWL
HCCCCCCEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
PPLAERIPRTLFPSNEKDHFHFAYVDEPDLQRQAPIAYKMMEDGNIGIFGSSGYGKSIAA
CHHHHHCCHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHH
ATFLMSFADVYTPEELHVYIFDFGNGTLLPLAKLPHTADYFLMDQSRKIEKFMIRIKEEI
HHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHCCCCCCCEEEECCCHHHHHHHHHHHHHH
DRRKRLFREKEISHIKMYNALSEEELPFIFITIDNFDIVKDEMHELESEFVQLSRDGQSL
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCE
GIYFMLTATRVNAVRQSLLNNLKTKIVHYLMDQSEGYSIYGRPKFNLEPIPGRVIIQKEE
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEEEECC
LYFAQMFLPVDADDDIGMFNELKSDVQKLQGRFASMEQPAPIPMLPESLSTRELSIRFKL
EEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEE
ERKPLSVPIGLHEETVSPVYFDLGKHKHCLILGQTQRGKTNVLKVMLEHLIDDETEMIGL
ECCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHH
FDSIDRGLSHYAKESDVSYLETKEDIEQWIETAEDIFKTREAMYVEAVRQGDAQNLRFSQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VVLMIDGITRFQQTIDTRIQDRLANFMKSYAHLGFSFIPGGNHSEFSKGYDSLTTEMKQI
HEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHH
RHAILLMKKSEQNVIPLPYQRQEPEIQPGFGYVVENGKEQKVQIPLCSAERESAR
HHHHHHEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCH
>Mature Secondary Structure 
SLLWVFYQNNVQKLNLSNLPSSHPVTIGPDVKDSVTISTIPFNSGVISLKRKESGGQYE
CEEEEEEECCCEEEECCCCCCCCCEEECCCCCCCEEEEEECCCCCEEEEEECCCCCEEE
VFLGNDCLGTIETDISFTLQTDQQDIRLILTGSEPEKSVYFTGNRDEIVCSSEKTNADIY
EEECCCCCEEEECCEEEEEECCCCCEEEEEECCCCCCCEEEECCCCCEEECCCCCCCEEE
LNPQDFAFAEQSTFSLLRAGGSWSVRPESGTIFLNGEKINANTPLKPGDEIFWNFTQMRV
ECCCCCCHHHHHHHHHHHCCCCEEECCCCCEEEEECCEECCCCCCCCCHHHEEEHHHEEE
TEQDLLEIVHYAQFETALTETVKPSTEMQKKYPQYRRTPRMVYDLPDDRVSFSFPSQESD
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHCCCCEEEECCCCCEEEECCCCCCC
QTNRGLWLVILPPLVMLIVMGVVAIIQPRGIFILVSLAMFMMTLITSTVQYFRDKNQRKK
CCCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REEKRERVYKLYLDNKRKELQALAEKQKQVLEFHFPSFEQMKYLTSEISDRIWEKSLESK
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
DYLQLRLGTGTVPSSYEINMSGGDLANRDIDDLMEKSQHMQRVYKDIRNAPVTVDLAEGP
CEEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
MGLVGKSQIVKNEIHQLIGQLSFFNSYHDLRFVFIFHEEEYKDWEWMKWLPQFQMPHIYA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHCCCCCCCEEEE
KGFIYNEQTRDQLLSSLYELIRERDLEDDKEKLQFKPHFVFVITNQQLISEHVILEYLEG
CCEEECCHHHHHHHHHHHHHHHHCCCCCCHHHCEECCEEEEEEECHHHHHHHHHHHHHCC
QHEHLGISTIVAAETKESLSENITTLVRYINEHEGDILIQKKKAVRIPFRLDHHQREDNE
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCEEECCCCCCHHH
RFSRTLRTLNHQVGITNSIPETVSFLELFHAKEVKEIGIQQRWLTSESSKSLSVPIGYKG
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCEEEEECCCC
KDDIVYLNLHEKAHGPHGLLAGTTGSGKSEFLQTYILSLAVHFHPHEAAFLLIDYKGGGM
CCCEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHEECCCCEEEEEEEECCCCC
AQPFRNIPHLLGTITNIEGSKNFSMRALASIKSELKKRQRLFDQYQVNHINDYTKLYKQG
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KAEVAMPHLFLISDEFAELKSEEPDFIRELVSAARIGRSLGVHLILATQKPGGIIDDQIW
CCCEECCEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHC
SNSRFKVALKVQDATDSKEILKNSDAANITVTGRGYLQVGNNEVYELFQSAWSGAPYLEE
CCCEEEEEEEEECCCCHHHHHCCCCCCEEEEECCEEEEECCHHHHHHHHHHCCCCCHHHH
VYGTEDEIAIVTDTGLIPLSEVDTEDNAKKDVQTEIEAVVDEIERIQDEMGIEKLPSPWL
HCCCCCCEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCC
PPLAERIPRTLFPSNEKDHFHFAYVDEPDLQRQAPIAYKMMEDGNIGIFGSSGYGKSIAA
CHHHHHCCHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHH
ATFLMSFADVYTPEELHVYIFDFGNGTLLPLAKLPHTADYFLMDQSRKIEKFMIRIKEEI
HHHHHHHHHHCCCCCEEEEEEECCCCCEEEHHCCCCCCCEEEECCCHHHHHHHHHHHHHH
DRRKRLFREKEISHIKMYNALSEEELPFIFITIDNFDIVKDEMHELESEFVQLSRDGQSL
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCE
GIYFMLTATRVNAVRQSLLNNLKTKIVHYLMDQSEGYSIYGRPKFNLEPIPGRVIIQKEE
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEEEECC
LYFAQMFLPVDADDDIGMFNELKSDVQKLQGRFASMEQPAPIPMLPESLSTRELSIRFKL
EEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEE
ERKPLSVPIGLHEETVSPVYFDLGKHKHCLILGQTQRGKTNVLKVMLEHLIDDETEMIGL
ECCCCCCCCCCCCCCCCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHH
FDSIDRGLSHYAKESDVSYLETKEDIEQWIETAEDIFKTREAMYVEAVRQGDAQNLRFSQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
VVLMIDGITRFQQTIDTRIQDRLANFMKSYAHLGFSFIPGGNHSEFSKGYDSLTTEMKQI
HEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHHHHHHHHHHHHHH
RHAILLMKKSEQNVIPLPYQRQEPEIQPGFGYVVENGKEQKVQIPLCSAERESAR
HHHHHHEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9168598