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The map label for this gene is yqxL

Identifier: 16079530

GI number: 16079530

Start: 2560489

End: 2561442

Strand: Reverse

Name: yqxL

Synonym: BSU24740

Alternate gene names: 16079530

Gene position: 2561442-2560489 (Counterclockwise)

Preceding gene: 255767554

Following gene: 16079529

Centisome position: 60.76

GC content: 39.31

Gene sequence:

>954_bases
ATGAAGGCACATACGGGAAAGGATTGGTTTTGGTACCAAATGGGGCCTCAAGAAAGAAGTAAGGCAAGAGATCTAATCCA
TTTTTCTCACTGGCCTCAGTGTGAAAAGTGGTTTGAAAATAACCATCACGTTAATTTTTTGCGAGTAGATACAACTGAAA
CGGAAAATGAAGCAGTATTTGGGTCGATTGTTTATGATCAGGGGCTTGGTGAAGAAAAAGACCATACTGTTTTTCACTTT
TATATCACCAGACAATATTTTTTTACAATCAACTTTGACTTTTCAATTTTGAGAGAGATTAAAGGCAAAGAAGTTGTTCG
GCAAATGGAAAGAGCGGACAATGCGATAGAGGGGTTTTTAATTCTTCTCGGCGAACTAATGAATGCGTATTTAATCGGTG
TTGATGAATTTGAAGTCAAGCTGAGAAAGCTCAGATGGCAAATTAAAGACGACAATAGCAAAAGCATTTTAAACCGCGTC
CATCTCCTGCGCCATGAACTGATGATTTGGAAAAATTTGATATTAAGCGCTAAAAAAATTGAAATGGCGTTGAAAGAAAC
CTTTTTACCTCAAAATGAAGGGAAAAAGGATTATCAGCGGACACAACTGAAGATTGACAGGGGATTTACATACATCAGCG
AATTTGAAGGGGAGCTTAACAATCTGCTGCATTCAGAGGAAGTCATTACCTCACATAGGGGGAATGAAATTGTAAAAGCG
CTGACCATTTTCACGACGCTTTTTACTCCGATTACAGCTCTGGGTGCCTTATGGGGGATGAACTTTTCAGTGATGCCGGA
ACTGAATTGGAAATACGGATATCTCTTTTCCCTCTTATTGATTGTCACATCTACAGTTCTGATCTATCTCTATTTGAGAA
AAAAAGGCTGGACGGGAGATATGCTGCAGGAGCGGAAGAAGAAAAAGAAACCTCGAAAAAGGCGGACTCTATAG

Upstream 100 bases:

>100_bases
GAAAATGCTCATAAAACATGTGTTGAAGCGGCAGACTGGTTTAGTGACGCGGTTATTGGGCAATTAAAGAATAAAGAACA
AAAGTTTGGAGGAGCTTGAC

Downstream 100 bases:

>100_bases
GATGTTTCATATTTTGTGCAGCGTGCCCCGCTTTTTCACCAGACATATCAGGGTGACCGGATACGATGTCAAGGGGCTTA
TGACAGAGCATTAAATCCGC

Product: CorA-type Mg(2+) transporter

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKAHTGKDWFWYQMGPQERSKARDLIHFSHWPQCEKWFENNHHVNFLRVDTTETENEAVFGSIVYDQGLGEEKDHTVFHF
YITRQYFFTINFDFSILREIKGKEVVRQMERADNAIEGFLILLGELMNAYLIGVDEFEVKLRKLRWQIKDDNSKSILNRV
HLLRHELMIWKNLILSAKKIEMALKETFLPQNEGKKDYQRTQLKIDRGFTYISEFEGELNNLLHSEEVITSHRGNEIVKA
LTIFTTLFTPITALGALWGMNFSVMPELNWKYGYLFSLLLIVTSTVLIYLYLRKKGWTGDMLQERKKKKKPRKRRTL

Sequences:

>Translated_317_residues
MKAHTGKDWFWYQMGPQERSKARDLIHFSHWPQCEKWFENNHHVNFLRVDTTETENEAVFGSIVYDQGLGEEKDHTVFHF
YITRQYFFTINFDFSILREIKGKEVVRQMERADNAIEGFLILLGELMNAYLIGVDEFEVKLRKLRWQIKDDNSKSILNRV
HLLRHELMIWKNLILSAKKIEMALKETFLPQNEGKKDYQRTQLKIDRGFTYISEFEGELNNLLHSEEVITSHRGNEIVKA
LTIFTTLFTPITALGALWGMNFSVMPELNWKYGYLFSLLLIVTSTVLIYLYLRKKGWTGDMLQERKKKKKPRKRRTL
>Mature_317_residues
MKAHTGKDWFWYQMGPQERSKARDLIHFSHWPQCEKWFENNHHVNFLRVDTTETENEAVFGSIVYDQGLGEEKDHTVFHF
YITRQYFFTINFDFSILREIKGKEVVRQMERADNAIEGFLILLGELMNAYLIGVDEFEVKLRKLRWQIKDDNSKSILNRV
HLLRHELMIWKNLILSAKKIEMALKETFLPQNEGKKDYQRTQLKIDRGFTYISEFEGELNNLLHSEEVITSHRGNEIVKA
LTIFTTLFTPITALGALWGMNFSVMPELNWKYGYLFSLLLIVTSTVLIYLYLRKKGWTGDMLQERKKKKKPRKRRTL

Specific function: Mediates influx of magnesium ions

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family

Homologues:

Organism=Escherichia coli, GI2367297, Length=220, Percent_Identity=24.0909090909091, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CORA_BACSU (P40948)

Other databases:

- EMBL:   D84432
- EMBL:   AL009126
- EMBL:   M29691
- PIR:   F69968
- RefSeq:   NP_390354.1
- ProteinModelPortal:   P40948
- EnsemblBacteria:   EBBACT00000002095
- GeneID:   938517
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU24740
- NMPDR:   fig|224308.1.peg.2478
- GenoList:   BSU24740
- GeneTree:   EBGT00050000001883
- HOGENOM:   HBG338180
- OMA:   HIRHELF
- PhylomeDB:   P40948
- ProtClustDB:   CLSK2301470
- BioCyc:   BSUB:BSU24740-MONOMER
- InterPro:   IPR002523
- PANTHER:   PTHR21535:SF1

Pfam domain/function: PF01544 CorA

EC number: NA

Molecular weight: Translated: 37708; Mature: 37708

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10251238)-; HASH(0x10a016c4)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAHTGKDWFWYQMGPQERSKARDLIHFSHWPQCEKWFENNHHVNFLRVDTTETENEAVF
CCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCCCCCEEE
GSIVYDQGLGEEKDHTVFHFYITRQYFFTINFDFSILREIKGKEVVRQMERADNAIEGFL
EEEEECCCCCCCCCCEEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLGELMNAYLIGVDEFEVKLRKLRWQIKDDNSKSILNRVHLLRHELMIWKNLILSAKKI
HHHHHHHHHHEECCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMALKETFLPQNEGKKDYQRTQLKIDRGFTYISEFEGELNNLLHSEEVITSHRGNEIVKA
HHHHHHHCCCCCCCCHHHHHHHEEHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LTIFTTLFTPITALGALWGMNFSVMPELNWKYGYLFSLLLIVTSTVLIYLYLRKKGWTGD
HHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
MLQERKKKKKPRKRRTL
HHHHHHHHCCCHHHCCH
>Mature Secondary Structure
MKAHTGKDWFWYQMGPQERSKARDLIHFSHWPQCEKWFENNHHVNFLRVDTTETENEAVF
CCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCCCCCEEE
GSIVYDQGLGEEKDHTVFHFYITRQYFFTINFDFSILREIKGKEVVRQMERADNAIEGFL
EEEEECCCCCCCCCCEEEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLGELMNAYLIGVDEFEVKLRKLRWQIKDDNSKSILNRVHLLRHELMIWKNLILSAKKI
HHHHHHHHHHEECCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMALKETFLPQNEGKKDYQRTQLKIDRGFTYISEFEGELNNLLHSEEVITSHRGNEIVKA
HHHHHHHCCCCCCCCHHHHHHHEEHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LTIFTTLFTPITALGALWGMNFSVMPELNWKYGYLFSLLLIVTSTVLIYLYLRKKGWTGD
HHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
MLQERKKKKKPRKRRTL
HHHHHHHHCCCHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 2507524