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The map label for this gene is bdbC

Identifier: 16080400

GI number: 16080400

Start: 3437644

End: 3438060

Strand: Reverse

Name: bdbC

Synonym: BSU33470

Alternate gene names: 16080400

Gene position: 3438060-3437644 (Counterclockwise)

Preceding gene: 16080401

Following gene: 16080399

Centisome position: 81.56

GC content: 43.65

Gene sequence:

>417_bases
ATGAAAAATAGAATCGTATTTTTATATGCTTCCTGGGTTGTGGCTCTTATCGCTATGCTGGGCAGCCTGTATTTCAGTGA
AATCAGAAAGTTTATTCCATGTGAACTGTGCTGGTACCAGCGTATCCTCATGTATCCGCTCGTCCTGATTTTAGGCATCG
CCACCTTTCAAGGGGACACACGAGTGAAAAAATATGTGCTCCCGATGGCGATTATTGGGGCATTCATTTCGATCATGCAT
TACTTAGAGCAAAAAGTGCCCGGCTTTAGCGGCATTAAGCCATGTGTCAGCGGCGTGCCGTGCTCGGGCCAATATATTAA
CTGGTTTGGTTTTATTACGATTCCATTCCTGGCCCTGATTGCTTTTATCCTGATTATCATTTTTATGTGCCTGCTGAAAG
GCGAAAAATCTGAATAA

Upstream 100 bases:

>100_bases
ACACCGACGATTTACGTCAATGATAAAGTGATCAAAAATTTTGCGGATTATGATGAAATCAAAGAGACAATAGAAAAAGA
GCTGAAAGGGAAGTAACAAT

Downstream 100 bases:

>100_bases
CAAAAAAAGCGCCCGCGTATGCCGGGCGCTTTTTTAATTTCGCAAACTCATGTCCATCAGCAATAGCCGTATTCCCTCTA
AATTTATCTTTTTTTCTCAT

Product: thiol-disulfide oxidoreductase

Products: NA

Alternate protein names: Disulfide oxidoreductase C; Thiol-disulfide oxidoreductase C

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKNRIVFLYASWVVALIAMLGSLYFSEIRKFIPCELCWYQRILMYPLVLILGIATFQGDTRVKKYVLPMAIIGAFISIMH
YLEQKVPGFSGIKPCVSGVPCSGQYINWFGFITIPFLALIAFILIIIFMCLLKGEKSE

Sequences:

>Translated_138_residues
MKNRIVFLYASWVVALIAMLGSLYFSEIRKFIPCELCWYQRILMYPLVLILGIATFQGDTRVKKYVLPMAIIGAFISIMH
YLEQKVPGFSGIKPCVSGVPCSGQYINWFGFITIPFLALIAFILIIIFMCLLKGEKSE
>Mature_138_residues
MKNRIVFLYASWVVALIAMLGSLYFSEIRKFIPCELCWYQRILMYPLVLILGIATFQGDTRVKKYVLPMAIIGAFISIMH
YLEQKVPGFSGIKPCVSGVPCSGQYINWFGFITIPFLALIAFILIIIFMCLLKGEKSE

Specific function: Required for the stabilization, possibly via formation of a disulfide bond, of the obligatory competence protein ComGC. Not normally required for production of the secreted lantibiotic sublancin 168, although it can partially substitute for BdbB when the

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family. BdbC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BDBC_BACSU (O32217)

Other databases:

- EMBL:   AL009126
- PIR:   B70041
- RefSeq:   NP_391227.1
- ProteinModelPortal:   O32217
- EnsemblBacteria:   EBBACT00000001244
- GeneID:   936042
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU33470
- NMPDR:   fig|224308.1.peg.3353
- GenoList:   BSU33470
- GeneTree:   EBGT00050000001286
- HOGENOM:   HBG313794
- OMA:   TIDICGR
- ProtClustDB:   CLSK887876
- BioCyc:   BSUB:BSU33470-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00287
- InterPro:   IPR003752
- InterPro:   IPR012187
- PIRSF:   PIRSF036659

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 15714; Mature: 15714

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1251b9dc)-; HASH(0x126f37c8)-; HASH(0x11d485a4)-; HASH(0x11aff758)-;

Cys/Met content:

3.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRIVFLYASWVVALIAMLGSLYFSEIRKFIPCELCWYQRILMYPLVLILGIATFQGDT
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
RVKKYVLPMAIIGAFISIMHYLEQKVPGFSGIKPCVSGVPCSGQYINWFGFITIPFLALI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHH
AFILIIIFMCLLKGEKSE
HHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MKNRIVFLYASWVVALIAMLGSLYFSEIRKFIPCELCWYQRILMYPLVLILGIATFQGDT
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
RVKKYVLPMAIIGAFISIMHYLEQKVPGFSGIKPCVSGVPCSGQYINWFGFITIPFLALI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHH
AFILIIIFMCLLKGEKSE
HHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 10455116; 11844773; 11744713; 11872755