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The map label for this gene is spoVD

Identifier: 255767347

GI number: 255767347

Start: 1584214

End: 1586154

Strand: Direct

Name: spoVD

Synonym: BSU15170

Alternate gene names: 255767347

Gene position: 1584214-1586154 (Clockwise)

Preceding gene: 255767346

Following gene: 16078582

Centisome position: 37.58

GC content: 45.85

Gene sequence:

>1941_bases
TTGCGCGTCTCGAATGTAACGGTTAGAAAACGTTTATTATTTGTTTTGCTTTTTGGCGTGATCGTGTTTCTGATCATTGA
TACAAGGCTGGGGTATGTTCAGTTTGTGATGGGCGAAAAACTGACTTCGCTAGCGAAAGATTCCTGGAGCCGGAACTTGC
CGTTTGAGCCGGAGAGAGGCGAGATTCTGGATCGGAATGGTGTGAAGCTCGCAACAAATAAAAGTGCGCCGACCGTATTC
GTCGTGCCGCGCCAAGTTCAGAATCCGATGAAAACGAGCAAGCAGCTTGCGGCGGTGCTCAATATGTCAGAAGAAAAAGT
ATATAAACATGTGACAAAAAAAGCGTCAATCGAAAAGATCACTCCTGAAGGGAGAAAAATTTCAAATGAGAAGGCGAAAG
AAATCAAAGCGCTTGATTTAAAAGGTGTGTATGTTGCGGAGGACAGTATCCGTCATTACCCGTTCGGCAGCTTTTTATCT
CATGTGCTTGGATTTGCAGGAATTGACAACCAAGGGCTCCTTGGACTTGAAGCCTATTACGACGATGATTTAAAAGGGGA
AAAAGGTTCTGTTAAGTTTTATACAGATGCCAAGGGGAAGAAGATGCCTGATGAAGCGGATGACTATACGCCGCCTAAGG
ATGGGCTTGATATGAAGCTGACAGTTGATTCAAAGGTTCAGACGATAATGGAAAGAGAGCTTGATAACGCTGAGGCCAAA
TATCATCCGGACGGCATGATTGCCGTAGCCATGAATCCGAAAAACGGAGAAATTTTGGGGATGTCTAGCAGGCCTGACTT
CGACCCTGCTGATTACCAATCTGTTGATCCGTCCGTCTACAATCGAAATCTGCCAGTATGGAGCACGTATGAACCGGGAT
CTACCTTTAAAATTATTACACTTGCAGCAGCCCTTGAAGAGCAAAAAGTAAATTTGAAACGGGATCAATTTTATGATAAA
GGGCATGCTGAAGTGGACGGAGCGAGACTGCGGTGCTGGAAAAGAGGCGGGCACGGGCTGCAGACGTATCTGGAAGTTGT
GCAGAACTCCTGCAACCCGGGGTTTGTTGAATTAGGCGAGCGCTTAGGAAAGGAAAAGCTTTTCAAATATATCAAAGACT
TTGGTTTTGGACAAAAAACGGGGATTGATCTCCAAGGCGAGGGAACAGGCATCTTATTCCCGCTTGAGAGAGTGGGCCCG
GTGGAGCAAGCAACTACGGCTTTCGGACAGGGAGTATCCGTCACGCCGATTCAGCAGGTTGCAGCAGTATCCGCCGCTGT
AAACGGAGGAACGCTCTATACACCTTATATTGCAAAGGAATGGATCGATCCTGTTACGAAGAAAACGGTCAAAAAACAAT
CACCAATCGCAAAGAAACAAGTCATTTCTGAGGAAACATCCAAACAAATCCGCTATGCTCTAGAAAGCGTCGTCGCAGAA
GGAACCGGCCGCAATGCATTTGTAGAAGGATATCGTGTCGGAGGAAAAACGGGAACTGCACAAAAGGTTAAAGATGGAAA
ATATCTTGAAAACAACCATATTGTATCATTTATCGGTTTCGCGCCAGCAGATGATCCGAGTCTAGTCGTCTACGTTGCGG
TGGATAACCCGAAAGGCACGATTCAGTTTGGCGGAACGGTGGCAGCGCCTATTGTCGGAAATATTATGAGAGACAGTCTG
CCGGAACTTGGTGTGAAGCCCCGGAAAAATCAAATCGAGAAAAAATACCAATGGAACGACACAAAAACAATAGAAGTTCC
GAATGTTGTAGGGATGTCTGTCTCAGATCTTGAGTCACTATTGGTGAATCTCAATGTGGATGCTTCCGGGAAAGGGAGCA
AAATCGTTAAACAATCGCCAGCTGCCGGAACGAAAGTAAAAGAAGGCTCAAAGATACGCGTGTATTTGACTGAAGAAGAT
GAAAAGGAGGCAGCCGATTGA

Upstream 100 bases:

>100_bases
ATGCAGGCTTTCTTTTTTTATGCCTTCAGAGGAGCATCGTTCTACCTGTCCAAATTCAGGCATAAAATGAAACAAGCCTA
AATAAGGAGTGAACGGTCTC

Downstream 100 bases:

>100_bases
TTCGGGCTGCCTATTCTTTTATTGCAGAAAAAATGCTGATATCTTTCAAGATTAGCTGGATGTATCCTTTTATTTACGCT
AAAATATGAACTGTATGCTT

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MRVSNVTVRKRLLFVLLFGVIVFLIIDTRLGYVQFVMGEKLTSLAKDSWSRNLPFEPERGEILDRNGVKLATNKSAPTVF
VVPRQVQNPMKTSKQLAAVLNMSEEKVYKHVTKKASIEKITPEGRKISNEKAKEIKALDLKGVYVAEDSIRHYPFGSFLS
HVLGFAGIDNQGLLGLEAYYDDDLKGEKGSVKFYTDAKGKKMPDEADDYTPPKDGLDMKLTVDSKVQTIMERELDNAEAK
YHPDGMIAVAMNPKNGEILGMSSRPDFDPADYQSVDPSVYNRNLPVWSTYEPGSTFKIITLAAALEEQKVNLKRDQFYDK
GHAEVDGARLRCWKRGGHGLQTYLEVVQNSCNPGFVELGERLGKEKLFKYIKDFGFGQKTGIDLQGEGTGILFPLERVGP
VEQATTAFGQGVSVTPIQQVAAVSAAVNGGTLYTPYIAKEWIDPVTKKTVKKQSPIAKKQVISEETSKQIRYALESVVAE
GTGRNAFVEGYRVGGKTGTAQKVKDGKYLENNHIVSFIGFAPADDPSLVVYVAVDNPKGTIQFGGTVAAPIVGNIMRDSL
PELGVKPRKNQIEKKYQWNDTKTIEVPNVVGMSVSDLESLLVNLNVDASGKGSKIVKQSPAAGTKVKEGSKIRVYLTEED
EKEAAD

Sequences:

>Translated_646_residues
MRVSNVTVRKRLLFVLLFGVIVFLIIDTRLGYVQFVMGEKLTSLAKDSWSRNLPFEPERGEILDRNGVKLATNKSAPTVF
VVPRQVQNPMKTSKQLAAVLNMSEEKVYKHVTKKASIEKITPEGRKISNEKAKEIKALDLKGVYVAEDSIRHYPFGSFLS
HVLGFAGIDNQGLLGLEAYYDDDLKGEKGSVKFYTDAKGKKMPDEADDYTPPKDGLDMKLTVDSKVQTIMERELDNAEAK
YHPDGMIAVAMNPKNGEILGMSSRPDFDPADYQSVDPSVYNRNLPVWSTYEPGSTFKIITLAAALEEQKVNLKRDQFYDK
GHAEVDGARLRCWKRGGHGLQTYLEVVQNSCNPGFVELGERLGKEKLFKYIKDFGFGQKTGIDLQGEGTGILFPLERVGP
VEQATTAFGQGVSVTPIQQVAAVSAAVNGGTLYTPYIAKEWIDPVTKKTVKKQSPIAKKQVISEETSKQIRYALESVVAE
GTGRNAFVEGYRVGGKTGTAQKVKDGKYLENNHIVSFIGFAPADDPSLVVYVAVDNPKGTIQFGGTVAAPIVGNIMRDSL
PELGVKPRKNQIEKKYQWNDTKTIEVPNVVGMSVSDLESLLVNLNVDASGKGSKIVKQSPAAGTKVKEGSKIRVYLTEED
EKEAAD
>Mature_646_residues
MRVSNVTVRKRLLFVLLFGVIVFLIIDTRLGYVQFVMGEKLTSLAKDSWSRNLPFEPERGEILDRNGVKLATNKSAPTVF
VVPRQVQNPMKTSKQLAAVLNMSEEKVYKHVTKKASIEKITPEGRKISNEKAKEIKALDLKGVYVAEDSIRHYPFGSFLS
HVLGFAGIDNQGLLGLEAYYDDDLKGEKGSVKFYTDAKGKKMPDEADDYTPPKDGLDMKLTVDSKVQTIMERELDNAEAK
YHPDGMIAVAMNPKNGEILGMSSRPDFDPADYQSVDPSVYNRNLPVWSTYEPGSTFKIITLAAALEEQKVNLKRDQFYDK
GHAEVDGARLRCWKRGGHGLQTYLEVVQNSCNPGFVELGERLGKEKLFKYIKDFGFGQKTGIDLQGEGTGILFPLERVGP
VEQATTAFGQGVSVTPIQQVAAVSAAVNGGTLYTPYIAKEWIDPVTKKTVKKQSPIAKKQVISEETSKQIRYALESVVAE
GTGRNAFVEGYRVGGKTGTAQKVKDGKYLENNHIVSFIGFAPADDPSLVVYVAVDNPKGTIQFGGTVAAPIVGNIMRDSL
PELGVKPRKNQIEKKYQWNDTKTIEVPNVVGMSVSDLESLLVNLNVDASGKGSKIVKQSPAAGTKVKEGSKIRVYLTEED
EKEAAD

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain

Homologues:

Organism=Escherichia coli, GI1786272, Length=567, Percent_Identity=29.1005291005291, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1786854, Length=632, Percent_Identity=25.1582278481013, Blast_Score=166, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SP5D_BACSU (Q03524)

Other databases:

- EMBL:   Z25865
- EMBL:   AL009126
- EMBL:   L09703
- EMBL:   Z15056
- EMBL:   Z68230
- PIR:   S49570
- RefSeq:   NP_389400.2
- ProteinModelPortal:   Q03524
- SMR:   Q03524
- EnsemblBacteria:   EBBACT00000004075
- GeneID:   936661
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU15170
- NMPDR:   fig|224308.1.peg.1519
- GenoList:   BSU15170
- GeneTree:   EBGT00070000031885
- HOGENOM:   HBG712588
- ProtClustDB:   CLSK873350
- BioCyc:   BSUB:BSU15170-MONOMER
- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927
- SMART:   SM00740
- TIGRFAMs:   TIGR02214

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase; SSF56519 PBP_dimer; SSF56601 PBP_transp_fold

EC number: NA

Molecular weight: Translated: 71119; Mature: 71119

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS51178 PASTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSNVTVRKRLLFVLLFGVIVFLIIDTRLGYVQFVMGEKLTSLAKDSWSRNLPFEPERG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EILDRNGVKLATNKSAPTVFVVPRQVQNPMKTSKQLAAVLNMSEEKVYKHVTKKASIEKI
CEECCCCEEEEECCCCCEEEEECHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHC
TPEGRKISNEKAKEIKALDLKGVYVAEDSIRHYPFGSFLSHVLGFAGIDNQGLLGLEAYY
CCCCCCCCCHHHHHHHEEECCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEC
DDDLKGEKGSVKFYTDAKGKKMPDEADDYTPPKDGLDMKLTVDSKVQTIMERELDNAEAK
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCE
YHPDGMIAVAMNPKNGEILGMSSRPDFDPADYQSVDPSVYNRNLPVWSTYEPGSTFKIIT
ECCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEE
LAAALEEQKVNLKRDQFYDKGHAEVDGARLRCWKRGGHGLQTYLEVVQNSCNPGFVELGE
HHHHHHHHHCCCCHHHHCCCCCCCCCCHHEEEECCCCCHHHHHHHHHHCCCCCCHHHHHH
RLGKEKLFKYIKDFGFGQKTGIDLQGEGTGILFPLERVGPVEQATTAFGQGVSVTPIQQV
HHCHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEHHHCCCHHHHHHHHCCCCCCCHHHHH
AAVSAAVNGGTLYTPYIAKEWIDPVTKKTVKKQSPIAKKQVISEETSKQIRYALESVVAE
HHHHHCCCCCEEECCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GTGRNAFVEGYRVGGKTGTAQKVKDGKYLENNHIVSFIGFAPADDPSLVVYVAVDNPKGT
CCCCCEEEEEEEECCCCCCCHHCCCCCEECCCCEEEEEECCCCCCCCEEEEEEECCCCCE
IQFGGTVAAPIVGNIMRDSLPELGVKPRKNQIEKKYQWNDTKTIEVPNVVGMSVSDLESL
EEECCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHH
LVNLNVDASGKGSKIVKQSPAAGTKVKEGSKIRVYLTEEDEKEAAD
HEEECCCCCCCCCEEEECCCCCCCEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MRVSNVTVRKRLLFVLLFGVIVFLIIDTRLGYVQFVMGEKLTSLAKDSWSRNLPFEPERG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
EILDRNGVKLATNKSAPTVFVVPRQVQNPMKTSKQLAAVLNMSEEKVYKHVTKKASIEKI
CEECCCCEEEEECCCCCEEEEECHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHC
TPEGRKISNEKAKEIKALDLKGVYVAEDSIRHYPFGSFLSHVLGFAGIDNQGLLGLEAYY
CCCCCCCCCHHHHHHHEEECCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEC
DDDLKGEKGSVKFYTDAKGKKMPDEADDYTPPKDGLDMKLTVDSKVQTIMERELDNAEAK
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHCCCCCCE
YHPDGMIAVAMNPKNGEILGMSSRPDFDPADYQSVDPSVYNRNLPVWSTYEPGSTFKIIT
ECCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCCEEECCCCCCCEEEEE
LAAALEEQKVNLKRDQFYDKGHAEVDGARLRCWKRGGHGLQTYLEVVQNSCNPGFVELGE
HHHHHHHHHCCCCHHHHCCCCCCCCCCHHEEEECCCCCHHHHHHHHHHCCCCCCHHHHHH
RLGKEKLFKYIKDFGFGQKTGIDLQGEGTGILFPLERVGPVEQATTAFGQGVSVTPIQQV
HHCHHHHHHHHHHCCCCCCCCEEECCCCCEEEEEHHHCCCHHHHHHHHCCCCCCCHHHHH
AAVSAAVNGGTLYTPYIAKEWIDPVTKKTVKKQSPIAKKQVISEETSKQIRYALESVVAE
HHHHHCCCCCEEECCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GTGRNAFVEGYRVGGKTGTAQKVKDGKYLENNHIVSFIGFAPADDPSLVVYVAVDNPKGT
CCCCCEEEEEEEECCCCCCCHHCCCCCEECCCCEEEEEECCCCCCCCEEEEEEECCCCCE
IQFGGTVAAPIVGNIMRDSLPELGVKPRKNQIEKKYQWNDTKTIEVPNVVGMSVSDLESL
EEECCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHH
LVNLNVDASGKGSKIVKQSPAAGTKVKEGSKIRVYLTEEDEKEAAD
HEEECCCCCCCCCEEEECCCCCCCEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954