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The map label for this gene is adeC

Identifier: 255767335

GI number: 255767335

Start: 1521351

End: 1523084

Strand: Direct

Name: adeC

Synonym: BSU14520

Alternate gene names: 255767335

Gene position: 1521351-1523084 (Clockwise)

Preceding gene: 16078515

Following gene: 16078519

Centisome position: 36.09

GC content: 43.31

Gene sequence:

>1734_bases
TTGAATAAAGAAGCGCTAGTCAATAGGCTGAATGCTTCAGCCAAAAGACAAAAAGCTGATATCGTCATTAAAAACGGAAA
AATCATGGACGTATATAATCAAGAATGGATATATGAAGATATTGCGATTACAGATGGAGTTATTGTAGGCCTCGGTGAGT
ATGAAGGCGAAAATATCATTGATGCAGAGGGACAAATGATTGTTCCGGGTTTTATTGATGGACATGTACATATTGAGTCG
TCAATGGTTACACCGATTGAGTTCGCTAAAGCAGTGTTGCCTCATGGCGTGACGACGGTTGTTACAGATCCGCATGAGAT
CGCGAATGTGTCTGGTGAAAAAGGGATTGAGTTTATGCTTGAACAAGCTCGGCATACACCGCTGAATATCCATTTTATGC
TTCCTTCCAGTGTGCCTGCCGCAAGTTTTGAGCGATCAGGCGCAATTCTCAAAGCTGCCGATCTCAAGCCTTTTTATGAA
GAAGAAGAAGTATTAGGGCTGGCTGAAGTTATGGATTATGTGTCGGTTCAGCAGGCTGAAAAAGACATGGTTCAGAAACT
GCTTGATGCCCGTGTGGCAGGAAAAAGGATAGACGGTCATTTAGCTGGTTTATCAACAGACCTCATTAACATTTACAGAA
CCGCATTTGTCTTAAACGACCATGAAGTAACATCGAAGGAAGAAGCCCTTGATCGTATCAGAAGGGGCATGTATGTCATG
ATGCGTGAAGGATCAGTCGCCAAAAACACGCTCAATGTGCTGCCGGCGGTGAATGAAAAGAACGCACGCCGGTTCTTTTT
CTGTACGGATGATAAGCATGTGGATGATTTATTGTCAGAGGGAAGTGTAAACCATCAGGTGAAAATGGCGATTCAAGCCG
GACTTAATCCGTTTTTAGCCTATCAGCTAGGAAGCCTCAATGCAGCCGAATGCTACGGATTAGATACAAAGGGAGCGATT
GCCCCGGGTTTTGACGCTGATTTGCTTTTTGTATCTGATCTGGAAAATGTCACTGTCACAATGACGATGGTAAAAGGGCA
GACTGTTGCTGAAGACAGCAAAGCGGTCTATCAGGATCATGCTTCAACTGCAGCACCAGATCAGGCACTGCTTGATTCTG
TTAAGCTTGCTGCTCCTCTTAACAAACAGGATTTTCATATGCCAATCGATTCAGAGCAGCAGATCAATGTCATTCAAATC
ATACCAAATCAGCTTGAAACACGATTAGTACAAGTTCCGGCTCCTGTTGCCCGCGAATTTGAGCCTGACACTGAGCTTGA
TTTGTTAAAGATTGCAGTTGTCGAGCGGCATAAAGGATTAAAAGAAACCGGACTTGGTGTTGTGAAAGGTTTTGGATTCA
AGAGCGGAGCGATTGCCACAACCATTTCACACGACTCCCATAATATTATTGCCGTCGGAACGAATGATGAGGATATCGCG
GCGGCAGTTAATAAGCTGCAGGAAATTGGCGGAGGATTAACAATTATAAAAAATGGGGAAGAGCTCCATTCAGTACCGCT
GCCGATTGCAGGGTTATTATCCGACCAATCTGCAGAGCAAGTGAATCAAAGCTTGCTGACGCTTCATGATAAATTGTCGT
TAATCGGTTTCACAGGCGGATTTAATCCATTTTTGACATTGTCGTTTTTAGCGTTGCCTGTCATTCCTGATATTAAAATG
ACGACTACGGGATTATTCGATGTAAAATCATTTCAACACATATCACTGCAATAA

Upstream 100 bases:

>100_bases
ACTTTAATGAACTGAGCGTCAATTTCTTAAAATTTCATTGACTAAGCACAGGCGTTCCGATAGCATATTGTACCATATAA
TAAAAAAAGGAGGGGCCTAT

Downstream 100 bases:

>100_bases
AAAGAGGCACTCCCTTAGGGAGTGCCTCTTTTTTTAAACCTCCATAATGATCGGCAGGATCATTGGACGGCGCTTTGTTT
TTTCGTACAAGAAAGGTGCA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNKEALVNRLNASAKRQKADIVIKNGKIMDVYNQEWIYEDIAITDGVIVGLGEYEGENIIDAEGQMIVPGFIDGHVHIES
SMVTPIEFAKAVLPHGVTTVVTDPHEIANVSGEKGIEFMLEQARHTPLNIHFMLPSSVPAASFERSGAILKAADLKPFYE
EEEVLGLAEVMDYVSVQQAEKDMVQKLLDARVAGKRIDGHLAGLSTDLINIYRTAFVLNDHEVTSKEEALDRIRRGMYVM
MREGSVAKNTLNVLPAVNEKNARRFFFCTDDKHVDDLLSEGSVNHQVKMAIQAGLNPFLAYQLGSLNAAECYGLDTKGAI
APGFDADLLFVSDLENVTVTMTMVKGQTVAEDSKAVYQDHASTAAPDQALLDSVKLAAPLNKQDFHMPIDSEQQINVIQI
IPNQLETRLVQVPAPVAREFEPDTELDLLKIAVVERHKGLKETGLGVVKGFGFKSGAIATTISHDSHNIIAVGTNDEDIA
AAVNKLQEIGGGLTIIKNGEELHSVPLPIAGLLSDQSAEQVNQSLLTLHDKLSLIGFTGGFNPFLTLSFLALPVIPDIKM
TTTGLFDVKSFQHISLQ

Sequences:

>Translated_577_residues
MNKEALVNRLNASAKRQKADIVIKNGKIMDVYNQEWIYEDIAITDGVIVGLGEYEGENIIDAEGQMIVPGFIDGHVHIES
SMVTPIEFAKAVLPHGVTTVVTDPHEIANVSGEKGIEFMLEQARHTPLNIHFMLPSSVPAASFERSGAILKAADLKPFYE
EEEVLGLAEVMDYVSVQQAEKDMVQKLLDARVAGKRIDGHLAGLSTDLINIYRTAFVLNDHEVTSKEEALDRIRRGMYVM
MREGSVAKNTLNVLPAVNEKNARRFFFCTDDKHVDDLLSEGSVNHQVKMAIQAGLNPFLAYQLGSLNAAECYGLDTKGAI
APGFDADLLFVSDLENVTVTMTMVKGQTVAEDSKAVYQDHASTAAPDQALLDSVKLAAPLNKQDFHMPIDSEQQINVIQI
IPNQLETRLVQVPAPVAREFEPDTELDLLKIAVVERHKGLKETGLGVVKGFGFKSGAIATTISHDSHNIIAVGTNDEDIA
AAVNKLQEIGGGLTIIKNGEELHSVPLPIAGLLSDQSAEQVNQSLLTLHDKLSLIGFTGGFNPFLTLSFLALPVIPDIKM
TTTGLFDVKSFQHISLQ
>Mature_577_residues
MNKEALVNRLNASAKRQKADIVIKNGKIMDVYNQEWIYEDIAITDGVIVGLGEYEGENIIDAEGQMIVPGFIDGHVHIES
SMVTPIEFAKAVLPHGVTTVVTDPHEIANVSGEKGIEFMLEQARHTPLNIHFMLPSSVPAASFERSGAILKAADLKPFYE
EEEVLGLAEVMDYVSVQQAEKDMVQKLLDARVAGKRIDGHLAGLSTDLINIYRTAFVLNDHEVTSKEEALDRIRRGMYVM
MREGSVAKNTLNVLPAVNEKNARRFFFCTDDKHVDDLLSEGSVNHQVKMAIQAGLNPFLAYQLGSLNAAECYGLDTKGAI
APGFDADLLFVSDLENVTVTMTMVKGQTVAEDSKAVYQDHASTAAPDQALLDSVKLAAPLNKQDFHMPIDSEQQINVIQI
IPNQLETRLVQVPAPVAREFEPDTELDLLKIAVVERHKGLKETGLGVVKGFGFKSGAIATTISHDSHNIIAVGTNDEDIA
AAVNKLQEIGGGLTIIKNGEELHSVPLPIAGLLSDQSAEQVNQSLLTLHDKLSLIGFTGGFNPFLTLSFLALPVIPDIKM
TTTGLFDVKSFQHISLQ

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=568, Percent_Identity=36.0915492957746, Blast_Score=328, Evalue=5e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_BACSU (P39761)

Other databases:

- EMBL:   D37799
- EMBL:   X83795
- EMBL:   AF012285
- EMBL:   AL009126
- PIR:   B69583
- RefSeq:   NP_389335.2
- ProteinModelPortal:   P39761
- SMR:   P39761
- EnsemblBacteria:   EBBACT00000003184
- GeneID:   939477
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14520
- NMPDR:   fig|224308.1.peg.1454
- GenoList:   BSU14520
- GeneTree:   EBGT00070000032083
- HOGENOM:   HBG725357
- ProtClustDB:   CLSK887242
- BioCyc:   BSUB:BSU14520-MONOMER
- BRENDA:   3.5.4.2
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 62893; Mature: 62893

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKEALVNRLNASAKRQKADIVIKNGKIMDVYNQEWIYEDIAITDGVIVGLGEYEGENII
CCHHHHHHHHCCHHHHCCCCEEEECCEEEEECCCCCEEEEEEECCCEEEECCCCCCCEEE
DAEGQMIVPGFIDGHVHIESSMVTPIEFAKAVLPHGVTTVVTDPHEIANVSGEKGIEFML
CCCCCEEECEEECCEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHCCCCCCHHHHHH
EQARHTPLNIHFMLPSSVPAASFERSGAILKAADLKPFYEEEEVLGLAEVMDYVSVQQAE
HHHCCCCEEEEEECCCCCCCCCHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KDMVQKLLDARVAGKRIDGHLAGLSTDLINIYRTAFVLNDHEVTSKEEALDRIRRGMYVM
HHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCEEEE
MREGSVAKNTLNVLPAVNEKNARRFFFCTDDKHVDDLLSEGSVNHQVKMAIQAGLNPFLA
EECCCCCCCHHHHCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCEEEEEHHHCCCCEEE
YQLGSLNAAECYGLDTKGAIAPGFDADLLFVSDLENVTVTMTMVKGQTVAEDSKAVYQDH
EECCCCCCHHEECCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHC
ASTAAPDQALLDSVKLAAPLNKQDFHMPIDSEQQINVIQIIPNQLETRLVQVPAPVAREF
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHEEEECCCCHHHCC
EPDTELDLLKIAVVERHKGLKETGLGVVKGFGFKSGAIATTISHDSHNIIAVGTNDEDIA
CCCCCHHHHHHHHHHHHCCCHHHCCHHEECCCCCCCCEEEEEECCCCCEEEECCCCHHHH
AAVNKLQEIGGGLTIIKNGEELHSVPLPIAGLLSDQSAEQVNQSLLTLHDKLSLIGFTGG
HHHHHHHHHCCCEEEEECCCHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCC
FNPFLTLSFLALPVIPDIKMTTTGLFDVKSFQHISLQ
CCHHHHHHHHHHHCCCCCEEEECCEEECCCCCCCCCC
>Mature Secondary Structure
MNKEALVNRLNASAKRQKADIVIKNGKIMDVYNQEWIYEDIAITDGVIVGLGEYEGENII
CCHHHHHHHHCCHHHHCCCCEEEECCEEEEECCCCCEEEEEEECCCEEEECCCCCCCEEE
DAEGQMIVPGFIDGHVHIESSMVTPIEFAKAVLPHGVTTVVTDPHEIANVSGEKGIEFML
CCCCCEEECEEECCEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHCCCCCCHHHHHH
EQARHTPLNIHFMLPSSVPAASFERSGAILKAADLKPFYEEEEVLGLAEVMDYVSVQQAE
HHHCCCCEEEEEECCCCCCCCCHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KDMVQKLLDARVAGKRIDGHLAGLSTDLINIYRTAFVLNDHEVTSKEEALDRIRRGMYVM
HHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHEEEECCCCCCHHHHHHHHHCCEEEE
MREGSVAKNTLNVLPAVNEKNARRFFFCTDDKHVDDLLSEGSVNHQVKMAIQAGLNPFLA
EECCCCCCCHHHHCCCCCCCCCCEEEEECCCCHHHHHHHCCCCCCEEEEEHHHCCCCEEE
YQLGSLNAAECYGLDTKGAIAPGFDADLLFVSDLENVTVTMTMVKGQTVAEDSKAVYQDH
EECCCCCCHHEECCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHC
ASTAAPDQALLDSVKLAAPLNKQDFHMPIDSEQQINVIQIIPNQLETRLVQVPAPVAREF
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCHHHHEEEECCCCHHHCC
EPDTELDLLKIAVVERHKGLKETGLGVVKGFGFKSGAIATTISHDSHNIIAVGTNDEDIA
CCCCCHHHHHHHHHHHHCCCHHHCCHHEECCCCCCCCEEEEEECCCCCEEEECCCCHHHH
AAVNKLQEIGGGLTIIKNGEELHSVPLPIAGLLSDQSAEQVNQSLLTLHDKLSLIGFTGG
HHHHHHHHHCCCEEEEECCCHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCC
FNPFLTLSFLALPVIPDIKMTTTGLFDVKSFQHISLQ
CCHHHHHHHHHHHCCCCCEEEECCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550522; 8969500; 9384377