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The map label for this gene is bltR

Identifier: 16079711

GI number: 16079711

Start: 2716035

End: 2716856

Strand: Reverse

Name: bltR

Synonym: BSU26580

Alternate gene names: 16079711

Gene position: 2716856-2716035 (Counterclockwise)

Preceding gene: 16079714

Following gene: 16079710

Centisome position: 64.45

GC content: 34.18

Gene sequence:

>822_bases
ATGAGCGAAGATGTTAAGAAGTATTTCACAACAGGGGAGTTTTCGAAGCTCTGCCGTGTAAAAAAACAAACTTTATTTCA
TTATGATGAGATTGGTCTTTTCTCGCCGGAAATAAAAAAAGAAAATGGGTATAGATATTATTCCTATCATCAATTTGAGA
CTTTTCAAGTCATCAGTCTATTTAAAGAGCTTGGGGTTCCATTAAAAGAAATAAAGTGTCTAATAAAAGGAAAAACACCA
GACAAGATCCTGCATGTTCTAAAAGAAAAGTCTATTGAGATTGATAAAAAAATAAATGAGCTTAAGCAGTTGCAAACGAT
CTTACAAACAAAAGTGACGCTTACAGAACAAGCACTTGAGACTGATTTTTCCTCAATTTCTTTTGAATATTTAAATGAAG
AAACATTCATGTTAAGCCGAAAAACATTAAACTTACCAGAACGAAAATATGTGGCAGCCATTTCAGAACTCATTCATGAA
GTTCAGCAATATGAATTAGATGAAGGATATCCGATAGGCGGAATCTTTGCACGGGAACAAATCTTAGAAAAAGACTTCTA
CAATTACAGTTACTTTTATATAAAAGTAAAAGATGGGGCAGAGAACATAAATTATCATGTACGGCCAAAAGGCCTGTATG
CAGTTGGATATGAAATAGGCGGAAATACTGAAGAGGCGTACCGGAGAATCATTGAGTTCATTGAAAGAAATGGAATGCAA
ATAGGGGAAAATGCATATGAGGAATATATGCTGGATGAGATGGTAGTTGACGGGTATGAAAATACATATGCAAAAATCCT
CCTTCAAGTTAAAGAGGTGTAA

Upstream 100 bases:

>100_bases
CTCAATTGAACCCTTTTTACCTATCCTTTTCGCTTGAAGCTTTTTTCAAGTACAATCAAATCATAAGGTATATGGTTACC
GTATAGTCAAGGAGGTTTTT

Downstream 100 bases:

>100_bases
AATTACGAGATTTTCATATGGAAAATTGTTTCTGTTGTGTGCCCAAAAAGAATATAAACTGGTTTACTAAAAGCGAGCCC
ACATACAGGAGACGGTACAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSEDVKKYFTTGEFSKLCRVKKQTLFHYDEIGLFSPEIKKENGYRYYSYHQFETFQVISLFKELGVPLKEIKCLIKGKTP
DKILHVLKEKSIEIDKKINELKQLQTILQTKVTLTEQALETDFSSISFEYLNEETFMLSRKTLNLPERKYVAAISELIHE
VQQYELDEGYPIGGIFAREQILEKDFYNYSYFYIKVKDGAENINYHVRPKGLYAVGYEIGGNTEEAYRRIIEFIERNGMQ
IGENAYEEYMLDEMVVDGYENTYAKILLQVKEV

Sequences:

>Translated_273_residues
MSEDVKKYFTTGEFSKLCRVKKQTLFHYDEIGLFSPEIKKENGYRYYSYHQFETFQVISLFKELGVPLKEIKCLIKGKTP
DKILHVLKEKSIEIDKKINELKQLQTILQTKVTLTEQALETDFSSISFEYLNEETFMLSRKTLNLPERKYVAAISELIHE
VQQYELDEGYPIGGIFAREQILEKDFYNYSYFYIKVKDGAENINYHVRPKGLYAVGYEIGGNTEEAYRRIIEFIERNGMQ
IGENAYEEYMLDEMVVDGYENTYAKILLQVKEV
>Mature_272_residues
SEDVKKYFTTGEFSKLCRVKKQTLFHYDEIGLFSPEIKKENGYRYYSYHQFETFQVISLFKELGVPLKEIKCLIKGKTPD
KILHVLKEKSIEIDKKINELKQLQTILQTKVTLTEQALETDFSSISFEYLNEETFMLSRKTLNLPERKYVAAISELIHEV
QQYELDEGYPIGGIFAREQILEKDFYNYSYFYIKVKDGAENINYHVRPKGLYAVGYEIGGNTEEAYRRIIEFIERNGMQI
GENAYEEYMLDEMVVDGYENTYAKILLQVKEV

Specific function: Activates transcription of the blt gene in response to structurally dissimilar drugs

COG id: COG4978

COG function: function code KT; Transcriptional regulator, effector-binding domain/component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BLTR_BACSU (P39842)

Other databases:

- EMBL:   L32599
- EMBL:   D84432
- EMBL:   AL009126
- PIR:   I39791
- RefSeq:   NP_390535.1
- ProteinModelPortal:   P39842
- SMR:   P39842
- EnsemblBacteria:   EBBACT00000000753
- GeneID:   937644
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU26580
- NMPDR:   fig|224308.1.peg.2660
- GenoList:   BSU26580
- GeneTree:   EBGT00050000001457
- HOGENOM:   HBG422396
- OMA:   KENGYRY
- ProtClustDB:   CLSK887631
- BioCyc:   BSUB:BSU26580-MONOMER
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011256
- InterPro:   IPR015358
- SMART:   SM00422

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; SSF55136 Bac_reg_effector; SSF46955 Putativ_DNA_bind

EC number: NA

Molecular weight: Translated: 32173; Mature: 32042

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00552 HTH_MERR_1; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDVKKYFTTGEFSKLCRVKKQTLFHYDEIGLFSPEIKKENGYRYYSYHQFETFQVISL
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHH
FKELGVPLKEIKCLIKGKTPDKILHVLKEKSIEIDKKINELKQLQTILQTKVTLTEQALE
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDFSSISFEYLNEETFMLSRKTLNLPERKYVAAISELIHEVQQYELDEGYPIGGIFAREQ
HHHHHHHHHHHCCHHHEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ILEKDFYNYSYFYIKVKDGAENINYHVRPKGLYAVGYEIGGNTEEAYRRIIEFIERNGMQ
HHHHHCCCEEEEEEEEECCCCCCCEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCC
IGENAYEEYMLDEMVVDGYENTYAKILLQVKEV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SEDVKKYFTTGEFSKLCRVKKQTLFHYDEIGLFSPEIKKENGYRYYSYHQFETFQVISL
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCHHHHHHHHH
FKELGVPLKEIKCLIKGKTPDKILHVLKEKSIEIDKKINELKQLQTILQTKVTLTEQALE
HHHHCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDFSSISFEYLNEETFMLSRKTLNLPERKYVAAISELIHEVQQYELDEGYPIGGIFAREQ
HHHHHHHHHHHCCHHHEEEHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
ILEKDFYNYSYFYIKVKDGAENINYHVRPKGLYAVGYEIGGNTEEAYRRIIEFIERNGMQ
HHHHHCCCEEEEEEEEECCCCCCCEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCC
IGENAYEEYMLDEMVVDGYENTYAKILLQVKEV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7608059; 8969508; 9384377