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The map label for this gene is clpX

Identifier: 255767648

GI number: 255767648

Start: 2884781

End: 2886043

Strand: Reverse

Name: clpX

Synonym: BSU28220

Alternate gene names: 255767648

Gene position: 2886043-2884781 (Counterclockwise)

Preceding gene: 16079875

Following gene: 16079873

Centisome position: 68.46

GC content: 41.65

Gene sequence:

>1263_bases
ATGTTTAAATTTAACGAGGAAAAAGGACAATTAAAATGCTCGTTCTGTGGAAAAACACAAGATCAGGTTCGTAAGCTTGT
AGCTGGACCTGGTGTATATATATGTGACGAATGTATCGAACTCTGCACTGAAATTGTAGAGGAAGAACTCGGAACAGAAG
AAGAAGTAGAATTTAAAGACGTACCAAAGCCTCAGGAAATTCGCGAAATTTTGAATGAATATGTCATCGGCCAAGATCAA
GCGAAGAAATCACTTGCTGTTGCTGTGTATAACCACTATAAGCGCATTAACTCCAACAGCAAAGTTGATGATGTTGAGCT
TTCAAAAAGTAATATTTCATTAATCGGCCCTACGGGAAGCGGTAAAACCCTTCTGGCGCAAACATTGGCTCGCATTTTAA
ATGTGCCGTTTGCGATTGCGGACGCTACATCTTTGACTGAAGCTGGATACGTGGGTGAAGATGTAGAGAATATTCTCTTG
AAGCTCATCCAAGCTGCTGATTATGATGTGGAAAAAGCCGAAAAAGGCATTATCTATATTGATGAAATCGATAAAGTGGC
TAGAAAATCTGAAAACCCGTCTATCACACGTGATGTGTCAGGTGAGGGTGTACAGCAGGCATTGCTTAAAATTCTTGAGG
GTACAGTGGCAAGCGTACCGCCTCAAGGTGGACGTAAGCATCCTCATCAAGAATTCATTCAAATTGACACAACAAATATT
TTGTTCATTTGCGGCGGAGCTTTCGATGGTATCGAACAAATCATCAAACGCCGTTTAGGCCAAAAAGTGATTGGATTCGG
TGCCGACAATAAAGCTGCTGATCTTGAGAAAGAAGATCTTCTTTCAAAAGTGCTTCCAGAAGATTTGCTCCGTTTCGGGT
TAATTCCTGAATTTATCGGACGTCTTCCGGTTATTGCAAGCCTTGAAAAGCTTGACGAAGAAGCATTGGTTGCGATCTTA
ACAAAACCGAAAAACGCTCTTGTTAAGCAATTCAAGAAAATGCTTGAGCTTGACAACGTTGAGCTTGAGTTTGAAGAAGA
AGCGCTTTCTGAAATTGCTAAAAAAGCAATTGAACGCAAGACTGGAGCACGCGGACTCCGTTCTATCATTGAAGGCATCA
TGCTTGATGTGATGTTTGAGCTGCCTTCTCGTGATGACATTGAAAAATGTGTAATCACCGGGGCAACTGTGACACACGGA
GAGCCTCCTCGCCTCTTATTAAAAGACGGCACTGAGGTAAGCCAAGATAAAACATCTGCATAA

Upstream 100 bases:

>100_bases
AAGTATGGTAAAATGCAATACATACTCGTTCGTTTCAAGAATCATTTTCTTTTGCTCTGCCGGTAAAAGAAAAAGTGAGA
CAAGATTAAGGGGTGAAAGA

Downstream 100 bases:

>100_bases
AGATAAGCACAAACCTCCTGAGTGGTAACACTCAGGAGGTTTTTTTGCATGCAACTCTTCCGGAAAAACGTTTATTCCCG
TCTTCTATGGGAGATACTAG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAIL
TKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHG
EPPRLLLKDGTEVSQDKTSA

Sequences:

>Translated_420_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAIL
TKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHG
EPPRLLLKDGTEVSQDKTSA
>Mature_420_residues
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQ
AKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILL
KLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
LFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAIL
TKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHG
EPPRLLLKDGTEVSQDKTSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=325, Percent_Identity=50.4615384615385, Blast_Score=315, Evalue=7e-86,
Organism=Escherichia coli, GI1786642, Length=409, Percent_Identity=63.5696821515892, Blast_Score=523, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=44.6601941747573, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=299, Percent_Identity=48.8294314381271, Blast_Score=285, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI71982905, Length=299, Percent_Identity=48.8294314381271, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI71988663, Length=406, Percent_Identity=39.1625615763547, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI71988660, Length=260, Percent_Identity=39.6153846153846, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=434, Percent_Identity=38.0184331797235, Blast_Score=256, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24648289, Length=300, Percent_Identity=51, Blast_Score=303, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24648291, Length=300, Percent_Identity=51, Blast_Score=303, Evalue=2e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46351; Mature: 46351

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKD
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGS
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCCCC
GKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYI
CHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCEE
LFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIG
EEEECCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHC
RLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERK
CCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
TGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQDKTSA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCEEECCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKD
CCCCCCCCCCEEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGS
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEECCCCC
GKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYI
CHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCEEEE
DEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNI
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHEEECCCEE
LFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIG
EEEECCCHHHHHHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHC
RLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERK
CCHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
TGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQDKTSA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEECCEEECCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA