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The map label for this gene is bacE

Identifier: 16080822

GI number: 16080822

Start: 3869487

End: 3870671

Strand: Reverse

Name: bacE

Synonym: BSU37700

Alternate gene names: 16080822

Gene position: 3870671-3869487 (Counterclockwise)

Preceding gene: 16080823

Following gene: 16080821

Centisome position: 91.82

GC content: 45.99

Gene sequence:

>1185_bases
ATGAAACAGCTGAAACCCAACTCTAAATACTTGCTTTACGGGCAGGCGCTATCGTTCATGGGAGACTATTGTGTTCTCCC
TGCCCTGCTCATTTTGTCTACATATTATCACGATTATTGGGTGACGTCCGGGGTCATCGTGGTCAGAAGCATTCCGATGG
TGTTTCAGCCGTTTTTGGGTGTTCTGGTCGACCGGTTAGACAGAATTAAGATCATGCTGTGGACGGATATCATCAGAGGC
ATCATCTTTTTGGGGCTCACATTTCTTCCAAAAGGCGAGTATCCGCTGATTTTTCTGGCCCTGCTGTTTATTACTTATGG
AAGCGGCGTGTTTTTTAATCCCGCCCGTCTCGCTGTCATGTCGTCCTTGGAATCAGATATTAAAAGCATCAACACGTTAT
TTGCAAAAGCGACAACCATCTCCATTATCGTCGGGGCGGCTGCCGGAGGGCTCTTTCTGTTAGGCGGATCTGTAGAGCTG
GCTGTTGCCTTTAACGGTGTGACATACTTGGTTTCGGCATTTTTTATCAGCCGCATCAAGCTGCAATTTGTGCCGATTCA
ATCTGAAAACATTAAAGAGGCCTTTCAGTCTTTTAAGGAAGGACTCAAGGAAATCAAAACCAATTCATTCGTATTAAACG
CCATGTTTACGATGATTACAATGGCTTTGCTGTGGGGAGTTGTGTACAGCTATTTTCCGATTGTCAGCCGCTTTCTGGGT
GACGGGGAAATCGGCAACTTTATTCTCACGTTCTGCATCGGCTTCGGCGGCTTTATCGGAGCGGCGCTTGTCAGCAAATG
GGGCTTTAACAACAATAGAGGCCTGACGTACTTTACCGTTTTATCCATTGTCTCGCTGGCGCTGTTTTTATTCACACCGA
TATTCGCTGTTTCTGTCATCGCGGCGATCCTCTTTTTCATCGCGATGGAATACGGGGAAGTGCTTGCAAAAGTGAAGGTT
CAGGAAAATGCGGCAAACCAGATTCAAGGGCGCATTTTTTCAGTGGCCGAAGCGTCTATCGGATTATGCATTTCTATTGG
TTCAATGTTCATTAACATCCTAAGCGCTCCGGTCATTATGGGGCTGATTGTCGTGATCGTATGCGGTTTGTTTTTGCATA
CGAAGCTCGTCAACAAATCGTTTTTGGAACGGGATAACAAAACGGAGCAAAAAGGAGTCTTTTAG

Upstream 100 bases:

>100_bases
CTGCATTTGAACTGAAAGGCAGTAATTCACAGGATGTGGCTGAATCAATCAGACAAATTCAGCAGCATGCGAAGCTGACG
GCAAAGTATGTGCTGCCAGT

Downstream 100 bases:

>100_bases
ATGGAAATAACACCGTCCGATGTCATCAAGACACTTCCAAGGCAGGAGTTTTCTCTCGTTTTTCAAAAGGTAAAGGAAAT
GGAAAAAACGGGAGCCCATA

Product: efflux protein for bacilysin excretion, self-protection against bacilysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MKQLKPNSKYLLYGQALSFMGDYCVLPALLILSTYYHDYWVTSGVIVVRSIPMVFQPFLGVLVDRLDRIKIMLWTDIIRG
IIFLGLTFLPKGEYPLIFLALLFITYGSGVFFNPARLAVMSSLESDIKSINTLFAKATTISIIVGAAAGGLFLLGGSVEL
AVAFNGVTYLVSAFFISRIKLQFVPIQSENIKEAFQSFKEGLKEIKTNSFVLNAMFTMITMALLWGVVYSYFPIVSRFLG
DGEIGNFILTFCIGFGGFIGAALVSKWGFNNNRGLTYFTVLSIVSLALFLFTPIFAVSVIAAILFFIAMEYGEVLAKVKV
QENAANQIQGRIFSVAEASIGLCISIGSMFINILSAPVIMGLIVVIVCGLFLHTKLVNKSFLERDNKTEQKGVF

Sequences:

>Translated_394_residues
MKQLKPNSKYLLYGQALSFMGDYCVLPALLILSTYYHDYWVTSGVIVVRSIPMVFQPFLGVLVDRLDRIKIMLWTDIIRG
IIFLGLTFLPKGEYPLIFLALLFITYGSGVFFNPARLAVMSSLESDIKSINTLFAKATTISIIVGAAAGGLFLLGGSVEL
AVAFNGVTYLVSAFFISRIKLQFVPIQSENIKEAFQSFKEGLKEIKTNSFVLNAMFTMITMALLWGVVYSYFPIVSRFLG
DGEIGNFILTFCIGFGGFIGAALVSKWGFNNNRGLTYFTVLSIVSLALFLFTPIFAVSVIAAILFFIAMEYGEVLAKVKV
QENAANQIQGRIFSVAEASIGLCISIGSMFINILSAPVIMGLIVVIVCGLFLHTKLVNKSFLERDNKTEQKGVF
>Mature_394_residues
MKQLKPNSKYLLYGQALSFMGDYCVLPALLILSTYYHDYWVTSGVIVVRSIPMVFQPFLGVLVDRLDRIKIMLWTDIIRG
IIFLGLTFLPKGEYPLIFLALLFITYGSGVFFNPARLAVMSSLESDIKSINTLFAKATTISIIVGAAAGGLFLLGGSVEL
AVAFNGVTYLVSAFFISRIKLQFVPIQSENIKEAFQSFKEGLKEIKTNSFVLNAMFTMITMALLWGVVYSYFPIVSRFLG
DGEIGNFILTFCIGFGGFIGAALVSKWGFNNNRGLTYFTVLSIVSLALFLFTPIFAVSVIAAILFFIAMEYGEVLAKVKV
QENAANQIQGRIFSVAEASIGLCISIGSMFINILSAPVIMGLIVVIVCGLFLHTKLVNKSFLERDNKTEQKGVF

Specific function: Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BACE_BACSU (P39642)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39739
- RefSeq:   NP_391650.1
- ProteinModelPortal:   P39642
- EnsemblBacteria:   EBBACT00000002624
- GeneID:   937161
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU37700
- NMPDR:   fig|224308.1.peg.3776
- GenoList:   BSU37700
- GeneTree:   EBGT00070000032489
- HOGENOM:   HBG338437
- OMA:   QENAANQ
- ProtClustDB:   CLSK888070
- BioCyc:   BSUB:BSU37700-MONOMER
- InterPro:   IPR022324
- InterPro:   IPR011701
- InterPro:   IPR016196
- PRINTS:   PR01988

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 43417; Mature: 43417

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12f4a438)-; HASH(0x131c0c34)-; HASH(0x130f0998)-; HASH(0xf268130)-; HASH(0x12dfae00)-; HASH(0x131ced08)-; HASH(0x1307a9e8)-; HASH(0x12eecaac)-; HASH(0x11f7a5d4)-; HASH(0x131c6320)-; HASH(0xc57231c)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLKPNSKYLLYGQALSFMGDYCVLPALLILSTYYHDYWVTSGVIVVRSIPMVFQPFLG
CCCCCCCCCEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLVDRLDRIKIMLWTDIIRGIIFLGLTFLPKGEYPLIFLALLFITYGSGVFFNPARLAVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECHHHHHHH
SSLESDIKSINTLFAKATTISIIVGAAAGGLFLLGGSVELAVAFNGVTYLVSAFFISRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHH
LQFVPIQSENIKEAFQSFKEGLKEIKTNSFVLNAMFTMITMALLWGVVYSYFPIVSRFLG
EEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGEIGNFILTFCIGFGGFIGAALVSKWGFNNNRGLTYFTVLSIVSLALFLFTPIFAVSVI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAILFFIAMEYGEVLAKVKVQENAANQIQGRIFSVAEASIGLCISIGSMFINILSAPVIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLIVVIVCGLFLHTKLVNKSFLERDNKTEQKGVF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
>Mature Secondary Structure
MKQLKPNSKYLLYGQALSFMGDYCVLPALLILSTYYHDYWVTSGVIVVRSIPMVFQPFLG
CCCCCCCCCEEEEHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLVDRLDRIKIMLWTDIIRGIIFLGLTFLPKGEYPLIFLALLFITYGSGVFFNPARLAVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEECHHHHHHH
SSLESDIKSINTLFAKATTISIIVGAAAGGLFLLGGSVELAVAFNGVTYLVSAFFISRIK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEEEECCHHHHHHHHHHHHHH
LQFVPIQSENIKEAFQSFKEGLKEIKTNSFVLNAMFTMITMALLWGVVYSYFPIVSRFLG
EEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGEIGNFILTFCIGFGGFIGAALVSKWGFNNNRGLTYFTVLSIVSLALFLFTPIFAVSVI
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AAILFFIAMEYGEVLAKVKVQENAANQIQGRIFSVAEASIGLCISIGSMFINILSAPVIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLIVVIVCGLFLHTKLVNKSFLERDNKTEQKGVF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377