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The map label for this gene is ppsA

Identifier: 255767429

GI number: 255767429

Start: 1990272

End: 1997957

Strand: Reverse

Name: ppsA

Synonym: BSU18340

Alternate gene names: 255767429

Gene position: 1997957-1990272 (Counterclockwise)

Preceding gene: 16078896

Following gene: 16078894

Centisome position: 47.39

GC content: 46.57

Gene sequence:

>7686_bases
TTGAGCGAACATACTTATTCTTTAACCCATGCCCAAAGGAGAGTGTGGTTTACCGAACTGCTGGAGCCAGATACCAGCAT
TTGCAATCTTACAGCTTGTGTGAAATTTAAAGGCAATATTGAGCTTGATACTCTGGAGGGAGCACTGAATCATTCCATCT
CCCGCAACGACGCCATTAGATTTCAGCTGTTAGAAGGAGAAGAGCTTGAGCCTCGATTGCACCTTACTGAATATAAATAT
TATCCACTTAGAATAATTGATTTTTCAAATGTTGAAATGATAGAAATAGAGCAATGGATTCAGGATCAAGCGAGCATTCC
ATTTAAACTGTTCAACTCGCCTCTTTTTCAATTTTACCTCCTTAGAATTGACTCTCATGAAGTTTGGCTATTTGCGAAAT
TCCATCATATCATAATGGATGGAATCTCTTTAAATGTGATGGGAAATCAAATTATAGATCTTTATCAAAAAATGAAAAAG
AAAGATCCTTTACCTGATCAGCCGGAACCTTCTTACTTGAGCTACATCGAAAAAGAGAGTCAATATCTACAATCTCCACG
GTTTGCAAAGGACCGTTTATTTTGGACGCAAACCTTTGAGCACCCGTTGGAATACCACTCGTTAGCCGACCAGACGTCCT
TACAAAAACAGAGCACATCTGCATCCAGAGACACCATCATTCTTTCACCTGATCTAGAGCAAACGATTCGAATCTTCTGC
GAAGAACACAAGATCAATATCATTTCCTTATTTATGGCTTCATTTTACATATGCATCAGCCGAATCACTTCTAAAAAAGA
TCTTGCCATTGGCACCTACTATGGCAACAGAGGTTCAAAGGCTGAAAAAGAAATGCTCGGCATGTTCGTTAGTTCCCTTC
CAATCAGAATAACGGTTGATCCTGACACAGATTTTCTTTCCTTTGTCCGCACAATAGGCAGGGAACAGCTTTCTGTTATG
CGTCATCAACGGTTTCCTTATAATTTGCTTGTAAATGAATTAAGAAATGAACAGAAGGATTTACACAACCTTATCGGTAT
ATCTATGCAGTATCAGCCACTTCAGTGGCACAATGCAGATGATTTTGACTATGAAACAGCGCTTTATTTCAGCGGATACA
CCGCGAACGAACTTTCAGTTCAAATACAAGAACGGATAGACAATGGAACCATTCAATTAAATTTCGACTATCAAAATACC
TTGTTTTCTCTTGAGGATATTAAACGAATACAATCTCATCTGCTTACCATACTGGAAAACGCCCTTAAACATCCGCACAG
CTTTATAAGAGAATTAGATATGACGAATACAAGAGAAAAGCAAAAATTGTTGTATGAGTTTAACAAGACGGAAGCTGTTT
CGCCTAAAGCTTTCACCCTGCATGGGCTGTTTGAGCGACAGGCAGCTTTCACACCGGAGCGGCTGGCCATTCGCTTTTCA
GGCGGTTCGCTGACATACGCTGAGCTTGATATGTACGCCAGCCGGCTGGCTGCGCACCTTGCGGCACGCGGCGTCACAAA
CGAAAGTATCGTCGGTGTCCTGTCTGAACGCTCACCTGACATGCTGATCGCTGTCCTTGCTGTATTGAAGGCCGGCGGGG
CGTATTTGCCGCTTGATCCTGCGTATCCAAAGGAGCGGCTGAGCTACATGCTGAAAGACAGCGGGGCATCGCTCTTGCTG
ACACAGCCGGGATGCTCCGCACCAAACTTTTCTGGCGAAACGCTTGAAGTGGACATGACATCTCTTGCGAGCGAAAAAGC
AGAAAACCATGAGTTTACTCCTGCTGACGGCGGATCTCTCGCCTATGTCATCTATACATCGGGCTCTACCGGGCAGCCGA
AAGGAGTGGCCGTTGAGCACCGTCAGGCTGTTTCCTTTCTGACCGGCATGCAGCACCAGTTTCCGCTTTCGGAAGATGAC
ATTGTCATGGTGAAAACCTCTTTTTCCTTTGATGCGTCTGTGTGGCAGCTGTTTTGGTGGTCGCTTTCCGGTGCTTCGGC
GTATCTGCTTCCGCCCGGCTGGGAGAAAGACTCCGCATTGATCGTACAAGCCATTCATCAGGAAAACGTGACAACGGCTC
ATTTTATTCCGGCTATGCTGAACAGCTTTCTCGATCAAGCGGAAATCGAAAGGCTGAGTGACAGGACAAGCCTAAAGCGT
GTATTCGCCGGAGGTGAACCGCTTGCGCCGCGTACGGCAGCCCGTTTTGCTTCTGTATTGCCGCAGGTATCATTAATCCA
TGGTTACGGGCCGACAGAAGCAACGGTAGACGCGGCATTTTACGTATTGGATCCAGAACGGGACAGGGATCGTTTGCGGA
TTCCGATTGGGAAGCCCGTACCTGGTGCGCGTTTGTATGTTTTAGATCCGCATTTAGCCGTACAGCCTTCCGGTGTCGCC
GGCGAACTGTACATTGCCGGAGCGGGTGTTGCCAGAGGTTATTTGAATCGGCCGGCATTAACGGAGGAGCGTTTTCTTGA
AGACCCGTTTTACCCGGGGGAACGCATGTACAAAACCGGGGATGTGGCGCGCTGGCTCCCTGACGGGAATGTTGAATTCC
TCGGGCGCACGGATGATCAGGTAAAAATCCGCGGCTACCGGATTGAGCCGGGAGAAATTGAAGCGGCACTAAGAAGCATA
GAAGGCGTAAGAGAGGCGGCTGTTACCGTACGGACAGACAGCGGGGAGCCGGAATTATGCGCTTATGTAGAAGGGCTCCA
AAGAAACGAAGTGCGTGCACAGCTTGAGAGACTGTTGCCGGGCTACATGGTCCCAGCCTATATGATAGAGATGGAACAGT
GGCCGGTTACGCCAAGCGGAAAGCTCGACCGAAACGCCCTGCCAGCTCCTGGCGGAGCGGCAGATGCGGAGACCTACACG
GCGCCGAGAAACGTGACTGAGATGAAGCTTTCTCAGCTGTGGGAGGACGTGCTGAAAAATGGCCCTGTCGGGATTCACGA
CAACTTTTTTGACCGCGGGGGACATTCCTTAAAAGCAACGGCGCTTGTCTCACGGATCGCCAAAGAATTCGATGTACAGG
TGCCGCTAAAAGATGTGTTTGCCCATCCGACAGTAGAAGGACTGGCTACCGTTATCCGTGAAGGAACGGACAGTCCATAT
GAAGCGATTAAGCCCGCTGAAAAACAGGAAACCTATCCGGTTTCCTCTGCCCAAAAGCGGATTTATGTCCTTCAGCAGCT
GGAGGACGGAGGGACAGGCTACAATATGCCGGCTGTGTTAGAGCTCGAAGGGAAGCTCAACCCTGAAAGGATGGAGAGAG
CTTTCAAAGAGCTGATCAAGCGCCACGAGTCGCTTCGGACCTCCTTCGAACAGGACGCAGGAGGCGATCCGGTGCAGCGC
ATCCATGACGAGGTGCCGTTTACGTTACAGACTACAGTTCTCGGCGAACGAACCGAACAGGAGGCCGCAGCCGCATTTAT
CAAACCGTTTGATCTCAGCCAAGCGCCGCTGTTCCGTGCCCAAATCGTAAAGATATCAGATGAGCGGCACCTGTTGCTGG
TTGATATGCATCACATCATTTCAGACGGTGTTTCCGTCAACATTCTGATTCGGGAATTCGGCGAGCTGTACAATAATCGG
AATCTTCCGGCACTGCGCATTCAATATAAAGATTATGCCGTATGGCGAGAAGGATTCAAAACAGGAGACGCGTACAAAAC
GCAAGAGGCGTACTGGCTGAAGCAGCTCGAGGGCGAGCTGCCTGTGCTGGATCTTCCGGCTGATCATGCCCGCCCGCCGG
TGCGAAGCTTCGCGGGTGACAAGGTCTCATTTACGCTGGATCAAGAGGTTGCATCAGGCCTTCACAAGCTGGCACGTGAA
AACGGAAGCACACTGTACATGGTGCTTCTTGCGGCTTACACCGCGTTCTTGTCACGCTTAAGCGGACAGGAAGATATCAT
CGTCGGCTCGCCAATTGCCGGCCGGCCGCACAAGGATCTTGAGCCGATACTCGGCATGTTTGTGAACACGCTGGCGCTTC
GGACGCGCCCGGAGGGCGGGAAGCCATTCGTACAGTATTTGCAGGAAGTGCGTGAGACAGCATTGGAAGCCTTTGAGCAC
CAGGATTACCCGTTCGAAGAGCTTGTCGATAAGCTTGAATTGACACGAGATATGAGCCGGAACCCAGTGTTTGATGCGAT
GTTTATCCTTCAAAATGTGGAAAAACAAGACATAGATCTGAGAGAAATAAAAGTCCGGCCTGCCAATTTCGCACATCACA
TTTCCTTATTTGATATCACATTAATAGCTACGGAAATAAGTGGATCTATTTGCTGCGAAATGGAATTTAGTACAGAAGTA
TTCCTGAAAGCTACGATTGAACGCTGGGCTGATCATTTTATCGAATTTCTGCATGAGGCACTTTCAACTCCTGAAACAAG
CCTTGCACAAATAAACATACTTAGTGATAAAGAAAAACAAAAAATAGTCTTTGAATTTAACAAAACTCAAGTTGAATTTG
CTCAAAAAGATATTCCTTTTCATCGCATATTTGAAGCGAAAGCTGAAGAAAATCCAGAACATATAGCTGTTATTGATAAC
GAAACAGAGATTAGCTATCGCCTTCTAAATGAAAGAGCCAATCGTCTGGCACGAACATTGCAAAACAGAAAAGGACCGAA
GCCAACTGTGGCTGTTTTAGCCAAGCGGTCCATCGATGCAATTGTTGGAGTTCTGGCAGTGATGAAAGCTGGCGGAGTGT
ATATCCCAATCGATGCACATTATCCAAAAGCTCGTATTGAATACATTCTTCGTGATAGCGGGGCAGATATTCTTCTTTTA
CAGAGAGAGTTGAAGCATTTGATTTCGAACTCGCCTGAATCTGAGATGTCTCACATCTTCCTTGACGATGAGGGCTCTTT
TGAAGAAAGTAACTGCAACCTTAACTTATCTCCTGCTCCTGAAGAGCCGGTATATATCATTTATACGTCAGGAACGACGG
GTGCGCCTAAAGGTGTTATTGTCACCTATCAGAACTTTACTCATGCTGCTCTTGCTTGGCGTCAAATTTATGAACTGGAT
CGGAAGCCTGTCAGACTGCTTCAAATCGCGAGCTTTTCATTCGATGTCTTCTCAGGAGATTTGGCGAGAACATTGACCAA
CGGCGGGACTCTAATCGTTTGCCCAGATGAAACACGGCTGGAACCTGCTGAAATATATAAAATCATTAAATCTCAGAGAA
TCACGGTGATGGAGTCGACACCGGCTCTCATTATCCCGGTGATGGAGTATGTATACCGTAACCAGTTCAAGCTTCCTGAC
TTAGACATACTGATTCTTGGTTCCGACATGGTGAAAGCTCAAGATTTCAAAACATTGACAGATCGCTTTGGCCAAAGCAT
GCGCATCATTAATAGCTATGGTGTCACAGAGGCAACCATTGATTCGAGTTTCTATGAAACCAGTATGGGTGGAGAGTGTA
CGGGAGATAACGTACCAATCGGCAGCCCGCTGCCGAATGTACACATGTACGTACTCAGCCAGACTGATCAAATTCAGCCG
ATCGGTGTTGCCGGCGAGCTGTGCATCGGCGGGGCAGGTGTTGCGAAAGGCTATCATCATAAACCTGACTTAACGCAAAT
GAAATTTACAGAAAATCCATTTGTCTCTGGAGAAAGGCTGTACAGAACCGGTGATCGAGCATGCTGGCTTCCAAACGGAA
CGATCCGGCTTCTTGGCCGAATGGATTATCAAGTAAAGATAAATGGATACAGAATTGAAACAGAAGAAATTGAAAGTGTT
CTGCTTCAAACGGGGCTTGTCAGAGAAGCTGCTGTTGCCGTTCAGCATGATAAAAATGGACAGGCTGGTTTGGCAGCATA
TATTGTGCCTTCAGACGTCAATACGAATGCTCTCCGTGCTGCTTTAACAAAGGAACTGCCAGCGTATATGATTCCTGCAT
ATCTGATTCCTTTAGTAAACATGCCGCTGACCCTAAACGGAAAGCTGGACAGAAATGCCTTGCCGGCTCCAAATAATGTG
TTATCGCGTCCATATACCGCACCAGTTAACGACTTACAAAAAACGATGGCGTATATATGGGAAGATGTACTGAGCATGTC
ACGAGTCGGCATTCACGATTCCTTTTTTGAGCTTGGCGGAGACTCAATTAAAGCATTACAAGTGGCAGCACGTCTGGCAG
CTGAAGGCTGGAGCATGACAATACGCGACTTATTCCGTTATTCAACGATTCAGGAACTATGCGGACATATCACACCATTG
GCATCTCAAGCGGACCAGGGACCTGCGGAAGGTGAAGCTGAACTCACCCCGATTCAGCGAAGATTTTTCGGACAGGTACA
TGCTTTTCACTATCATTACAACCAGTCCGTCATGCTTTTCAGTGAAAAAGGATTCAATGCTAACGCGCTTCATCTAGCGC
TGCGTAAAATAACCGAGCATCATGATGCCATTCGCATGATTTTCCAACGTGACCAAAACGGCCATGTCATTCAGTTTAAT
CGCGGAATCAATCACAAGGATCATGAACTGTTTGGCCTTTATATTTCAGATTGGACAAAAGCATCGCTGGAAAGGGCTCA
TCTTGATGAAAAACTTGCCGCTGAGGAAACCGTCATTCAAAGCAAAATGAATGTAGAAAAAGGGCCCTTACTGCAAGCAG
GTTTGTTTAAAACGGCAGAAGGGGATCATTTGCTGATTGCACTTCATCATCTTGTGATAGATGGCGTTTCTTGGAGAATT
CTGCTTGAGGATTTAGCTGCAGCATATCAACAGGCTTTAGAAAAGAAAGAAATCCAATTACCGCCAAAAACGGATTCTTA
TTTATCCTACGCCGATGGTCTTACCCAAATAGCTGAAAGTAAACAATTGCTTTCAGAGAAAACGTATTGGCAAACGATTT
TAGACGCTCACACTGCTTTTCTTCCTAAGGACATAGAAAATGTGCCAGACAAACTCCAAATGAACAGCGACGCAGCAGCG
TTTGTACTATCCGGGGACTGGACTGAAAAATTGCTGTTTGAAACCCAGCAAGCCTATGGTACTGATGCCAACGAACTTTT
GCTTACGGCTTTAGGAATGGCGCTTTCTGAATGGACTGGGCATGACCAAATCGTGATCAGCACTGAGGGACACGGTAGAG
AAGGGCATGTGCCAAACATTGATATTTCAAGGACAGTTGGATGGTTTACCTCCATTTATCCTATTCTGCTAGACATGGGT
ATTCCCGAGCCTTTCGAGGATCAGCTCGCATACCGAATTAAGACGACAAAAGATATGCTGAGAAGAGTACCGAACAAAGG
AACTGGATACGGATTGTTAACACACATAGGAGAACTGCGGCATAAAGAGCCTGAGGTCAGCTTTAATTATCTCGGTCAAT
TTAGCGAAGAGAAGGAAGTTGAAACGTTTCAATTATCATATTACCAGCCCCGTTACGAAATAGCGGGTGAGAGAGAACGA
GAGTATGAGCTGGACATCAATGCTCTCATTACGGACGGACGGCTTCACGTAAAAGCGGTATACACCCAAGTGTTCAGCAA
ACACTCAATTGAGTGCTTTATGGATCGTTTTCACAGGCATCTTATCGAGACGATTGAGCATTGTTCGCAGAAAAAAGCAC
GCGAAAAAACATTGAGCGATTTCAGCAATAAAGAATTAACGTTGTCTGCATTATCTAGCATCGAAGATCTCGTGAAAGAT
CTTTAA

Upstream 100 bases:

>100_bases
CATATATGGATTATATAGTCATATAATTTCTTTTATTGTCATTTTTCTGCTTTTTTCTACATTTTCTTATCCTCTTATTA
TGAGAACTGGAGGGAATCCG

Downstream 100 bases:

>100_bases
CTTTTGAAAAGGTGTGTGGAATTGATGGCACAATCGGCACAAATTCAAGATATTTATCCGTTATCGCACATGCAGGAAGG
AATGCTGTTTCATTCACTAA

Product: plipastatin synthetase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Peptide synthase 1; ATP-dependent glutamate adenylase 1; GluA 1; Glutamate activase 1; ATP-dependent ornithine adenylase; OrnA; Ornithine activase

Number of amino acids: Translated: 2561; Mature: 2560

Protein sequence:

>2561_residues
MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKY
YPLRIIDFSNVEMIEIEQWIQDQASIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKK
KDPLPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDTIILSPDLEQTIRIFC
EEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVM
RHQRFPYNLLVNELRNEQKDLHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQNT
LFSLEDIKRIQSHLLTILENALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAFTLHGLFERQAAFTPERLAIRFS
GGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLL
TQPGCSAPNFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFPLSEDD
IVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKR
VFAGGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVA
GELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSI
EGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYT
APRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLATVIREGTDSPY
EAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMERAFKELIKRHESLRTSFEQDAGGDPVQR
IHDEVPFTLQTTVLGERTEQEAAAAFIKPFDLSQAPLFRAQIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNR
NLPALRIQYKDYAVWREGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLDQEVASGLHKLARE
NGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEH
QDYPFEELVDKLELTRDMSRNPVFDAMFILQNVEKQDIDLREIKVRPANFAHHISLFDITLIATEISGSICCEMEFSTEV
FLKATIERWADHFIEFLHEALSTPETSLAQINILSDKEKQKIVFEFNKTQVEFAQKDIPFHRIFEAKAEENPEHIAVIDN
ETEISYRLLNERANRLARTLQNRKGPKPTVAVLAKRSIDAIVGVLAVMKAGGVYIPIDAHYPKARIEYILRDSGADILLL
QRELKHLISNSPESEMSHIFLDDEGSFEESNCNLNLSPAPEEPVYIIYTSGTTGAPKGVIVTYQNFTHAALAWRQIYELD
RKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIYKIIKSQRITVMESTPALIIPVMEYVYRNQFKLPD
LDILILGSDMVKAQDFKTLTDRFGQSMRIINSYGVTEATIDSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQP
IGVAGELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIRLLGRMDYQVKINGYRIETEEIESV
LLQTGLVREAAVAVQHDKNGQAGLAAYIVPSDVNTNALRAALTKELPAYMIPAYLIPLVNMPLTLNGKLDRNALPAPNNV
LSRPYTAPVNDLQKTMAYIWEDVLSMSRVGIHDSFFELGGDSIKALQVAARLAAEGWSMTIRDLFRYSTIQELCGHITPL
ASQADQGPAEGEAELTPIQRRFFGQVHAFHYHYNQSVMLFSEKGFNANALHLALRKITEHHDAIRMIFQRDQNGHVIQFN
RGINHKDHELFGLYISDWTKASLERAHLDEKLAAEETVIQSKMNVEKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRI
LLEDLAAAYQQALEKKEIQLPPKTDSYLSYADGLTQIAESKQLLSEKTYWQTILDAHTAFLPKDIENVPDKLQMNSDAAA
FVLSGDWTEKLLFETQQAYGTDANELLLTALGMALSEWTGHDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMG
IPEPFEDQLAYRIKTTKDMLRRVPNKGTGYGLLTHIGELRHKEPEVSFNYLGQFSEEKEVETFQLSYYQPRYEIAGERER
EYELDINALITDGRLHVKAVYTQVFSKHSIECFMDRFHRHLIETIEHCSQKKAREKTLSDFSNKELTLSALSSIEDLVKD
L

Sequences:

>Translated_2561_residues
MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKY
YPLRIIDFSNVEMIEIEQWIQDQASIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKK
KDPLPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDTIILSPDLEQTIRIFC
EEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVM
RHQRFPYNLLVNELRNEQKDLHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQNT
LFSLEDIKRIQSHLLTILENALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAFTLHGLFERQAAFTPERLAIRFS
GGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLL
TQPGCSAPNFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFPLSEDD
IVMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKR
VFAGGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVA
GELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSI
EGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYT
APRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLATVIREGTDSPY
EAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMERAFKELIKRHESLRTSFEQDAGGDPVQR
IHDEVPFTLQTTVLGERTEQEAAAAFIKPFDLSQAPLFRAQIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNR
NLPALRIQYKDYAVWREGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLDQEVASGLHKLARE
NGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEH
QDYPFEELVDKLELTRDMSRNPVFDAMFILQNVEKQDIDLREIKVRPANFAHHISLFDITLIATEISGSICCEMEFSTEV
FLKATIERWADHFIEFLHEALSTPETSLAQINILSDKEKQKIVFEFNKTQVEFAQKDIPFHRIFEAKAEENPEHIAVIDN
ETEISYRLLNERANRLARTLQNRKGPKPTVAVLAKRSIDAIVGVLAVMKAGGVYIPIDAHYPKARIEYILRDSGADILLL
QRELKHLISNSPESEMSHIFLDDEGSFEESNCNLNLSPAPEEPVYIIYTSGTTGAPKGVIVTYQNFTHAALAWRQIYELD
RKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIYKIIKSQRITVMESTPALIIPVMEYVYRNQFKLPD
LDILILGSDMVKAQDFKTLTDRFGQSMRIINSYGVTEATIDSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQP
IGVAGELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIRLLGRMDYQVKINGYRIETEEIESV
LLQTGLVREAAVAVQHDKNGQAGLAAYIVPSDVNTNALRAALTKELPAYMIPAYLIPLVNMPLTLNGKLDRNALPAPNNV
LSRPYTAPVNDLQKTMAYIWEDVLSMSRVGIHDSFFELGGDSIKALQVAARLAAEGWSMTIRDLFRYSTIQELCGHITPL
ASQADQGPAEGEAELTPIQRRFFGQVHAFHYHYNQSVMLFSEKGFNANALHLALRKITEHHDAIRMIFQRDQNGHVIQFN
RGINHKDHELFGLYISDWTKASLERAHLDEKLAAEETVIQSKMNVEKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRI
LLEDLAAAYQQALEKKEIQLPPKTDSYLSYADGLTQIAESKQLLSEKTYWQTILDAHTAFLPKDIENVPDKLQMNSDAAA
FVLSGDWTEKLLFETQQAYGTDANELLLTALGMALSEWTGHDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMG
IPEPFEDQLAYRIKTTKDMLRRVPNKGTGYGLLTHIGELRHKEPEVSFNYLGQFSEEKEVETFQLSYYQPRYEIAGERER
EYELDINALITDGRLHVKAVYTQVFSKHSIECFMDRFHRHLIETIEHCSQKKAREKTLSDFSNKELTLSALSSIEDLVKD
L
>Mature_2560_residues
SEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKYY
PLRIIDFSNVEMIEIEQWIQDQASIPFKLFNSPLFQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKK
DPLPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDTIILSPDLEQTIRIFCE
EHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMR
HQRFPYNLLVNELRNEQKDLHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQNTL
FSLEDIKRIQSHLLTILENALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAFTLHGLFERQAAFTPERLAIRFSG
GSLTYAELDMYASRLAAHLAARGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLT
QPGCSAPNFSGETLEVDMTSLASEKAENHEFTPADGGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFPLSEDDI
VMVKTSFSFDASVWQLFWWSLSGASAYLLPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRV
FAGGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAG
ELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSIE
GVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYTA
PRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLATVIREGTDSPYE
AIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMERAFKELIKRHESLRTSFEQDAGGDPVQRI
HDEVPFTLQTTVLGERTEQEAAAAFIKPFDLSQAPLFRAQIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNRN
LPALRIQYKDYAVWREGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGDKVSFTLDQEVASGLHKLAREN
GSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQ
DYPFEELVDKLELTRDMSRNPVFDAMFILQNVEKQDIDLREIKVRPANFAHHISLFDITLIATEISGSICCEMEFSTEVF
LKATIERWADHFIEFLHEALSTPETSLAQINILSDKEKQKIVFEFNKTQVEFAQKDIPFHRIFEAKAEENPEHIAVIDNE
TEISYRLLNERANRLARTLQNRKGPKPTVAVLAKRSIDAIVGVLAVMKAGGVYIPIDAHYPKARIEYILRDSGADILLLQ
RELKHLISNSPESEMSHIFLDDEGSFEESNCNLNLSPAPEEPVYIIYTSGTTGAPKGVIVTYQNFTHAALAWRQIYELDR
KPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIYKIIKSQRITVMESTPALIIPVMEYVYRNQFKLPDL
DILILGSDMVKAQDFKTLTDRFGQSMRIINSYGVTEATIDSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQPI
GVAGELCIGGAGVAKGYHHKPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIRLLGRMDYQVKINGYRIETEEIESVL
LQTGLVREAAVAVQHDKNGQAGLAAYIVPSDVNTNALRAALTKELPAYMIPAYLIPLVNMPLTLNGKLDRNALPAPNNVL
SRPYTAPVNDLQKTMAYIWEDVLSMSRVGIHDSFFELGGDSIKALQVAARLAAEGWSMTIRDLFRYSTIQELCGHITPLA
SQADQGPAEGEAELTPIQRRFFGQVHAFHYHYNQSVMLFSEKGFNANALHLALRKITEHHDAIRMIFQRDQNGHVIQFNR
GINHKDHELFGLYISDWTKASLERAHLDEKLAAEETVIQSKMNVEKGPLLQAGLFKTAEGDHLLIALHHLVIDGVSWRIL
LEDLAAAYQQALEKKEIQLPPKTDSYLSYADGLTQIAESKQLLSEKTYWQTILDAHTAFLPKDIENVPDKLQMNSDAAAF
VLSGDWTEKLLFETQQAYGTDANELLLTALGMALSEWTGHDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMGI
PEPFEDQLAYRIKTTKDMLRRVPNKGTGYGLLTHIGELRHKEPEVSFNYLGQFSEEKEVETFQLSYYQPRYEIAGERERE
YELDINALITDGRLHVKAVYTQVFSKHSIECFMDRFHRHLIETIEHCSQKKAREKTLSDFSNKELTLSALSSIEDLVKDL

Specific function: This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Orn as part of the biosynthesis of the lipopeptide antibiotic lipastatin. The Orn residue is further epimerized to the D-isomer form. The activation sites fo

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains

Homologues:

Organism=Homo sapiens, GI45580730, Length=695, Percent_Identity=24.1726618705036, Blast_Score=122, Evalue=4e-27,
Organism=Homo sapiens, GI187761345, Length=537, Percent_Identity=23.463687150838, Blast_Score=109, Evalue=4e-23,
Organism=Homo sapiens, GI187761343, Length=537, Percent_Identity=23.463687150838, Blast_Score=109, Evalue=4e-23,
Organism=Homo sapiens, GI156151445, Length=548, Percent_Identity=23.9051094890511, Blast_Score=102, Evalue=4e-21,
Organism=Homo sapiens, GI38505220, Length=494, Percent_Identity=25.5060728744939, Blast_Score=99, Evalue=5e-20,
Organism=Homo sapiens, GI28416953, Length=554, Percent_Identity=22.7436823104693, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI42544132, Length=473, Percent_Identity=23.2558139534884, Blast_Score=90, Evalue=3e-17,
Organism=Homo sapiens, GI122937307, Length=495, Percent_Identity=24.040404040404, Blast_Score=73, Evalue=4e-12,
Organism=Homo sapiens, GI115511026, Length=494, Percent_Identity=22.4696356275304, Blast_Score=71, Evalue=2e-11,
Organism=Escherichia coli, GI1786801, Length=1084, Percent_Identity=30.6273062730627, Blast_Score=381, Evalue=1e-106,
Organism=Escherichia coli, GI145693145, Length=533, Percent_Identity=25.891181988743, Blast_Score=109, Evalue=2e-24,
Organism=Escherichia coli, GI1788107, Length=545, Percent_Identity=24.7706422018349, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI1786810, Length=541, Percent_Identity=23.1053604436229, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI221142682, Length=504, Percent_Identity=22.6190476190476, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1789201, Length=364, Percent_Identity=24.1758241758242, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1788595, Length=407, Percent_Identity=25.5528255528256, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17550940, Length=1168, Percent_Identity=22.7739726027397, Blast_Score=186, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17556356, Length=558, Percent_Identity=28.494623655914, Blast_Score=166, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71994690, Length=533, Percent_Identity=22.7016885553471, Blast_Score=112, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994703, Length=533, Percent_Identity=22.7016885553471, Blast_Score=112, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994694, Length=533, Percent_Identity=22.7016885553471, Blast_Score=112, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17560308, Length=511, Percent_Identity=23.679060665362, Blast_Score=102, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17558820, Length=493, Percent_Identity=23.9350912778905, Blast_Score=102, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71996755, Length=442, Percent_Identity=24.4343891402715, Blast_Score=99, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=502, Percent_Identity=22.1115537848606, Blast_Score=98, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17560140, Length=480, Percent_Identity=22.9166666666667, Blast_Score=95, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17531443, Length=495, Percent_Identity=22.2222222222222, Blast_Score=90, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985884, Length=302, Percent_Identity=25.4966887417219, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559526, Length=324, Percent_Identity=22.2222222222222, Blast_Score=79, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI32564420, Length=558, Percent_Identity=23.4767025089606, Blast_Score=78, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI32564422, Length=558, Percent_Identity=23.4767025089606, Blast_Score=78, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=806, Percent_Identity=24.8138957816377, Blast_Score=224, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6319699, Length=534, Percent_Identity=21.5355805243446, Blast_Score=96, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6319264, Length=560, Percent_Identity=22.3214285714286, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322182, Length=365, Percent_Identity=23.8356164383562, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648676, Length=649, Percent_Identity=27.4268104776579, Blast_Score=191, Evalue=8e-48,
Organism=Drosophila melanogaster, GI24581924, Length=513, Percent_Identity=23.9766081871345, Blast_Score=103, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355181, Length=488, Percent_Identity=23.9754098360656, Blast_Score=92, Evalue=4e-18,
Organism=Drosophila melanogaster, GI18859661, Length=440, Percent_Identity=22.9545454545455, Blast_Score=88, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24582852, Length=492, Percent_Identity=22.5609756097561, Blast_Score=87, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPSA_BACSU (P39845)

Other databases:

- EMBL:   Z34883
- EMBL:   AL009126
- PIR:   I40456
- RefSeq:   NP_389716.2
- ProteinModelPortal:   P39845
- EnsemblBacteria:   EBBACT00000002521
- GeneID:   939983
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU18340
- NMPDR:   fig|224308.1.peg.1838
- GenoList:   BSU18340
- GeneTree:   EBGT00070000031957
- HOGENOM:   HBG547964
- ProtClustDB:   CLSK887367
- BioCyc:   BSUB:BSU18340-MONOMER
- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR006162
- Gene3D:   G3DSA:1.10.1200.10
- TIGRFAMs:   TIGR01733
- TIGRFAMs:   TIGR01720

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; SSF47336 ACP_like

EC number: 2.7.7.- [C]

Molecular weight: Translated: 289188; Mature: 289057

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50075 ACP_DOMAIN; PS00455 AMP_BINDING; PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGALNHSISRNDAIR
CCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCEEEEHHHHHHHCCCCCCCCEE
FQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIPFKLFNSPLFQFYL
EEEECCCCCCCCEEEEEEEEEEEEEEECCCCEEEHHHHHHHHHCCCCHHHHCCHHEEEEE
LRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPDQPEPSYLSYIEKES
EEECCCCEEEEEEHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
QYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDTIILSPDLEQTIRIFC
HHHCCCCCHHHHEEHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHH
EEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKEMLGMFVSSLPIRITVD
HHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEC
PDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQYQPLQWHNAD
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
DFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQNTLFSLEDIKRIQSHLLTILEN
CCCCCEEEEECCCCCCHHHEEEHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHH
ALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAFTLHGLFERQAAFTPERLAIRFS
HHHCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCCCCEEEEEC
GGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDP
CCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
AYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLEVDMTSLASEKAENHEFTPADGGSL
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCE
AYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWW
EEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
SLSGASAYLLPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKR
HCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFAGGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPV
HHCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCEEECCCCCC
PGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTG
CCCEEEEECCCEEECCCCCCEEEEEECCHHHHHHCCCCCCCHHHHHCCCCCCCCCEECCC
DVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELC
CCEEECCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHH
AYVEGLQRNEVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
APRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
AHPTVEGLATVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVL
CCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
ELEGKLNPERMERAFKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEQ
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEECCCCHHH
EAAAAFIKPFDLSQAPLFRAQIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNR
HHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHHHCCCEEEEHHHHHHHHHCCC
NLPALRIQYKDYAVWREGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGD
CCCEEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCHHHHCCC
KVSFTLDQEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDL
EEEEEECHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHH
EPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLELTRDMSR
HHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
NPVFDAMFILQNVEKQDIDLREIKVRPANFAHHISLFDITLIATEISGSICCEMEFSTEV
CCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEEEECCCCEEEEEECCCHH
FLKATIERWADHFIEFLHEALSTPETSLAQINILSDKEKQKIVFEFNKTQVEFAQKDIPF
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEECCHHHHHHHHCCCH
HRIFEAKAEENPEHIAVIDNETEISYRLLNERANRLARTLQNRKGPKPTVAVLAKRSIDA
HHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IVGVLAVMKAGGVYIPIDAHYPKARIEYILRDSGADILLLQRELKHLISNSPESEMSHIF
HHHHHHHHHCCCEEEEECCCCCHHHHHEEEECCCCCEEEHHHHHHHHHCCCCCCCCCEEE
LDDEGSFEESNCNLNLSPAPEEPVYIIYTSGTTGAPKGVIVTYQNFTHAALAWRQIYELD
ECCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHC
RKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIYKIIKSQRITVMEST
CCCEEHHEEHHCCCHHHCCHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCEEEEECC
PALIIPVMEYVYRNQFKLPDLDILILGSDMVKAQDFKTLTDRFGQSMRIINSYGVTEATI
CCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHH
DSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQPIGVAGELCIGGAGVAKGYHH
CCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCHHCCCCCC
KPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIRLLGRMDYQVKINGYRIETEEIESV
CCCCCEEEECCCCCCCCCHHEECCCCEEECCCCCEEEEEECCEEEEECCEEECHHHHHHH
LLQTGLVREAAVAVQHDKNGQAGLAAYIVPSDVNTNALRAALTKELPAYMIPAYLIPLVN
HHHHCCHHHHHHEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHC
MPLTLNGKLDRNALPAPNNVLSRPYTAPVNDLQKTMAYIWEDVLSMSRVGIHDSFFELGG
CCEEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
DSIKALQVAARLAAEGWSMTIRDLFRYSTIQELCGHITPLASQADQGPAEGEAELTPIQR
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHH
RFFGQVHAFHYHYNQSVMLFSEKGFNANALHLALRKITEHHDAIRMIFQRDQNGHVIQFN
HHHHHHEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
RGINHKDHELFGLYISDWTKASLERAHLDEKLAAEETVIQSKMNVEKGPLLQAGLFKTAE
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCC
GDHLLIALHHLVIDGVSWRILLEDLAAAYQQALEKKEIQLPPKTDSYLSYADGLTQIAES
CCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
KQLLSEKTYWQTILDAHTAFLPKDIENVPDKLQMNSDAAAFVLSGDWTEKLLFETQQAYG
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCCCCCEEEEEECCCHHHHHHHHHHHHC
TDANELLLTALGMALSEWTGHDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMG
CCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
IPEPFEDQLAYRIKTTKDMLRRVPNKGTGYGLLTHIGELRHKEPEVSFNYLGQFSEEKEV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCC
ETFQLSYYQPRYEIAGEREREYELDINALITDGRLHVKAVYTQVFSKHSIECFMDRFHRH
EEEEEEEECCCHHCCCCCCCEEEEEEEEEEECCCEEHHHHHHHHHHCCCHHHHHHHHHHH
LIETIEHCSQKKAREKTLSDFSNKELTLSALSSIEDLVKDL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGALNHSISRNDAIR
CCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCEEEEHHHHHHHCCCCCCCCEE
FQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIPFKLFNSPLFQFYL
EEEECCCCCCCCEEEEEEEEEEEEEEECCCCEEEHHHHHHHHHCCCCHHHHCCHHEEEEE
LRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPDQPEPSYLSYIEKES
EEECCCCEEEEEEHHHHHHCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
QYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDTIILSPDLEQTIRIFC
HHHCCCCCHHHHEEHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHH
EEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKEMLGMFVSSLPIRITVD
HHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEC
PDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQYQPLQWHNAD
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
DFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQNTLFSLEDIKRIQSHLLTILEN
CCCCCEEEEECCCCCCHHHEEEHHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHHHHHHH
ALKHPHSFIRELDMTNTREKQKLLYEFNKTEAVSPKAFTLHGLFERQAAFTPERLAIRFS
HHHCHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCCCCEEEEEC
GGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDP
CCEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCC
AYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLEVDMTSLASEKAENHEFTPADGGSL
CCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCE
AYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFPLSEDDIVMVKTSFSFDASVWQLFWW
EEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
SLSGASAYLLPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKR
HCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFAGGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPV
HHCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCEEEEEEEEECCCCCCCCEEECCCCCC
PGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTG
CCCEEEEECCCEEECCCCCCEEEEEECCHHHHHHCCCCCCCHHHHHCCCCCCCCCEECCC
DVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELC
CCEEECCCCCEEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHH
AYVEGLQRNEVRAQLERLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHEEHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
APRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHH
AHPTVEGLATVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVL
CCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
ELEGKLNPERMERAFKELIKRHESLRTSFEQDAGGDPVQRIHDEVPFTLQTTVLGERTEQ
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEECCCCHHH
EAAAAFIKPFDLSQAPLFRAQIVKISDERHLLLVDMHHIISDGVSVNILIREFGELYNNR
HHHHHHHCCCCCCCCCCCEEEEEEECCCCEEEEEEHHHHHHCCCEEEEHHHHHHHHHCCC
NLPALRIQYKDYAVWREGFKTGDAYKTQEAYWLKQLEGELPVLDLPADHARPPVRSFAGD
CCCEEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCHHHHCCC
KVSFTLDQEVASGLHKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDL
EEEEEECHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHH
EPILGMFVNTLALRTRPEGGKPFVQYLQEVRETALEAFEHQDYPFEELVDKLELTRDMSR
HHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
NPVFDAMFILQNVEKQDIDLREIKVRPANFAHHISLFDITLIATEISGSICCEMEFSTEV
CCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEEEECCCCEEEEEECCCHH
FLKATIERWADHFIEFLHEALSTPETSLAQINILSDKEKQKIVFEFNKTQVEFAQKDIPF
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEECCHHHHHHHHCCCH
HRIFEAKAEENPEHIAVIDNETEISYRLLNERANRLARTLQNRKGPKPTVAVLAKRSIDA
HHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
IVGVLAVMKAGGVYIPIDAHYPKARIEYILRDSGADILLLQRELKHLISNSPESEMSHIF
HHHHHHHHHCCCEEEEECCCCCHHHHHEEEECCCCCEEEHHHHHHHHHCCCCCCCCCEEE
LDDEGSFEESNCNLNLSPAPEEPVYIIYTSGTTGAPKGVIVTYQNFTHAALAWRQIYELD
ECCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHC
RKPVRLLQIASFSFDVFSGDLARTLTNGGTLIVCPDETRLEPAEIYKIIKSQRITVMEST
CCCEEHHEEHHCCCHHHCCHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCEEEEECC
PALIIPVMEYVYRNQFKLPDLDILILGSDMVKAQDFKTLTDRFGQSMRIINSYGVTEATI
CCHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHH
DSSFYETSMGGECTGDNVPIGSPLPNVHMYVLSQTDQIQPIGVAGELCIGGAGVAKGYHH
CCHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCHHCCCCCC
KPDLTQMKFTENPFVSGERLYRTGDRACWLPNGTIRLLGRMDYQVKINGYRIETEEIESV
CCCCCEEEECCCCCCCCCHHEECCCCEEECCCCCEEEEEECCEEEEECCEEECHHHHHHH
LLQTGLVREAAVAVQHDKNGQAGLAAYIVPSDVNTNALRAALTKELPAYMIPAYLIPLVN
HHHHCCHHHHHHEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHC
MPLTLNGKLDRNALPAPNNVLSRPYTAPVNDLQKTMAYIWEDVLSMSRVGIHDSFFELGG
CCEEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
DSIKALQVAARLAAEGWSMTIRDLFRYSTIQELCGHITPLASQADQGPAEGEAELTPIQR
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCHHHH
RFFGQVHAFHYHYNQSVMLFSEKGFNANALHLALRKITEHHDAIRMIFQRDQNGHVIQFN
HHHHHHEEEEEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
RGINHKDHELFGLYISDWTKASLERAHLDEKLAAEETVIQSKMNVEKGPLLQAGLFKTAE
CCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCC
GDHLLIALHHLVIDGVSWRILLEDLAAAYQQALEKKEIQLPPKTDSYLSYADGLTQIAES
CCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
KQLLSEKTYWQTILDAHTAFLPKDIENVPDKLQMNSDAAAFVLSGDWTEKLLFETQQAYG
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHCCCCCCEEEEEECCCHHHHHHHHHHHHC
TDANELLLTALGMALSEWTGHDQIVISTEGHGREGHVPNIDISRTVGWFTSIYPILLDMG
CCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
IPEPFEDQLAYRIKTTKDMLRRVPNKGTGYGLLTHIGELRHKEPEVSFNYLGQFSEEKEV
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCC
ETFQLSYYQPRYEIAGEREREYELDINALITDGRLHVKAVYTQVFSKHSIECFMDRFHRH
EEEEEEEECCCHHCCCCCCCEEEEEEEEEEECCCEEHHHHHHHHHHCCCHHHHHHHHHHH
LIETIEHCSQKKAREKTLSDFSNKELTLSALSSIEDLVKDL
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7711903; 9384377; 10471562