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The map label for this gene is nrnA

Identifier: 16079977

GI number: 16079977

Start: 2995908

End: 2996849

Strand: Reverse

Name: nrnA

Synonym: BSU29250

Alternate gene names: 16079977

Gene position: 2996849-2995908 (Counterclockwise)

Preceding gene: 16079979

Following gene: 16079975

Centisome position: 71.09

GC content: 44.9

Gene sequence:

>942_bases
ATGAAAACAGAATTGATCAGAACCATATCATTATATGACACGATTATCTTACATAGACATGTGCGTCCTGATCCGGATGC
CTACGGATCACAGTGTGGGCTTACGGAAATCCTGCGTGAAACATATCCTGAAAAAAATATTTTTGCGGTCGGCACGCCTG
AACCGTCCCTCTCTTTCTTATATTCCCTTGATGAGGTGGACAATGAAACATATGAAGGCGCACTTGTCATTGTCTGCGAT
ACGGCAAATCAGGAAAGAATCGACGATCAGCGTTATCCTTCAGGCGCCAAACTAATGAAAATCGACCACCATCCGAACGA
AGATCCATACGGTGACCTTCTCTGGGTCGATACAAGCGCCAGCTCAGTAAGTGAAATGATTTACGAGCTGTATTTAGAAG
GAAAAGAGCACGGCTGGAAGCTGAATACGAAAGCGGCAGAGCTGATCTACGCCGGCATTGTTGGAGATACCGGACGCTTT
TTATTTCCGAATACCACGGAAAAAACACTAAAATATGCAGGCGAGCTCATTCAGTATCCATTCTCTTCCTCAGAGTTATT
TAATCAATTGTATGAAACAAAACTGAATGTGGTGAAGCTTAACGGCTTTATCTTTCAAAATGTGTCTTTGTCCGAAAACG
GGGCGGCTTCTGTTTTCATCAAAAAGGATACGCTTGAAAAATTCGGCACAACGGCTTCTGAAGCGTCGCAGCTTGTCGGG
ACGCTTGGCAATATCTCAGGTATTCGCGCCTGGGTGTTTTTCGTAGAAGAAGACGATCAAATCAGAGTCAGATTCCGTTC
GAAGGGGCCTGTCATTAACGGACTTGCCCGGAAATATAACGGCGGAGGGCATCCGTTAGCTTCAGGCGCCTCTATTTACA
GCTGGGATGAAGCTGATCGTATTTTAGCTGATCTGGAAACATTATGTAAAGAACACGAGTAG

Upstream 100 bases:

>100_bases
ACCCCATTTTATACAAAAACGGGCTTGGTTTTGACGTTATTTTTCTTTTCCGTCGGCAGAGAATGTGATTTAATGAATAA
AAACAATAAAGGAGTATCAA

Downstream 100 bases:

>100_bases
AGGGGAGACCCTCTCTCTTAGTGTTCATCTGTGACGGGGATGAACCAGCAGCCGAAATCAGTAAGGTCCTCGTAGACTTG
GAGATTGTGTGATTGAAGTT

Product: oligoribonuclease (nanoRNAse), 3',5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPEKNIFAVGTPEPSLSFLYSLDEVDNETYEGALVIVCD
TANQERIDDQRYPSGAKLMKIDHHPNEDPYGDLLWVDTSASSVSEMIYELYLEGKEHGWKLNTKAAELIYAGIVGDTGRF
LFPNTTEKTLKYAGELIQYPFSSSELFNQLYETKLNVVKLNGFIFQNVSLSENGAASVFIKKDTLEKFGTTASEASQLVG
TLGNISGIRAWVFFVEEDDQIRVRFRSKGPVINGLARKYNGGGHPLASGASIYSWDEADRILADLETLCKEHE

Sequences:

>Translated_313_residues
MKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPEKNIFAVGTPEPSLSFLYSLDEVDNETYEGALVIVCD
TANQERIDDQRYPSGAKLMKIDHHPNEDPYGDLLWVDTSASSVSEMIYELYLEGKEHGWKLNTKAAELIYAGIVGDTGRF
LFPNTTEKTLKYAGELIQYPFSSSELFNQLYETKLNVVKLNGFIFQNVSLSENGAASVFIKKDTLEKFGTTASEASQLVG
TLGNISGIRAWVFFVEEDDQIRVRFRSKGPVINGLARKYNGGGHPLASGASIYSWDEADRILADLETLCKEHE
>Mature_313_residues
MKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPEKNIFAVGTPEPSLSFLYSLDEVDNETYEGALVIVCD
TANQERIDDQRYPSGAKLMKIDHHPNEDPYGDLLWVDTSASSVSEMIYELYLEGKEHGWKLNTKAAELIYAGIVGDTGRF
LFPNTTEKTLKYAGELIQYPFSSSELFNQLYETKLNVVKLNGFIFQNVSLSENGAASVFIKKDTLEKFGTTASEASQLVG
TLGNISGIRAWVFFVEEDDQIRVRFRSKGPVINGLARKYNGGGHPLASGASIYSWDEADRILADLETLCKEHE

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRNA_BACSU (O34600)

Other databases:

- EMBL:   AF008220
- EMBL:   AL009126
- PIR:   F69999
- RefSeq:   NP_390803.1
- ProteinModelPortal:   O34600
- SMR:   O34600
- EnsemblBacteria:   EBBACT00000003694
- GeneID:   935963
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU29250
- NMPDR:   fig|224308.1.peg.2928
- GenoList:   BSU29250
- GeneTree:   EBGT00050000001210
- HOGENOM:   HBG734492
- OMA:   RASFPEK
- ProtClustDB:   CLSK2301477
- BioCyc:   BSUB:BSU29250-MONOMER
- InterPro:   IPR003156
- InterPro:   IPR001667

Pfam domain/function: PF01368 DHH; PF02272 DHHA1

EC number: =3.1.3.7

Molecular weight: Translated: 35085; Mature: 35085

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPEKNIFAVGTPEPSLSFL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCHHHE
YSLDEVDNETYEGALVIVCDTANQERIDDQRYPSGAKLMKIDHHPNEDPYGDLLWVDTSA
EEHHHHCCCCCCCEEEEEECCCCCHHCCHHCCCCCCEEEEECCCCCCCCCCCEEEEECCH
SSVSEMIYELYLEGKEHGWKLNTKAAELIYAGIVGDTGRFLFPNTTEKTLKYAGELIQYP
HHHHHHHHHHHHCCCCCCEEECCHHEEEEEEEEECCCCCEECCCCHHHHHHHHHHHHHCC
FSSSELFNQLYETKLNVVKLNGFIFQNVSLSENGAASVFIKKDTLEKFGTTASEASQLVG
CCHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHH
TLGNISGIRAWVFFVEEDDQIRVRFRSKGPVINGLARKYNGGGHPLASGASIYSWDEADR
HHCCCCCEEEEEEEEECCCEEEEEEECCCCEEHHHHHHCCCCCCCCCCCCCEEECCHHHH
ILADLETLCKEHE
HHHHHHHHHHCCC
>Mature Secondary Structure
MKTELIRTISLYDTIILHRHVRPDPDAYGSQCGLTEILRETYPEKNIFAVGTPEPSLSFL
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCHHHE
YSLDEVDNETYEGALVIVCDTANQERIDDQRYPSGAKLMKIDHHPNEDPYGDLLWVDTSA
EEHHHHCCCCCCCEEEEEECCCCCHHCCHHCCCCCCEEEEECCCCCCCCCCCEEEEECCH
SSVSEMIYELYLEGKEHGWKLNTKAAELIYAGIVGDTGRFLFPNTTEKTLKYAGELIQYP
HHHHHHHHHHHHCCCCCCEEECCHHEEEEEEEEECCCCCEECCCCHHHHHHHHHHHHHCC
FSSSELFNQLYETKLNVVKLNGFIFQNVSLSENGAASVFIKKDTLEKFGTTASEASQLVG
CCHHHHHHHHHHCCCCEEEECCEEEECCCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHH
TLGNISGIRAWVFFVEEDDQIRVRFRSKGPVINGLARKYNGGGHPLASGASIYSWDEADR
HHCCCCCEEEEEEEEECCCEEEEEEECCCCEEHHHHHHCCCCCCCCCCCCCEEECCHHHH
ILADLETLCKEHE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377