Click here to switch to the map view.

The map label for this gene is ilvH

Identifier: 255767651

GI number: 255767651

Start: 2894733

End: 2895251

Strand: Reverse

Name: ilvH

Synonym: BSU28300

Alternate gene names: 255767651

Gene position: 2895251-2894733 (Counterclockwise)

Preceding gene: 16079883

Following gene: 16079881

Centisome position: 68.68

GC content: 42.0

Gene sequence:

>519_bases
TTGAAAAGAATTATCACATTGACTGTGGTGAACCGCTCCGGGGTGTTAAACCGGATCACCGGTCTATTCACAAAAAGGCA
TTACAACATTGAAAGCATTACAGTTGGACACACAGAAACAGCCGGCGTTTCCAGAATCACCTTCGTCGTTCATGTTGAAG
GTGAAAATGATGTTGAACAGTTAACGAAACAGCTCAACAAACAGATTGATGTGCTGAAAGTCACAGACATCACAAATCAA
TCGATTGTCCAGAGGGAGCTGGCCTTAATCAAGGTTGTCTCCGCACCTTCAACAAGAACAGAGATTAATGGAATCATAGA
ACCGTTTAGAGCCTCTGTCGTTGATGTCAGCAGAGACAGCATCGTTGTTCAGGTGACAGGTGAATCTAACAAAATTGAAG
CGCTTATTGAGTTATTAAAACCTTATGGCATTAAAGAAATCGCGAGAACAGGTACAACGGCTTTTGCGAGGGGAACCCAG
CAAAAGGCGTCATCCAATAAAACAATATCTATTGTATAA

Upstream 100 bases:

>100_bases
GAGAACCTGTTGTCATTGACGTGCGGGTTGCCAGCGAAGAAAAAGTATTCCCGATGGTGGCTCCGGGGAAAGGGCTGCAT
GAAATGGTGGGGGTGAAACC

Downstream 100 bases:

>100_bases
AACATAACAAGGGAGAGATTGAAATGGTAAAAGTATATTATAACGGTGATATCAAAGAGAACGTATTGGCTGGAAAAACA
GTAGCGGTTATCGGGTACGG

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSRITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQ
SIVQRELALIKVVSAPSTRTEINGIIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQ
QKASSNKTISIV

Sequences:

>Translated_172_residues
MKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSRITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQ
SIVQRELALIKVVSAPSTRTEINGIIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQ
QKASSNKTISIV
>Mature_172_residues
MKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSRITFVVHVEGENDVEQLTKQLNKQIDVLKVTDITNQ
SIVQRELALIKVVSAPSTRTEINGIIEPFRASVVDVSRDSIVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQ
QKASSNKTISIV

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain

Homologues:

Organism=Escherichia coli, GI1786266, Length=161, Percent_Identity=37.2670807453416, Blast_Score=110, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319837, Length=224, Percent_Identity=25, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ILVH_BACSU (P37252)

Other databases:

- EMBL:   L03181
- EMBL:   Z75208
- EMBL:   AL009126
- PIR:   E69644
- RefSeq:   NP_390708.2
- ProteinModelPortal:   P37252
- SMR:   P37252
- EnsemblBacteria:   EBBACT00000002035
- GeneID:   937477
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU28300
- NMPDR:   fig|224308.1.peg.2833
- GenoList:   BSU28300
- GeneTree:   EBGT00050000000959
- HOGENOM:   HBG335310
- PhylomeDB:   P37252
- ProtClustDB:   PRK11895
- BioCyc:   BSUB:BSU28300-MONOMER
- BRENDA:   2.2.1.6
- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912
- TIGRFAMs:   TIGR00119

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C

EC number: =2.2.1.6

Molecular weight: Translated: 18925; Mature: 18925

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSRITFVVHVEGENDVEQ
CCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHH
LTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSTRTEINGIIEPFRASVVDVSRDS
HHHHHHCCEEEEEEECCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHEEEECCCE
IVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKASSNKTISIV
EEEEEECCCCHHHHHHHHHCCCCHHHHHHCCCHHHHCCCHHHCCCCCEEEEC
>Mature Secondary Structure
MKRIITLTVVNRSGVLNRITGLFTKRHYNIESITVGHTETAGVSRITFVVHVEGENDVEQ
CCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEECCCCHHHH
LTKQLNKQIDVLKVTDITNQSIVQRELALIKVVSAPSTRTEINGIIEPFRASVVDVSRDS
HHHHHHCCEEEEEEECCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHEEEECCCE
IVVQVTGESNKIEALIELLKPYGIKEIARTGTTAFARGTQQKASSNKTISIV
EEEEEECCCCHHHHHHHHHCCCCHHHHHHCCCHHHHCCCHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377