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The map label for this gene is rocC

Identifier: 16080828

GI number: 16080828

Start: 3875780

End: 3877192

Strand: Reverse

Name: rocC

Synonym: BSU37760

Alternate gene names: 16080828

Gene position: 3877192-3875780 (Counterclockwise)

Preceding gene: 16080829

Following gene: 16080827

Centisome position: 91.97

GC content: 47.13

Gene sequence:

>1413_bases
ATGCAGAATCATAAAAATGAATTGCAGCGCAGCATGAAAAGCAGGCATTTGTTTATGATTGCTTTGGGAGGGGTGATTGG
CACTGGGCTGTTTCTAGGCTCTGGCTTTACCATTAGCCAGGCGGGACCGCTCGGCGCCATTGCCGCGTATATCATCGGCG
GATTTTTAATGTATCTCGTCATGCTTTGTTTAGGAGAATTGGCTGTTGCCATGCCGGTGGCCGGATCGTTTCAGGCCTAC
GCCACTAAATTTCTGGGACAGTCGACAGGCTTTATGATTGGCTGGCTGTATTGGTTCAGCTGGGCCAATACAGTAGGGTT
AGAGCTGACGTCAGCAGGCATTTTGATGCAAAGGTGGCTGCCCTCCGTTCCGATCTGGATATGGTGCCTCGTGTTCGGCA
TCGTCATCTTTTTGATTAATGCGCTCTCTGTCAGAAGCTTTGCGGAAATGGAATTTTGGTTTTCAAGCATCAAAGTGGCG
GCGATCATATTATTTATTGTGATTGGCGGAGCCGCTGTGTTTGGCTTGATTGACTTTAAAGGCGGACAGGAGACACCCTT
TTTGTCTAACTTTATGACTGATAGAGGGCTTTTCCCTAATGGGGTGCTGGCCGTTATGTTTACGCTGGTCATGGTAAACT
TCTCGTTCCAGGGAACGGAGCTTGTCGGCATTGCGGCAGGGGAAAGTGAAAGCCCGGAAAAAACACTGCCAAAGTCCATT
CGAAATGTTATTTGGCGCACGCTGTTTTTCTTTGTGCTCGCTATGTTCGTCTTGGTTGCCATCCTTCCGTACAAAACGGC
GGGGGTGATTGAAAGCCCGTTTGTAGCAGTACTCGATCAAATCGGCATCCCATTTTCGGCAGATATCATGAACTTTGTCA
TCTTAACGGCCATTTTATCTGTTGCTAATTCGGGATTGTATGCGGCGTCGCGTATGATGTGGTCACTTTCATCAAATCAA
ATGGGTCCCTCCTTTCTCACCAGACTGACAAAAAAAGGCGTGCCGATGAATGCCCTGCTGATTACGCTAGGCATTTCAGG
CTGTTCGCTGCTGACAAGTGTCATGGCTGCAGAAACAGTGTATTTATGGTGTATCTCAATCTCGGGCATGGTGACAGTTG
TCGCGTGGATGTCCATTTGTGCGTCGCAATTTTTCTTTCGCAGGCGTTTCCTGGCAGAAGGCGGAAATGTGAATGATCTG
GAGTTCAGAACGCCGCTTTATCCGCTAGTCCCGATTCTCGGATTTTGTTTATATGGCTGCGTGTTGATCAGCCTTATTTT
CATTCCGGATCAAAGAATTGGCTTATACTGCGGTGTGCCGATCATTATTTTCTGTTATGCATACTATCATCTAAGCATCA
AAAAGCGTATAAATCATGAAACGATTGAAAAAAAGCAGACAGAGGCGCAATAG

Upstream 100 bases:

>100_bases
CATTTCATGTATTGCCTCTCCTCATACAGCAAACCACCGTTCATCTTTTGCAAAGCTACCGGATGACCATCACGGCAAAA
GAACCAAAGGGGGAAGGATG

Downstream 100 bases:

>100_bases
AAAAAGCTCTCCGGGAGGCCGGAGAGCTTTTTTTACGTGTTACATCCTCATGTATTTTTAGAATGAAATATAGAAATATA
TAATGGGATTTAAATGAAAA

Product: arginine/ornithine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MQNHKNELQRSMKSRHLFMIALGGVIGTGLFLGSGFTISQAGPLGAIAAYIIGGFLMYLVMLCLGELAVAMPVAGSFQAY
ATKFLGQSTGFMIGWLYWFSWANTVGLELTSAGILMQRWLPSVPIWIWCLVFGIVIFLINALSVRSFAEMEFWFSSIKVA
AIILFIVIGGAAVFGLIDFKGGQETPFLSNFMTDRGLFPNGVLAVMFTLVMVNFSFQGTELVGIAAGESESPEKTLPKSI
RNVIWRTLFFFVLAMFVLVAILPYKTAGVIESPFVAVLDQIGIPFSADIMNFVILTAILSVANSGLYAASRMMWSLSSNQ
MGPSFLTRLTKKGVPMNALLITLGISGCSLLTSVMAAETVYLWCISISGMVTVVAWMSICASQFFFRRRFLAEGGNVNDL
EFRTPLYPLVPILGFCLYGCVLISLIFIPDQRIGLYCGVPIIIFCYAYYHLSIKKRINHETIEKKQTEAQ

Sequences:

>Translated_470_residues
MQNHKNELQRSMKSRHLFMIALGGVIGTGLFLGSGFTISQAGPLGAIAAYIIGGFLMYLVMLCLGELAVAMPVAGSFQAY
ATKFLGQSTGFMIGWLYWFSWANTVGLELTSAGILMQRWLPSVPIWIWCLVFGIVIFLINALSVRSFAEMEFWFSSIKVA
AIILFIVIGGAAVFGLIDFKGGQETPFLSNFMTDRGLFPNGVLAVMFTLVMVNFSFQGTELVGIAAGESESPEKTLPKSI
RNVIWRTLFFFVLAMFVLVAILPYKTAGVIESPFVAVLDQIGIPFSADIMNFVILTAILSVANSGLYAASRMMWSLSSNQ
MGPSFLTRLTKKGVPMNALLITLGISGCSLLTSVMAAETVYLWCISISGMVTVVAWMSICASQFFFRRRFLAEGGNVNDL
EFRTPLYPLVPILGFCLYGCVLISLIFIPDQRIGLYCGVPIIIFCYAYYHLSIKKRINHETIEKKQTEAQ
>Mature_470_residues
MQNHKNELQRSMKSRHLFMIALGGVIGTGLFLGSGFTISQAGPLGAIAAYIIGGFLMYLVMLCLGELAVAMPVAGSFQAY
ATKFLGQSTGFMIGWLYWFSWANTVGLELTSAGILMQRWLPSVPIWIWCLVFGIVIFLINALSVRSFAEMEFWFSSIKVA
AIILFIVIGGAAVFGLIDFKGGQETPFLSNFMTDRGLFPNGVLAVMFTLVMVNFSFQGTELVGIAAGESESPEKTLPKSI
RNVIWRTLFFFVLAMFVLVAILPYKTAGVIESPFVAVLDQIGIPFSADIMNFVILTAILSVANSGLYAASRMMWSLSSNQ
MGPSFLTRLTKKGVPMNALLITLGISGCSLLTSVMAAETVYLWCISISGMVTVVAWMSICASQFFFRRRFLAEGGNVNDL
EFRTPLYPLVPILGFCLYGCVLISLIFIPDQRIGLYCGVPIIIFCYAYYHLSIKKRINHETIEKKQTEAQ

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily

Homologues:

Organism=Escherichia coli, GI87081708, Length=460, Percent_Identity=50.6521739130435, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1788480, Length=482, Percent_Identity=41.2863070539419, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1786302, Length=435, Percent_Identity=37.9310344827586, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI48994972, Length=454, Percent_Identity=37.4449339207048, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1786789, Length=434, Percent_Identity=37.5576036866359, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1789017, Length=454, Percent_Identity=35.2422907488987, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1786602, Length=463, Percent_Identity=36.9330453563715, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI87081915, Length=411, Percent_Identity=34.7931873479319, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1790653, Length=390, Percent_Identity=34.3589743589744, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI87081869, Length=239, Percent_Identity=23.8493723849372, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=438, Percent_Identity=36.0730593607306, Blast_Score=275, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6324061, Length=421, Percent_Identity=33.4916864608076, Blast_Score=245, Evalue=9e-66,
Organism=Saccharomyces cerevisiae, GI6324553, Length=404, Percent_Identity=34.1584158415842, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6324059, Length=441, Percent_Identity=33.1065759637188, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6322892, Length=416, Percent_Identity=32.2115384615385, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6324990, Length=492, Percent_Identity=28.2520325203252, Blast_Score=209, Evalue=8e-55,
Organism=Saccharomyces cerevisiae, GI6319824, Length=446, Percent_Identity=30.4932735426009, Blast_Score=206, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6321629, Length=482, Percent_Identity=28.8381742738589, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320251, Length=419, Percent_Identity=29.1169451073986, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6320717, Length=424, Percent_Identity=28.7735849056604, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6319542, Length=416, Percent_Identity=30.5288461538462, Blast_Score=192, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6324924, Length=455, Percent_Identity=29.2307692307692, Blast_Score=190, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6319543, Length=412, Percent_Identity=28.3980582524272, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6321053, Length=490, Percent_Identity=24.4897959183673, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6322967, Length=483, Percent_Identity=27.7432712215321, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324981, Length=487, Percent_Identity=28.952772073922, Blast_Score=169, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6319608, Length=440, Percent_Identity=27.7272727272727, Blast_Score=166, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6320364, Length=496, Percent_Identity=22.1774193548387, Blast_Score=103, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ROCC_BACSU (P39636)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39733
- RefSeq:   NP_391656.1
- ProteinModelPortal:   P39636
- EnsemblBacteria:   EBBACT00000001643
- GeneID:   938495
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU37760
- NMPDR:   fig|224308.1.peg.3782
- GenoList:   BSU37760
- GeneTree:   EBGT00070000031926
- HOGENOM:   HBG492579
- OMA:   QRIGLYC
- PhylomeDB:   P39636
- ProtClustDB:   CLSK888076
- BioCyc:   BSUB:BSU37760-MONOMER
- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840
- PANTHER:   PTHR11785
- PIRSF:   PIRSF006060

Pfam domain/function: PF00324 AA_permease

EC number: NA

Molecular weight: Translated: 51731; Mature: 51731

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1314d110)-; HASH(0x124abcd4)-; HASH(0x12ee524c)-; HASH(0x13025fcc)-; HASH(0x12b21c48)-; HASH(0x11ff401c)-; HASH(0x100f6de0)-; HASH(0x10a4c9b8)-; HASH(0x1262c548)-; HASH(0x11c629e8)-; HASH(0x12fd4fb0)-; HASH(0x12bdc250)-;

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCH
>Mature Secondary Structure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HHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377