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The map label for this gene is yyaE

Identifier: 16081145

GI number: 16081145

Start: 4201070

End: 4203073

Strand: Reverse

Name: yyaE

Synonym: BSU40930

Alternate gene names: 16081145

Gene position: 4203073-4201070 (Counterclockwise)

Preceding gene: 255767877

Following gene: 16081144

Centisome position: 99.7

GC content: 45.96

Gene sequence:

>2004_bases
ATGAGCAAAGTGCATCAGTCGGCATGTCCGCTGAATTGTTGGGACAGCTGCGGCTTTTTGGTGACTGTTGATGATGGAAA
GGTAACAAAAGTGGACGGAGATCCAAACCATCCGATTACGGAAGGTAAAATCTGCGGCCGCGGCAGAATGCTTGAGACAA
AAACAAATTCGCCTGATCGGCTTCGCTATCCAATGAAAAAACAAAATGGCGAGTTTGTGCGGATTTCTTGGGAGCAGGCA
CTTGATGAAATTGCCGATAAACTTCGGGAAATCAAGGAAACGTCGGAGACGACTGCTGTTTTGCACAGCCATGATTATGC
GAATAACGGTCTGTTAAAAGCGCTTGATCAGCGTTTTTTTAATGGATATGGCGGCGTGACCGAAATCGTCGGAAGCATAT
GCTGGGGCTCCGGTATCGAGGCGCAAAGCTGGGATTTTGGCCGTTCGTACGGTCACGGACCGCTTGATATTTACAACAGC
AAGCATGTTGTTGTGTGGGGAAGAAATGTATCAAGAACAAATATGCACTTATACCATCACTTGCAGCAGGTGAAAAAGAA
GGGCGCCACGATTACGGTGATTGATCCGATCTTCAACCCGACTGCTAAGCTTGCCGACCGCTATATCTCTGTAAAGCCTG
GAATGGACGGCTGGCTTGCGGCAGCCGTTTTGAAGGTTCTGATTGAGATGGGAAGAACGGATGAAACGTTTATTTCTGAG
CATTCTGTCGGTTTTGATGATGTGAAAGAGCTTTTGAAGACCGTTTCTCTGGAAGAGTTTATTGTGAAAACAGAAACTTC
TATGGAGGAGCTGGAGTATTTGGCAGGTTTGTATGCTGATGGTCCGGTGTCTACTTTTATGGGGCTTGGCATGCAGCGAT
ATAAAAACGGCGGGGGAACGATTCGTTGGATTGATGCACTTGTGGCGGCAAGCGGAAATGTCGGAATTAAGGGCGGCGGC
GCGAATTTCGGAAATGTCCAGATTGGTGAGAGCTTTGCAAAAACAAAGCTGACGCTGCCGGAATTAAAAACAACATCCCG
TTCTTTTTCAATGATGACACAGGCTGAAGAAGTGTTGACCGCTGCTGATCCTGCGATTGAGATGATTATTGTGACGTGCG
GAAATCCGCTGACTCAGGTGCCGAATACAAATAAGGTGAGACAAGCATTTGAAAAGGTTCCAATGACGGTCGCGATTGAT
TCCATTATGACGGATACCGCAGAGCTGTGTGATTATGTTTTGCCGACTGCCACTGTTTTTGAAGAAGAAGATATCTACTA
TTCCAGTATGTATCATCATTATGTTCAGTACGGGAAGAAGCTTGTGGAGCCGCAGGGTGAAGCGAAATCGGACAGCTGGA
TCTGGTCAGAGCTTGCAAAACGTCTTGGGTTTGGCGAGCTGTTTGAATACAGCACTCAAGAATTTTTAGAGATGGGGCTT
TCTTCATTGGAAGCAGAGGATGTGACACTTGAGCGTTTAAAAGAAAAAGGCCACCTCCCTCTTCCAGTAAAACAGGTGCC
GTGGGATGATTATCAGTTTTTGACGCCGAGTGGAAAATTTGAATTTACTTCGTCGCTAGCTGAGCAAAAAGGATTTAGCG
GCTCGCTTCAATTAAATGTGCCCGAAGAATCTGTTTTCCATAATGAGGAGTTAGCTGGAAAGTACCCTTATACGCTCTTA
TCCATTCATCCGCAGCGTTCCAATCATTCACAGCATGTGCCGTTTATTGAAAAGCTTCAGCACGTTCAGGTCGATATTTC
TCCAGATATAGCGGCTGGGCAGGATCTTCAGGATGGAGACGAAGTTGTCATCTTTAATGACCGCGGAAGCATGAAGGGCA
AGGTGAAAGTGATGAAGCAGGCTCATGCGAAGACGATTAATATAGATGAAGGCATGTGGGCGGCTTTTGGAGGGTCAGTC
AATGCACTGACAAATGATACAAATTCTGATAATGGAATGGGAAGTACGCTTTTTGACTGTTTAGTAGGCTTGAAAAAAGC
ATAA

Upstream 100 bases:

>100_bases
AAAGAAAACTAAAAAAAGTACTAGTCAAGCATGAGGAGCCTACTTCATAAATAGGCCGACACTCATGCTTTTTCATATAG
AAGGTAAGGAGAAGACGGCG

Downstream 100 bases:

>100_bases
TCAAAGGGATTGGCAAGCTGAAAATGCTTTTTTGTCAGCTTGTCTTTTCCAGTGAACCTCCTTATAATTGCTCTAGGTTC
AAAATACGTTCATACAATGA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 667; Mature: 666

Protein sequence:

>667_residues
MSKVHQSACPLNCWDSCGFLVTVDDGKVTKVDGDPNHPITEGKICGRGRMLETKTNSPDRLRYPMKKQNGEFVRISWEQA
LDEIADKLREIKETSETTAVLHSHDYANNGLLKALDQRFFNGYGGVTEIVGSICWGSGIEAQSWDFGRSYGHGPLDIYNS
KHVVVWGRNVSRTNMHLYHHLQQVKKKGATITVIDPIFNPTAKLADRYISVKPGMDGWLAAAVLKVLIEMGRTDETFISE
HSVGFDDVKELLKTVSLEEFIVKTETSMEELEYLAGLYADGPVSTFMGLGMQRYKNGGGTIRWIDALVAASGNVGIKGGG
ANFGNVQIGESFAKTKLTLPELKTTSRSFSMMTQAEEVLTAADPAIEMIIVTCGNPLTQVPNTNKVRQAFEKVPMTVAID
SIMTDTAELCDYVLPTATVFEEEDIYYSSMYHHYVQYGKKLVEPQGEAKSDSWIWSELAKRLGFGELFEYSTQEFLEMGL
SSLEAEDVTLERLKEKGHLPLPVKQVPWDDYQFLTPSGKFEFTSSLAEQKGFSGSLQLNVPEESVFHNEELAGKYPYTLL
SIHPQRSNHSQHVPFIEKLQHVQVDISPDIAAGQDLQDGDEVVIFNDRGSMKGKVKVMKQAHAKTINIDEGMWAAFGGSV
NALTNDTNSDNGMGSTLFDCLVGLKKA

Sequences:

>Translated_667_residues
MSKVHQSACPLNCWDSCGFLVTVDDGKVTKVDGDPNHPITEGKICGRGRMLETKTNSPDRLRYPMKKQNGEFVRISWEQA
LDEIADKLREIKETSETTAVLHSHDYANNGLLKALDQRFFNGYGGVTEIVGSICWGSGIEAQSWDFGRSYGHGPLDIYNS
KHVVVWGRNVSRTNMHLYHHLQQVKKKGATITVIDPIFNPTAKLADRYISVKPGMDGWLAAAVLKVLIEMGRTDETFISE
HSVGFDDVKELLKTVSLEEFIVKTETSMEELEYLAGLYADGPVSTFMGLGMQRYKNGGGTIRWIDALVAASGNVGIKGGG
ANFGNVQIGESFAKTKLTLPELKTTSRSFSMMTQAEEVLTAADPAIEMIIVTCGNPLTQVPNTNKVRQAFEKVPMTVAID
SIMTDTAELCDYVLPTATVFEEEDIYYSSMYHHYVQYGKKLVEPQGEAKSDSWIWSELAKRLGFGELFEYSTQEFLEMGL
SSLEAEDVTLERLKEKGHLPLPVKQVPWDDYQFLTPSGKFEFTSSLAEQKGFSGSLQLNVPEESVFHNEELAGKYPYTLL
SIHPQRSNHSQHVPFIEKLQHVQVDISPDIAAGQDLQDGDEVVIFNDRGSMKGKVKVMKQAHAKTINIDEGMWAAFGGSV
NALTNDTNSDNGMGSTLFDCLVGLKKA
>Mature_666_residues
SKVHQSACPLNCWDSCGFLVTVDDGKVTKVDGDPNHPITEGKICGRGRMLETKTNSPDRLRYPMKKQNGEFVRISWEQAL
DEIADKLREIKETSETTAVLHSHDYANNGLLKALDQRFFNGYGGVTEIVGSICWGSGIEAQSWDFGRSYGHGPLDIYNSK
HVVVWGRNVSRTNMHLYHHLQQVKKKGATITVIDPIFNPTAKLADRYISVKPGMDGWLAAAVLKVLIEMGRTDETFISEH
SVGFDDVKELLKTVSLEEFIVKTETSMEELEYLAGLYADGPVSTFMGLGMQRYKNGGGTIRWIDALVAASGNVGIKGGGA
NFGNVQIGESFAKTKLTLPELKTTSRSFSMMTQAEEVLTAADPAIEMIIVTCGNPLTQVPNTNKVRQAFEKVPMTVAIDS
IMTDTAELCDYVLPTATVFEEEDIYYSSMYHHYVQYGKKLVEPQGEAKSDSWIWSELAKRLGFGELFEYSTQEFLEMGLS
SLEAEDVTLERLKEKGHLPLPVKQVPWDDYQFLTPSGKFEFTSSLAEQKGFSGSLQLNVPEESVFHNEELAGKYPYTLLS
IHPQRSNHSQHVPFIEKLQHVQVDISPDIAAGQDLQDGDEVVIFNDRGSMKGKVKVMKQAHAKTINIDEGMWAAFGGSVN
ALTNDTNSDNGMGSTLFDCLVGLKKA

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family

Homologues:

Organism=Escherichia coli, GI171474008, Length=760, Percent_Identity=27.5, Blast_Score=212, Evalue=7e-56,
Organism=Escherichia coli, GI87081797, Length=769, Percent_Identity=28.8686605981795, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1787870, Length=767, Percent_Identity=27.9009126466754, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI3868721, Length=567, Percent_Identity=24.3386243386243, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081994, Length=771, Percent_Identity=24.254215304799, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1787231, Length=705, Percent_Identity=22.9787234042553, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI145693196, Length=723, Percent_Identity=24.3430152143845, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788534, Length=541, Percent_Identity=22.365988909427, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI3868719, Length=254, Percent_Identity=26.7716535433071, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI3868720, Length=391, Percent_Identity=24.5524296675192, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YYAE_BACSU (P37519)

Other databases:

- EMBL:   D26185
- EMBL:   AL009126
- EMBL:   X62539
- PIR:   S66017
- RefSeq:   NP_391973.1
- ProteinModelPortal:   P37519
- SMR:   P37519
- EnsemblBacteria:   EBBACT00000004020
- GeneID:   937914
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU40930
- NMPDR:   fig|224308.1.peg.4099
- GenoList:   BSU40930
- GeneTree:   EBGT00070000031948
- HOGENOM:   HBG687880
- OMA:   SACPLNC
- PhylomeDB:   P37519
- ProtClustDB:   CLSK888215
- BioCyc:   BSUB:BSU40930-MONOMER
- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- Gene3D:   G3DSA:2.40.40.20
- SMART:   SM00926

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding; SSF50692 Asp_decarb_fold

EC number: 1.8.99.- [C]

Molecular weight: Translated: 73937; Mature: 73805

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00551 MOLYBDOPTERIN_PROK_1; PS00490 MOLYBDOPTERIN_PROK_2; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVHQSACPLNCWDSCGFLVTVDDGKVTKVDGDPNHPITEGKICGRGRMLETKTNSPDR
CCCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEECCCCCEEECCCCCCHH
LRYPMKKQNGEFVRISWEQALDEIADKLREIKETSETTAVLHSHDYANNGLLKALDQRFF
EECCHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHH
NGYGGVTEIVGSICWGSGIEAQSWDFGRSYGHGPLDIYNSKHVVVWGRNVSRTNMHLYHH
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHH
LQQVKKKGATITVIDPIFNPTAKLADRYISVKPGMDGWLAAAVLKVLIEMGRTDETFISE
HHHHHHCCCEEEEECCCCCCHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHH
HSVGFDDVKELLKTVSLEEFIVKTETSMEELEYLAGLYADGPVSTFMGLGMQRYKNGGGT
CCCCHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCE
IRWIDALVAASGNVGIKGGGANFGNVQIGESFAKTKLTLPELKTTSRSFSMMTQAEEVLT
EHHHHHHHHCCCCCEEECCCCCCCCEEECCHHHHHCCCCCHHHHCCHHHHHHHHHHHHHH
AADPAIEMIIVTCGNPLTQVPNTNKVRQAFEKVPMTVAIDSIMTDTAELCDYVLPTATVF
HCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHCCCHHEE
EEEDIYYSSMYHHYVQYGKKLVEPQGEAKSDSWIWSELAKRLGFGELFEYSTQEFLEMGL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SSLEAEDVTLERLKEKGHLPLPVKQVPWDDYQFLTPSGKFEFTSSLAEQKGFSGSLQLNV
HHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEEEC
PEESVFHNEELAGKYPYTLLSIHPQRSNHSQHVPFIEKLQHVQVDISPDIAAGQDLQDGD
CHHHHHCCHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHEEEECCCCCCCCCCCCCCC
EVVIFNDRGSMKGKVKVMKQAHAKTINIDEGMWAAFGGSVNALTNDTNSDNGMGSTLFDC
EEEEECCCCCCCHHHHHHHHHCCCEEECCCCCEECCCCCEEEEECCCCCCCCCHHHHHHH
LVGLKKA
HHHHCCC
>Mature Secondary Structure 
SKVHQSACPLNCWDSCGFLVTVDDGKVTKVDGDPNHPITEGKICGRGRMLETKTNSPDR
CCCCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEECCCCCEEECCCCCCHH
LRYPMKKQNGEFVRISWEQALDEIADKLREIKETSETTAVLHSHDYANNGLLKALDQRFF
EECCHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHH
NGYGGVTEIVGSICWGSGIEAQSWDFGRSYGHGPLDIYNSKHVVVWGRNVSRTNMHLYHH
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCHHHHHHHH
LQQVKKKGATITVIDPIFNPTAKLADRYISVKPGMDGWLAAAVLKVLIEMGRTDETFISE
HHHHHHCCCEEEEECCCCCCHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHH
HSVGFDDVKELLKTVSLEEFIVKTETSMEELEYLAGLYADGPVSTFMGLGMQRYKNGGGT
CCCCHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCHHHHHCCCCE
IRWIDALVAASGNVGIKGGGANFGNVQIGESFAKTKLTLPELKTTSRSFSMMTQAEEVLT
EHHHHHHHHCCCCCEEECCCCCCCCEEECCHHHHHCCCCCHHHHCCHHHHHHHHHHHHHH
AADPAIEMIIVTCGNPLTQVPNTNKVRQAFEKVPMTVAIDSIMTDTAELCDYVLPTATVF
HCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHCCCHHEE
EEEDIYYSSMYHHYVQYGKKLVEPQGEAKSDSWIWSELAKRLGFGELFEYSTQEFLEMGL
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
SSLEAEDVTLERLKEKGHLPLPVKQVPWDDYQFLTPSGKFEFTSSLAEQKGFSGSLQLNV
HHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCEEEEEC
PEESVFHNEELAGKYPYTLLSIHPQRSNHSQHVPFIEKLQHVQVDISPDIAAGQDLQDGD
CHHHHHCCHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHEEEECCCCCCCCCCCCCCC
EVVIFNDRGSMKGKVKVMKQAHAKTINIDEGMWAAFGGSVNALTNDTNSDNGMGSTLFDC
EEEEECCCCCCCHHHHHHHHHCCCEEECCCCCEECCCCCEEEEECCCCCCCCCHHHHHHH
LVGLKKA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: Fe; Mo [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1552862