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The map label for this gene is yrkQ

Identifier: 16079695

GI number: 16079695

Start: 2703150

End: 2704448

Strand: Reverse

Name: yrkQ

Synonym: BSU26420

Alternate gene names: 16079695

Gene position: 2704448-2703150 (Counterclockwise)

Preceding gene: 16079696

Following gene: 255767610

Centisome position: 64.15

GC content: 42.26

Gene sequence:

>1299_bases
TTGGCGCATCTTAAATTTACGCTAACCAAAAAACTGGCTTTGCTGATAATGGTTGCTGCGATTGTGAGTGGTGTGATCTT
TCTGACGTTGCAAAAGATCACAGATGATCTGATCGAGGGATATCTGAGTTCGGAAGAGTATTATCACGAGGAGTCAGCAA
GATACATTCAAAAATTCAGCAAGTACGTTTCAGAAAATGAGTTGTCTACATCAGATAGAAAAGCGTTTGGCGAGTGGGTC
AAAAAAGAAAATTACATTAACCTCACCATATTCAAGGATCAGGAGCTGCAATATGATTCTATTTATTCCGAATCGGATTA
TGGAAAGGAAAAGCTGACTCAGTACGCTCAAAATCATTCACATCCTGTCAAGTTTAGCGATGGTGAAGGACGAGTCATTA
TCGACGGTTTCTACTCTTCCCGATATTATGATCTGGCCTTTGCATTGGATTTGCTCGGGGCAACCCTCATCTTTTTAATC
ATTGTTCTCTTCGGAATTCGCCAAAGTCTTCGCTACCTTAAAACGATTCATCAAGAGATTCATATTCTTGAAGGGGGCGA
ACTGGACTACGAGATGACGATAAAAGGGCATGATGAATTAGCGATGATTGCAAAGAGCATTGAGGATCTGCGGAAAGCTT
TCCTGGATAAACTTAAAGCTATCGAGGAATTGCAAGCTGAGAGCCGCAGCCTGGTTACCGAAATGTCGCACGATATGCGC
ACACCGCTGACGTCGCTGATCATGAATCTGGAGTTTGCCAAAAAAGAGGGAGGCGAAGCGGGTGCCAGCAAAGATCGGTA
TGTAGCCAATGCTTATGGTAAAGCACTGCAATTAAAAAGCTTGTCTGACAATCTGTTTGCGTATTTCCTGCTGAACAAGG
AATATGAGGCCGATCTGGAGACCGTTGCAGTGAAAGAAGTGATCTACGATCTAATATCAGATCAGATTGCTATCCTTCAT
CAGGAGCATTTTCGGGTCCATATTTCAGGCGAGCTGCCGGAAACCTATATTAACGTGAATTTGGAGGAGCTTGGTCGTGT
ATTTGATAATGTGATGTCAAACTTATTGAAATACGCAGATCCGGAAGAAAAAATCAGTATCACGTTTGTATCGGATCAAG
AGATATTTGAGATCCATGTTAGCAATACGATTAAACTTGCAGATATAACACCGGAAAGCAACGGACTCGGTGAAAGAAGC
ATTGCGCGAATGATGTCCCGCATGCAGGGACAGTTTCACAGTATACAAAAGAATTCTAAGTACTACATTGTGCTACGATT
TTGGAACACCAAGATGTAG

Upstream 100 bases:

>100_bases
AATACGGTGATGGTGCATATACGGAAGCTGCGCTCCAAAATTGAGGATGATCCGGCACGTCCGGTTTATATAAAAACTGA
ATGGGGAAGAGGATATCGAT

Downstream 100 bases:

>100_bases
GCTGAGAATAAAAACCACGAATATATTGAAATAGGAGACAACATGATGAGATTTTCTAACAAATTCAAAAAGGTGCCTTA
CCTGTTACAAGCGCTTCTCA

Product: two-component sensor histidine kinase YrkP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MAHLKFTLTKKLALLIMVAAIVSGVIFLTLQKITDDLIEGYLSSEEYYHEESARYIQKFSKYVSENELSTSDRKAFGEWV
KKENYINLTIFKDQELQYDSIYSESDYGKEKLTQYAQNHSHPVKFSDGEGRVIIDGFYSSRYYDLAFALDLLGATLIFLI
IVLFGIRQSLRYLKTIHQEIHILEGGELDYEMTIKGHDELAMIAKSIEDLRKAFLDKLKAIEELQAESRSLVTEMSHDMR
TPLTSLIMNLEFAKKEGGEAGASKDRYVANAYGKALQLKSLSDNLFAYFLLNKEYEADLETVAVKEVIYDLISDQIAILH
QEHFRVHISGELPETYINVNLEELGRVFDNVMSNLLKYADPEEKISITFVSDQEIFEIHVSNTIKLADITPESNGLGERS
IARMMSRMQGQFHSIQKNSKYYIVLRFWNTKM

Sequences:

>Translated_432_residues
MAHLKFTLTKKLALLIMVAAIVSGVIFLTLQKITDDLIEGYLSSEEYYHEESARYIQKFSKYVSENELSTSDRKAFGEWV
KKENYINLTIFKDQELQYDSIYSESDYGKEKLTQYAQNHSHPVKFSDGEGRVIIDGFYSSRYYDLAFALDLLGATLIFLI
IVLFGIRQSLRYLKTIHQEIHILEGGELDYEMTIKGHDELAMIAKSIEDLRKAFLDKLKAIEELQAESRSLVTEMSHDMR
TPLTSLIMNLEFAKKEGGEAGASKDRYVANAYGKALQLKSLSDNLFAYFLLNKEYEADLETVAVKEVIYDLISDQIAILH
QEHFRVHISGELPETYINVNLEELGRVFDNVMSNLLKYADPEEKISITFVSDQEIFEIHVSNTIKLADITPESNGLGERS
IARMMSRMQGQFHSIQKNSKYYIVLRFWNTKM
>Mature_431_residues
AHLKFTLTKKLALLIMVAAIVSGVIFLTLQKITDDLIEGYLSSEEYYHEESARYIQKFSKYVSENELSTSDRKAFGEWVK
KENYINLTIFKDQELQYDSIYSESDYGKEKLTQYAQNHSHPVKFSDGEGRVIIDGFYSSRYYDLAFALDLLGATLIFLII
VLFGIRQSLRYLKTIHQEIHILEGGELDYEMTIKGHDELAMIAKSIEDLRKAFLDKLKAIEELQAESRSLVTEMSHDMRT
PLTSLIMNLEFAKKEGGEAGASKDRYVANAYGKALQLKSLSDNLFAYFLLNKEYEADLETVAVKEVIYDLISDQIAILHQ
EHFRVHISGELPETYINVNLEELGRVFDNVMSNLLKYADPEEKISITFVSDQEIFEIHVSNTIKLADITPESNGLGERSI
ARMMSRMQGQFHSIQKNSKYYIVLRFWNTKM

Specific function: Member of the two-component regulatory system yrkQ/yrkP. Probably activates yrkP by phosphorylation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YRKQ_BACSU (P54444)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- PIR:   G69977
- RefSeq:   NP_390519.1
- ProteinModelPortal:   P54444
- SMR:   P54444
- EnsemblBacteria:   EBBACT00000001945
- GeneID:   937662
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU26420
- NMPDR:   fig|224308.1.peg.2644
- GenoList:   BSU26420
- GeneTree:   EBGT00050000000007
- HOGENOM:   HBG338191
- OMA:   ELAMIAK
- ProtClustDB:   CLSK887621
- BioCyc:   BSUB:BSU26420-MONOMER
- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR003661
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF00672 HAMP; PF00512 HisKA; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 49723; Mature: 49592

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10138d60)-; HASH(0xf6cc950)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLKFTLTKKLALLIMVAAIVSGVIFLTLQKITDDLIEGYLSSEEYYHEESARYIQKFS
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KYVSENELSTSDRKAFGEWVKKENYINLTIFKDQELQYDSIYSESDYGKEKLTQYAQNHS
HHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHCCC
HPVKFSDGEGRVIIDGFYSSRYYDLAFALDLLGATLIFLIIVLFGIRQSLRYLKTIHQEI
CCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HILEGGELDYEMTIKGHDELAMIAKSIEDLRKAFLDKLKAIEELQAESRSLVTEMSHDMR
EEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLTSLIMNLEFAKKEGGEAGASKDRYVANAYGKALQLKSLSDNLFAYFLLNKEYEADLE
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCEEEECCCCCEEEEEEECCCHHHHHH
TVAVKEVIYDLISDQIAILHQEHFRVHISGELPETYINVNLEELGRVFDNVMSNLLKYAD
HHHHHHHHHHHHHHHHHHEEHHHEEEEEECCCCCHHEECCHHHHHHHHHHHHHHHHHHCC
PEEKISITFVSDQEIFEIHVSNTIKLADITPESNGLGERSIARMMSRMQGQFHSIQKNSK
CCCCEEEEEECCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
YYIVLRFWNTKM
EEEEEEECCCCH
>Mature Secondary Structure 
AHLKFTLTKKLALLIMVAAIVSGVIFLTLQKITDDLIEGYLSSEEYYHEESARYIQKFS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KYVSENELSTSDRKAFGEWVKKENYINLTIFKDQELQYDSIYSESDYGKEKLTQYAQNHS
HHHHCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHCCC
HPVKFSDGEGRVIIDGFYSSRYYDLAFALDLLGATLIFLIIVLFGIRQSLRYLKTIHQEI
CCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HILEGGELDYEMTIKGHDELAMIAKSIEDLRKAFLDKLKAIEELQAESRSLVTEMSHDMR
EEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TPLTSLIMNLEFAKKEGGEAGASKDRYVANAYGKALQLKSLSDNLFAYFLLNKEYEADLE
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCEEEECCCCCEEEEEEECCCHHHHHH
TVAVKEVIYDLISDQIAILHQEHFRVHISGELPETYINVNLEELGRVFDNVMSNLLKYAD
HHHHHHHHHHHHHHHHHHEEHHHEEEEEECCCCCHHEECCHHHHHHHHHHHHHHHHHHCC
PEEKISITFVSDQEIFEIHVSNTIKLADITPESNGLGERSIARMMSRMQGQFHSIQKNSK
CCCCEEEEEECCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
YYIVLRFWNTKM
EEEEEEECCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377