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The map label for this gene is ggt

Identifier: 16078902

GI number: 16078902

Start: 2004677

End: 2006440

Strand: Direct

Name: ggt

Synonym: BSU18410

Alternate gene names: 16078902

Gene position: 2004677-2006440 (Clockwise)

Preceding gene: 255767431

Following gene: 16078904

Centisome position: 47.55

GC content: 43.88

Gene sequence:

>1764_bases
ATGAAAAGAACGTGGAACGTCTGTTTAACAGCTCTGCTTAGTGTTCTGTTAGTCGCTGGAAGTGTCCCTTTTCACGCGGA
AGCTAAAAAACCGCCCAAAAGCTACGATGAGTACAAACAAGTAGATGTTGGAAAAGACGGCATGGTTGCGACCGCACATC
CTCTTGCTTCTGAAATCGGTGCTGATGTGCTGAAAAAAGGAGGAAATGCTATTGACGCAGCGGTTGCCATTCAATTTGCA
CTCAATGTAACAGAGCCGATGATGTCAGGTATTGGCGGCGGCGGTTTTATGATGGTGTATGACGGAAAAACGAAGGATAC
AACGATAATCGACAGCCGTGAGCGTGCTCCAGCAGGCGCAACTCCTGATATGTTTCTGGACGAAAACGGCAAAGCAATTC
CTTTCTCTGAACGTGTAACAAAAGGTACTGCCGTTGGTGTTCCAGGCACTCTGAAAGGGCTGGAAGAAGCCTTGGATAAA
TGGGGAACCCGTTCGATGAAGCAATTAATTACCCCTTCTATTAAACTCGCTGAAAAAGGCTTTCCGATTGATTCGGTGTT
GGCAGAGGCCATTTCTGATTATCAGGAAAAGCTTTCACGGACTGCCGCAAAAGATGTATTTTTACCAAATGGCGAACCGC
TTAAAGAAGGAGATACCCTTATTCAAAAGGATTTGGCTAAAACATTTAAGCTTATTCGCTCCAAAGGCACTGACGCTTTT
TATAAAGGAAAATTCGCCAAGACGCTTTCTGACACTGTCCAGGATTTCGGCGGATCAATGACAGAAAAAGATTTAGAAAA
TTACGACATTACAATTGATGAACCGATTTGGGGAGATTATCAAGGCTATCAAATCGCTACTACTCCTCCTCCAAGCTCCG
GCGGTATTTTCTTATTGCAAATGCTGAAAATCCTTGATCATTTTAACCTTTCACAATACGATGTCCGCTCATGGGAAAAA
TATCAGCTGCTTGCTGAAACGATGCATTTGTCATATGCCGACCGTGCGTCTTACGCAGGTGATCCCGAATTTGTAAATGT
TCCTCTCAAAGGCCTGCTTCACCCCGATTATATTAAAGAACGCCAGCAATTAATCAACCTAGATCAAGTGAATAAAAAAC
CGAAAGCCGGTGACCCTTGGAAATACCAAGAAGGATCAGCAAACTATAAACAAGTTGAACAGCCGAAAGACAAAGTAGAA
GGCCAAACAACCCACTTTACAGTTGCTGACCGTTGGGGAAATGTTGTTTCTTATACAACAACAATCGAACAGCTATTCGG
AACGGGTATTATGGTCCCTGATTACGGTGTTATTTTAAACAATGAATTAACGGATTTTGATGCGATACCAGGCGGAGCTA
ACGAAGTACAGCCAAACAAACGGCCTTTAAGCAGCATGACCCCGACGATTTTATTTAAGGATGACAAGCCTGTCCTCACG
GTTGGATCTCCTGGCGGGGCCACAATTATTTCATCCGTTTTGCAAACCATTCTCTACCACATTGAATATGGTATGGAATT
AAAAGCAGCTGTTGAAGAGCCGAGAATTTACACAAACAGCATGAGCTCTTACCGTTACGAAGACGGAGTTCCTAAAGATG
TCCTCAGCAAGCTAAACGGCATGGGCCACAAATTCGGCACAAGTCCGGTGGATATCGGAAACGTGCAAAGTATATCGATC
GACCATGAAAACGGCACCTTTAAAGGTGTAGCTGATTCAAGCAGAAACGGCGCGGCGATCGGCATTAATTTAAAACGTAA
ATAA

Upstream 100 bases:

>100_bases
GCATTATGCACTATATAATATACCATTTGTCACTTGTGAAAACGCTGTAATTTTTTTACGCTAAGATTGTAACAATACAG
CTTCATATAGGAGGGAGAAC

Downstream 100 bases:

>100_bases
ATAAAAAACTGTACTCGCTTCAAATGAGTACAGTTTTTTCATGCAGATCTTTAAAATAAAAACTGACAAACGTCTTTATT
CTGCTAATGCACGTCTATCT

Product: membrane bound gamma-glutamyltranspeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGKDGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFA
LNVTEPMMSGIGGGGFMMVYDGKTKDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDK
WGTRSMKQLITPSIKLAEKGFPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQKDLAKTFKLIRSKGTDAF
YKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQGYQIATTPPPSSGGIFLLQMLKILDHFNLSQYDVRSWEK
YQLLAETMHLSYADRASYAGDPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKVE
GQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQPNKRPLSSMTPTILFKDDKPVLT
VGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIYTNSMSSYRYEDGVPKDVLSKLNGMGHKFGTSPVDIGNVQSISI
DHENGTFKGVADSSRNGAAIGINLKRK

Sequences:

>Translated_587_residues
MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGKDGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFA
LNVTEPMMSGIGGGGFMMVYDGKTKDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDK
WGTRSMKQLITPSIKLAEKGFPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQKDLAKTFKLIRSKGTDAF
YKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQGYQIATTPPPSSGGIFLLQMLKILDHFNLSQYDVRSWEK
YQLLAETMHLSYADRASYAGDPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKVE
GQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQPNKRPLSSMTPTILFKDDKPVLT
VGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIYTNSMSSYRYEDGVPKDVLSKLNGMGHKFGTSPVDIGNVQSISI
DHENGTFKGVADSSRNGAAIGINLKRK
>Mature_587_residues
MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGKDGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFA
LNVTEPMMSGIGGGGFMMVYDGKTKDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDK
WGTRSMKQLITPSIKLAEKGFPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQKDLAKTFKLIRSKGTDAF
YKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQGYQIATTPPPSSGGIFLLQMLKILDHFNLSQYDVRSWEK
YQLLAETMHLSYADRASYAGDPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKVE
GQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQPNKRPLSSMTPTILFKDDKPVLT
VGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIYTNSMSSYRYEDGVPKDVLSKLNGMGHKFGTSPVDIGNVQSISI
DHENGTFKGVADSSRNGAAIGINLKRK

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=546, Percent_Identity=30.952380952381, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI73915090, Length=546, Percent_Identity=30.952380952381, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI73915096, Length=546, Percent_Identity=30.952380952381, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI73915094, Length=546, Percent_Identity=30.952380952381, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI113429326, Length=549, Percent_Identity=30.4189435336976, Blast_Score=217, Evalue=3e-56,
Organism=Homo sapiens, GI113429324, Length=544, Percent_Identity=30.3308823529412, Blast_Score=213, Evalue=6e-55,
Organism=Homo sapiens, GI153266885, Length=562, Percent_Identity=27.9359430604982, Blast_Score=199, Evalue=5e-51,
Organism=Homo sapiens, GI153266901, Length=563, Percent_Identity=27.886323268206, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI109148539, Length=502, Percent_Identity=29.4820717131474, Blast_Score=172, Evalue=9e-43,
Organism=Homo sapiens, GI153266907, Length=563, Percent_Identity=26.2877442273535, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI30581157, Length=193, Percent_Identity=33.160621761658, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI30581155, Length=193, Percent_Identity=33.160621761658, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI218505805, Length=193, Percent_Identity=30.5699481865285, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI310124095, Length=192, Percent_Identity=30.7291666666667, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1789856, Length=543, Percent_Identity=41.2523020257827, Blast_Score=393, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17506189, Length=585, Percent_Identity=29.7435897435897, Blast_Score=219, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI193208245, Length=497, Percent_Identity=31.9919517102616, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI193208247, Length=497, Percent_Identity=31.9919517102616, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI72000294, Length=493, Percent_Identity=32.8600405679513, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI212646519, Length=493, Percent_Identity=33.0628803245436, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17542894, Length=496, Percent_Identity=31.0483870967742, Blast_Score=198, Evalue=7e-51,
Organism=Caenorhabditis elegans, GI17564448, Length=437, Percent_Identity=27.2311212814645, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI72001497, Length=230, Percent_Identity=28.695652173913, Blast_Score=99, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI72001495, Length=230, Percent_Identity=28.695652173913, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323330, Length=585, Percent_Identity=29.9145299145299, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI161077878, Length=561, Percent_Identity=30.4812834224599, Blast_Score=214, Evalue=2e-55,
Organism=Drosophila melanogaster, GI161077880, Length=561, Percent_Identity=30.4812834224599, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI45551474, Length=561, Percent_Identity=30.4812834224599, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24642670, Length=562, Percent_Identity=30.4270462633452, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24642666, Length=562, Percent_Identity=30.4270462633452, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI161077496, Length=518, Percent_Identity=28.7644787644788, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI18859893, Length=524, Percent_Identity=30.5343511450382, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI18859741, Length=514, Percent_Identity=26.2645914396887, Blast_Score=136, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 64190; Mature: 64190

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGKDGMVATAHPLASEIG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCHHHHHHH
ADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKTKDTTIIDSRERAPAGA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCCCCCCC
TPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDKWGTRSMKQLITPSIKLAEKG
CCCCEECCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHCC
FPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQKDLAKTFKLIRSKGTDAF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
YKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQGYQIATTPPPSSGGIFLLQ
HCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCCCEEEEECCCCCCCCHHHHH
MLKILDHFNLSQYDVRSWEKYQLLAETMHLSYADRASYAGDPEFVNVPLKGLLHPDYIKE
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCHHHHHH
RQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKVEGQTTHFTVADRWGNVVSYTT
HHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCCCEEEEECCCCCCEEEHHH
TIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQPNKRPLSSMTPTILFKDDKPVLT
HHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEE
VGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIYTNSMSSYRYEDGVPKDVLSKLNG
ECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHC
MGHKFGTSPVDIGNVQSISIDHENGTFKGVADSSRNGAAIGINLKRK
CCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGKDGMVATAHPLASEIG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEECCHHHHHHH
ADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKTKDTTIIDSRERAPAGA
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCCCCCCC
TPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDKWGTRSMKQLITPSIKLAEKG
CCCCEECCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHCC
FPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQKDLAKTFKLIRSKGTDAF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
YKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQGYQIATTPPPSSGGIFLLQ
HCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCCCCCCCCEEEEECCCCCCCCHHHHH
MLKILDHFNLSQYDVRSWEKYQLLAETMHLSYADRASYAGDPEFVNVPLKGLLHPDYIKE
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHCCCHHHHHH
RQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKVEGQTTHFTVADRWGNVVSYTT
HHHHCCHHHHCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCCCCEEEEECCCCCCEEEHHH
TIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQPNKRPLSSMTPTILFKDDKPVLT
HHHHHHCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEE
VGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIYTNSMSSYRYEDGVPKDVLSKLNG
ECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCEEECCCCCCCCCCCCCHHHHHHHHC
MGHKFGTSPVDIGNVQSISIDHENGTFKGVADSSRNGAAIGINLKRK
CCCCCCCCCCCCCCEEEEEEECCCCCEECCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA