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The map label for this gene is ywrO

Identifier: 16080652

GI number: 16080652

Start: 3708172

End: 3708699

Strand: Reverse

Name: ywrO

Synonym: BSU35990

Alternate gene names: 16080652

Gene position: 3708699-3708172 (Counterclockwise)

Preceding gene: 16080653

Following gene: 255767777

Centisome position: 87.98

GC content: 45.45

Gene sequence:

>528_bases
ATGAAAATATTGGTTTTGGCAGTGCATCCTCATATGGAGACCTCAGTTGTTAATAAGGCGTGGGCTGAGGAATTGAGTAA
ACATGACAATATCACAGTACGGGATCTTTATAAGGAATACCCGGATGAAGCGATAGATGTTGCGAAGGAACAGCAGCTGT
GCGAGGAATACGATCGGATTGTCTTTCAATTCCCGCTATATTGGTACAGCTCTCCGCCGCTCTTGAAAAAATGGCAGGAT
CTTGTGCTGACTTATGGCTGGGCTTTTGGTTCAGAAGGAAATGCCTTGCATGGCAAGGAGCTGATGCTGGCTGTATCAAC
AGGGAGCGAAGCGGAAAAATATCAAGCGGGCGGAGCAAATCATTACTCGATCAGTGAGCTATTGAAACCATTTCAGGCCA
CGAGTAATCTGATCGGCATGAAGTATCTGCCTCCATATGTGTTCTATGGCGTGAATTATGCAGCTGCAGAGGATATTTCT
CACAGTGCAAAACGGTTAGCCGAATACATCCAGCAGCCTTTTGTTTAA

Upstream 100 bases:

>100_bases
AAAGAAAAAAAGAAAGCCCCTTTTAGCAGGGCTTTCTTTTTATTTGGCTCTTTTCCTGATTTTAGATAAAATAACATCAA
AACAGTAAAGGTGTGGTCTG

Downstream 100 bases:

>100_bases
AATACAGCCCTGTCCAACATACGGCAGGGCTGTATTTGTTTAAAAATCCGGCAGCTCAGACAGGTTATTTTCCTTGATGC
CGTCCGGTTCACTTCGCAAA

Product: nitroreductase

Products: NA

Alternate protein names: GSP14

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAIDVAKEQQLCEEYDRIVFQFPLYWYSSPPLLKKWQD
LVLTYGWAFGSEGNALHGKELMLAVSTGSEAEKYQAGGANHYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDIS
HSAKRLAEYIQQPFV

Sequences:

>Translated_175_residues
MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAIDVAKEQQLCEEYDRIVFQFPLYWYSSPPLLKKWQD
LVLTYGWAFGSEGNALHGKELMLAVSTGSEAEKYQAGGANHYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDIS
HSAKRLAEYIQQPFV
>Mature_175_residues
MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAIDVAKEQQLCEEYDRIVFQFPLYWYSSPPLLKKWQD
LVLTYGWAFGSEGNALHGKELMLAVSTGSEAEKYQAGGANHYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDIS
HSAKRLAEYIQQPFV

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family

Homologues:

Organism=Homo sapiens, GI156564357, Length=120, Percent_Identity=40, Blast_Score=81, Evalue=4e-16,
Organism=Escherichia coli, GI1789750, Length=173, Percent_Identity=36.9942196531792, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1786231, Length=171, Percent_Identity=38.5964912280702, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GS14_BACSU (P80871)

Other databases:

- EMBL:   Z93767
- EMBL:   AL009126
- PIR:   C70069
- RefSeq:   NP_391480.1
- ProteinModelPortal:   P80871
- SMR:   P80871
- EnsemblBacteria:   EBBACT00000003784
- GeneID:   936853
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU35990
- NMPDR:   fig|224308.1.peg.3606
- GenoList:   BSU35990
- GeneTree:   EBGT00050000000774
- HOGENOM:   HBG532247
- OMA:   PTFRINI
- PhylomeDB:   P80871
- ProtClustDB:   CLSK887994
- BioCyc:   BSUB:BSU35990-MONOMER
- InterPro:   IPR003680

Pfam domain/function: PF02525 Flavodoxin_2

EC number: 1.6.99.- [C]

Molecular weight: Translated: 19955; Mature: 19955

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAIDVAKEQQLCEEYDRI
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VFQFPLYWYSSPPLLKKWQDLVLTYGWAFGSEGNALHGKELMLAVSTGSEAEKYQAGGAN
HHHCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCC
HYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDISHSAKRLAEYIQQPFV
CCCHHHHHHHHHHHHHHCCCHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAIDVAKEQQLCEEYDRI
CEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VFQFPLYWYSSPPLLKKWQDLVLTYGWAFGSEGNALHGKELMLAVSTGSEAEKYQAGGAN
HHHCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHCCCCC
HYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDISHSAKRLAEYIQQPFV
CCCHHHHHHHHHHHHHHCCCHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377; 9298659