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The map label for this gene is resE

Identifier: 16079368

GI number: 16079368

Start: 2415415

End: 2417184

Strand: Reverse

Name: resE

Synonym: BSU23110

Alternate gene names: 16079368

Gene position: 2417184-2415415 (Counterclockwise)

Preceding gene: 255767498

Following gene: 255767497

Centisome position: 57.34

GC content: 43.11

Gene sequence:

>1770_bases
ATGAAATTTTGGAAAAGCGTAGTAGGCAAGCTGTGGTTTACGATCCTTTCACTCGTCTTGATCGTATTGTTCATTTTAAC
GGTTCTTTTGCTGGAGTTTATTGAAAACTACCATGTGGAAGAAGCTGAGAATGATTTAACACAGCTTGCGAATAAAGTTG
CTGTCATCCTAGAAAATCACGAGGACCAGGCACTGGCAAGGTCAATCACTTGGGAACTCGCTGATAACTTAACAAGCATT
GCCATCATCCAGGATGAGAAGAACCACTGGTATTCTCCGAATGATAAAAATCGCCTGTCGTCTATTACGGTTGAGCAAAT
ACAGCATGACAAAGACTTAAATAAAGCTCTCAAAGACCATAAAAAAGTAAGCAAACGGACGGGACTGAGCGATACAGACA
CGGATAATGAACGCCTGATTGTAGGTGTCCCGTATGAAAAAGACGGAAAGAAAGGCATGGTCTTTTTATCCCAGTCTTTG
CTTGCCGTTAAAGATACAACAAAACATACGACCCGCTATATTTTTCTTGCCGCTGGAATTGCGATTGTGCTGACCACATT
TTTCGCATTCTTTTTATCAAGCAGGGTCACGTACCCTCTCCGAAAAATGAGAGAAGGCGCGCAGGATTTGGCGAAGGGCA
AGTTCGATACAAAAATCCCGATTTTAACTCAGGATGAAATCGGTGAACTGGCGACCGCTTTTAATCAAATGGGCCGGCAG
CTTAACTTTCATATCAATGCGCTCAATCAAGAAAAAGAGCAGCTTTCTAACATTTTGAGCAGTATGGCTGACGGGGTTAT
TACCATTAATATTGACGGTACGATTCTTGTGACCAACCCGCCGGCTGAACGTTTTCTTCAGGCTTGGTATTATGAACAGA
ACATGAATATCAAAGAAGGCGACAATCTTCCGCCTGAAGCAAAAGAGCTGTTTCAAAACGCTGTCAGCACTGAAAAAGAA
CAAATGATTGAGATGACGCTTCAAGGCAGATCATGGGTGCTTTTGATGTCGCCGCTTTATGCGGAATCGCACGTCAGAGG
AGCGGTTGCCGTACTGCGTGACATGACAGAAGAACGCCGCCTTGATAAGCTGCGGGAGGACTTTATCGCAAATGTCAGTC
ATGAGCTGAGAACACCGATCTCCATGCTTCAGGGATACAGTGAAGCAATTGTCGATGACATTGCAAGCTCTGAAGAAGAC
CGGAAAGAAATTGCCCAAATCATTTATGACGAATCGCTCCGAATGGGCCGTTTAGTTAATGATTTGCTTGATTTAGCCCG
AATGGAATCAGGCCATACAGGCTTACATTATGAAAAAATCAATGTGAATGAGTTTTTAGAAAAGATCATTCGGAAGTTTT
CCGGTGTTGCGAAAGAAAAAAATATTGCTTTAGATCATGACATTTCTCTCACAGAAGAGGAATTTATGTTTGATGAAGAC
AAGATGGAGCAGGTATTTACCAATTTGATTGATAACGCGCTGCGGCATACTTCAGCCGGCGGCAGTGTCTCCATTTCAGT
CCATTCTGTGAAGGATGGATTGAAAATTGATATCAAAGACTCCGGGTCTGGCATACCGGAAGAAGATCTGCCATTTATCT
TTGAGCGGTTTTATAAGGCAGATAAAGCGCGGACAAGGGGCAGAGCAGGAACCGGGTTAGGGCTGGCTATCGTTAAAAAT
ATCGTGGAAGCCCACAACGGATCAATTACTGTGCACAGCCGAATAGATAAAGGAACAACATTTTCTTTTTATATTCCGAC
AAAACGGTAA

Upstream 100 bases:

>100_bases
TCAAACGCTTGAGAGAGAAGCTGAACAAGGTATCTCCGGAAGCTGCGAAAAAAATTGTCACCGTATGGGGTGTAGGTTAT
AAATTTGAGGTCGGCGCTGA

Downstream 100 bases:

>100_bases
AATCGAGTCTGAATTTGCCGAAGAATCTTGTTCCATAAGAAACACCCGCTGACTGAGCGGGTGTTTTTTTAATAGCCAAC
ATTAATAAAATTTAAGGATA

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MKFWKSVVGKLWFTILSLVLIVLFILTVLLLEFIENYHVEEAENDLTQLANKVAVILENHEDQALARSITWELADNLTSI
AIIQDEKNHWYSPNDKNRLSSITVEQIQHDKDLNKALKDHKKVSKRTGLSDTDTDNERLIVGVPYEKDGKKGMVFLSQSL
LAVKDTTKHTTRYIFLAAGIAIVLTTFFAFFLSSRVTYPLRKMREGAQDLAKGKFDTKIPILTQDEIGELATAFNQMGRQ
LNFHINALNQEKEQLSNILSSMADGVITINIDGTILVTNPPAERFLQAWYYEQNMNIKEGDNLPPEAKELFQNAVSTEKE
QMIEMTLQGRSWVLLMSPLYAESHVRGAVAVLRDMTEERRLDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEED
RKEIAQIIYDESLRMGRLVNDLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFMFDED
KMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFERFYKADKARTRGRAGTGLGLAIVKN
IVEAHNGSITVHSRIDKGTTFSFYIPTKR

Sequences:

>Translated_589_residues
MKFWKSVVGKLWFTILSLVLIVLFILTVLLLEFIENYHVEEAENDLTQLANKVAVILENHEDQALARSITWELADNLTSI
AIIQDEKNHWYSPNDKNRLSSITVEQIQHDKDLNKALKDHKKVSKRTGLSDTDTDNERLIVGVPYEKDGKKGMVFLSQSL
LAVKDTTKHTTRYIFLAAGIAIVLTTFFAFFLSSRVTYPLRKMREGAQDLAKGKFDTKIPILTQDEIGELATAFNQMGRQ
LNFHINALNQEKEQLSNILSSMADGVITINIDGTILVTNPPAERFLQAWYYEQNMNIKEGDNLPPEAKELFQNAVSTEKE
QMIEMTLQGRSWVLLMSPLYAESHVRGAVAVLRDMTEERRLDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEED
RKEIAQIIYDESLRMGRLVNDLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFMFDED
KMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFERFYKADKARTRGRAGTGLGLAIVKN
IVEAHNGSITVHSRIDKGTTFSFYIPTKR
>Mature_589_residues
MKFWKSVVGKLWFTILSLVLIVLFILTVLLLEFIENYHVEEAENDLTQLANKVAVILENHEDQALARSITWELADNLTSI
AIIQDEKNHWYSPNDKNRLSSITVEQIQHDKDLNKALKDHKKVSKRTGLSDTDTDNERLIVGVPYEKDGKKGMVFLSQSL
LAVKDTTKHTTRYIFLAAGIAIVLTTFFAFFLSSRVTYPLRKMREGAQDLAKGKFDTKIPILTQDEIGELATAFNQMGRQ
LNFHINALNQEKEQLSNILSSMADGVITINIDGTILVTNPPAERFLQAWYYEQNMNIKEGDNLPPEAKELFQNAVSTEKE
QMIEMTLQGRSWVLLMSPLYAESHVRGAVAVLRDMTEERRLDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEED
RKEIAQIIYDESLRMGRLVNDLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFMFDED
KMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFERFYKADKARTRGRAGTGLGLAIVKN
IVEAHNGSITVHSRIDKGTTFSFYIPTKR

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain

Homologues:

Organism=Escherichia coli, GI1786600, Length=333, Percent_Identity=31.5315315315315, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=35.1931330472103, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=31.9148936170213, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788713, Length=361, Percent_Identity=26.8698060941828, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI48994928, Length=459, Percent_Identity=26.5795206971678, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=32.3275862068966, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=30.2222222222222, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=28.695652173913, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788549, Length=437, Percent_Identity=24.4851258581236, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=28.9915966386555, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=29.1139240506329, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=27.4336283185841, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=24.1379310344828, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788279, Length=222, Percent_Identity=29.7297297297297, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=27.7272727272727, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=28.2511210762332, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790300, Length=373, Percent_Identity=24.3967828418231, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789808, Length=252, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787374, Length=215, Percent_Identity=26.9767441860465, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789403, Length=268, Percent_Identity=24.2537313432836, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RESE_BACSU (P35164)

Other databases:

- EMBL:   L09228
- EMBL:   AL009126
- PIR:   H69691
- RefSeq:   NP_390192.1
- ProteinModelPortal:   P35164
- EnsemblBacteria:   EBBACT00000003589
- GeneID:   938965
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU23110
- NMPDR:   fig|224308.1.peg.2315
- GenoList:   BSU23110
- GeneTree:   EBGT00070000031815
- HOGENOM:   HBG334875
- OMA:   TTIFAFF
- PhylomeDB:   P35164
- ProtClustDB:   CLSK873070
- BioCyc:   BSUB:BSU23110-MONOMER
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00304
- SMART:   SM00387
- SMART:   SM00388
- SMART:   SM00091

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 66772; Mature: 66772

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN; PS50112 PAS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1093c1c4)-; HASH(0x10553da0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWKSVVGKLWFTILSLVLIVLFILTVLLLEFIENYHVEEAENDLTQLANKVAVILENH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEHCCC
EDQALARSITWELADNLTSIAIIQDEKNHWYSPNDKNRLSSITVEQIQHDKDLNKALKDH
CHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KKVSKRTGLSDTDTDNERLIVGVPYEKDGKKGMVFLSQSLLAVKDTTKHTTRYIFLAAGI
HHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHH
AIVLTTFFAFFLSSRVTYPLRKMREGAQDLAKGKFDTKIPILTQDEIGELATAFNQMGRQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCE
LNFHINALNQEKEQLSNILSSMADGVITINIDGTILVTNPPAERFLQAWYYEQNMNIKEG
EEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHHHHCCCCCCCC
DNLPPEAKELFQNAVSTEKEQMIEMTLQGRSWVLLMSPLYAESHVRGAVAVLRDMTEERR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
LDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEEDRKEIAQIIYDESLRMGRLVN
HHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFMFDED
HHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHCCHH
KMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFERFYKA
HHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
DKARTRGRAGTGLGLAIVKNIVEAHNGSITVHSRIDKGTTFSFYIPTKR
HHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCH
>Mature Secondary Structure
MKFWKSVVGKLWFTILSLVLIVLFILTVLLLEFIENYHVEEAENDLTQLANKVAVILENH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEHCCC
EDQALARSITWELADNLTSIAIIQDEKNHWYSPNDKNRLSSITVEQIQHDKDLNKALKDH
CHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KKVSKRTGLSDTDTDNERLIVGVPYEKDGKKGMVFLSQSLLAVKDTTKHTTRYIFLAAGI
HHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHCCCHHHHHHHHHHHHH
AIVLTTFFAFFLSSRVTYPLRKMREGAQDLAKGKFDTKIPILTQDEIGELATAFNQMGRQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCE
LNFHINALNQEKEQLSNILSSMADGVITINIDGTILVTNPPAERFLQAWYYEQNMNIKEG
EEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHHHHCCCCCCCC
DNLPPEAKELFQNAVSTEKEQMIEMTLQGRSWVLLMSPLYAESHVRGAVAVLRDMTEERR
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHH
LDKLREDFIANVSHELRTPISMLQGYSEAIVDDIASSEEDRKEIAQIIYDESLRMGRLVN
HHHHHHHHHHHHHHHHHCHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
DLLDLARMESGHTGLHYEKINVNEFLEKIIRKFSGVAKEKNIALDHDISLTEEEFMFDED
HHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHCCHH
KMEQVFTNLIDNALRHTSAGGSVSISVHSVKDGLKIDIKDSGSGIPEEDLPFIFERFYKA
HHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHH
DKARTRGRAGTGLGLAIVKNIVEAHNGSITVHSRIDKGTTFSFYIPTKR
HHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715