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The map label for this gene is asnC

Identifier: 16079293

GI number: 16079293

Start: 2346224

End: 2347516

Strand: Reverse

Name: asnC

Synonym: BSU22360

Alternate gene names: 16079293

Gene position: 2347516-2346224 (Counterclockwise)

Preceding gene: 16079294

Following gene: 16079292

Centisome position: 55.69

GC content: 44.16

Gene sequence:

>1293_bases
TTGAAAACAACAATCAACCAAGTGTACAAGCACGTAGGTGAGGAAGTAACGATCGGAGCTTGGGTCGCTAATAAGCGTTC
AAGCGGGAAAATTGCGTTTTTACAGCTTCGGGACGGTACCGGTTTTATTCAGGGTGTCGTAGTAAAAGCGGAAGTGGAAG
AAAGCATTTTCCAAACAGCTAAATCAGTGACGCAGGAAACGTCGCTCTATATAAAAGGGATTGTCAAAGAGGACGAGCGT
TCTCCGCTTGGATATGAACTTGCTGTGACAGATATTGAAGTCATTCACGAAGCGACCGATTATCCAATTACACCAAAAGA
ACACGGAACGGAATTTTTGATGGATCACAGACATTTATGGCTGCGTTCAAAGCGCCAGCATGCGATCATGAAAATCCGTA
ATGAAATCATTCGCGCGACTTACGAATTCTTTAATAACGAAGGCTTCGTAAAAGTGGATCCGCCGATTTTGACTGGAAGC
GCACCTGAAGGAACAACAGAACTCTTTGCGACAAAGTACTTTGATGAAGATGCATATCTGTCTCAAAGCGGACAGCTCTA
CATGGAAGCTGCGGCAATGGCTTTAGGAAAAGTATTCTCTTTCGGACCGACATTCAGAGCGGAAAAGTCTAAAACAAAGC
GTCACTTAATCGAATTCTGGATGATCGAACCGGAAATGGCGTTTGTAGAATTTGAAGAAAACCTTCAAGTACAGGAAAAT
TACGTTTCTTTCATCGTGCAATCAGTTCTTAAAAATTGCAAAATTGAACTAAACACATTGGGAAGAGACACGTCAAAACT
TGAGCAAATCAAAGCCCCGTTCCCAAGAATTACGTATGATGAAGCGATTGAATTTCTGAAAGAAAAAGGCTTTGACGATA
TCGAGTGGGGAGATGATTTCGGAGCGCCTCATGAAACAGCGATTGCTGAACATTATGACAAACCGGTATTCATCACTCGC
TATCCGACGTCCTTAAAACCGTTCTATATGCAGCCGGCTTCTGACCGTGAGGACGTTGTGCTTTGCGCTGACTTGATTGC
GCCGGAAGGCTATGGAGAAATCATCGGCGGGTCTGAACGGATTCACGATATGGAACTTTTGGAATCGCGTCTTAAAGAAC
ATGGACTGGATTCTGACGCTTATAAATGGTATGCTGAACTTAGAAAATATGGATCAGTTCCTCATTCCGGCTTCGGCCTT
GGATTAGAGCGGACAGTAGCTTGGATCAGCGGAGCGCCTCACGTTCGTGAAACGATTCCGTTCCCAAGACTGTTAAACCG
TCTGTATCCGTAA

Upstream 100 bases:

>100_bases
TTGACCCGGTTAGTTAAGAGCGGGTATAATAAAGTGATGATAAAAGAGTTCGCGGGGCAATGAGCTTCCGAATGTCTTTC
TTGTTTTGGAGGGAAATATG

Downstream 100 bases:

>100_bases
TACATTCAAATGAAACAAAAAAGAGTCTCCTGCAAGGGAGACTTTTTACAGTAAAGGGGCAATCACAATCCTTTACAGTA
AGAGGTGTGACGATGAAAAA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKTTINQVYKHVGEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTAKSVTQETSLYIKGIVKEDER
SPLGYELAVTDIEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNNEGFVKVDPPILTGS
APEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLQVQEN
YVSFIVQSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDFGAPHETAIAEHYDKPVFITR
YPTSLKPFYMQPASDREDVVLCADLIAPEGYGEIIGGSERIHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGL
GLERTVAWISGAPHVRETIPFPRLLNRLYP

Sequences:

>Translated_430_residues
MKTTINQVYKHVGEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTAKSVTQETSLYIKGIVKEDER
SPLGYELAVTDIEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNNEGFVKVDPPILTGS
APEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLQVQEN
YVSFIVQSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDFGAPHETAIAEHYDKPVFITR
YPTSLKPFYMQPASDREDVVLCADLIAPEGYGEIIGGSERIHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGL
GLERTVAWISGAPHVRETIPFPRLLNRLYP
>Mature_430_residues
MKTTINQVYKHVGEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTAKSVTQETSLYIKGIVKEDER
SPLGYELAVTDIEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHAIMKIRNEIIRATYEFFNNEGFVKVDPPILTGS
APEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLQVQEN
YVSFIVQSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDFGAPHETAIAEHYDKPVFITR
YPTSLKPFYMQPASDREDVVLCADLIAPEGYGEIIGGSERIHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGL
GLERTVAWISGAPHVRETIPFPRLLNRLYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=438, Percent_Identity=35.3881278538813, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI4758762, Length=437, Percent_Identity=33.8672768878719, Blast_Score=248, Evalue=5e-66,
Organism=Homo sapiens, GI45439306, Length=458, Percent_Identity=30.7860262008734, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI40789249, Length=233, Percent_Identity=27.4678111587983, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787161, Length=450, Percent_Identity=35.5555555555556, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1789256, Length=466, Percent_Identity=24.2489270386266, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1790571, Length=468, Percent_Identity=23.9316239316239, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788173, Length=243, Percent_Identity=25.5144032921811, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71984122, Length=440, Percent_Identity=35.4545454545455, Blast_Score=267, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI17556372, Length=410, Percent_Identity=32.6829268292683, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17551876, Length=456, Percent_Identity=28.5087719298246, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI71994340, Length=464, Percent_Identity=22.8448275862069, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17535925, Length=464, Percent_Identity=22.8448275862069, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17535927, Length=464, Percent_Identity=22.8448275862069, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321807, Length=443, Percent_Identity=36.7945823927765, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6319872, Length=468, Percent_Identity=32.2649572649573, Blast_Score=223, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6323011, Length=468, Percent_Identity=31.6239316239316, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6325153, Length=244, Percent_Identity=26.2295081967213, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19921528, Length=433, Percent_Identity=35.5658198614319, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI19922416, Length=443, Percent_Identity=31.3769751693002, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI17136276, Length=461, Percent_Identity=28.4164859002169, Blast_Score=167, Evalue=9e-42,
Organism=Drosophila melanogaster, GI24640851, Length=474, Percent_Identity=21.5189873417722, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24640849, Length=477, Percent_Identity=21.8029350104822, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 49084; Mature: 49084

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTINQVYKHVGEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTA
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEEHHHHHHHHHHH
KSVTQETSLYIKGIVKEDERSPLGYELAVTDIEVIHEATDYPITPKEHGTEFLMDHRHLW
HHHHHHHHHHEEEEECCCCCCCCCEEEEEHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
LRSKRQHAIMKIRNEIIRATYEFFNNEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHHHHCCCCHHH
SQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLQVQEN
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCEEEEEECCCCHHHHH
YVSFIVQSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDF
HHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
GAPHETAIAEHYDKPVFITRYPTSLKPFYMQPASDREDVVLCADLIAPEGYGEIIGGSER
CCCCHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCCCEEEEHHHHCCCCCCCCCCCCHH
IHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGLGLERTVAWISGAPHVRETIP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHCCC
FPRLLNRLYP
HHHHHHHHCC
>Mature Secondary Structure
MKTTINQVYKHVGEEVTIGAWVANKRSSGKIAFLQLRDGTGFIQGVVVKAEVEESIFQTA
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEEHHHHHHHHHHH
KSVTQETSLYIKGIVKEDERSPLGYELAVTDIEVIHEATDYPITPKEHGTEFLMDHRHLW
HHHHHHHHHHEEEEECCCCCCCCCEEEEEHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
LRSKRQHAIMKIRNEIIRATYEFFNNEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCCCCHHHHHHHHCCCCHHH
SQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFEENLQVQEN
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCEEEEEECCCCHHHHH
YVSFIVQSVLKNCKIELNTLGRDTSKLEQIKAPFPRITYDEAIEFLKEKGFDDIEWGDDF
HHHHHHHHHHHHCEEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
GAPHETAIAEHYDKPVFITRYPTSLKPFYMQPASDREDVVLCADLIAPEGYGEIIGGSER
CCCCHHHHHHHCCCCEEEEECCCCCCCEEECCCCCCCCEEEEHHHHCCCCCCCCCCCCHH
IHDMELLESRLKEHGLDSDAYKWYAELRKYGSVPHSGFGLGLERTVAWISGAPHVRETIP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCHHHCCC
FPRLLNRLYP
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA