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The map label for this gene is pksA

Identifier: 16078770

GI number: 16078770

Start: 1781906

End: 1782523

Strand: Direct

Name: pksA

Synonym: BSU17080

Alternate gene names: 16078770

Gene position: 1781906-1782523 (Clockwise)

Preceding gene: 16078768

Following gene: 16078771

Centisome position: 42.27

GC content: 43.04

Gene sequence:

>618_bases
ATGCCAAAACAAATTGACCATGAGAAAAGAAGAAAACAAATTGCAGAAGCAACGTGGCGCGTCATTTTAGAACGAGGGAT
GGAGGGAGCATCAGCCAGAAATATTGCAAAGGAAGCAGGATTGTCATTAGGTGCGCTGCGCCATTATTTCTCTACACAGG
ATGAATTGCTTGCTTTTGCAATGAAACTTGTCCAAGAAAAGGTAACGGACCGAATTAAGGACATTGCAGTGAGGGATTTG
CTCCCTAAGGAAAAAGTGTTGCAAATTTTGCTTGAAATGGTCCCAACGAATGAAGAAACGATTAGAGAGATGGAGGTTTG
GTTTGCTTTTACTGCTTACGCCAGACATAAAAAGGATATGTTTGATGCGAGTCATGACGGGATTTTCAGCGGCATGCGGA
ATCTGATTGCCTATTTAGATGAATCCGATTTACTGAAGCAGAATGCTGATAAAGACATTGAAGCTGAGAGACTTTACGCG
CTTGTTGACGGCTTGGCTTTACATGCCATGCTTGACCCTGTGCGCGTGAATAAAGACCGAATCAAGCGGGTCATTATGCA
GCATGTAGAGTCAATTTGCGTGGAAGATACACGTGAGACACAAAAACGACATCCTTAA

Upstream 100 bases:

>100_bases
ACAGTTGTATTATTTAAATAATATGTTACCATCTTTGTTTTTGTAACACAACTGTATTATAAAAATTGCCCTCTCATTTT
TTTCTTGTTACAATAAAGCT

Downstream 100 bases:

>100_bases
GGCACTAGTGTGAAAAGCGATTCTTGTTGGGCATGCGTCCAAAAGAGTCGCTTTTTTATTTTCAAAGAACAAGGATCTCT
GAAAAAAATGGAAAACAATC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MPKQIDHEKRRKQIAEATWRVILERGMEGASARNIAKEAGLSLGALRHYFSTQDELLAFAMKLVQEKVTDRIKDIAVRDL
LPKEKVLQILLEMVPTNEETIREMEVWFAFTAYARHKKDMFDASHDGIFSGMRNLIAYLDESDLLKQNADKDIEAERLYA
LVDGLALHAMLDPVRVNKDRIKRVIMQHVESICVEDTRETQKRHP

Sequences:

>Translated_205_residues
MPKQIDHEKRRKQIAEATWRVILERGMEGASARNIAKEAGLSLGALRHYFSTQDELLAFAMKLVQEKVTDRIKDIAVRDL
LPKEKVLQILLEMVPTNEETIREMEVWFAFTAYARHKKDMFDASHDGIFSGMRNLIAYLDESDLLKQNADKDIEAERLYA
LVDGLALHAMLDPVRVNKDRIKRVIMQHVESICVEDTRETQKRHP
>Mature_204_residues
PKQIDHEKRRKQIAEATWRVILERGMEGASARNIAKEAGLSLGALRHYFSTQDELLAFAMKLVQEKVTDRIKDIAVRDLL
PKEKVLQILLEMVPTNEETIREMEVWFAFTAYARHKKDMFDASHDGIFSGMRNLIAYLDESDLLKQNADKDIEAERLYAL
VDGLALHAMLDPVRVNKDRIKRVIMQHVESICVEDTRETQKRHP

Specific function: Transcriptional regulation of the polyketide synthase operon

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1786505, Length=201, Percent_Identity=28.8557213930348, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PKSA_BACSU (O34381)

Other databases:

- EMBL:   AL009126
- PIR:   G69677
- RefSeq:   NP_389589.1
- ProteinModelPortal:   O34381
- SMR:   O34381
- EnsemblBacteria:   EBBACT00000000892
- GeneID:   939593
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU17080
- NMPDR:   fig|224308.1.peg.1710
- GenoList:   BSU17080
- GeneTree:   EBGT00050000000430
- HOGENOM:   HBG673138
- OMA:   GALRHYF
- PhylomeDB:   O34381
- ProtClustDB:   CLSK887321
- BioCyc:   BSUB:BSU17080-MONOMER
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- Gene3D:   G3DSA:1.10.357.10
- PRINTS:   PR00455

Pfam domain/function: PF00440 TetR_N; SSF46689 Homeodomain_like; SSF48498 TetR_like_C

EC number: NA

Molecular weight: Translated: 23741; Mature: 23610

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKQIDHEKRRKQIAEATWRVILERGMEGASARNIAKEAGLSLGALRHYFSTQDELLAFA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHH
MKLVQEKVTDRIKDIAVRDLLPKEKVLQILLEMVPTNEETIREMEVWFAFTAYARHKKDM
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FDASHDGIFSGMRNLIAYLDESDLLKQNADKDIEAERLYALVDGLALHAMLDPVRVNKDR
HCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IKRVIMQHVESICVEDTRETQKRHP
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PKQIDHEKRRKQIAEATWRVILERGMEGASARNIAKEAGLSLGALRHYFSTQDELLAFA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHH
MKLVQEKVTDRIKDIAVRDLLPKEKVLQILLEMVPTNEETIREMEVWFAFTAYARHKKDM
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FDASHDGIFSGMRNLIAYLDESDLLKQNADKDIEAERLYALVDGLALHAMLDPVRVNKDR
HCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IKRVIMQHVESICVEDTRETQKRHP
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377