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The map label for this gene is yraB

Identifier: 255767622

GI number: 255767622

Start: 2755382

End: 2755804

Strand: Reverse

Name: yraB

Synonym: BSU27000

Alternate gene names: 255767622

Gene position: 2755804-2755382 (Counterclockwise)

Preceding gene: 16079757

Following gene: 16079747

Centisome position: 65.37

GC content: 41.61

Gene sequence:

>423_bases
ATGAATATTGCTCAGGTGGCAAAGCAGTTTGGCCTGACAGCCGCAACACTCCGATATTACGAACGTGTAGGATTAATCCC
GCCTGTAAAACGAAAAGACAGCGGCATTCGCGACTATGATGAAGAAGATATCAAATGGATTGAATTCATTAAATGCATGC
GAAATGCGGGACTATCGATAGAAGCGCTAATTGAATATACAACATTATTTACCGAAGGTGACCGTACGGTAGAAGCTCGA
AAAAATATCCTGGCTGACGAACGACAGCGGCTGATAGAGAAGCGGAAAGAAATTGATGAAACAATTAAGAGATTAGACAC
AAAAATTAAAGATTATGATGGGAAATTGCGTGAAAATGAGGCAAAGCTCAAAAGCAGGCCTAAAACGGAAAGTCTTCACG
GATCAGTGGAGCAAAGAAGGTAG

Upstream 100 bases:

>100_bases
TATAAACCCAGATTCAGCAGCTAACCACTTGTTTTGAGCTTGACTTAAAGTTAACTTTAAGTGTTACCTTCACAACATAC
AGGATAGAGAGGTGAAGATC

Downstream 100 bases:

>100_bases
CATTCTTTGCGTGTGAAGAGGGCAGGTCAAAAACGAAGGATTTTGTTTCTGGCCTGTTTTCTCCATCAAGAGATCGCATA
AAAAGAGGTGGTTACGATTC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNIAQVAKQFGLTAATLRYYERVGLIPPVKRKDSGIRDYDEEDIKWIEFIKCMRNAGLSIEALIEYTTLFTEGDRTVEAR
KNILADERQRLIEKRKEIDETIKRLDTKIKDYDGKLRENEAKLKSRPKTESLHGSVEQRR

Sequences:

>Translated_140_residues
MNIAQVAKQFGLTAATLRYYERVGLIPPVKRKDSGIRDYDEEDIKWIEFIKCMRNAGLSIEALIEYTTLFTEGDRTVEAR
KNILADERQRLIEKRKEIDETIKRLDTKIKDYDGKLRENEAKLKSRPKTESLHGSVEQRR
>Mature_140_residues
MNIAQVAKQFGLTAATLRYYERVGLIPPVKRKDSGIRDYDEEDIKWIEFIKCMRNAGLSIEALIEYTTLFTEGDRTVEAR
KNILADERQRLIEKRKEIDETIKRLDTKIKDYDGKLRENEAKLKSRPKTESLHGSVEQRR

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1786695, Length=107, Percent_Identity=32.7102803738318, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADHR_BACSU (O06008)

Other databases:

- EMBL:   X92868
- EMBL:   AL009126
- PIR:   B69970
- RefSeq:   NP_390578.2
- HSSP:   P0A9G4
- ProteinModelPortal:   O06008
- SMR:   O06008
- EnsemblBacteria:   EBBACT00000001483
- GeneID:   937605
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU27000
- NMPDR:   fig|224308.1.peg.2703
- GenoList:   BSU27000
- GeneTree:   EBGT00050000001454
- HOGENOM:   HBG710951
- ProtClustDB:   CLSK887647
- BioCyc:   BSUB:BSU27000-MONOMER
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- PRINTS:   PR00040
- SMART:   SM00422

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; SSF46955 Putativ_DNA_bind

EC number: NA

Molecular weight: Translated: 16416; Mature: 16416

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00552 HTH_MERR_1; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAQVAKQFGLTAATLRYYERVGLIPPVKRKDSGIRDYDEEDIKWIEFIKCMRNAGLSI
CCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCH
EALIEYTTLFTEGDRTVEARKNILADERQRLIEKRKEIDETIKRLDTKIKDYDGKLRENE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AKLKSRPKTESLHGSVEQRR
HHHHCCCCCHHHHCCHHCCC
>Mature Secondary Structure
MNIAQVAKQFGLTAATLRYYERVGLIPPVKRKDSGIRDYDEEDIKWIEFIKCMRNAGLSI
CCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCH
EALIEYTTLFTEGDRTVEARKNILADERQRLIEKRKEIDETIKRLDTKIKDYDGKLRENE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
AKLKSRPKTESLHGSVEQRR
HHHHCCCCCHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377