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The map label for this gene is ywbH

Identifier: 16080883

GI number: 16080883

Start: 3933209

End: 3933595

Strand: Direct

Name: ywbH

Synonym: BSU38320

Alternate gene names: 16080883

Gene position: 3933209-3933595 (Clockwise)

Preceding gene: 255767812

Following gene: 255767814

Centisome position: 93.3

GC content: 40.83

Gene sequence:

>387_bases
ATGAAAAAACTGTTGCTAACCGTTATTCAAATCGCTCTGTTATTTATATTTGCTCGGCTGATTAATTGGGTGACAGCCCT
TCTTCATATAAATATTCCCGGCAGTATAATAGGGATTGTGATTCTTTTCACATTATTGCACTTTAACATTATCAAGCTTG
AATGGATCGAGCTTGGTGCAGCGTGGCTTCTCGGGGAGCTGCTTTTATTTTTTATCCCGTCTGCCGTCGGAGTGATTGAA
TACGGAGACATTATGTCGAAATTTGGTGTCAGCATTCTGCTTGTTGTCATCATCAGCACGTTTGTCGTGATGGTGTCTAC
AGGAACGCTTACACAACTCATCGCAAAGAGAAAGGAGAAAAAGCATACGTGTTCATCGGAATTGTAA

Upstream 100 bases:

>100_bases
TCACCCTTTCTATAGACAAAAGGAATACTTCTTATTCTTAATATATATTTTACCTATAGAGAGACCTTATGTACAATAAG
TATATAAGGGAGGCATCAAT

Downstream 100 bases:

>100_bases
GTTTGTTTTTAACGGTTTTGGTGTATTTAGGAGCAAAAAAGGTATATCAACGCTTTCCGCGTGTTTATACGTCGCCGCTA
TTGGTGACGCCCGCTGTATT

Product: holin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MKKLLLTVIQIALLFIFARLINWVTALLHINIPGSIIGIVILFTLLHFNIIKLEWIELGAAWLLGELLLFFIPSAVGVIE
YGDIMSKFGVSILLVVIISTFVVMVSTGTLTQLIAKRKEKKHTCSSEL

Sequences:

>Translated_128_residues
MKKLLLTVIQIALLFIFARLINWVTALLHINIPGSIIGIVILFTLLHFNIIKLEWIELGAAWLLGELLLFFIPSAVGVIE
YGDIMSKFGVSILLVVIISTFVVMVSTGTLTQLIAKRKEKKHTCSSEL
>Mature_128_residues
MKKLLLTVIQIALLFIFARLINWVTALLHINIPGSIIGIVILFTLLHFNIIKLEWIELGAAWLLGELLLFFIPSAVGVIE
YGDIMSKFGVSILLVVIISTFVVMVSTGTLTQLIAKRKEKKHTCSSEL

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788463, Length=120, Percent_Identity=35, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 14262; Mature: 14262

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLLTVIQIALLFIFARLINWVTALLHINIPGSIIGIVILFTLLHFNIIKLEWIELGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWLLGELLLFFIPSAVGVIEYGDIMSKFGVSILLVVIISTFVVMVSTGTLTQLIAKRKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KHTCSSEL
HCCCCCCC
>Mature Secondary Structure
MKKLLLTVIQIALLFIFARLINWVTALLHINIPGSIIGIVILFTLLHFNIIKLEWIELGA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWLLGELLLFFIPSAVGVIEYGDIMSKFGVSILLVVIISTFVVMVSTGTLTQLIAKRKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KHTCSSEL
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA