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The map label for this gene is ywfG

Identifier: 16080821

GI number: 16080821

Start: 3868287

End: 3869486

Strand: Reverse

Name: ywfG

Synonym: BSU37690

Alternate gene names: 16080821

Gene position: 3869486-3868287 (Counterclockwise)

Preceding gene: 16080822

Following gene: 16080818

Centisome position: 91.79

GC content: 47.0

Gene sequence:

>1200_bases
ATGGAAATAACACCGTCCGATGTCATCAAGACACTTCCAAGGCAGGAGTTTTCTCTCGTTTTTCAAAAGGTAAAGGAAAT
GGAAAAAACGGGAGCCCATATCATTAATCTCGGACAGGGGAACCCTGACCTTCCCACTCCGCCGCATATTGTCGAGGCTT
TGCGGGAGGCTTCTCTGAATCCTTCGTTTCATGGATACGGCCCTTTCAGGGGCTATCCTTTTTTAAAGGAAGCGATCGCC
GCTTTCTATAAAAGGGAATACGGAGTGACAATCAATCCTGAAACGGAAGTCGCGCTTTTCGGAGGCGGGAAAGCCGGATT
GTATGTGCTGACACAATGCCTGCTCAATCCGGGAGACATCGCTTTAGTCCCGAATCCAGGCTATCCTGAATATTTATCAG
GGATTACGATGGCGCGAGCTGAGCTTTACGAAATGCCGCTGTATGAAGAAAATGGCTATCTGCCGGATTTTGAAAAGATT
GATCCAGCCGTGCTGGAAAAAGCGAAGCTTATGTTTTTAAACTATCCGAACAACCCCACTGGAGCTGTGGCTGATGCGGC
TTTTTATGCAAAAGCTGCTGCTTTTGCGAAAGAGCATAACATCCATTTGATTCATGATTTTGCATACGGGGCGTTTGAAT
TCGATCAAAAACCGGCCAGCTTTCTTGAGGCAGAGGATGCCAAAACTGTCGGAGCAGAGCTTTATTCATTTTCAAAAACA
TTTAACATGGCCGGCTGGAGAATGGCGTTTGCGGTTGGGAACGAAAAAATCATTCAGGCCGTCAATGAATTTCAGGATCA
TGTATTTGTCGGCATGTTCGGCGGGCTGCAGCAGGCAGCGAGTGCGGCGCTTTCTGGAGATCCGGAGCATACGGAATCGT
TGAAACGAATTTATAAGGAACGAATTGACTTTTTTACGGCGCTTTGTGAAAAGGAACTGGGCTGGAAGATGGAAAAGCCA
AAAGGAACCTTTTACGTATGGGCTGAAATTCCGAATACGTTTGAGACATCTCACCAATTTTCCGATTACTTGCTGGAGCA
TGCCCATGTCGTAGTCACACCGGGCGAAATTTTTGGAAGCAACGGAAAAAGGCATGTCAGAATCTCAATGGTGTCGAAGC
AGGAGGATCTGCGGGAATTTGTCACGCGGATTCAAAAGCTGAACCTGCCGTTCGGGTCATTACAAGAAACATCCCGCTAA

Upstream 100 bases:

>100_bases
GATTGTCGTGATCGTATGCGGTTTGTTTTTGCATACGAAGCTCGTCAACAAATCGTTTTTGGAACGGGATAACAAAACGG
AGCAAAAAGGAGTCTTTTAG

Downstream 100 bases:

>100_bases
AAAGCGGGATGTTTTTATATGCTTTTCATGCTGCCGCCGTCAGCGGAAATTTGCTGTCCCGTGATGTAGGAGGCTTCCTC
AGAGGCAAGAAATGCGGCGA

Product: transaminase

Products: NA

Alternate protein names: AspAT; Transaminase A

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MEITPSDVIKTLPRQEFSLVFQKVKEMEKTGAHIINLGQGNPDLPTPPHIVEALREASLNPSFHGYGPFRGYPFLKEAIA
AFYKREYGVTINPETEVALFGGGKAGLYVLTQCLLNPGDIALVPNPGYPEYLSGITMARAELYEMPLYEENGYLPDFEKI
DPAVLEKAKLMFLNYPNNPTGAVADAAFYAKAAAFAKEHNIHLIHDFAYGAFEFDQKPASFLEAEDAKTVGAELYSFSKT
FNMAGWRMAFAVGNEKIIQAVNEFQDHVFVGMFGGLQQAASAALSGDPEHTESLKRIYKERIDFFTALCEKELGWKMEKP
KGTFYVWAEIPNTFETSHQFSDYLLEHAHVVVTPGEIFGSNGKRHVRISMVSKQEDLREFVTRIQKLNLPFGSLQETSR

Sequences:

>Translated_399_residues
MEITPSDVIKTLPRQEFSLVFQKVKEMEKTGAHIINLGQGNPDLPTPPHIVEALREASLNPSFHGYGPFRGYPFLKEAIA
AFYKREYGVTINPETEVALFGGGKAGLYVLTQCLLNPGDIALVPNPGYPEYLSGITMARAELYEMPLYEENGYLPDFEKI
DPAVLEKAKLMFLNYPNNPTGAVADAAFYAKAAAFAKEHNIHLIHDFAYGAFEFDQKPASFLEAEDAKTVGAELYSFSKT
FNMAGWRMAFAVGNEKIIQAVNEFQDHVFVGMFGGLQQAASAALSGDPEHTESLKRIYKERIDFFTALCEKELGWKMEKP
KGTFYVWAEIPNTFETSHQFSDYLLEHAHVVVTPGEIFGSNGKRHVRISMVSKQEDLREFVTRIQKLNLPFGSLQETSR
>Mature_399_residues
MEITPSDVIKTLPRQEFSLVFQKVKEMEKTGAHIINLGQGNPDLPTPPHIVEALREASLNPSFHGYGPFRGYPFLKEAIA
AFYKREYGVTINPETEVALFGGGKAGLYVLTQCLLNPGDIALVPNPGYPEYLSGITMARAELYEMPLYEENGYLPDFEKI
DPAVLEKAKLMFLNYPNNPTGAVADAAFYAKAAAFAKEHNIHLIHDFAYGAFEFDQKPASFLEAEDAKTVGAELYSFSKT
FNMAGWRMAFAVGNEKIIQAVNEFQDHVFVGMFGGLQQAASAALSGDPEHTESLKRIYKERIDFFTALCEKELGWKMEKP
KGTFYVWAEIPNTFETSHQFSDYLLEHAHVVVTPGEIFGSNGKRHVRISMVSKQEDLREFVTRIQKLNLPFGSLQETSR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family

Homologues:

Organism=Homo sapiens, GI56713254, Length=381, Percent_Identity=24.9343832020997, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI56713256, Length=381, Percent_Identity=24.9343832020997, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4507369, Length=410, Percent_Identity=23.1707317073171, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=22.8287841191067, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=22.8287841191067, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI149944424, Length=353, Percent_Identity=26.0623229461756, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788722, Length=394, Percent_Identity=35.7868020304569, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1786816, Length=358, Percent_Identity=24.8603351955307, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788627, Length=378, Percent_Identity=24.3386243386243, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=263, Percent_Identity=26.615969581749, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71994476, Length=263, Percent_Identity=26.615969581749, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=23.7837837837838, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=389, Percent_Identity=21.0796915167095, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=317, Percent_Identity=24.6056782334385, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI28573069, Length=380, Percent_Identity=23.4210526315789, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646114, Length=380, Percent_Identity=23.4210526315789, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573067, Length=380, Percent_Identity=23.4210526315789, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573065, Length=380, Percent_Identity=23.4210526315789, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=21.6577540106952, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AAT2_BACSU (P39643)

Other databases:

- EMBL:   X73124
- EMBL:   AL009126
- PIR:   S39740
- RefSeq:   NP_391649.1
- ProteinModelPortal:   P39643
- SMR:   P39643
- EnsemblBacteria:   EBBACT00000002926
- GeneID:   937157
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU37690
- NMPDR:   fig|224308.1.peg.3775
- GenoList:   BSU37690
- GeneTree:   EBGT00070000031804
- HOGENOM:   HBG645860
- OMA:   KGTFYVW
- PhylomeDB:   P39643
- ProtClustDB:   PRK08068
- BioCyc:   BSUB:BSU37690-MONOMER
- BRENDA:   2.6.1.1
- GO:   GO:0005737
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.1

Molecular weight: Translated: 44703; Mature: 44703

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEITPSDVIKTLPRQEFSLVFQKVKEMEKTGAHIINLGQGNPDLPTPPHIVEALREASLN
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
PSFHGYGPFRGYPFLKEAIAAFYKREYGVTINPETEVALFGGGKAGLYVLTQCLLNPGDI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCHHHHHHHHHHCCCCCE
ALVPNPGYPEYLSGITMARAELYEMPLYEENGYLPDFEKIDPAVLEKAKLMFLNYPNNPT
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHCCEEEEEEECCCCCC
GAVADAAFYAKAAAFAKEHNIHLIHDFAYGAFEFDQKPASFLEAEDAKTVGAELYSFSKT
CHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHH
FNMAGWRMAFAVGNEKIIQAVNEFQDHVFVGMFGGLQQAASAALSGDPEHTESLKRIYKE
HCCCCEEEEEEECCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RIDFFTALCEKELGWKMEKPKGTFYVWAEIPNTFETSHQFSDYLLEHAHVVVTPGEIFGS
HHHHHHHHHHHHHCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEECHHHHCC
NGKRHVRISMVSKQEDLREFVTRIQKLNLPFGSLQETSR
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHCCCC
>Mature Secondary Structure
MEITPSDVIKTLPRQEFSLVFQKVKEMEKTGAHIINLGQGNPDLPTPPHIVEALREASLN
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCC
PSFHGYGPFRGYPFLKEAIAAFYKREYGVTINPETEVALFGGGKAGLYVLTQCLLNPGDI
CCCCCCCCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCHHHHHHHHHHCCCCCE
ALVPNPGYPEYLSGITMARAELYEMPLYEENGYLPDFEKIDPAVLEKAKLMFLNYPNNPT
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHHHCCEEEEEEECCCCCC
GAVADAAFYAKAAAFAKEHNIHLIHDFAYGAFEFDQKPASFLEAEDAKTVGAELYSFSKT
CHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHH
FNMAGWRMAFAVGNEKIIQAVNEFQDHVFVGMFGGLQQAASAALSGDPEHTESLKRIYKE
HCCCCEEEEEEECCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RIDFFTALCEKELGWKMEKPKGTFYVWAEIPNTFETSHQFSDYLLEHAHVVVTPGEIFGS
HHHHHHHHHHHHHCCEEECCCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEECHHHHCC
NGKRHVRISMVSKQEDLREFVTRIQKLNLPFGSLQETSR
CCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377