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The map label for this gene is lrgB

Identifier: 255767814

GI number: 255767814

Start: 3933577

End: 3934254

Strand: Direct

Name: lrgB

Synonym: BSU38330

Alternate gene names: 255767814

Gene position: 3933577-3934254 (Clockwise)

Preceding gene: 16080883

Following gene: 16080885

Centisome position: 93.31

GC content: 50.0

Gene sequence:

>678_bases
GTGTTCATCGGAATTGTAAGTTTGTTTTTAACGGTTTTGGTGTATTTAGGAGCAAAAAAGGTATATCAACGCTTTCCGCG
TGTTTATACGTCGCCGCTATTGGTGACGCCCGCTGTATTAGTCGGTCTGCTGCTGCTGGTGAATGTCCCGTACGAGTCCT
ATAATCTCGGCGGCGGATTGCTGACCGATATGCTACAGCCGGCCACCGTGGCATTCGCGATCCCGTTATATAAATATTTC
CCTGTTTTAAAGAAATACGCAGTGGAAATTATTTTGAATGTGGCCGTCGGTTCATGCATCGCGATTATTTCTACCGCTCT
TATTGCGAAATGGCTTCACCTCGGCACCGGCTTAATTGACAGCCTCGTCCCAAGATCAGTGACAACGCCGATCGCGATGA
ACGTATCTGAAATGATCGGCGGTATGCCTGCCGTCACAGCCGTGTTTGTGATTTTAACCGCTTTGCTCGGCACAGTGATC
GGCCCGATGGTCATCCGTTATTTCCGCATTGATAACGAAATTGCGCGGGGCGTGCTGCTTGGCACAAGCGCGCACGGAGC
GGGAACGTCAAAGGCATTTGAGCTCAGCTCTGTGTCCGGCACGATTTCCAGCGTGTCGATGATCTTAGCTGCGATTATGA
CGCTTTGCGCGGCGCCGTTTTTGCTTTCATTTATGTAA

Upstream 100 bases:

>100_bases
TCAGCATTCTGCTTGTTGTCATCATCAGCACGTTTGTCGTGATGGTGTCTACAGGAACGCTTACACAACTCATCGCAAAG
AGAAAGGAGAAAAAGCATAC

Downstream 100 bases:

>100_bases
AAAACTGTCCTCTCGAGGGCAGTTTTTTTTATGTGCTTCCCCTTATTGAAAAGCTGGCGAATTCCAATATAATGTATTTG
TGGATACCAAAGGAGGCACC

Product: anti-holin factor controlling activity of murein hydrolases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MFIGIVSLFLTVLVYLGAKKVYQRFPRVYTSPLLVTPAVLVGLLLLVNVPYESYNLGGGLLTDMLQPATVAFAIPLYKYF
PVLKKYAVEIILNVAVGSCIAIISTALIAKWLHLGTGLIDSLVPRSVTTPIAMNVSEMIGGMPAVTAVFVILTALLGTVI
GPMVIRYFRIDNEIARGVLLGTSAHGAGTSKAFELSSVSGTISSVSMILAAIMTLCAAPFLLSFM

Sequences:

>Translated_225_residues
MFIGIVSLFLTVLVYLGAKKVYQRFPRVYTSPLLVTPAVLVGLLLLVNVPYESYNLGGGLLTDMLQPATVAFAIPLYKYF
PVLKKYAVEIILNVAVGSCIAIISTALIAKWLHLGTGLIDSLVPRSVTTPIAMNVSEMIGGMPAVTAVFVILTALLGTVI
GPMVIRYFRIDNEIARGVLLGTSAHGAGTSKAFELSSVSGTISSVSMILAAIMTLCAAPFLLSFM
>Mature_225_residues
MFIGIVSLFLTVLVYLGAKKVYQRFPRVYTSPLLVTPAVLVGLLLLVNVPYESYNLGGGLLTDMLQPATVAFAIPLYKYF
PVLKKYAVEIILNVAVGSCIAIISTALIAKWLHLGTGLIDSLVPRSVTTPIAMNVSEMIGGMPAVTAVFVILTALLGTVI
GPMVIRYFRIDNEIARGVLLGTSAHGAGTSKAFELSSVSGTISSVSMILAAIMTLCAAPFLLSFM

Specific function: Unknown

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yohK (E.coli)/ywbG (IPA-22R) (B.subtilis) family

Homologues:

Organism=Escherichia coli, GI1788464, Length=216, Percent_Identity=38.4259259259259, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YWBG_BACSU (P39590)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39677
- RefSeq:   NP_391712.2
- EnsemblBacteria:   EBBACT00000002848
- GeneID:   937323
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU38330
- NMPDR:   fig|224308.1.peg.3838
- GenoList:   BSU38330
- GeneTree:   EBGT00050000000862
- HOGENOM:   HBG363009
- PhylomeDB:   P39590
- ProtClustDB:   CLSK888105
- BioCyc:   BSUB:BSU38330-MONOMER
- InterPro:   IPR005261
- InterPro:   IPR007300
- TIGRFAMs:   TIGR00659

Pfam domain/function: PF04172 LrgB

EC number: NA

Molecular weight: Translated: 23887; Mature: 23887

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12f0e658)-; HASH(0x130236f8)-; HASH(0x122a86f8)-; HASH(0x13348b44)-; HASH(0x12590f74)-; HASH(0x12baacd4)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIGIVSLFLTVLVYLGAKKVYQRFPRVYTSPLLVTPAVLVGLLLLVNVPYESYNLGGGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHCCCCHHH
LTDMLQPATVAFAIPLYKYFPVLKKYAVEIILNVAVGSCIAIISTALIAKWLHLGTGLID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVPRSVTTPIAMNVSEMIGGMPAVTAVFVILTALLGTVIGPMVIRYFRIDNEIARGVLL
HHCCCCCCCHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTSAHGAGTSKAFELSSVSGTISSVSMILAAIMTLCAAPFLLSFM
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFIGIVSLFLTVLVYLGAKKVYQRFPRVYTSPLLVTPAVLVGLLLLVNVPYESYNLGGGL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHCCCCHHH
LTDMLQPATVAFAIPLYKYFPVLKKYAVEIILNVAVGSCIAIISTALIAKWLHLGTGLID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVPRSVTTPIAMNVSEMIGGMPAVTAVFVILTALLGTVIGPMVIRYFRIDNEIARGVLL
HHCCCCCCCHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GTSAHGAGTSKAFELSSVSGTISSVSMILAAIMTLCAAPFLLSFM
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377