Click here to switch to the map view.

The map label for this gene is flhA

Identifier: 255767372

GI number: 255767372

Start: 1707714

End: 1709747

Strand: Direct

Name: flhA

Synonym: BSU16390

Alternate gene names: 255767372

Gene position: 1707714-1709747 (Clockwise)

Preceding gene: 16078701

Following gene: 16078703

Centisome position: 40.51

GC content: 43.85

Gene sequence:

>2034_bases
ATGTCAACAAGAGATTTATCCGTTTTAATAAGTGTTGTCCTCATTGTGGCGATGCTGGTGATTCCATTTCCTCCATGGCT
GTTAAGTATTTTGATCATTATTAATATTTCTCTTGCGTTGATCGTGCTTCTCACCACAATGAATATGCAGGAAGCGCTTC
AGTTTTCGATTTTTCCGTCACTGTTGCTGCTTTTGACCCTATTTCGTTTGGGCTTGAACGTCTCAACTACCCGTTCAATT
CTTTCACACGGTGAGGGAGGTAAAGTCGTCGAGACTTTCGGAAATTTCGTTGTCGGCGGAAATGTATTAGTTGGACTCGT
TGTATTTATCATCCTTATTATTATTCAGTTTATCGTCATTACAAAAGGTGCTGAACGTGTTTCCGAGGTTGCAGCAAGGT
TTACGCTGGACGCAATGCCGGGGAAGCAGATGAGTATTGATGCTGATTTAAACGCAGGGATGATTACCGAACAGGAAGCG
AAGCATCGCCGCGAAAAAGTGGCAAGAGAAGCAGACTTTTATGGAGCAATGGACGGTGCCAGTAAATTTGTAAAAGGTGA
CGCCATTGCCGGAATCATCATTGTGATGATCAATATTATTTTCGGAATCGTGATCGGAATGCTTCAGCAGGGCATGTCCA
TTCAAGAAGCTGCTTCACACTTTACGATGCTGACTGTAGGGGATGGAATTGTTTCGCAAATCCCGGCACTGTTAATTTCT
ACGGCTACGGGTATTGTGGTCACAAGAGCTGCATCTGAAGGAAACTTAGGGCATGACATTACAGGCCAGCTGTTTGCGTA
TCCAAAGCTTTTATACGTCGCAGCAGCTACGATCATGCTTTTAGGTATTTTCACTCCGATCGGCATCCTTCTGACGGGGC
CGCTTGCGGGATTGCTTGCTTTTGGCGCATATACACTATCTAAATCAGGTAAGGAAAAAGAAGAAGTGGATGAGATTCTT
GAGGAAGAGGCTGAGGTGGACGAGCTTAAAAGCCCTGAAAGTGTTGTTCAGCTTCTGCATATAGATCCGATAGAATTTGA
GTTTGGATATGGCCTGATACCGCTTGCTGATGCCAATCAAGGCGGTGATTTATTAGACCGAATTGTTATGATACGCCGTC
AGTTGGCTTTGGAACTCGGGCTTGTCATTCCTGTCGTGCGAATCAGAGATAATATAGCGTTGCAGCCTAATGAATACCGA
TTGAAAATTAAAGGAAACGAAGTAGCAAAAGGCGAGCTGTTGCTTGATCATTATTTAGCGATGTCGCCTACTCCTGAGGA
CGATCTCATTGAAGGGATTGAAACAGTGGAGCCTTCATTCGGACTGCCGGCTAAATGGATTAGCGAAGCGGTAAAGGATG
AAGCCGACATGCTTGGTTATACAGTAGTTGATCCTGCATCAGTCGTTTCAACGCATATTACGGAGAAAATTAAGCAGCAT
GCCCACGAATTGATCGGAAGGCAGGAGACAAAACAGCTGATCGATCACTTGAAAGAATCGTATCCAGTCCTGGTTGAAGA
GGTTACGCCGAATCCATTGTCTGTCGGTGATATTCAGAAAGTGCTTGCTAAGCTTTTAAAAGAAAAAGTTTCAATTCGAA
ACTTAGTAACGATTTTTGAAACACTTGCTGACTATGGGAAATTAACAACAGATTCTGATCTCTTGACAGAGTATACAAGA
CAAGCGCTTGCTAAACAAATTACAGCCCAGTTTGCCAAAGAAAATGAAGTGTTGAAGGTTGTTACTTGTTCCGGCCGTGT
AGAAAAAGCAATAGCAGACGGTGTGCAGCAGACGGAACACGGGAACTATTTATCACTTGAACCAGATATTTCAGAAAGTA
TAGTGCGCTCTGTCGCCAAAGAAGCTGAACAGCTCTCATTACGTCAGGAAACCGCGATTCTTCTTTGCTCGCCGCCTGTC
AGAATGTATGTGAAGCAGCTACTGGAACGGTACTTCCCTGATCTTCCGGTACTCTCTTATAACGAACTTGAGGCGAATGT
TGAGGTACAAAGCATTGGAGTGGTGGATATTTAA

Upstream 100 bases:

>100_bases
AAGAATTTTTTAAAGTTTTAGCAGAAATTCTGGCTTACGTATATAAAACAAAACAAAAAGTATATTGAATTTTTCGATTT
AAAAGGAGAGAAAAAACAGC

Downstream 100 bases:

>100_bases
TGAAAATAAAAAAATTTACTGCTGCTTCAATGCAAGAAGCGGCACTTCTCATCAGAAAAGAGTTAGGTAATGAAGCGGTC
ATATTAAATTCGAAAAAAAT

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MSTRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLLTTMNMQEALQFSIFPSLLLLLTLFRLGLNVSTTRSI
LSHGEGGKVVETFGNFVVGGNVLVGLVVFIILIIIQFIVITKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEA
KHRREKVAREADFYGAMDGASKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAASHFTMLTVGDGIVSQIPALLIS
TATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAATIMLLGIFTPIGILLTGPLAGLLAFGAYTLSKSGKEKEEVDEIL
EEEAEVDELKSPESVVQLLHIDPIEFEFGYGLIPLADANQGGDLLDRIVMIRRQLALELGLVIPVVRIRDNIALQPNEYR
LKIKGNEVAKGELLLDHYLAMSPTPEDDLIEGIETVEPSFGLPAKWISEAVKDEADMLGYTVVDPASVVSTHITEKIKQH
AHELIGRQETKQLIDHLKESYPVLVEEVTPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFETLADYGKLTTDSDLLTEYTR
QALAKQITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEHGNYLSLEPDISESIVRSVAKEAEQLSLRQETAILLCSPPV
RMYVKQLLERYFPDLPVLSYNELEANVEVQSIGVVDI

Sequences:

>Translated_677_residues
MSTRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLLTTMNMQEALQFSIFPSLLLLLTLFRLGLNVSTTRSI
LSHGEGGKVVETFGNFVVGGNVLVGLVVFIILIIIQFIVITKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEA
KHRREKVAREADFYGAMDGASKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAASHFTMLTVGDGIVSQIPALLIS
TATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAATIMLLGIFTPIGILLTGPLAGLLAFGAYTLSKSGKEKEEVDEIL
EEEAEVDELKSPESVVQLLHIDPIEFEFGYGLIPLADANQGGDLLDRIVMIRRQLALELGLVIPVVRIRDNIALQPNEYR
LKIKGNEVAKGELLLDHYLAMSPTPEDDLIEGIETVEPSFGLPAKWISEAVKDEADMLGYTVVDPASVVSTHITEKIKQH
AHELIGRQETKQLIDHLKESYPVLVEEVTPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFETLADYGKLTTDSDLLTEYTR
QALAKQITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEHGNYLSLEPDISESIVRSVAKEAEQLSLRQETAILLCSPPV
RMYVKQLLERYFPDLPVLSYNELEANVEVQSIGVVDI
>Mature_676_residues
STRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLLTTMNMQEALQFSIFPSLLLLLTLFRLGLNVSTTRSIL
SHGEGGKVVETFGNFVVGGNVLVGLVVFIILIIIQFIVITKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEAK
HRREKVAREADFYGAMDGASKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAASHFTMLTVGDGIVSQIPALLIST
ATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAATIMLLGIFTPIGILLTGPLAGLLAFGAYTLSKSGKEKEEVDEILE
EEAEVDELKSPESVVQLLHIDPIEFEFGYGLIPLADANQGGDLLDRIVMIRRQLALELGLVIPVVRIRDNIALQPNEYRL
KIKGNEVAKGELLLDHYLAMSPTPEDDLIEGIETVEPSFGLPAKWISEAVKDEADMLGYTVVDPASVVSTHITEKIKQHA
HELIGRQETKQLIDHLKESYPVLVEEVTPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFETLADYGKLTTDSDLLTEYTRQ
ALAKQITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEHGNYLSLEPDISESIVRSVAKEAEQLSLRQETAILLCSPPVR
MYVKQLLERYFPDLPVLSYNELEANVEVQSIGVVDI

Specific function: Involved in the export of flagellum proteins

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family

Homologues:

Organism=Escherichia coli, GI1788187, Length=678, Percent_Identity=44.5427728613569, Blast_Score=514, Evalue=1e-147,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLHA_BACSU (P35620)

Other databases:

- EMBL:   X63698
- EMBL:   AL009126
- PIR:   S33664
- RefSeq:   NP_389521.2
- PDB:   3MIX
- PDBsum:   3MIX
- ProteinModelPortal:   P35620
- SMR:   P35620
- EnsemblBacteria:   EBBACT00000003944
- GeneID:   940029
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU16390
- NMPDR:   fig|224308.1.peg.1642
- GenoList:   BSU16390
- GeneTree:   EBGT00050000001614
- HOGENOM:   HBG595253
- ProtClustDB:   PRK06012
- BioCyc:   BSUB:BSU16390-MONOMER
- GO:   GO:0019861
- InterPro:   IPR006301
- InterPro:   IPR001712
- PRINTS:   PR00949
- TIGRFAMs:   TIGR01398

Pfam domain/function: PF00771 FHIPEP

EC number: NA

Molecular weight: Translated: 73978; Mature: 73847

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xee1af80)-; HASH(0xf27c1c8)-; HASH(0xcc29418)-; HASH(0xf374d4c)-; HASH(0xb7dce54)-; HASH(0xedad61c)-; HASH(0xf256f00)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLLTTMNMQEALQFSIFPS
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLLLLTLFRLGLNVSTTRSILSHGEGGKVVETFGNFVVGGNVLVGLVVFIILIIIQFIVI
HHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHH
TKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEAKHRREKVAREADFYGAMDGA
CCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
SKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAASHFTMLTVGDGIVSQIPALLIS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEECCHHHHHHHHHHHH
TATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAATIMLLGIFTPIGILLTGPLAGLLA
HHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGAYTLSKSGKEKEEVDEILEEEAEVDELKSPESVVQLLHIDPIEFEFGYGLIPLADANQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCEEEECCCCC
GGDLLDRIVMIRRQLALELGLVIPVVRIRDNIALQPNEYRLKIKGNEVAKGELLLDHYLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCHHHHHHHHHH
MSPTPEDDLIEGIETVEPSFGLPAKWISEAVKDEADMLGYTVVDPASVVSTHITEKIKQH
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHH
AHELIGRQETKQLIDHLKESYPVLVEEVTPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFE
HHHHHCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLADYGKLTTDSDLLTEYTRQALAKQITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEH
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCC
GNYLSLEPDISESIVRSVAKEAEQLSLRQETAILLCSPPVRMYVKQLLERYFPDLPVLSY
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHCCCCCCEEC
NELEANVEVQSIGVVDI
CCCCCCEEEEEECCCCH
>Mature Secondary Structure 
STRDLSVLISVVLIVAMLVIPFPPWLLSILIIINISLALIVLLTTMNMQEALQFSIFPS
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LLLLLTLFRLGLNVSTTRSILSHGEGGKVVETFGNFVVGGNVLVGLVVFIILIIIQFIVI
HHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHH
TKGAERVSEVAARFTLDAMPGKQMSIDADLNAGMITEQEAKHRREKVAREADFYGAMDGA
CCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHH
SKFVKGDAIAGIIIVMINIIFGIVIGMLQQGMSIQEAASHFTMLTVGDGIVSQIPALLIS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEEEEEECCHHHHHHHHHHHH
TATGIVVTRAASEGNLGHDITGQLFAYPKLLYVAAATIMLLGIFTPIGILLTGPLAGLLA
HHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGAYTLSKSGKEKEEVDEILEEEAEVDELKSPESVVQLLHIDPIEFEFGYGLIPLADANQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCEEEECCCCC
GGDLLDRIVMIRRQLALELGLVIPVVRIRDNIALQPNEYRLKIKGNEVAKGELLLDHYLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCHHHHHHHHHH
MSPTPEDDLIEGIETVEPSFGLPAKWISEAVKDEADMLGYTVVDPASVVSTHITEKIKQH
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHH
AHELIGRQETKQLIDHLKESYPVLVEEVTPNPLSVGDIQKVLAKLLKEKVSIRNLVTIFE
HHHHHCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLADYGKLTTDSDLLTEYTRQALAKQITAQFAKENEVLKVVTCSGRVEKAIADGVQQTEH
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCC
GNYLSLEPDISESIVRSVAKEAEQLSLRQETAILLCSPPVRMYVKQLLERYFPDLPVLSY
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHCCCCCCEEC
NELEANVEVQSIGVVDI
CCCCCCEEEEEECCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8097015; 9384377