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The map label for this gene is spoIIAB

Identifier: 16079403

GI number: 16079403

Start: 2444208

End: 2444648

Strand: Reverse

Name: spoIIAB

Synonym: BSU23460

Alternate gene names: 16079403

Gene position: 2444648-2444208 (Counterclockwise)

Preceding gene: 16079404

Following gene: 16079402

Centisome position: 57.99

GC content: 42.18

Gene sequence:

>441_bases
ATGAAAAATGAAATGCACCTTGAGTTTTCTGCCCTCAGTCAGAATGAATCGTTCGCCCGTGTGACAGTTGCTTCATTTAT
AGCTCAGCTGGACCCGACAATGGATGAACTGACTGAAATCAAAACAGTCGTGTCAGAGGCTGTCACGAATGCGATTATCC
ATGGATATGAAGAGAACTGTGAAGGGAAAGTTTACATTTCAGTGACGCTGGAAGATCATGTCGTATATATGACTATTCGT
GATGAAGGCTTAGGCATTACAGATCTTGAAGAAGCCCGTCAGCCTCTATTTACGACTAAGCCTGAGCTTGAGCGCTCTGG
AATGGGCTTTACCATTATGGAAAATTTCATGGATGATGTCAGTATCGATTCATCGCCTGAAATGGGAACAACGATTCGCT
TAACAAAGCACTTATCAAAAAGCAAAGCGCTTTGTAATTAA

Upstream 100 bases:

>100_bases
CTCCTGCGGTGAAGCGATTGTTTGATATGTCGGGTCTGTTTAAAATTATCCGATTTGAACAATCTGAACAGCAGGCACTC
CTGACACTGGGGGTGGCATC

Downstream 100 bases:

>100_bases
GGAGATTTGTTATGGATGTGGAGGTTAAGAAAAACGGCAAAAACGCTCAGCTGAAGGATCATGAAGTAAAGGAATTAATC
AAACAAAGCCAAAATGGCGA

Product: anti-sigma F factor

Products: NA

Alternate protein names: Stage II sporulation protein AB [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MKNEMHLEFSALSQNESFARVTVASFIAQLDPTMDELTEIKTVVSEAVTNAIIHGYEENCEGKVYISVTLEDHVVYMTIR
DEGLGITDLEEARQPLFTTKPELERSGMGFTIMENFMDDVSIDSSPEMGTTIRLTKHLSKSKALCN

Sequences:

>Translated_146_residues
MKNEMHLEFSALSQNESFARVTVASFIAQLDPTMDELTEIKTVVSEAVTNAIIHGYEENCEGKVYISVTLEDHVVYMTIR
DEGLGITDLEEARQPLFTTKPELERSGMGFTIMENFMDDVSIDSSPEMGTTIRLTKHLSKSKALCN
>Mature_146_residues
MKNEMHLEFSALSQNESFARVTVASFIAQLDPTMDELTEIKTVVSEAVTNAIIHGYEENCEGKVYISVTLEDHVVYMTIR
DEGLGITDLEEARQPLFTTKPELERSGMGFTIMENFMDDVSIDSSPEMGTTIRLTKHLSKSKALCN

Specific function: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases si

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010194
- InterPro:   IPR003594 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 16356; Mature: 16356

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEMHLEFSALSQNESFARVTVASFIAQLDPTMDELTEIKTVVSEAVTNAIIHGYEENC
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGKVYISVTLEDHVVYMTIRDEGLGITDLEEARQPLFTTKPELERSGMGFTIMENFMDDV
CCEEEEEEEEECEEEEEEECCCCCCCCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHC
SIDSSPEMGTTIRLTKHLSKSKALCN
CCCCCCCCCCEEHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNEMHLEFSALSQNESFARVTVASFIAQLDPTMDELTEIKTVVSEAVTNAIIHGYEENC
CCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGKVYISVTLEDHVVYMTIRDEGLGITDLEEARQPLFTTKPELERSGMGFTIMENFMDDV
CCEEEEEEEEECEEEEEEECCCCCCCCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHC
SIDSSPEMGTTIRLTKHLSKSKALCN
CCCCCCCCCCEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA