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The map label for this gene is resD

Identifier: 255767498

GI number: 255767498

Start: 2417181

End: 2417903

Strand: Reverse

Name: resD

Synonym: BSU23120

Alternate gene names: 255767498

Gene position: 2417903-2417181 (Counterclockwise)

Preceding gene: 255767499

Following gene: 16079368

Centisome position: 57.36

GC content: 43.71

Gene sequence:

>723_bases
ATGGACCAAACGAACGAAACAAAAATATTAGTAGTTGATGACGAAGCCAGAATTCGCCGCCTTTTAAGAATGTATCTTGA
ACGTGAAAATTATGCTATAGATGAAGCTGAAAATGGTGATGAAGCCATTGCCAAAGGGCTTGAAGCCAATTATGACTTAA
TTTTGCTTGATCTGATGATGCCGGGGACTGATGGAATTGAAGTGTGCCGGCAAATTCGTGAAAAAAAAGCGACACCCATT
ATTATGCTGACCGCAAAAGGAGAAGAAGCAAACCGGGTGCAGGGGTTTGAAGCGGGAACAGATGATTATATTGTTAAGCC
GTTCAGCCCGAGAGAAGTCGTGCTGCGTGTAAAGGCCCTTTTGAGAAGAGCATCCCAAACCTCTTATTTCAATGCCAATA
CACCGACGAAAAATGTGCTCGTGTTTTCACATCTGTCAATAGACCATGATGCTCACCGCGTAACAGCTGATGGAACAGAA
GTGAGCCTGACGCCAAAAGAGTATGAGCTTCTATATTTCTTAGCGAAAACGCCTGACAAGGTGTATGATCGGGAAAAGCT
TCTGAAAGAAGTGTGGCAATATGAGTTTTTTGGTGATTTACGGACAGTGGACACTCACGTCAAACGCTTGAGAGAGAAGC
TGAACAAGGTATCTCCGGAAGCTGCGAAAAAAATTGTCACCGTATGGGGTGTAGGTTATAAATTTGAGGTCGGCGCTGAA
TGA

Upstream 100 bases:

>100_bases
GACTTCATTCTTATGCATAGTCCTTTGAAAGCGACACAGTTCTCAAACTTTCTCACGATTTGATAAAATGAAAGTAACAG
AAGGAAAGCAGGGGGAAAAC

Downstream 100 bases:

>100_bases
AATTTTGGAAAAGCGTAGTAGGCAAGCTGTGGTTTACGATCCTTTCACTCGTCTTGATCGTATTGTTCATTTTAACGGTT
CTTTTGCTGGAGTTTATTGA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MDQTNETKILVVDDEARIRRLLRMYLERENYAIDEAENGDEAIAKGLEANYDLILLDLMMPGTDGIEVCRQIREKKATPI
IMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKALLRRASQTSYFNANTPTKNVLVFSHLSIDHDAHRVTADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPEAAKKIVTVWGVGYKFEVGAE

Sequences:

>Translated_240_residues
MDQTNETKILVVDDEARIRRLLRMYLERENYAIDEAENGDEAIAKGLEANYDLILLDLMMPGTDGIEVCRQIREKKATPI
IMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKALLRRASQTSYFNANTPTKNVLVFSHLSIDHDAHRVTADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPEAAKKIVTVWGVGYKFEVGAE
>Mature_240_residues
MDQTNETKILVVDDEARIRRLLRMYLERENYAIDEAENGDEAIAKGLEANYDLILLDLMMPGTDGIEVCRQIREKKATPI
IMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKALLRRASQTSYFNANTPTKNVLVFSHLSIDHDAHRVTADGTE
VSLTPKEYELLYFLAKTPDKVYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPEAAKKIVTVWGVGYKFEVGAE

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=42.2413793103448, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1788394, Length=236, Percent_Identity=42.3728813559322, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=36.8421052631579, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=35.8078602620087, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786784, Length=232, Percent_Identity=37.5, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=36.8421052631579, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.9344978165939, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI2367329, Length=208, Percent_Identity=38.4615384615385, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=30.2631578947368, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=35.4700854700855, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=33.1858407079646, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=33.4782608695652, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=32.7586206896552, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=29.4372294372294, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788191, Length=108, Percent_Identity=36.1111111111111, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=132, Percent_Identity=31.8181818181818, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=103, Percent_Identity=35.9223300970874, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=198, Percent_Identity=28.7878787878788, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RESD_BACSU (P35163)

Other databases:

- EMBL:   L09228
- EMBL:   AL009126
- PIR:   G69691
- RefSeq:   NP_390193.2
- ProteinModelPortal:   P35163
- SMR:   P35163
- EnsemblBacteria:   EBBACT00000003803
- GeneID:   938960
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU23120
- NMPDR:   fig|224308.1.peg.2316
- GenoList:   BSU23120
- GeneTree:   EBGT00070000031757
- HOGENOM:   HBG753323
- PhylomeDB:   P35163
- ProtClustDB:   CLSK873069
- BioCyc:   BSUB:BSU23120-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 27516; Mature: 27516

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQTNETKILVVDDEARIRRLLRMYLERENYAIDEAENGDEAIAKGLEANYDLILLDLMM
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEC
PGTDGIEVCRQIREKKATPIIMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKAL
CCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
LRRASQTSYFNANTPTKNVLVFSHLSIDHDAHRVTADGTEVSLTPKEYELLYFLAKTPDK
HHHHHCCCEECCCCCCCEEEEEEEECCCCCCCEEECCCCEEEECCCCEEEEEEEECCCHH
VYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPEAAKKIVTVWGVGYKFEVGAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHEEHEECCCEEEEECCC
>Mature Secondary Structure
MDQTNETKILVVDDEARIRRLLRMYLERENYAIDEAENGDEAIAKGLEANYDLILLDLMM
CCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEC
PGTDGIEVCRQIREKKATPIIMLTAKGEEANRVQGFEAGTDDYIVKPFSPREVVLRVKAL
CCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
LRRASQTSYFNANTPTKNVLVFSHLSIDHDAHRVTADGTEVSLTPKEYELLYFLAKTPDK
HHHHHCCCEECCCCCCCEEEEEEEECCCCCCCEEECCCCEEEECCCCEEEEEEEECCCHH
VYDREKLLKEVWQYEFFGDLRTVDTHVKRLREKLNKVSPEAAKKIVTVWGVGYKFEVGAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHEEHEECCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783