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The map label for this gene is ytkD

Identifier: 16080115

GI number: 16080115

Start: 3134983

End: 3135459

Strand: Reverse

Name: ytkD

Synonym: BSU30630

Alternate gene names: 16080115

Gene position: 3135459-3134983 (Counterclockwise)

Preceding gene: 16080116

Following gene: 16080110

Centisome position: 74.38

GC content: 42.98

Gene sequence:

>477_bases
ATGTACGAGTTTAAAGATTATTATCAGAATACTGTTCAGCTTTCCTTTGACGATCAGCCTTTCTCGGACAGCCCGAAGCA
TGTCTGGGTGATTTGCCGTTTTGGCGGCAAATGGCTTTTAACAGAACATGAGGACAGAGGCTATGAGTTTCCAGGCGGGA
AAGTAGAGCCGATGGAGTGCGCAGAAGAGGCTGCGCTCCGGGAAGTAAAGGAAGAGACGGGCGCGAGAGTCAAAAGCCTC
AAGTATCTCGGACAGTATAAAGTTCTCGGAAAAGAAAAAGTGATTGTAAAAAATATATATTTTGCAGATATAGAAAAGCT
TGAAAAGCAGGCTGATTACTTTGAAACGAAAGGCCCGGTTTTGTTTCACGAGCTGCCGGAGAACCTTTCCCGCAATAAAA
AATTCAGCTTTATTATGAAGGATTCCGTTCTTCCGATCAGCTTGAAAAAACTGAAAGAATCTGGATGGATTGAATAA

Upstream 100 bases:

>100_bases
CGTGCTGGGTTTCCCTTATTTTTTGATAAAAGGCTTCCGAAGAAACGTAACTGTGGTATGATGTATGGAAGATAGCTAGG
AACGGATTTGAGGGATAAAC

Downstream 100 bases:

>100_bases
AAAACCCGGCACATGTGCCGGGTTTTTTATGTCCTCCCCTTCGTCCATTTCTTTTCCAGCAGCTCGACGCCCTGATACAT
CAGAGTGGCGAAGATGGCGA

Product: nucleoside triphosphate phosphohydrolase

Products: NA

Alternate protein names: 8-oxo-dGTPase; dGTP pyrophosphohydrolase

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MYEFKDYYQNTVQLSFDDQPFSDSPKHVWVICRFGGKWLLTEHEDRGYEFPGGKVEPMECAEEAALREVKEETGARVKSL
KYLGQYKVLGKEKVIVKNIYFADIEKLEKQADYFETKGPVLFHELPENLSRNKKFSFIMKDSVLPISLKKLKESGWIE

Sequences:

>Translated_158_residues
MYEFKDYYQNTVQLSFDDQPFSDSPKHVWVICRFGGKWLLTEHEDRGYEFPGGKVEPMECAEEAALREVKEETGARVKSL
KYLGQYKVLGKEKVIVKNIYFADIEKLEKQADYFETKGPVLFHELPENLSRNKKFSFIMKDSVLPISLKKLKESGWIE
>Mature_158_residues
MYEFKDYYQNTVQLSFDDQPFSDSPKHVWVICRFGGKWLLTEHEDRGYEFPGGKVEPMECAEEAALREVKEETGARVKSL
KYLGQYKVLGKEKVIVKNIYFADIEKLEKQADYFETKGPVLFHELPENLSRNKKFSFIMKDSVLPISLKKLKESGWIE

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal effici

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YTKD_BACSU (O35013)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   E69994
- RefSeq:   NP_390941.1
- ProteinModelPortal:   O35013
- SMR:   O35013
- EnsemblBacteria:   EBBACT00000000160
- GeneID:   937072
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU30630
- NMPDR:   fig|224308.1.peg.3066
- GenoList:   BSU30630
- GeneTree:   EBGT00050000000497
- HOGENOM:   HBG314003
- OMA:   HVWVICR
- ProtClustDB:   CLSK2752485
- BioCyc:   BSUB:BSU30630-MONOMER
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR014078
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502
- TIGRFAMs:   TIGR02705

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: NA

Molecular weight: Translated: 18512; Mature: 18512

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEFKDYYQNTVQLSFDDQPFSDSPKHVWVICRFGGKWLLTEHEDRGYEFPGGKVEPMEC
CCCHHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCEEEEEECCCCCEECCCCCCCHHHH
AEEAALREVKEETGARVKSLKYLGQYKVLGKEKVIVKNIYFADIEKLEKQADYFETKGPV
HHHHHHHHHHHHHCHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
LFHELPENLSRNKKFSFIMKDSVLPISLKKLKESGWIE
EEHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MYEFKDYYQNTVQLSFDDQPFSDSPKHVWVICRFGGKWLLTEHEDRGYEFPGGKVEPMEC
CCCHHHHCCCEEEEEECCCCCCCCCCEEEEEEEECCEEEEEECCCCCEECCCCCCCHHHH
AEEAALREVKEETGARVKSLKYLGQYKVLGKEKVIVKNIYFADIEKLEKQADYFETKGPV
HHHHHHHHHHHHHCHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCE
LFHELPENLSRNKKFSFIMKDSVLPISLKKLKESGWIE
EEHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377