Click here to switch to the map view.

The map label for this gene is tlpA

Identifier: 16080177

GI number: 16080177

Start: 3208280

End: 3210268

Strand: Reverse

Name: tlpA

Synonym: BSU31250

Alternate gene names: 16080177

Gene position: 3210268-3208280 (Counterclockwise)

Preceding gene: 255767705

Following gene: 255767704

Centisome position: 76.15

GC content: 44.24

Gene sequence:

>1989_bases
ATGAAAAAAACACTCACCACTATTCGCAGATCATCAATTGCAAGGAGACTTATTATTTCTTTCCTGCTGATCTTAATTGT
TCCGATAACCGCCCTTTCGGTTAGCGCTTATCAATCAGCAGTTGCCTCACTTGATGTACAGATGACGCAAAGCGCAAAGG
AAAATGTTCAGATATTAGATCACATCATTGATGATAAAATCAGCACTACTGAAAAAAGCCTCGCATATTTCAGCGATTGG
GCTACAGCAGAAAAATTTCAGGATAAAAAGAAAACAGAGCTGAAACAGGAATTTAAACAATTTATCCAAATGAATGATAA
TGTCGCTGCGGTATTTTCAAGCGGCAAAGACGGGGACTTCACACGTTATCCGTACGCTGACATGCCAAGCGACTTTAATG
CTTTGGAACGAGATTGGTACAAAGAAGCAATGGCCAATAAAGGCAAAACAATTGTCACTGAGCCTTATGAATCGATTTCA
TCAGGAAAAATGGTCGTCACCATCGCCCGTCAAACGGTGGATGGGTCAGGCGTTGTCGCCATTGATATGAAAATTGATGA
CTTAGTCACTACCGCGAAAGGAATCAATATCGGAAAAGAAGGCTATGCTTTTATTTTGAGCCAAAACAAGAAAGTCATCG
CCTACTCCGGAGAAAAAGCGGGAACAGAGCTAAAAGGGGACTGGGTTGATAAGCTCTACAAGGATAAAAGCGGGGACTTT
GAATATACGTACAAAGGCAAAAAGAAAAAAATGGCATTTGCAACAAGCCAAACAACAGGCTGGAAAATCAGCGGCACGAT
GTATGCAAACGAGATTCACGATGCTGCAAGCAGGGTTCTGATCATGGCTTCAATCGTTCTGGCGATTGCCATCGGAGCTG
GAATGACGGCGATTTATTTTGTGATTCGATCCATCACAAAGCCATTGAGACGCATTGTCGCATCCGCTGAAAAAATTAGT
GAAGGCGATCTAACCGAAACGATTGAAATCAATTCAAAAGATGAACTCGGCGTTCTGAGTGAGAGCTTCAATCATATGGC
ACACTCGCTTCGCTCGCTCATTCACGGGATCAAAGACTCAGTAGAACACGTTGCCTCCTCGTCTGAAGAGCTGACTGCAT
CGGCAGACCAGACAAGCAGAGCCACTGAGCACATTACGATGGCTATCGAGCAATTTTCAAACGGCAGTGAAAGCCAAAGC
GAGAAAATAGAAACGACAACCGAACAAATTAATGAAATGAATGACGGATTGGCAGAGCTGGCGCGGGCTGCAGCAGTGAT
TACAGAAACATCCGCAGATTCAACCGAAGTGTCAAGCAAAGGGGAGACACTCGTCCAGAAAACAGCCGGCCAAATGAACA
CAATTGACCATTCCGTAAAAGCAGCGGAACAAGTGGTGAAAGGGCTGGAGATCAAATCAAAGGATATCACGAATATTTTG
CGTGTCATCAACGGCATTGCGGATCAAACCAATCTTTTGGCTTTAAATGCCGCCATTGAAGCTGCCAGAGCGGGTGAATA
CGGCCGGGGCTTCTCAGTCGTCGCTGAGGAAGTGAGAAAGCTCGCGGTACAGTCGGCTGACTCAGCAAAAGAAATTGAAT
CGCTGATCAGTGAAATAGTAAAAGAAATTCACACATCACTGAACGTGCTTCAGTCCGTAAACAAAGAAGTTGAAACAGGG
CTTGTCATGACGGATGAAACTAAACAGAGCTTCAAACATATATCGCAAATGACCAATCAAATTGCTTCCGAGCTGCAAAA
CATGAATGCGACGGTTGAGGAGCTGTCAGCGGGAGCTCAAGAAATTTCCGCAGCTTCAAATGATATCACTGCCATTTCTA
AGGAAAGCTCGGATGGCATCCAAGATATCGCCGCTTCAGCTGAGGAACAGCTGGCATCCATGGAGGAGATTAGTTCATCT
GCACTGACGCTTGAAAGAATGTCTGAAGAACTCCGTGATCTGACAAAACAATTTAAAGTAGACAAATAA

Upstream 100 bases:

>100_bases
ATTTAGAACTATTTTTCATTTTTTCCTCCATTTTCAATGTAATTTAAAGGAAGATCCGCCGATATAATTTGTAAATTATT
GAAAGAAGGTTCAAAAGGAA

Downstream 100 bases:

>100_bases
TAGGTCTAAAATACTATTTATTTATGGGAAATTAGTTACTTTTGTTAAATTTCTTCTTTTTTGCTGTATATATTTACCCA
TTTCCAGCCGATATGAAGGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQSAVASLDVQMTQSAKENVQILDHIIDDKISTTEKSLAYFSDW
ATAEKFQDKKKTELKQEFKQFIQMNDNVAAVFSSGKDGDFTRYPYADMPSDFNALERDWYKEAMANKGKTIVTEPYESIS
SGKMVVTIARQTVDGSGVVAIDMKIDDLVTTAKGINIGKEGYAFILSQNKKVIAYSGEKAGTELKGDWVDKLYKDKSGDF
EYTYKGKKKKMAFATSQTTGWKISGTMYANEIHDAASRVLIMASIVLAIAIGAGMTAIYFVIRSITKPLRRIVASAEKIS
EGDLTETIEINSKDELGVLSESFNHMAHSLRSLIHGIKDSVEHVASSSEELTASADQTSRATEHITMAIEQFSNGSESQS
EKIETTTEQINEMNDGLAELARAAAVITETSADSTEVSSKGETLVQKTAGQMNTIDHSVKAAEQVVKGLEIKSKDITNIL
RVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIESLISEIVKEIHTSLNVLQSVNKEVETG
LVMTDETKQSFKHISQMTNQIASELQNMNATVEELSAGAQEISAASNDITAISKESSDGIQDIAASAEEQLASMEEISSS
ALTLERMSEELRDLTKQFKVDK

Sequences:

>Translated_662_residues
MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQSAVASLDVQMTQSAKENVQILDHIIDDKISTTEKSLAYFSDW
ATAEKFQDKKKTELKQEFKQFIQMNDNVAAVFSSGKDGDFTRYPYADMPSDFNALERDWYKEAMANKGKTIVTEPYESIS
SGKMVVTIARQTVDGSGVVAIDMKIDDLVTTAKGINIGKEGYAFILSQNKKVIAYSGEKAGTELKGDWVDKLYKDKSGDF
EYTYKGKKKKMAFATSQTTGWKISGTMYANEIHDAASRVLIMASIVLAIAIGAGMTAIYFVIRSITKPLRRIVASAEKIS
EGDLTETIEINSKDELGVLSESFNHMAHSLRSLIHGIKDSVEHVASSSEELTASADQTSRATEHITMAIEQFSNGSESQS
EKIETTTEQINEMNDGLAELARAAAVITETSADSTEVSSKGETLVQKTAGQMNTIDHSVKAAEQVVKGLEIKSKDITNIL
RVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIESLISEIVKEIHTSLNVLQSVNKEVETG
LVMTDETKQSFKHISQMTNQIASELQNMNATVEELSAGAQEISAASNDITAISKESSDGIQDIAASAEEQLASMEEISSS
ALTLERMSEELRDLTKQFKVDK
>Mature_662_residues
MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQSAVASLDVQMTQSAKENVQILDHIIDDKISTTEKSLAYFSDW
ATAEKFQDKKKTELKQEFKQFIQMNDNVAAVFSSGKDGDFTRYPYADMPSDFNALERDWYKEAMANKGKTIVTEPYESIS
SGKMVVTIARQTVDGSGVVAIDMKIDDLVTTAKGINIGKEGYAFILSQNKKVIAYSGEKAGTELKGDWVDKLYKDKSGDF
EYTYKGKKKKMAFATSQTTGWKISGTMYANEIHDAASRVLIMASIVLAIAIGAGMTAIYFVIRSITKPLRRIVASAEKIS
EGDLTETIEINSKDELGVLSESFNHMAHSLRSLIHGIKDSVEHVASSSEELTASADQTSRATEHITMAIEQFSNGSESQS
EKIETTTEQINEMNDGLAELARAAAVITETSADSTEVSSKGETLVQKTAGQMNTIDHSVKAAEQVVKGLEIKSKDITNIL
RVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIESLISEIVKEIHTSLNVLQSVNKEVETG
LVMTDETKQSFKHISQMTNQIASELQNMNATVEELSAGAQEISAASNDITAISKESSDGIQDIAASAEEQLASMEEISSS
ALTLERMSEELRDLTKQFKVDK

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain

Homologues:

Organism=Escherichia coli, GI1787690, Length=389, Percent_Identity=32.6478149100257, Blast_Score=142, Evalue=9e-35,
Organism=Escherichia coli, GI1788195, Length=319, Percent_Identity=29.4670846394984, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI2367378, Length=269, Percent_Identity=32.7137546468402, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1788194, Length=370, Percent_Identity=29.7297297297297, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789453, Length=408, Percent_Identity=25.2450980392157, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TLPA_BACSU (P39216)

Other databases:

- EMBL:   L29189
- EMBL:   AL009126
- PIR:   C54078
- RefSeq:   NP_391003.1
- ProteinModelPortal:   P39216
- EnsemblBacteria:   EBBACT00000001374
- GeneID:   938840
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31250
- NMPDR:   fig|224308.1.peg.3128
- GenoList:   BSU31250
- GeneTree:   EBGT00070000031772
- HOGENOM:   HBG338974
- OMA:   IVTEPYE
- ProtClustDB:   CLSK2301479
- BioCyc:   BSUB:BSU31250-MONOMER
- GO:   GO:0006935
- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094
- SMART:   SM00304
- SMART:   SM00283
- SMART:   SM00319

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH

EC number: NA

Molecular weight: Translated: 72278; Mature: 72278

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00538 CHEMOTAXIS_TRANSDUC_1; PS50111 CHEMOTAXIS_TRANSDUC_2; PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10b07510)-; HASH(0x11623898)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQSAVASLDVQMTQSAKENVQILD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIIDDKISTTEKSLAYFSDWATAEKFQDKKKTELKQEFKQFIQMNDNVAAVFSSGKDGDF
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
TRYPYADMPSDFNALERDWYKEAMANKGKTIVTEPYESISSGKMVVTIARQTVDGSGVVA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCEEEEEEEECCCCCCEEE
IDMKIDDLVTTAKGINIGKEGYAFILSQNKKVIAYSGEKAGTELKGDWVDKLYKDKSGDF
EEEEHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCE
EYTYKGKKKKMAFATSQTTGWKISGTMYANEIHDAASRVLIMASIVLAIAIGAGMTAIYF
EEEECCCCCEEEEEECCCCCEEEECEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VIRSITKPLRRIVASAEKISEGDLTETIEINSKDELGVLSESFNHMAHSLRSLIHGIKDS
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VEHVASSSEELTASADQTSRATEHITMAIEQFSNGSESQSEKIETTTEQINEMNDGLAEL
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ARAAAVITETSADSTEVSSKGETLVQKTAGQMNTIDHSVKAAEQVVKGLEIKSKDITNIL
HHHHHHHHCCCCCCCHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIESLISEIV
HHHHCCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KEIHTSLNVLQSVNKEVETGLVMTDETKQSFKHISQMTNQIASELQNMNATVEELSAGAQ
HHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHH
EISAASNDITAISKESSDGIQDIAASAEEQLASMEEISSSALTLERMSEELRDLTKQFKV
HHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DK
CH
>Mature Secondary Structure
MKKTLTTIRRSSIARRLIISFLLILIVPITALSVSAYQSAVASLDVQMTQSAKENVQILD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIIDDKISTTEKSLAYFSDWATAEKFQDKKKTELKQEFKQFIQMNDNVAAVFSSGKDGDF
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
TRYPYADMPSDFNALERDWYKEAMANKGKTIVTEPYESISSGKMVVTIARQTVDGSGVVA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCEEEEEEEECCCCCCEEE
IDMKIDDLVTTAKGINIGKEGYAFILSQNKKVIAYSGEKAGTELKGDWVDKLYKDKSGDF
EEEEHHHHHHHHCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCE
EYTYKGKKKKMAFATSQTTGWKISGTMYANEIHDAASRVLIMASIVLAIAIGAGMTAIYF
EEEECCCCCEEEEEECCCCCEEEECEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VIRSITKPLRRIVASAEKISEGDLTETIEINSKDELGVLSESFNHMAHSLRSLIHGIKDS
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VEHVASSSEELTASADQTSRATEHITMAIEQFSNGSESQSEKIETTTEQINEMNDGLAEL
HHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ARAAAVITETSADSTEVSSKGETLVQKTAGQMNTIDHSVKAAEQVVKGLEIKSKDITNIL
HHHHHHHHCCCCCCCHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIESLISEIV
HHHHCCCCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KEIHTSLNVLQSVNKEVETGLVMTDETKQSFKHISQMTNQIASELQNMNATVEELSAGAQ
HHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHH
EISAASNDITAISKESSDGIQDIAASAEEQLASMEEISSSALTLERMSEELRDLTKQFKV
HHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DK
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377