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The map label for this gene is alsD

Identifier: 16080653

GI number: 16080653

Start: 3708799

End: 3709566

Strand: Reverse

Name: alsD

Synonym: BSU36000

Alternate gene names: 16080653

Gene position: 3709566-3708799 (Counterclockwise)

Preceding gene: 255767778

Following gene: 16080652

Centisome position: 88.0

GC content: 43.36

Gene sequence:

>768_bases
ATGAAACGAGAAAGCAACATTCAAGTGCTCAGCCGTGGTCAAAAAGATCAGCCTGTGAGCCAGATTTATCAAGTATCAAC
AATGACTTCTCTATTAGACGGAGTATATGACGGAGATTTTGAACTGTCAGAGATTCCGAAATATGGAGACTTCGGTATCG
GAACCTTTAACAAGCTTGACGGAGAGCTGATTGGGTTTGACGGCGAATTTTACCGTCTTCGCTCAGACGGAACCGCGACA
CCGGTCCAAAATGGAGACCGTTCACCGTTCTGTTCATTTACGTTCTTTACACCGGACATGACGCACAAAATTGATGCGAA
AATGACACGCGAAGACTTTGAAAAAGAGATCAACAGCATGCTGCCAAGCAGAAACTTATTTTATGCAATTCGCATTGACG
GATTGTTTAAAAAGGTGCAGACAAGAACAGTAGAACTTCAAGAAAAACCTTACGTGCCAATGGTTGAAGCGGTCAAAACA
CAGCCGATTTTCAACTTCGACAACGTGAGAGGAACGATTGTAGGTTTCTTGACACCAGCTTATGCAAACGGAATCGCCGT
TTCTGGCTATCACCTGCACTTCATTGACGAAGGACGCAATTCAGGCGGACACGTTTTTGACTATGTGCTTGAGGATTGCA
CGGTTACGATTTCTCAAAAAATGAACATGAATCTCAGACTTCCGAACACAGCGGATTTCTTTAATGCGAATCTGGATAAC
CCTGATTTTGCGAAAGATATCGAAACAACTGAAGGAAGCCCTGAATAA

Upstream 100 bases:

>100_bases
AAAGAATTCGGGGAACTCATGAAAACGAAAGCTCTCTAGCACTCTGCGCATCACGACACTGTTTTATGAACAGCACTAAA
TAAAAGGAGTGAAGGGAAAT

Downstream 100 bases:

>100_bases
AAGAAAAAAAGAAAGCCCCTTTTAGCAGGGCTTTCTTTTTATTTGGCTCTTTTCCTGATTTTAGATAAAATAACATCAAA
ACAGTAAAGGTGTGGTCTGA

Product: alpha-acetolactate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSEIPKYGDFGIGTFNKLDGELIGFDGEFYRLRSDGTAT
PVQNGDRSPFCSFTFFTPDMTHKIDAKMTREDFEKEINSMLPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKT
QPIFNFDNVRGTIVGFLTPAYANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTISQKMNMNLRLPNTADFFNANLDN
PDFAKDIETTEGSPE

Sequences:

>Translated_255_residues
MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSEIPKYGDFGIGTFNKLDGELIGFDGEFYRLRSDGTAT
PVQNGDRSPFCSFTFFTPDMTHKIDAKMTREDFEKEINSMLPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKT
QPIFNFDNVRGTIVGFLTPAYANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTISQKMNMNLRLPNTADFFNANLDN
PDFAKDIETTEGSPE
>Mature_255_residues
MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSEIPKYGDFGIGTFNKLDGELIGFDGEFYRLRSDGTAT
PVQNGDRSPFCSFTFFTPDMTHKIDAKMTREDFEKEINSMLPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKT
QPIFNFDNVRGTIVGFLTPAYANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTISQKMNMNLRLPNTADFFNANLDN
PDFAKDIETTEGSPE

Specific function: Converts acetolactate into acetoin, which can be excreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage

COG id: COG3527

COG function: function code Q; Alpha-acetolactate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha-acetolactate decarboxylase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALDC_BACSU (Q04777)

Other databases:

- EMBL:   L04470
- EMBL:   Z93767
- EMBL:   AL009126
- PIR:   B47126
- RefSeq:   NP_391481.1
- ProteinModelPortal:   Q04777
- SMR:   Q04777
- EnsemblBacteria:   EBBACT00000003668
- GeneID:   936857
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU36000
- NMPDR:   fig|224308.1.peg.3607
- GenoList:   BSU36000
- GeneTree:   EBGT00050000002881
- HOGENOM:   HBG364469
- OMA:   GYHLHFL
- ProtClustDB:   CLSK887995
- BioCyc:   BSUB:BSU36000-MONOMER
- BRENDA:   4.1.1.5
- InterPro:   IPR005128
- PIRSF:   PIRSF001332
- TIGRFAMs:   TIGR01252

Pfam domain/function: PF03306 AAL_decarboxy

EC number: =4.1.1.5

Molecular weight: Translated: 28800; Mature: 28800

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSEIPKYGDFGIGTFNKLD
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCC
GELIGFDGEFYRLRSDGTATPVQNGDRSPFCSFTFFTPDMTHKIDAKMTREDFEKEINSM
CEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
LPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKTQPIFNFDNVRGTIVGFLTPA
CCCCCEEEEEEECHHHHHHHHHEEEECCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECHH
YANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTISQKMNMNLRLPNTADFFNANLDN
HCCCEEECCEEEEEEECCCCCCCHHHHHHHHHHEEEEECCCCCEEECCCCHHHCCCCCCC
PDFAKDIETTEGSPE
CCHHHHCCCCCCCCC
>Mature Secondary Structure
MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSEIPKYGDFGIGTFNKLD
CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCC
GELIGFDGEFYRLRSDGTATPVQNGDRSPFCSFTFFTPDMTHKIDAKMTREDFEKEINSM
CEEEECCCCEEEEECCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
LPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKTQPIFNFDNVRGTIVGFLTPA
CCCCCEEEEEEECHHHHHHHHHEEEECCCCCCCHHHHHHCCCCCCCCCCCEEEEEEECHH
YANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTISQKMNMNLRLPNTADFFNANLDN
HCCCEEECCEEEEEEECCCCCCCHHHHHHHHHHEEEEECCCCCEEECCCCHHHCCCCCCC
PDFAKDIETTEGSPE
CCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377; 10809684