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The map label for this gene is cotH

Identifier: 16080659

GI number: 16080659

Start: 3716009

End: 3717097

Strand: Reverse

Name: cotH

Synonym: BSU36060

Alternate gene names: 16080659

Gene position: 3717097-3716009 (Counterclockwise)

Preceding gene: 16080663

Following gene: 16080658

Centisome position: 88.17

GC content: 40.77

Gene sequence:

>1089_bases
ATGAAGAATCAATCCAATTTACCGCTTTATCAGCTGTTTGTTCATCCAAAAGACTTGCGTGAATTAAAAAAGGATATATG
GGACGATGATCCGGTGCCAGCTGTGATGAAGGTAAATCAAAAAAGGCTGGATATTGATATCGCTTATCGGGGATCACATA
TCAGAGACTTCAAAAAGAAGTCATACCATATTTCCTTTTATCAGCCGAAAACATTCCGCGGCGCGCGAGAGATTCACTTA
AATGCGGAGTATAAAGACCCTTCCTTGATGAGAAACAAATTGTCTCTGGATTTTTTCTCGGAGCTAGGGACACTGTCTCC
AAAGGCAGAGTTTGCGTTTGTAAAGATGAATGGGAAGAATGAAGGGGTTTATCTTGAACTTGAATCCGTAGATGAATATT
ATTTGGCGAAAAGGAAGCTGGCTGATGGCGCGATTTTTTATGCGGTGGATGATGATGCCAACTTTTCTCTGATGAGCGAT
TTAGAAAGGGAAACGAAAACATCGCTGGAGCTTGGATATGAAAAGAAAACAGGGACTGAGGAAGATGATTTTTATTTACA
AGATATGATTTTTAAAATTAATACGGTCCCTAAAGCTCAGTTTAAGTCAGAAGTGACAAAACACGTGGATGTCGATAAGT
ATTTGCGCTGGCTTGCTGGTATTGTATTCACCTCGAACTATGACGGGTTTGTCCACAACTACGCATTATACAGAAGCGGG
GAAACCGGATTATTTGAGGTGATTCCTTGGGATTATGATGCGACTTGGGGCAGGGATATCCATGGAGAGCGGATGGCTGC
CGATTATGTAAGAATTCAAGGATTTAATACACTAACCGCCCGGATATTGGATGAATCCGAGTTTCGCAAGTCCTACAAGC
GCCTGTTAGAAAAAACGCTCCAATCTCTTTTTACAATAGAATATATGGAACCGAAAATCATGGCGATGTATGAACGGATT
AGGCCGTTTGTCCTCATGGACCCGTATAAAAAGAATGATATTGAGCGTTTTGACCGTGAGCCGGATGTGATCTGCGAGTA
TATTAAAAACCGTTCACAATACCTCAAAGATCATTTAAGTATTTTATGA

Upstream 100 bases:

>100_bases
CCTTACTACCCTCATAGTACGCGCGGTTTTAAAAAGTGTATAAGTGTTCCGCTGAGATCTTATAAAAATAAAAGCCTAAA
ATTTGTAAGGAGGATTATGG

Downstream 100 bases:

>100_bases
ATGCGTGAAAATGGGTATTCGCGGAAAAAGCGACAATTAGGCTATTGAATTAGTTCAACAAATAAATGTGACACGTATAT
ATGCAGTATGTTTATCATCT

Product: spore coat protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLDIDIAYRGSHIRDFKKKSYHISFYQPKTFRGAREIHL
NAEYKDPSLMRNKLSLDFFSELGTLSPKAEFAFVKMNGKNEGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSD
LERETKTSLELGYEKKTGTEEDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWLAGIVFTSNYDGFVHNYALYRSG
ETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFNTLTARILDESEFRKSYKRLLEKTLQSLFTIEYMEPKIMAMYERI
RPFVLMDPYKKNDIERFDREPDVICEYIKNRSQYLKDHLSIL

Sequences:

>Translated_362_residues
MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLDIDIAYRGSHIRDFKKKSYHISFYQPKTFRGAREIHL
NAEYKDPSLMRNKLSLDFFSELGTLSPKAEFAFVKMNGKNEGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSD
LERETKTSLELGYEKKTGTEEDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWLAGIVFTSNYDGFVHNYALYRSG
ETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFNTLTARILDESEFRKSYKRLLEKTLQSLFTIEYMEPKIMAMYERI
RPFVLMDPYKKNDIERFDREPDVICEYIKNRSQYLKDHLSIL
>Mature_362_residues
MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLDIDIAYRGSHIRDFKKKSYHISFYQPKTFRGAREIHL
NAEYKDPSLMRNKLSLDFFSELGTLSPKAEFAFVKMNGKNEGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSD
LERETKTSLELGYEKKTGTEEDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWLAGIVFTSNYDGFVHNYALYRSG
ETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFNTLTARILDESEFRKSYKRLLEKTLQSLFTIEYMEPKIMAMYERI
RPFVLMDPYKKNDIERFDREPDVICEYIKNRSQYLKDHLSIL

Specific function: Involved in the assembly of several proteins in the inner and outer layer of the spore coat. Stabilizes CotC and CotU in the mother cell compartment of sporulating cells and promotes the assembly of both early and late forms of CotC-related polypeptides o

COG id: COG5337

COG function: function code M; Spore coat assembly protein

Gene ontology:

Cell location: Spore wall, spore coat

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CotH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COTH_BACSU (Q45535)

Other databases:

- EMBL:   X98342
- EMBL:   Z93767
- EMBL:   AL009126
- EMBL:   U14964
- PIR:   E69605
- RefSeq:   NP_391487.1
- EnsemblBacteria:   EBBACT00000000917
- GeneID:   936858
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU36060
- NMPDR:   fig|224308.1.peg.3613
- GenoList:   BSU36060
- GeneTree:   EBGT00050000001774
- HOGENOM:   HBG338384
- OMA:   NENSEEQ
- ProtClustDB:   CLSK888000
- BioCyc:   BSUB:BSU36060-MONOMER
- InterPro:   IPR014867

Pfam domain/function: PF08757 CotH

EC number: NA

Molecular weight: Translated: 42813; Mature: 42813

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLDIDIAYRGSHIRDFKKK
CCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCHHHHCCCHHEEEEEEECCCHHHHHHHC
SYHISFYQPKTFRGAREIHLNAEYKDPSLMRNKLSLDFFSELGTLSPKAEFAFVKMNGKN
CEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCCCCEEEEEECCCC
EGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSDLERETKTSLELGYEKKTGTE
CCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
EDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWLAGIVFTSNYDGFVHNYALYRSG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCHHHCEEEEECC
ETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFNTLTARILDESEFRKSYKRLLEKTL
CCCEEEEECCCCCCCCCCCCCCCHHHHHEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHH
QSLFTIEYMEPKIMAMYERIRPFVLMDPYKKNDIERFDREPDVICEYIKNRSQYLKDHLS
HHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
IL
CC
>Mature Secondary Structure
MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLDIDIAYRGSHIRDFKKK
CCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCHHHHCCCHHEEEEEEECCCHHHHHHHC
SYHISFYQPKTFRGAREIHLNAEYKDPSLMRNKLSLDFFSELGTLSPKAEFAFVKMNGKN
CEEEEEECCCCCCCCEEEEEECCCCCHHHHHHHCCHHHHHHHCCCCCCCCEEEEEECCCC
EGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSDLERETKTSLELGYEKKTGTE
CCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
EDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWLAGIVFTSNYDGFVHNYALYRSG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCHHHCEEEEECC
ETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFNTLTARILDESEFRKSYKRLLEKTL
CCCEEEEECCCCCCCCCCCCCCCHHHHHEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHH
QSLFTIEYMEPKIMAMYERIRPFVLMDPYKKNDIERFDREPDVICEYIKNRSQYLKDHLS
HHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHH
IL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8755863; 8991897; 9353933; 9384377; 7814326; 10198031