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The map label for this gene is ilvC

Identifier: 16079881

GI number: 16079881

Start: 2893681

End: 2894709

Strand: Reverse

Name: ilvC

Synonym: BSU28290

Alternate gene names: 16079881

Gene position: 2894709-2893681 (Counterclockwise)

Preceding gene: 255767651

Following gene: 16079880

Centisome position: 68.67

GC content: 44.31

Gene sequence:

>1029_bases
ATGGTAAAAGTATATTATAACGGTGATATCAAAGAGAACGTATTGGCTGGAAAAACAGTAGCGGTTATCGGGTACGGTTC
GCAAGGCCACGCACATGCCCTGAACCTTAAAGAAAGCGGAGTAGACGTGATCGTCGGTGTTAGACAAGGAAAATCTTTCA
CTCAAGCCCAAGAAGACGGACATAAAGTATTTTCAGTAAAAGAAGCGGCAGCCCAAGCCGAAATCATCATGGTTCTGCTT
CCGGATGAGCAGCAGCAAAAAGTATACGAAGCTGAAATCAAAGATGAATTGACAGCAGGAAAATCATTAGTATTCGCTCA
TGGATTTAACGTGCATTTCCATCAAATTGTTCCTCCGGCGGATGTAGATGTATTCTTAGTGGCCCCTAAAGGCCCGGGAC
ACTTGGTAAGAAGAACATATGAGCAAGGAGCTGGCGTACCTGCATTGTTCGCAATCTATCAAGATGTGACTGGAGAAGCA
AGAGACAAAGCCCTCGCTTATGCTAAAGGAATCGGCGGCGCAAGAGCGGGCGTATTAGAAACGACATTTAAAGAAGAAAC
AGAAACAGATTTGTTCGGTGAGCAAGCAGTTCTTTGCGGCGGATTAAGCGCGCTTGTCAAAGCCGGATTTGAAACCTTAA
CTGAAGCAGGTTATCAGCCTGAACTTGCATACTTCGAGTGTCTTCATGAGCTGAAATTAATCGTAGACCTTATGTACGAA
GAAGGACTTGCAGGAATGAGATATTCAATCTCTGACACAGCACAGTGGGGAGATTTCGTATCAGGCCCTCGCGTTGTGGA
CGCCAAAGTAAAAGAATCTATGAAAGAAGTATTAAAAGATATCCAAAACGGTACATTCGCAAAAGAGTGGATCGTCGAAA
ACCAAGTAAACCGTCCTCGTTTCAACGCTATCAATGCAAGCGAGAACGAACATCAAATCGAAGTAGTGGGAAGAAAGCTT
CGTGAAATGATGCCGTTTGTGAAACAAGGCAAGAAGAAGGAAGCGGTGGTCTCCGTTGCGCAAAATTAA

Upstream 100 bases:

>100_bases
CGAGAACAGGTACAACGGCTTTTGCGAGGGGAACCCAGCAAAAGGCGTCATCCAATAAAACAATATCTATTGTATAAAAC
ATAACAAGGGAGAGATTGAA

Downstream 100 bases:

>100_bases
TTTTTTCGATACGACGCTTCGTGATGGTGAACAGTCCCCTGGAGTGAACTTGAATACACAGGAGAAACTTGCCATAGCTA
AGCAGCTCGAAAGACTCGGG

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIVGVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLL
PDEQQQKVYEAEIKDELTAGKSLVFAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEA
RDKALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
EGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDIQNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKL
REMMPFVKQGKKKEAVVSVAQN

Sequences:

>Translated_342_residues
MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIVGVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLL
PDEQQQKVYEAEIKDELTAGKSLVFAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEA
RDKALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
EGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDIQNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKL
REMMPFVKQGKKKEAVVSVAQN
>Mature_342_residues
MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIVGVRQGKSFTQAQEDGHKVFSVKEAAAQAEIIMVLL
PDEQQQKVYEAEIKDELTAGKSLVFAHGFNVHFHQIVPPADVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEA
RDKALAYAKGIGGARAGVLETTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
EGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDIQNGTFAKEWIVENQVNRPRFNAINASENEHQIEVVGRKL
REMMPFVKQGKKKEAVVSVAQN

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=287, Percent_Identity=34.1463414634146, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323387, Length=320, Percent_Identity=35.9375, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 37458; Mature: 37458

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIVGVRQGKSFTQAQEDG
CEEEEECCCCCCHHHCCCEEEEEEECCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHCC
HKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKSLVFAHGFNVHFHQIVPPA
CCEEEHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCC
DVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEARDKALAYAKGIGGARAGVLE
CCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHH
TTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDIQNGTFAKEWIVENQVNRPR
CCCCCCEEECCCCHHHCHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
FNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVSVAQN
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHEECCC
>Mature Secondary Structure
MVKVYYNGDIKENVLAGKTVAVIGYGSQGHAHALNLKESGVDVIVGVRQGKSFTQAQEDG
CEEEEECCCCCCHHHCCCEEEEEEECCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHCC
HKVFSVKEAAAQAEIIMVLLPDEQQQKVYEAEIKDELTAGKSLVFAHGFNVHFHQIVPPA
CCEEEHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCC
DVDVFLVAPKGPGHLVRRTYEQGAGVPALFAIYQDVTGEARDKALAYAKGIGGARAGVLE
CCCEEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHH
TTFKEETETDLFGEQAVLCGGLSALVKAGFETLTEAGYQPELAYFECLHELKLIVDLMYE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
EGLAGMRYSISDTAQWGDFVSGPRVVDAKVKESMKEVLKDIQNGTFAKEWIVENQVNRPR
CCCCCCEEECCCCHHHCHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCC
FNAINASENEHQIEVVGRKLREMMPFVKQGKKKEAVVSVAQN
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA