Click here to switch to the map view.

The map label for this gene is yogA

Identifier: 16078904

GI number: 16078904

Start: 2007526

End: 2008515

Strand: Direct

Name: yogA

Synonym: BSU18430

Alternate gene names: 16078904

Gene position: 2007526-2008515 (Clockwise)

Preceding gene: 16078902

Following gene: 255767435

Centisome position: 47.62

GC content: 44.04

Gene sequence:

>990_bases
ATGAAAGCTGTAATTCACAACGGAAAAGCCGGTCTTCTGGGGTTATCAGTTCAGGACGTTCCATCAACAAAGCCTGGATA
CGGAGAGGTAAAGGTTAAATTAAAATCTGCAGGCCTGAATCATCGTGACTTGTTTCTTATGAAAAACAAATCTGAACAAG
ATCCTCACATGATACTGGGTTCTGACGGCGCGGGTATCATCGAAGAGATTGGTGAAGGCGTGAAAAATGTTACTGTTCAG
ACAGAAGTAGTCATTTTCCCGACATTGAACTGGGATTTGACAGAAAATGTTCCACCTGTACCTGAGATTCTGGGAGGTCC
TTCGGACGGAACACTTGCTGAATATGTGATCATTCCTTCACAAAATGCAATCAAAAAACCTGCTTATTTATCTTGGGAAG
AAGCGGGCGTTTTACCTTTATCCGCTTTAACTGCATATCGGGCTCTGTTTACAAAGGGGCAATTAAAAAAAGGCGAGCAT
CTATTGATACCCGGCATCGGCAGCGGTGTAGCAACCTACGCTTTATTTATGGCTAAGGCGATTGGGGCAACAGTAAGCGT
GACCTCCCGCAGTGAGGAGAAAAGAAAAAAGGCGCTGAAATTAGGTGCTGATTACGCATTTGACAGCTACAGCAATTGGG
ATGAGCAGTTGCAGGGAAAAAAGATAGATGTTGTTCTTGACAGCATAGGACCTGCCCTCTTTTCGGAATACTTCCGCCAT
GTAAAACCAAATGGCCGTATTGTCAGCTTTGGGGCAAGCTCAGGGGATAATCTCAGTTTTCCGGTGCGTTCTTTATTCTT
TCCTCAGGTCAATGTTTTGGGAACCTCGATGGGAAGCGGTGAGGAATTTCAAGCTATGCTCGCTTTCATTGACAAACATA
AGCTGCGGCCTGTAATTGACCGGATATATCCTTTAGAAAAAGCATGTGAAGCATATAAAAGAATGCAGGAAGGCAGACAG
TTTGGAAACATCGGGATCGTAATGGAATAA

Upstream 100 bases:

>100_bases
AAGTGATATTGGCTATCATATTTGTTCATTTTACTCGAAGAAAACCGCTATGTAAAATATGTAAAGATATGAAAATACAA
TTAATGAGGAGGCAGACAGC

Downstream 100 bases:

>100_bases
AAAAAGAAACCGGCTGGCAGCCAGACCGGTTTCTCTTATATGATAATCCCCTTTATTTACGGAAGAACTGAACTCCCCAT
CAAATATCGATCCACTTCAC

Product: oxidoreductase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKAVIHNGKAGLLGLSVQDVPSTKPGYGEVKVKLKSAGLNHRDLFLMKNKSEQDPHMILGSDGAGIIEEIGEGVKNVTVQ
TEVVIFPTLNWDLTENVPPVPEILGGPSDGTLAEYVIIPSQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEH
LLIPGIGSGVATYALFMAKAIGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKIDVVLDSIGPALFSEYFRH
VKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGEEFQAMLAFIDKHKLRPVIDRIYPLEKACEAYKRMQEGRQ
FGNIGIVME

Sequences:

>Translated_329_residues
MKAVIHNGKAGLLGLSVQDVPSTKPGYGEVKVKLKSAGLNHRDLFLMKNKSEQDPHMILGSDGAGIIEEIGEGVKNVTVQ
TEVVIFPTLNWDLTENVPPVPEILGGPSDGTLAEYVIIPSQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEH
LLIPGIGSGVATYALFMAKAIGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKIDVVLDSIGPALFSEYFRH
VKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGEEFQAMLAFIDKHKLRPVIDRIYPLEKACEAYKRMQEGRQ
FGNIGIVME
>Mature_329_residues
MKAVIHNGKAGLLGLSVQDVPSTKPGYGEVKVKLKSAGLNHRDLFLMKNKSEQDPHMILGSDGAGIIEEIGEGVKNVTVQ
TEVVIFPTLNWDLTENVPPVPEILGGPSDGTLAEYVIIPSQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEH
LLIPGIGSGVATYALFMAKAIGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKIDVVLDSIGPALFSEYFRH
VKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGEEFQAMLAFIDKHKLRPVIDRIYPLEKACEAYKRMQEGRQ
FGNIGIVME

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily

Homologues:

Organism=Homo sapiens, GI22538446, Length=348, Percent_Identity=28.448275862069, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI22538444, Length=348, Percent_Identity=28.448275862069, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI18379349, Length=330, Percent_Identity=25.7575757575758, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI24308257, Length=359, Percent_Identity=24.2339832869081, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI194239674, Length=313, Percent_Identity=25.5591054313099, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI13236495, Length=313, Percent_Identity=25.5591054313099, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI47519420, Length=337, Percent_Identity=28.7833827893175, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI194239676, Length=308, Percent_Identity=25, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790485, Length=239, Percent_Identity=30.9623430962343, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787863, Length=260, Percent_Identity=26.5384615384615, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081918, Length=316, Percent_Identity=23.1012658227848, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562878, Length=334, Percent_Identity=25.748502994012, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17507255, Length=322, Percent_Identity=25.4658385093168, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=315, Percent_Identity=23.8095238095238, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=333, Percent_Identity=25.5255255255255, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=325, Percent_Identity=24, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323961, Length=341, Percent_Identity=23.7536656891496, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=328, Percent_Identity=22.2560975609756, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=328, Percent_Identity=22.5609756097561, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=328, Percent_Identity=24.390243902439, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24581345, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920632, Length=234, Percent_Identity=27.3504273504274, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI221330659, Length=234, Percent_Identity=27.3504273504274, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YOGA_BACSU (O35017)

Other databases:

- EMBL:   AL009126
- PIR:   F69905
- RefSeq:   NP_389725.1
- ProteinModelPortal:   O35017
- SMR:   O35017
- EnsemblBacteria:   EBBACT00000001806
- GeneID:   940019
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU18430
- NMPDR:   fig|224308.1.peg.1847
- GenoList:   BSU18430
- GeneTree:   EBGT00070000031803
- HOGENOM:   HBG753318
- OMA:   HRDLFLM
- ProtClustDB:   CLSK887373
- BioCyc:   BSUB:BSU18430-MONOMER
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR11695

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N; SSF50129 GroES_like

EC number: 1.1.1.1

Molecular weight: Translated: 35812; Mature: 35812

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVIHNGKAGLLGLSVQDVPSTKPGYGEVKVKLKSAGLNHRDLFLMKNKSEQDPHMILG
CCCEEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCEEEE
SDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPEILGGPSDGTLAEYVIIPS
CCCCHHHHHHCCHHHCEEEEEEEEEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEEEECC
QNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEHLLIPGIGSGVATYALFMAKA
CCCCCCCCEECHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHH
IGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKIDVVLDSIGPALFSEYFRH
HCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEEEEEEHHCCHHHHHHHHHH
VKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGEEFQAMLAFIDKHKLRPVID
CCCCCEEEEECCCCCCCCCCCHHHHHCCCHHEEECCCCCCHHHHHHHHHHHHHCCHHHHH
RIYPLEKACEAYKRMQEGRQFGNIGIVME
HHCCHHHHHHHHHHHHHCHHCCCEEEEEC
>Mature Secondary Structure
MKAVIHNGKAGLLGLSVQDVPSTKPGYGEVKVKLKSAGLNHRDLFLMKNKSEQDPHMILG
CCCEEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCEEEE
SDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPEILGGPSDGTLAEYVIIPS
CCCCHHHHHHCCHHHCEEEEEEEEEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEEEECC
QNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEHLLIPGIGSGVATYALFMAKA
CCCCCCCCEECHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHH
IGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKIDVVLDSIGPALFSEYFRH
HCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCEEEEEEHHCCHHHHHHHHHH
VKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGEEFQAMLAFIDKHKLRPVID
CCCCCEEEEECCCCCCCCCCCHHHHHCCCHHEEECCCCCCHHHHHHHHHHHHHCCHHHHH
RIYPLEKACEAYKRMQEGRQFGNIGIVME
HHCCHHHHHHHHHHHHHCHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377