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The map label for this gene is xylB

Identifier: 16078824

GI number: 16078824

Start: 1893396

End: 1894895

Strand: Direct

Name: xylB

Synonym: BSU17610

Alternate gene names: 16078824

Gene position: 1893396-1894895 (Clockwise)

Preceding gene: 255767417

Following gene: 255767418

Centisome position: 44.91

GC content: 41.4

Gene sequence:

>1500_bases
ATGAAGTATGTCATTGGAATAGATCTTGGAACGAGTGCTGTTAAAACCATTTTAGTTAACCAAAACGGCAAGGTTTGTGC
AGAAACGTCCAAAAGGTATCCGCTCATCCAAGAGAAGGCGGGATATAGTGAGCAAAATCCTGAAGACTGGGTTCAGCAAA
CAATTGAAGCATTGGCTGAATTGGTTTCTATATCCAATGTTCAAGCCAAGGATATTGACGGGATAAGCTATTCGGGACAA
ATGCATGGATTAGTACTGCTTGACCAAGATCGTCAGGTGTTACGTAATGCAATTCTTTGGAATGATACCAGAACAACGCC
TCAATGTATAAGGATGACCGAGAAATTTGGCGATCATCTTCTTGACATCACAAAAAACCGTGTTTTAGAAGGGTTTACAT
TACCTAAAATGTTATGGGTAAAGGAACATGAACCTGAACTTTTTAAAAAAACTGCTGTGTTTTTGCTTCCGAAAGACTAC
GTGCGATTCCGTATGACCGGTGTCATTCACACCGAATACTCCGATGCAGCAGGAACTTTACTTTTACATATTACTCGCAA
GGAGTGGAGCAATGATATTTGCAATCAAATTGGTATTTCTGCAGATATTTGTCCTCCGCTTGTTGAATCTCATGATTGTG
TAGGATCGCTGCTTCCGCACGTTGCCGCGAAGACCGGGCTATTAGAAAAAACAAAAGTGTACGCTGGGGGAGCAGATAAT
GCTTGCGGCGCTATTGGAGCAGGTATCCTTTCTTCCGGAAAAACATTATGCAGTATTGGGACGTCAGGGGTCATACTTTC
CTACGAAGAAGAAAAAGAAAGAGACTTTAAAGGGAAAGTCCACTTTTTTAATCATGGAAAAAAGGATTCTTTTTATACGA
TGGGCGTCACGCTCGCTGCAGGATACAGCTTGGACTGGTTTAAAAGAACGTTTGCACCAAACGAATCGTTTGAGCAATTA
TTGCAGGGGGTGGAAGCTATTCCGATAGGAGCCAATGGACTGCTATACACTCCTTATTTGGTTGGTGAAAGAACGCCGCA
TGCTGATTCTTCTATTCGGGGAAGCTTGATCGGAATGGATGGAGCCCATAATAGAAAGCATTTTTTGAGGGCAATAATGG
AAGGTATCACATTCTCTTTACATGAATCAATTGAGCTATTCCGCGAAGCGGGAAAATCAGTTCATACTGTTGTTTCTATT
GGTGGGGGAGCTAAAAATGATACGTGGCTGCAAATGCAAGCTGATATTTTCAATACGAGGGTAATTAAGTTAGAAAATGA
ACAAGGGCCAGCTATGGGGGCTGCAATGCTGGCTGCCTTTGGAAGCGGTTGGTTTGAATCACTTGAAGAATGTGCAGAGC
AGTTCATTCGTGAGGCTGCTGCATTTTATCCAAAGGCGCAAAATGTTCAAAAATATAAAACACTATTTGATTTGTATAAG
AACATTTACACTCACACAAAGGATCTCAATACAGCTTTGAAGAGCTTTCGAAAAAACTAA

Upstream 100 bases:

>100_bases
TCATGATTCCTTTCCTATTGCTTGTTGTTATGACGGGTAACTTCTATAATTAGGATTTATTTAGAGTGAATGGTTTTTTA
AAAGGGCAAGGAGTGAAAAA

Downstream 100 bases:

>100_bases
TGATGTTATTGTCTGGAGATCAACCGAAGAACAATTAATGATCAATCATCATCAAAGGCCTTTGATAACATGGCTGCCTT
CTTTTGAAAAGATGGTGAGA

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MKYVIGIDLGTSAVKTILVNQNGKVCAETSKRYPLIQEKAGYSEQNPEDWVQQTIEALAELVSISNVQAKDIDGISYSGQ
MHGLVLLDQDRQVLRNAILWNDTRTTPQCIRMTEKFGDHLLDITKNRVLEGFTLPKMLWVKEHEPELFKKTAVFLLPKDY
VRFRMTGVIHTEYSDAAGTLLLHITRKEWSNDICNQIGISADICPPLVESHDCVGSLLPHVAAKTGLLEKTKVYAGGADN
ACGAIGAGILSSGKTLCSIGTSGVILSYEEEKERDFKGKVHFFNHGKKDSFYTMGVTLAAGYSLDWFKRTFAPNESFEQL
LQGVEAIPIGANGLLYTPYLVGERTPHADSSIRGSLIGMDGAHNRKHFLRAIMEGITFSLHESIELFREAGKSVHTVVSI
GGGAKNDTWLQMQADIFNTRVIKLENEQGPAMGAAMLAAFGSGWFESLEECAEQFIREAAAFYPKAQNVQKYKTLFDLYK
NIYTHTKDLNTALKSFRKN

Sequences:

>Translated_499_residues
MKYVIGIDLGTSAVKTILVNQNGKVCAETSKRYPLIQEKAGYSEQNPEDWVQQTIEALAELVSISNVQAKDIDGISYSGQ
MHGLVLLDQDRQVLRNAILWNDTRTTPQCIRMTEKFGDHLLDITKNRVLEGFTLPKMLWVKEHEPELFKKTAVFLLPKDY
VRFRMTGVIHTEYSDAAGTLLLHITRKEWSNDICNQIGISADICPPLVESHDCVGSLLPHVAAKTGLLEKTKVYAGGADN
ACGAIGAGILSSGKTLCSIGTSGVILSYEEEKERDFKGKVHFFNHGKKDSFYTMGVTLAAGYSLDWFKRTFAPNESFEQL
LQGVEAIPIGANGLLYTPYLVGERTPHADSSIRGSLIGMDGAHNRKHFLRAIMEGITFSLHESIELFREAGKSVHTVVSI
GGGAKNDTWLQMQADIFNTRVIKLENEQGPAMGAAMLAAFGSGWFESLEECAEQFIREAAAFYPKAQNVQKYKTLFDLYK
NIYTHTKDLNTALKSFRKN
>Mature_499_residues
MKYVIGIDLGTSAVKTILVNQNGKVCAETSKRYPLIQEKAGYSEQNPEDWVQQTIEALAELVSISNVQAKDIDGISYSGQ
MHGLVLLDQDRQVLRNAILWNDTRTTPQCIRMTEKFGDHLLDITKNRVLEGFTLPKMLWVKEHEPELFKKTAVFLLPKDY
VRFRMTGVIHTEYSDAAGTLLLHITRKEWSNDICNQIGISADICPPLVESHDCVGSLLPHVAAKTGLLEKTKVYAGGADN
ACGAIGAGILSSGKTLCSIGTSGVILSYEEEKERDFKGKVHFFNHGKKDSFYTMGVTLAAGYSLDWFKRTFAPNESFEQL
LQGVEAIPIGANGLLYTPYLVGERTPHADSSIRGSLIGMDGAHNRKHFLRAIMEGITFSLHESIELFREAGKSVHTVVSI
GGGAKNDTWLQMQADIFNTRVIKLENEQGPAMGAAMLAAFGSGWFESLEECAEQFIREAAAFYPKAQNVQKYKTLFDLYK
NIYTHTKDLNTALKSFRKN

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family

Homologues:

Organism=Homo sapiens, GI164663828, Length=554, Percent_Identity=23.4657039711191, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI41393575, Length=421, Percent_Identity=23.7529691211401, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI42794763, Length=455, Percent_Identity=22.6373626373626, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4504007, Length=455, Percent_Identity=22.6373626373626, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI189409120, Length=455, Percent_Identity=22.6373626373626, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI18860918, Length=487, Percent_Identity=21.9712525667351, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1789987, Length=480, Percent_Identity=36.25, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1790005, Length=501, Percent_Identity=27.5449101796407, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1790361, Length=489, Percent_Identity=22.6993865030675, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1789168, Length=484, Percent_Identity=24.3801652892562, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1787789, Length=504, Percent_Identity=20.8333333333333, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1789138, Length=502, Percent_Identity=21.7131474103586, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786249, Length=556, Percent_Identity=22.4820143884892, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17535599, Length=456, Percent_Identity=23.4649122807018, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17864214, Length=465, Percent_Identity=23.010752688172, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24654573, Length=405, Percent_Identity=22.4691358024691, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21356607, Length=500, Percent_Identity=22.8, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLB_BACSU (P39211)

Other databases:

- EMBL:   U66480
- EMBL:   AL009126
- EMBL:   X02795
- PIR:   D69735
- RefSeq:   NP_389643.1
- ProteinModelPortal:   P39211
- SMR:   P39211
- EnsemblBacteria:   EBBACT00000000046
- GeneID:   939560
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU17610
- NMPDR:   fig|224308.1.peg.1765
- GenoList:   BSU17610
- GeneTree:   EBGT00050000001374
- HOGENOM:   HBG511469
- OMA:   IRNAILW
- PhylomeDB:   P39211
- ProtClustDB:   CLSK2301462
- BioCyc:   BSUB:BSU17610-MONOMER
- BRENDA:   2.7.1.17
- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000
- PANTHER:   PTHR10196
- TIGRFAMs:   TIGR01312

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N

EC number: =2.7.1.17

Molecular weight: Translated: 55418; Mature: 55418

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00933 FGGY_KINASES_1; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVIGIDLGTSAVKTILVNQNGKVCAETSKRYPLIQEKAGYSEQNPEDWVQQTIEALAE
CCEEEEECCCHHHEEEEEECCCCCEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
LVSISNVQAKDIDGISYSGQMHGLVLLDQDRQVLRNAILWNDTRTTPQCIRMTEKFGDHL
HHHHCCCCCCCCCCCEECCCEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LDITKNRVLEGFTLPKMLWVKEHEPELFKKTAVFLLPKDYVRFRMTGVIHTEYSDAAGTL
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHHEEEEECHHHHHEEEEEEEEECCCCCCCEE
LLHITRKEWSNDICNQIGISADICPPLVESHDCVGSLLPHVAAKTGLLEKTKVYAGGADN
EEEEEHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCHHHEEEECCCCC
ACGAIGAGILSSGKTLCSIGTSGVILSYEEEKERDFKGKVHFFNHGKKDSFYTMGVTLAA
CHHHHHHHHHHCCCEEEEECCCCEEEEECHHHCCCCCCEEEEEECCCCCCEEEEEEEEEC
GYSLDWFKRTFAPNESFEQLLQGVEAIPIGANGLLYTPYLVGERTPHADSSIRGSLIGMD
CCCHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCEECCEEECCCCCCCCCCCCCEEEECC
GAHNRKHFLRAIMEGITFSLHESIELFREAGKSVHTVVSIGGGAKNDTWLQMQADIFNTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEECCCCEE
VIKLENEQGPAMGAAMLAAFGSGWFESLEECAEQFIREAAAFYPKAQNVQKYKTLFDLYK
EEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
NIYTHTKDLNTALKSFRKN
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKYVIGIDLGTSAVKTILVNQNGKVCAETSKRYPLIQEKAGYSEQNPEDWVQQTIEALAE
CCEEEEECCCHHHEEEEEECCCCCEEECCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHH
LVSISNVQAKDIDGISYSGQMHGLVLLDQDRQVLRNAILWNDTRTTPQCIRMTEKFGDHL
HHHHCCCCCCCCCCCEECCCEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
LDITKNRVLEGFTLPKMLWVKEHEPELFKKTAVFLLPKDYVRFRMTGVIHTEYSDAAGTL
HHHHHHHHHCCCCCCCEEEEECCCHHHHHHHEEEEECHHHHHEEEEEEEEECCCCCCCEE
LLHITRKEWSNDICNQIGISADICPPLVESHDCVGSLLPHVAAKTGLLEKTKVYAGGADN
EEEEEHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHHHHCCCCHHHEEEECCCCC
ACGAIGAGILSSGKTLCSIGTSGVILSYEEEKERDFKGKVHFFNHGKKDSFYTMGVTLAA
CHHHHHHHHHHCCCEEEEECCCCEEEEECHHHCCCCCCEEEEEECCCCCCEEEEEEEEEC
GYSLDWFKRTFAPNESFEQLLQGVEAIPIGANGLLYTPYLVGERTPHADSSIRGSLIGMD
CCCHHHHHHHCCCCHHHHHHHHCCCEEECCCCCCEECCEEECCCCCCCCCCCCCEEEECC
GAHNRKHFLRAIMEGITFSLHESIELFREAGKSVHTVVSIGGGAKNDTWLQMQADIFNTR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEECCCCEE
VIKLENEQGPAMGAAMLAAFGSGWFESLEECAEQFIREAAAFYPKAQNVQKYKTLFDLYK
EEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
NIYTHTKDLNTALKSFRKN
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009