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The map label for this gene is yrkP

Identifier: 16079696

GI number: 16079696

Start: 2704435

End: 2705130

Strand: Reverse

Name: yrkP

Synonym: BSU26430

Alternate gene names: 16079696

Gene position: 2705130-2704435 (Counterclockwise)

Preceding gene: 255767611

Following gene: 16079695

Centisome position: 64.17

GC content: 42.82

Gene sequence:

>696_bases
ATGGCCTATCGAATATTAGTCGTAGAGGATGATGAGGATATTGGTGATCTTTTGGAGGAATCCCTTACACGTGCAGGTTA
CGAGGTGCTAAGAGCCAAGGATGGAAAGCGAGCATTGCAACTTGTGAATGACTCGCTTGATTTGGTTATTTTGGATATTA
TGATGCCAGGCATTTCGGGAATTGAAACATGTCAGCACATCAGGAAATCCTCTAACGTCCCGATTCTGTTTCTGACGGCC
AGATCGAGTACACTCGATAAAACTGAGGGATTACTCGCCGGCGGCGATGATTATATGACTAAACCATTCTCGGAAGAGGA
ACTTCACGCTAGAGTGATTGCTCAATTACGCAGATATACTATCTATCAGGAAAAGAAGGAACAGGAAGAAACATTTCTTA
TCGGGGGCAAACTAAGAGTGAGCGAAGAATTTAATGAGGTGTGGAAAGAGGAGAAGCAAATCAAGTTGTCAGATCTGGAG
TATCGTATCCTGAAACTTCTGATGAACAAACGCAACAAAATATTTTCTGCCCAAAATATATATGAGAGTGTGTGGGGACA
GCCTTACTTTTACTGTTCCAACAATACGGTGATGGTGCATATACGGAAGCTGCGCTCCAAAATTGAGGATGATCCGGCAC
GTCCGGTTTATATAAAAACTGAATGGGGAAGAGGATATCGATTTGGCGCATCTTAA

Upstream 100 bases:

>100_bases
TTAAGATTTACGTAGTATCTTATAACGTACTTATTACTATGAACGATATATAGTAAGGACACACGAGAAATAACAACAAG
AATCATGAGGTGAGAGAGAC

Downstream 100 bases:

>100_bases
ATTTACGCTAACCAAAAAACTGGCTTTGCTGATAATGGTTGCTGCGATTGTGAGTGGTGTGATCTTTCTGACGTTGCAAA
AGATCACAGATGATCTGATC

Product: two-component response regulator YrkQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MAYRILVVEDDEDIGDLLEESLTRAGYEVLRAKDGKRALQLVNDSLDLVILDIMMPGISGIETCQHIRKSSNVPILFLTA
RSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYTIYQEKKEQEETFLIGGKLRVSEEFNEVWKEEKQIKLSDLE
YRILKLLMNKRNKIFSAQNIYESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGAS

Sequences:

>Translated_231_residues
MAYRILVVEDDEDIGDLLEESLTRAGYEVLRAKDGKRALQLVNDSLDLVILDIMMPGISGIETCQHIRKSSNVPILFLTA
RSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYTIYQEKKEQEETFLIGGKLRVSEEFNEVWKEEKQIKLSDLE
YRILKLLMNKRNKIFSAQNIYESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGAS
>Mature_230_residues
AYRILVVEDDEDIGDLLEESLTRAGYEVLRAKDGKRALQLVNDSLDLVILDIMMPGISGIETCQHIRKSSNVPILFLTAR
SSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYTIYQEKKEQEETFLIGGKLRVSEEFNEVWKEEKQIKLSDLEY
RILKLLMNKRNKIFSAQNIYESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGAS

Specific function: Member of the two-component regulatory system yrkQ/yrkP

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=35.3711790393013, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=34.6153846153846, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=37.280701754386, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=35.3711790393013, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=33.7777777777778, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=35.1111111111111, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=32.7510917030568, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=31.858407079646, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790552, Length=237, Percent_Identity=35.4430379746835, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=32.7433628318584, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1789402, Length=232, Percent_Identity=31.8965517241379, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=33.0396475770925, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=30.3418803418803, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=28.0172413793103, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788550, Length=160, Percent_Identity=28.75, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=37.037037037037, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787487, Length=132, Percent_Identity=31.0606060606061, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YRKP_BACSU (P54443)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   F69977
- RefSeq:   NP_390520.1
- ProteinModelPortal:   P54443
- SMR:   P54443
- EnsemblBacteria:   EBBACT00000000756
- GeneID:   937663
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU26430
- NMPDR:   fig|224308.1.peg.2645
- GenoList:   BSU26430
- GeneTree:   EBGT00070000031966
- HOGENOM:   HBG753323
- OMA:   IEDDPAR
- ProtClustDB:   CLSK887622
- BioCyc:   BSUB:BSU26430-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 26795; Mature: 26664

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYRILVVEDDEDIGDLLEESLTRAGYEVLRAKDGKRALQLVNDSLDLVILDIMMPGISG
CEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHEEEEEHHHCCCCH
IETCQHIRKSSNVPILFLTARSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYT
HHHHHHHHHCCCCCEEEEECCCCCCHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
IYQEKKEQEETFLIGGKLRVSEEFNEVWKEEKQIKLSDLEYRILKLLMNKRNKIFSAQNI
HHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHH
YESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGAS
HHHHCCCEEEEECCCEEEEEHHHHHHHHCCCCCCEEEEEECCCCCEECCCC
>Mature Secondary Structure 
AYRILVVEDDEDIGDLLEESLTRAGYEVLRAKDGKRALQLVNDSLDLVILDIMMPGISG
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHEEEEEHHHCCCCH
IETCQHIRKSSNVPILFLTARSSTLDKTEGLLAGGDDYMTKPFSEEELHARVIAQLRRYT
HHHHHHHHHCCCCCEEEEECCCCCCHHHCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
IYQEKKEQEETFLIGGKLRVSEEFNEVWKEEKQIKLSDLEYRILKLLMNKRNKIFSAQNI
HHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHH
YESVWGQPYFYCSNNTVMVHIRKLRSKIEDDPARPVYIKTEWGRGYRFGAS
HHHHCCCEEEEECCCEEEEEHHHHHHHHCCCCCCEEEEEECCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377