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The map label for this gene is uvsE

Identifier: 16080773

GI number: 16080773

Start: 3817863

End: 3818825

Strand: Direct

Name: uvsE

Synonym: BSU37200

Alternate gene names: 16080773

Gene position: 3817863-3818825 (Clockwise)

Preceding gene: 16080772

Following gene: 16080774

Centisome position: 90.56

GC content: 46.73

Gene sequence:

>963_bases
ATGATTTTCAGATTCGGGTTCGTTTCAAATGCGATGAGCCTTTGGGATGCGTCTCCCGCTAAAACATTGACATTCGCGCG
TTATTCAAAGCTTTCAAAGACTGAAAGAAAAGAAGCGCTTCTGACTGTGACAAAAGCCAATTTGCGCAATACGATGAGAA
CCCTTCACTATATCATCGGCCACGGCATTCCTTTGTACCGTTTTTCCAGTTCGATTGTGCCGCTGGCTACGCATCCCGAC
GTGATGTGGGATTTTGTAACACCGTTTCAAAAAGAGTTTCGGGAGATTGGAGAGCTTGTTAAAACCCATCAACTGCGAAC
AAGCTTTCATCCAAATCAATTCACTCTGTTTACGAGCCCGAAGGAATCCGTCACAAAAAATGCGGTAACAGATATGGCGT
ATCACTACCGCATGCTTGAGGCCATGGGCATTGCTGATCGCTCCGTTATCAACATTCATATTGGCGGCGCTTACGGAAAT
AAAGACACCGCCACTGCACAATTTCATCAAAATATAAAACAGCTGCCGCAGGAGATCAAAGAGCGGATGACACTTGAAAA
TGATGATAAAACATATACAACGGAAGAAACGCTTCAGGTCTGTGAGCAGGAGGATGTTCCGTTTGTCTTTGACTTTCATC
ATTTTTACGCCAATCCAGACGATCACGCCGACCTGAATGTAGCACTGCCCCGCATGATCAAAACGTGGGAGCGGATCGGC
CTTCAGCCAAAGGTTCACTTGTCTTCCCCAAAATCGGAGCAAGCGATACGCAGCCACGCCGATTATGTTGACGCCAACTT
TTTGCTGCCACTGTTGGAACGCTTTAGGCAATGGGGAACTAATATTGATTTCATGATTGAAGCAAAGCAGAAAGACAAGG
CGCTTCTCCGCTTGATGGATGAATTAAGCTCCATCCGCGGTGTCAAACGCATCGGGGGCGGTGCGCTGCAATGGAAGTCA
TAA

Upstream 100 bases:

>100_bases
GCTGCTGACGATGGAGGATTTCAGCAAGCGCACATTCAGGCAGCGCCCGGCGGAATGGCTCGGCAGGGCATTATCTTATT
TCTTATAAAGGAGAGTTCCT

Downstream 100 bases:

>100_bases
ATGTGCAAAAATAGGTTTACGACTTGTCAGCTTTGGGAACTTAGGCTATATAAGACAACAATCGATGGAGGAGAAAGATC
ATGAAAAATATCAAGTCTCT

Product: UV damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSKTERKEALLTVTKANLRNTMRTLHYIIGHGIPLYRFSSSIVPLATHPD
VMWDFVTPFQKEFREIGELVKTHQLRTSFHPNQFTLFTSPKESVTKNAVTDMAYHYRMLEAMGIADRSVINIHIGGAYGN
KDTATAQFHQNIKQLPQEIKERMTLENDDKTYTTEETLQVCEQEDVPFVFDFHHFYANPDDHADLNVALPRMIKTWERIG
LQPKVHLSSPKSEQAIRSHADYVDANFLLPLLERFRQWGTNIDFMIEAKQKDKALLRLMDELSSIRGVKRIGGGALQWKS

Sequences:

>Translated_320_residues
MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSKTERKEALLTVTKANLRNTMRTLHYIIGHGIPLYRFSSSIVPLATHPD
VMWDFVTPFQKEFREIGELVKTHQLRTSFHPNQFTLFTSPKESVTKNAVTDMAYHYRMLEAMGIADRSVINIHIGGAYGN
KDTATAQFHQNIKQLPQEIKERMTLENDDKTYTTEETLQVCEQEDVPFVFDFHHFYANPDDHADLNVALPRMIKTWERIG
LQPKVHLSSPKSEQAIRSHADYVDANFLLPLLERFRQWGTNIDFMIEAKQKDKALLRLMDELSSIRGVKRIGGGALQWKS
>Mature_320_residues
MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSKTERKEALLTVTKANLRNTMRTLHYIIGHGIPLYRFSSSIVPLATHPD
VMWDFVTPFQKEFREIGELVKTHQLRTSFHPNQFTLFTSPKESVTKNAVTDMAYHYRMLEAMGIADRSVINIHIGGAYGN
KDTATAQFHQNIKQLPQEIKERMTLENDDKTYTTEETLQVCEQEDVPFVFDFHHFYANPDDHADLNVALPRMIKTWERIG
LQPKVHLSSPKSEQAIRSHADYVDANFLLPLLERFRQWGTNIDFMIEAKQKDKALLRLMDELSSIRGVKRIGGGALQWKS

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVSE_BACSU (P45864)

Other databases:

- EMBL:   Z49782
- EMBL:   AL009126
- PIR:   S55418
- RefSeq:   NP_391601.1
- ProteinModelPortal:   P45864
- SMR:   P45864
- EnsemblBacteria:   EBBACT00000002931
- GeneID:   938195
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU37200
- NMPDR:   fig|224308.1.peg.3727
- GenoList:   BSU37200
- GeneTree:   EBGT00050000002221
- HOGENOM:   HBG456662
- OMA:   KKLPAHI
- ProtClustDB:   PRK02308
- BioCyc:   BSUB:BSU37200-MONOMER
- HAMAP:   MF_00606
- InterPro:   IPR004601
- InterPro:   IPR013022
- TIGRFAMs:   TIGR00629

Pfam domain/function: PF03851 UvdE; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: NA

Molecular weight: Translated: 36897; Mature: 36897

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSKTERKEALLTVTKANLRNTMRTLHYIIG
CEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGIPLYRFSSSIVPLATHPDVMWDFVTPFQKEFREIGELVKTHQLRTSFHPNQFTLFTSP
CCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
KESVTKNAVTDMAYHYRMLEAMGIADRSVINIHIGGAYGNKDTATAQFHQNIKQLPQEIK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
ERMTLENDDKTYTTEETLQVCEQEDVPFVFDFHHFYANPDDHADLNVALPRMIKTWERIG
HHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHC
LQPKVHLSSPKSEQAIRSHADYVDANFLLPLLERFRQWGTNIDFMIEAKQKDKALLRLMD
CCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHH
ELSSIRGVKRIGGGALQWKS
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSKTERKEALLTVTKANLRNTMRTLHYIIG
CEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGIPLYRFSSSIVPLATHPDVMWDFVTPFQKEFREIGELVKTHQLRTSFHPNQFTLFTSP
CCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
KESVTKNAVTDMAYHYRMLEAMGIADRSVINIHIGGAYGNKDTATAQFHQNIKQLPQEIK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
ERMTLENDDKTYTTEETLQVCEQEDVPFVFDFHHFYANPDDHADLNVALPRMIKTWERIG
HHCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHC
LQPKVHLSSPKSEQAIRSHADYVDANFLLPLLERFRQWGTNIDFMIEAKQKDKALLRLMD
CCCEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHH
ELSSIRGVKRIGGGALQWKS
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 8614629