BacMap

Definition	Bacillus subtilis subsp. subtilis str. 168 chromosome, complete genome.
Accession	NC_000964
Length	4,215,606

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The map label for this gene is yvaG

Identifier: 16080412

GI number: 16080412

Start: 3449732

End: 3450526

Strand: Reverse

Name: yvaG

Synonym: BSU33590

Alternate gene names: 16080412

Gene position: 3450526-3449732 (Counterclockwise)

Preceding gene: 16080413

Following gene: 16080411

Centisome position: 81.85

GC content: 47.3

Gene sequence:

>795_bases
ATGAAGCTGAATTTACAAGGAAAAACCGCACTGGTGACCGGTTCGACATCAGGGATCGGAAAAGCTATTGCCTCTTCGTT
AGCTGAAGAAGGTGCGGCAGTGATCATTAACGGACGCCGGGAAGAGAAAGTGAATCAAACGATAGATGAACTGAAAACAC
AACATGCTGAAGCGGTTCTTTATCCGGCTGCATTTGATTTGGGAACAGAAGAAGGCTGCAATGAGCTGTTTCAGGCATAT
CCAGAGGTTGATATTTTGGTCAACAATTTAGGGATTTTTGAACCGGCGGAGTACTTTGATATTCCCGACGATGAATGGTT
TCGTTTTTTTGAAGTGAATATTATGAGCGGTGTAAGGCTGACACGCAGGTATTTGCATAACATGATAGAGAAAAAAGAAG
GGCGTGTGATTTTCATTGCCAGTGAAGCGGCGATTATGCCGTCACAGGAAATGGCCCATTACAGTGCGACAAAAACGATG
CAGCTGTCCATTTCCCGCAGTTTGGCGGAGCTGGCAACCGGCACGAATGTCACAGTCAACACCGTCATGCCGGGCTCTAC
CTTAACAGAGGGTGTGGAAACCATGCTGAACTCGCTGTATCCTGGTGAAAACCTGACTGTTCAAGAAGCTGAGGCACGTT
TTATGAAAGAAAACCGGCCGACATCTATTATTCAAAGACTGATCCGTCCGGAAGAAATCGCCCACTTCGTTACATTTTTA
AGCAGTCCGCTTTCCTCTGCGATCAATGGCGCGGCACTTCGGGCGGACGGCGGTTTGGTCCGCAGTGTCTTTTAA

Upstream 100 bases:

>100_bases
CATTTCAATCCCAGCTGTTTCATACTGATTGCAGAGCAGATGTTTCACCAATCAGATTTCTGTCAATAAATAAGAGGAAT
CAAAAACGGAGGGATGAATA

Downstream 100 bases:

>100_bases
ACCTCTCCCAATAGGAGAGGTTTTTTTATATATTGTTGATTTCCATAAATTTCTGCCGTATAATATTGGTACCGAAATAG
TTTTCTTGGTACCGAAAGCG

Product: oxidoreductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVLYPAAFDLGTEEGCNELFQAY
PEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMSGVRLTRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTM
QLSISRSLAELATGTNVTVNTVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHFVTFL
SSPLSSAINGAALRADGGLVRSVF

Sequences:

>Translated_264_residues
MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVLYPAAFDLGTEEGCNELFQAY
PEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMSGVRLTRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTM
QLSISRSLAELATGTNVTVNTVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHFVTFL
SSPLSSAINGAALRADGGLVRSVF
>Mature_264_residues
MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVLYPAAFDLGTEEGCNELFQAY
PEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMSGVRLTRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTM
QLSISRSLAELATGTNVTVNTVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHFVTFL
SSPLSSAINGAALRADGGLVRSVF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=30.2681992337165, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4504505, Length=215, Percent_Identity=30.2325581395349, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI7705855, Length=184, Percent_Identity=33.695652173913, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=31.6205533596838, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=27.7978339350181, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI226371731, Length=187, Percent_Identity=31.0160427807487, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=33.160621761658, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=166, Percent_Identity=33.1325301204819, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=28.125, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=29.7297297297297, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI109715829, Length=258, Percent_Identity=25.968992248062, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI4503817, Length=271, Percent_Identity=26.1992619926199, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI4557649, Length=219, Percent_Identity=28.310502283105, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI10190746, Length=215, Percent_Identity=30.2325581395349, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40807363, Length=262, Percent_Identity=24.8091603053435, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7705925, Length=260, Percent_Identity=22.3076923076923, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=24.5059288537549, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787335, Length=262, Percent_Identity=31.2977099236641, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787905, Length=263, Percent_Identity=30.0380228136882, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790717, Length=265, Percent_Identity=27.9245283018868, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=28.030303030303, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082160, Length=268, Percent_Identity=29.8507462686567, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=33.5164835164835, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=26.6409266409266, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=23.9543726235741, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=24.6212121212121, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI2367365, Length=258, Percent_Identity=27.1317829457364, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787526, Length=209, Percent_Identity=27.7511961722488, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789378, Length=197, Percent_Identity=30.9644670050761, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=31.5384615384615, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=33.4600760456274, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=27.9693486590038, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=32.5925925925926, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=32.5757575757576, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=30.9433962264151, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17568967, Length=214, Percent_Identity=28.0373831775701, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=30.5343511450382, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=29.0196078431373, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=26.9961977186312, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=31.8352059925094, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=29.6992481203008, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=28.740157480315, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=27.4809160305344, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=28.735632183908, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=26.8482490272374, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=31.5589353612167, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=28.4132841328413, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=277, Percent_Identity=28.5198555956679, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=29.3040293040293, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=208, Percent_Identity=28.8461538461538, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=27.4809160305344, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=25.8823529411765, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.2442748091603, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=210, Percent_Identity=28.0952380952381, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=27.6752767527675, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=208, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=173, Percent_Identity=30.0578034682081, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=27.6363636363636, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=29.5019157088123, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=27.9693486590038, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=272, Percent_Identity=27.2058823529412, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=267, Percent_Identity=25.0936329588015, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=30.1526717557252, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=204, Percent_Identity=27.9411764705882, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=31.8007662835249, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI21355319, Length=261, Percent_Identity=29.8850574712644, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24644339, Length=259, Percent_Identity=27.4131274131274, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI161076933, Length=186, Percent_Identity=31.7204301075269, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24584748, Length=188, Percent_Identity=31.9148936170213, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=28.4046692607004, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24584744, Length=188, Percent_Identity=30.3191489361702, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI28574402, Length=188, Percent_Identity=30.3191489361702, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI18859837, Length=214, Percent_Identity=27.1028037383178, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21358495, Length=260, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=28.8461538461538, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=27.3076923076923, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=260, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641232, Length=202, Percent_Identity=29.7029702970297, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640442, Length=201, Percent_Identity=30.8457711442786, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24640492, Length=189, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45553409, Length=197, Percent_Identity=27.4111675126904, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647948, Length=197, Percent_Identity=27.4111675126904, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647946, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YVAG_BACSU (O32229)

Other databases:

- EMBL:   AL009126
- PIR:   E70027
- RefSeq:   NP_391239.1
- HSSP:   P97852
- ProteinModelPortal:   O32229
- SMR:   O32229
- EnsemblBacteria:   EBBACT00000001225
- GeneID:   936172
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33590
- NMPDR:   fig|224308.1.peg.3365
- GenoList:   BSU33590
- GeneTree:   EBGT00070000031990
- HOGENOM:   HBG750976
- OMA:   IFIASEA
- ProtClustDB:   CLSK866510
- BioCyc:   BSUB:BSU33590-MONOMER
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081
- PRINTS:   PR00080

Pfam domain/function: PF00106 adh_short

EC number: 1.1.1.100

Molecular weight: Translated: 29009; Mature: 29009

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 154-154 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVL
CEECCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHEEE
YPAAFDLGTEEGCNELFQAYPEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMSGVRL
ECHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCCCCHHHEEEEEEEHHHHHHH
TRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTMQLSISRSLAELATGTNVTVN
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHCCCCEEEE
TVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHFVTFL
EECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHH
SSPLSSAINGAALRADGGLVRSVF
HHHHHHHHCCCEEECCCCCHHCCC
>Mature Secondary Structure
MKLNLQGKTALVTGSTSGIGKAIASSLAEEGAAVIINGRREEKVNQTIDELKTQHAEAVL
CEECCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHEEE
YPAAFDLGTEEGCNELFQAYPEVDILVNNLGIFEPAEYFDIPDDEWFRFFEVNIMSGVRL
ECHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHCCCCCHHHEEEEEEEHHHHHHH
TRRYLHNMIEKKEGRVIFIASEAAIMPSQEMAHYSATKTMQLSISRSLAELATGTNVTVN
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHEEEHHHHHHHHHHHCCCCEEEE
TVMPGSTLTEGVETMLNSLYPGENLTVQEAEARFMKENRPTSIIQRLIRPEEIAHFVTFL
EECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHH
SSPLSSAINGAALRADGGLVRSVF
HHHHHHHHCCCEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377