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The map label for this gene is fruR

Identifier: 16078502

GI number: 16078502

Start: 1507578

End: 1508333

Strand: Direct

Name: fruR

Synonym: BSU14380

Alternate gene names: 16078502

Gene position: 1507578-1508333 (Clockwise)

Preceding gene: 16078501

Following gene: 16078503

Centisome position: 35.76

GC content: 41.53

Gene sequence:

>756_bases
ATGCTAACTCCTGAACGGCATCAATTGATTATTGATCAAATAGAAAAGCATGATGTGGTAAAGATTCAAGAGCTTATAAA
TCTGACTAATGCTTCTGAATCAACAATCAGAAGAGATTTATCGACCCTTGAAGAACGCGGTTTTTTAAAGCGCGTTCATG
GTGGAGCGGCCAAGCTTTCCGATATCAGACTTGAACCCGATATGCTTGAAAAATCATCCAAAAACCTTCACGATAAACTG
AAGATTGCTGAAAAAGCTGCTTCTCTTTTAGAAGAAGGGGATTGCATTTACCTTGATGCAGGCACGACGACATTGCACAT
GATTGATTTTATGGATAAAACCAAAGATATTGTCGTTGTCACAAACGGGGTAATGCATATCGATGCATTAATAAGGAAAG
AAATTTCTTTTTATCTGCTTGGAGGATACGTAAAGCACAGAACGGGCGCGATTATTGGAGGCGCTTCATTGGTTGCCATG
GACCAGTACAGATTTGACAAGAGTTTTCTGGGGACAAACGGTGTCCATACAGAGGCTGGATTTACAACGCCGGACCCTGA
TGAGGCCCTTTTAAAACAGAAAGCGATCAAACAGGCAAAACACGCTTACGTCTTAGCAGACCCTTCGAAGTTCGGAGAAA
TTTCATTTTCGGCATTCGCCGGAATAGGCGACGCAACAATCATTACGACTGACGCTGAAGAGCTTACATTCGATAATTAC
CAAGAAAAAACTGTCGTAAAGGTAGTGAAACCATGA

Upstream 100 bases:

>100_bases
TTATTGAATGAATTTGAATGATTTTAGTTGCCTAAACCGAAAATAGCGTTTACAATGAAATTGTATTCAAAATGAATACG
TTTTCATTAGGAGGTGAAGC

Downstream 100 bases:

>100_bases
TTTACACTGTAACACTTAATCCATCTGTCGATTATATAGTTCACGTTGAAGATTTTACTGTAGGAGGCCTGAACCGTTCT
TCGTATGATACCAAGTATCC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLTPERHQLIIDQIEKHDVVKIQELINLTNASESTIRRDLSTLEERGFLKRVHGGAAKLSDIRLEPDMLEKSSKNLHDKL
KIAEKAASLLEEGDCIYLDAGTTTLHMIDFMDKTKDIVVVTNGVMHIDALIRKEISFYLLGGYVKHRTGAIIGGASLVAM
DQYRFDKSFLGTNGVHTEAGFTTPDPDEALLKQKAIKQAKHAYVLADPSKFGEISFSAFAGIGDATIITTDAEELTFDNY
QEKTVVKVVKP

Sequences:

>Translated_251_residues
MLTPERHQLIIDQIEKHDVVKIQELINLTNASESTIRRDLSTLEERGFLKRVHGGAAKLSDIRLEPDMLEKSSKNLHDKL
KIAEKAASLLEEGDCIYLDAGTTTLHMIDFMDKTKDIVVVTNGVMHIDALIRKEISFYLLGGYVKHRTGAIIGGASLVAM
DQYRFDKSFLGTNGVHTEAGFTTPDPDEALLKQKAIKQAKHAYVLADPSKFGEISFSAFAGIGDATIITTDAEELTFDNY
QEKTVVKVVKP
>Mature_251_residues
MLTPERHQLIIDQIEKHDVVKIQELINLTNASESTIRRDLSTLEERGFLKRVHGGAAKLSDIRLEPDMLEKSSKNLHDKL
KIAEKAASLLEEGDCIYLDAGTTTLHMIDFMDKTKDIVVVTNGVMHIDALIRKEISFYLLGGYVKHRTGAIIGGASLVAM
DQYRFDKSFLGTNGVHTEAGFTTPDPDEALLKQKAIKQAKHAYVLADPSKFGEISFSAFAGIGDATIITTDAEELTFDNY
QEKTVVKVVKP

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1789519, Length=217, Percent_Identity=31.7972350230415, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI226510968, Length=216, Percent_Identity=30.0925925925926, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789059, Length=231, Percent_Identity=31.6017316017316, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789829, Length=233, Percent_Identity=30.0429184549356, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787540, Length=229, Percent_Identity=28.3842794759825, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788069, Length=243, Percent_Identity=26.7489711934156, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082344, Length=228, Percent_Identity=23.2456140350877, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790753, Length=235, Percent_Identity=22.9787234042553, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790635, Length=224, Percent_Identity=26.7857142857143, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1787063, Length=237, Percent_Identity=24.8945147679325, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=24.7863247863248, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRUR_BACSU (O31713)

Other databases:

- EMBL:   AF012285
- EMBL:   AL009126
- PIR:   B69627
- RefSeq:   NP_389321.1
- ProteinModelPortal:   O31713
- SMR:   O31713
- EnsemblBacteria:   EBBACT00000000937
- GeneID:   936082
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14380
- NMPDR:   fig|224308.1.peg.1440
- GenoList:   BSU14380
- GeneTree:   EBGT00050000001025
- HOGENOM:   HBG694151
- OMA:   KFGEISF
- PhylomeDB:   O31713
- ProtClustDB:   CLSK887232
- BioCyc:   BSUB:BSU14380-MONOMER
- GO:   GO:0005622
- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00037
- SMART:   SM00420

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR

EC number: NA

Molecular weight: Translated: 27817; Mature: 27817

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00894 HTH_DEOR_1; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPERHQLIIDQIEKHDVVKIQELINLTNASESTIRRDLSTLEERGFLKRVHGGAAKLS
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DIRLEPDMLEKSSKNLHDKLKIAEKAASLLEEGDCIYLDAGTTTLHMIDFMDKTKDIVVV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHHCCCCCEEEE
TNGVMHIDALIRKEISFYLLGGYVKHRTGAIIGGASLVAMDQYRFDKSFLGTNGVHTEAG
ECCHHHHHHHHHHHHHHEEECCHHHHCCCEEECCCCEEEEHHHHCCHHHCCCCCCCCCCC
FTTPDPDEALLKQKAIKQAKHAYVLADPSKFGEISFSAFAGIGDATIITTDAEELTFDNY
CCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCCEEHHHHCCCCCCEEEEECHHHHCCCCC
QEKTVVKVVKP
CCCEEEEEECC
>Mature Secondary Structure
MLTPERHQLIIDQIEKHDVVKIQELINLTNASESTIRRDLSTLEERGFLKRVHGGAAKLS
CCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DIRLEPDMLEKSSKNLHDKLKIAEKAASLLEEGDCIYLDAGTTTLHMIDFMDKTKDIVVV
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHHCCCCCEEEE
TNGVMHIDALIRKEISFYLLGGYVKHRTGAIIGGASLVAMDQYRFDKSFLGTNGVHTEAG
ECCHHHHHHHHHHHHHHEEECCHHHHCCCEEECCCCEEEEHHHHCCHHHCCCCCCCCCCC
FTTPDPDEALLKQKAIKQAKHAYVLADPSKFGEISFSAFAGIGDATIITTDAEELTFDNY
CCCCCHHHHHHHHHHHHHHHCEEEEECCCCCCCEEHHHHCCCCCCEEEEECHHHHCCCCC
QEKTVVKVVKP
CCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377