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The map label for this gene is sdaAA

Identifier: 16078649

GI number: 16078649

Start: 1658930

End: 1659832

Strand: Direct

Name: sdaAA

Synonym: BSU15860

Alternate gene names: 16078649

Gene position: 1658930-1659832 (Clockwise)

Preceding gene: 16078648

Following gene: 16078650

Centisome position: 39.35

GC content: 47.4

Gene sequence:

>903_bases
ATGTTTCGTAATGTAAAAGAATTAATTGAGATTACTAAAGAAAAACAAATATTGATCTCTGATGTGATGATAGCTCAAGA
GATGGAAGTAACAGAAAAAACAAAAGAGGACATTTTTCAGCAGATGGATCATAACCTGTCTGTTATGGAAGCGGCGGTTC
AGAAAGGACTCGAGGGAGTTACGAGCCAAACGGGCTTAACAGGCGGAGATGCCGTTAAATTGCAGGCCTATATTCGATCA
GGAAAAAGCCTGTCTGGCCCGCTGATTTTAGATGCTGTATCGAAAGCCGTTGCAACAAATGAAGTAAATGCAGCCATGGG
AACCATCTGTGCGACACCGACTGCAGGTTCTGCCGGTGTGGTGCCCGGTACGTTATTTGCTGTAAAAGAAAAGCTGAATC
CAACAAGAGAACAAATGATCCGCTTTTTGTTTACAGCCGGGGCTTTCGGATTTGTCGTGGCCAATAACGCAAGCATTTCC
GGCGCCGCCGGAGGATGTCAGGCAGAGGTTGGATCAGCTTCAGGCATGGCGGCTGCGGCTATTGTTGAAATGGCAGGAGG
AACACCCGAACAAAGCGCGGAAGCCATGGCCATTACATTAAAAAATATGCTAGGCCTCGTGTGCGACCCTGTTGCAGGGC
TTGTTGAGGTGCCTTGCGTGAAACGGAATGCGATGGGCGCGTCAAATGCGATGATTGCTGCTGATATGGCATTGGCGGGC
ATTACAAGCCGTATTCCATGTGATGAGGTTATCGATGCCATGTATAAAATAGGCCAAACGATGCCAACTGCACTTAGAGA
AACAGGCCAGGGCGGTTTAGCGGCAACACCGACAGGAAGAGAATTAGAGAAAAAAATTTTCGGAGGAGCGCTAGGTTCAC
GTGAAACAACATCAGCAAACTAG

Upstream 100 bases:

>100_bases
AATATTGACGACCACATTCTCGACGAGCTGTCGAAGCTGCCGAATATTATTCAAGTGACAAAGATTGCTGACTAGCGAAA
AGGGTCAGGAGGAGCCAGTT

Downstream 100 bases:

>100_bases
TATAGCTAACATTAAGGGTATTGGGCCGGAAACAGAAAAAACATTGAATGAACTCGGTATTTATGACATTTCTGATCTTC
TGAATTATTTCCCTTATCGC

Product: L-serine dehydratase alpha chain

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MFRNVKELIEITKEKQILISDVMIAQEMEVTEKTKEDIFQQMDHNLSVMEAAVQKGLEGVTSQTGLTGGDAVKLQAYIRS
GKSLSGPLILDAVSKAVATNEVNAAMGTICATPTAGSAGVVPGTLFAVKEKLNPTREQMIRFLFTAGAFGFVVANNASIS
GAAGGCQAEVGSASGMAAAAIVEMAGGTPEQSAEAMAITLKNMLGLVCDPVAGLVEVPCVKRNAMGASNAMIAADMALAG
ITSRIPCDEVIDAMYKIGQTMPTALRETGQGGLAATPTGRELEKKIFGGALGSRETTSAN

Sequences:

>Translated_300_residues
MFRNVKELIEITKEKQILISDVMIAQEMEVTEKTKEDIFQQMDHNLSVMEAAVQKGLEGVTSQTGLTGGDAVKLQAYIRS
GKSLSGPLILDAVSKAVATNEVNAAMGTICATPTAGSAGVVPGTLFAVKEKLNPTREQMIRFLFTAGAFGFVVANNASIS
GAAGGCQAEVGSASGMAAAAIVEMAGGTPEQSAEAMAITLKNMLGLVCDPVAGLVEVPCVKRNAMGASNAMIAADMALAG
ITSRIPCDEVIDAMYKIGQTMPTALRETGQGGLAATPTGRELEKKIFGGALGSRETTSAN
>Mature_300_residues
MFRNVKELIEITKEKQILISDVMIAQEMEVTEKTKEDIFQQMDHNLSVMEAAVQKGLEGVTSQTGLTGGDAVKLQAYIRS
GKSLSGPLILDAVSKAVATNEVNAAMGTICATPTAGSAGVVPGTLFAVKEKLNPTREQMIRFLFTAGAFGFVVANNASIS
GAAGGCQAEVGSASGMAAAAIVEMAGGTPEQSAEAMAITLKNMLGLVCDPVAGLVEVPCVKRNAMGASNAMIAADMALAG
ITSRIPCDEVIDAMYKIGQTMPTALRETGQGGLAATPTGRELEKKIFGGALGSRETTSAN

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family

Homologues:

Organism=Escherichia coli, GI48994925, Length=281, Percent_Identity=37.0106761565836, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1788116, Length=282, Percent_Identity=38.6524822695035, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1789161, Length=283, Percent_Identity=37.1024734982332, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHA_BACSU (O34607)

Other databases:

- EMBL:   Y13937
- EMBL:   AL009126
- PIR:   G69879
- RefSeq:   NP_389468.1
- ProteinModelPortal:   O34607
- EnsemblBacteria:   EBBACT00000001964
- GeneID:   937109
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU15860
- NMPDR:   fig|224308.1.peg.1588
- GenoList:   BSU15860
- GeneTree:   EBGT00050000001424
- HOGENOM:   HBG304565
- OMA:   AMYKIGQ
- PhylomeDB:   O34607
- ProtClustDB:   CLSK887294
- BioCyc:   BSUB:BSU15860-MONOMER
- BRENDA:   4.3.1.17
- GO:   GO:0006094
- InterPro:   IPR005130
- InterPro:   IPR004642
- TIGRFAMs:   TIGR00718

Pfam domain/function: PF03313 SDH_alpha

EC number: =4.3.1.17

Molecular weight: Translated: 30936; Mature: 30936

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRNVKELIEITKEKQILISDVMIAQEMEVTEKTKEDIFQQMDHNLSVMEAAVQKGLEGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TSQTGLTGGDAVKLQAYIRSGKSLSGPLILDAVSKAVATNEVNAAMGTICATPTAGSAGV
HHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPGTLFAVKEKLNPTREQMIRFLFTAGAFGFVVANNASISGAAGGCQAEVGSASGMAAAA
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
IVEMAGGTPEQSAEAMAITLKNMLGLVCDPVAGLVEVPCVKRNAMGASNAMIAADMALAG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHH
ITSRIPCDEVIDAMYKIGQTMPTALRETGQGGLAATPTGRELEKKIFGGALGSRETTSAN
HHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFRNVKELIEITKEKQILISDVMIAQEMEVTEKTKEDIFQQMDHNLSVMEAAVQKGLEGV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TSQTGLTGGDAVKLQAYIRSGKSLSGPLILDAVSKAVATNEVNAAMGTICATPTAGSAGV
HHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VPGTLFAVKEKLNPTREQMIRFLFTAGAFGFVVANNASISGAAGGCQAEVGSASGMAAAA
CCHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
IVEMAGGTPEQSAEAMAITLKNMLGLVCDPVAGLVEVPCVKRNAMGASNAMIAADMALAG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHH
ITSRIPCDEVIDAMYKIGQTMPTALRETGQGGLAATPTGRELEKKIFGGALGSRETTSAN
HHCCCCHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377