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The map label for this gene is fruK

Identifier: 16078503

GI number: 16078503

Start: 1508330

End: 1509241

Strand: Direct

Name: fruK

Synonym: BSU14390

Alternate gene names: 16078503

Gene position: 1508330-1509241 (Clockwise)

Preceding gene: 16078502

Following gene: 16078504

Centisome position: 35.78

GC content: 44.52

Gene sequence:

>912_bases
ATGATTTACACTGTAACACTTAATCCATCTGTCGATTATATAGTTCACGTTGAAGATTTTACTGTAGGAGGCCTGAACCG
TTCTTCGTATGATACCAAGTATCCAGGGGGCAAAGGCATCAACGTATCGAGACTGCTGAAAAGACACCATGTGGCGTCTA
AAGCGCTCGGATTCGTCGGCGGATTTACCGGAGAATATATCAAAACATTTTTACGGGAAGAAAACCTGGAAACAGCTTTT
TCTGAAGTAAAAGGGGATACCCGTATCAATGTAAAGCTGAAAACGGGTGATGAAACTGAAATTAACGGGCAGGGACCGAC
AATTTCGGATGAAGATTTCAAAGCCTTTTTAGAACAGTTCCAATCTTTGCAAGAGGGAGATATCGTTGTTCTTGCAGGAA
GCATTCCATCTTCACTCCCTCACGATACTTATGAAAAAATCGCAGAGGCCTGCAAACAGCAGAACGCACGAGTTGTTCTG
GATATCTCAGGCGAGGCTCTTTTGAAAGCAACAGAAATGAAACCATTTTTGATGAAGCCAAATCATCATGAGCTTGGAGA
AATGTTCGGCACGGCCATTACATCTGTTGAGGAAGCCGTTCCTTATGGGAAAAAGCTTGTAGAACAAGGCGCTGAACATG
TAATCGTATCAATGGCCGGAGACGGAGCGCTTCTGTTTACGAACGAAGCTGTTTATTTTGCTAACGTGCCAAAGGGGAAA
TTGGTAAACTCAGTCGGAGCAGGGGATTCCGTTGTTGCAGGTTTCCTTGCCGGAATTTCCAAACAGCTGCCGCTTGAAGA
AGCATTCCGCTTAGGAGTTACTTCAGGCAGTGCTACCGCGTTCTCTGAAGAACTTGGAACAGAAGAATTTGTCCAGCAGC
TTCTTCCTGAAGTTAAGGTCACACGTCTATAG

Upstream 100 bases:

>100_bases
CATTCGCCGGAATAGGCGACGCAACAATCATTACGACTGACGCTGAAGAGCTTACATTCGATAATTACCAAGAAAAAACT
GTCGTAAAGGTAGTGAAACC

Downstream 100 bases:

>100_bases
AGGAGGAAACACAAGTGAAAATAACTGAGCTTTTAACGAAGCATACGATAAAGCTTAATATTGAGAGCAAAGAAAAAGAA
AATGTTATTGACGAAATGGT

Product: fructose-1-phosphate kinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MIYTVTLNPSVDYIVHVEDFTVGGLNRSSYDTKYPGGKGINVSRLLKRHHVASKALGFVGGFTGEYIKTFLREENLETAF
SEVKGDTRINVKLKTGDETEINGQGPTISDEDFKAFLEQFQSLQEGDIVVLAGSIPSSLPHDTYEKIAEACKQQNARVVL
DISGEALLKATEMKPFLMKPNHHELGEMFGTAITSVEEAVPYGKKLVEQGAEHVIVSMAGDGALLFTNEAVYFANVPKGK
LVNSVGAGDSVVAGFLAGISKQLPLEEAFRLGVTSGSATAFSEELGTEEFVQQLLPEVKVTRL

Sequences:

>Translated_303_residues
MIYTVTLNPSVDYIVHVEDFTVGGLNRSSYDTKYPGGKGINVSRLLKRHHVASKALGFVGGFTGEYIKTFLREENLETAF
SEVKGDTRINVKLKTGDETEINGQGPTISDEDFKAFLEQFQSLQEGDIVVLAGSIPSSLPHDTYEKIAEACKQQNARVVL
DISGEALLKATEMKPFLMKPNHHELGEMFGTAITSVEEAVPYGKKLVEQGAEHVIVSMAGDGALLFTNEAVYFANVPKGK
LVNSVGAGDSVVAGFLAGISKQLPLEEAFRLGVTSGSATAFSEELGTEEFVQQLLPEVKVTRL
>Mature_303_residues
MIYTVTLNPSVDYIVHVEDFTVGGLNRSSYDTKYPGGKGINVSRLLKRHHVASKALGFVGGFTGEYIKTFLREENLETAF
SEVKGDTRINVKLKTGDETEINGQGPTISDEDFKAFLEQFQSLQEGDIVVLAGSIPSSLPHDTYEKIAEACKQQNARVVL
DISGEALLKATEMKPFLMKPNHHELGEMFGTAITSVEEAVPYGKKLVEQGAEHVIVSMAGDGALLFTNEAVYFANVPKGK
LVNSVGAGDSVVAGFLAGISKQLPLEEAFRLGVTSGSATAFSEELGTEEFVQQLLPEVKVTRL

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family

Homologues:

Organism=Escherichia coli, GI1788493, Length=272, Percent_Identity=30.1470588235294, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1788017, Length=287, Percent_Identity=31.0104529616725, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): K1PF_BACSU (O31714)

Other databases:

- EMBL:   AF012285
- EMBL:   AL009126
- PIR:   A69627
- RefSeq:   NP_389322.1
- ProteinModelPortal:   O31714
- SMR:   O31714
- EnsemblBacteria:   EBBACT00000000609
- GeneID:   938761
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU14390
- NMPDR:   fig|224308.1.peg.1441
- GenoList:   BSU14390
- GeneTree:   EBGT00050000001878
- HOGENOM:   HBG670529
- OMA:   GIDNTAT
- PhylomeDB:   O31714
- ProtClustDB:   CLSK887233
- BioCyc:   BSUB:BSU14390-MONOMER
- BRENDA:   2.7.1.56
- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583
- TIGRFAMs:   TIGR03168
- TIGRFAMs:   TIGR03828

Pfam domain/function: PF00294 PfkB

EC number: =2.7.1.56

Molecular weight: Translated: 32792; Mature: 32792

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00583 PFKB_KINASES_1; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTVTLNPSVDYIVHVEDFTVGGLNRSSYDTKYPGGKGINVSRLLKRHHVASKALGFVG
CEEEEEECCCCCEEEEEECEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GFTGEYIKTFLREENLETAFSEVKGDTRINVKLKTGDETEINGQGPTISDEDFKAFLEQF
CCCHHHHHHHHHHCCHHHHHHHHCCCEEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHH
QSLQEGDIVVLAGSIPSSLPHDTYEKIAEACKQQNARVVLDISGEALLKATEMKPFLMKP
HCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCEEECC
NHHELGEMFGTAITSVEEAVPYGKKLVEQGAEHVIVSMAGDGALLFTNEAVYFANVPKGK
CHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCEEEEECCEEEEEECCCCH
LVNSVGAGDSVVAGFLAGISKQLPLEEAFRLGVTSGSATAFSEELGTEEFVQQLLPEVKV
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHCHHEE
TRL
CCC
>Mature Secondary Structure
MIYTVTLNPSVDYIVHVEDFTVGGLNRSSYDTKYPGGKGINVSRLLKRHHVASKALGFVG
CEEEEEECCCCCEEEEEECEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GFTGEYIKTFLREENLETAFSEVKGDTRINVKLKTGDETEINGQGPTISDEDFKAFLEQF
CCCHHHHHHHHHHCCHHHHHHHHCCCEEEEEEEECCCCCEECCCCCCCCCHHHHHHHHHH
QSLQEGDIVVLAGSIPSSLPHDTYEKIAEACKQQNARVVLDISGEALLKATEMKPFLMKP
HCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCEEECC
NHHELGEMFGTAITSVEEAVPYGKKLVEQGAEHVIVSMAGDGALLFTNEAVYFANVPKGK
CHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCEEEEECCEEEEEECCCCH
LVNSVGAGDSVVAGFLAGISKQLPLEEAFRLGVTSGSATAFSEELGTEEFVQQLLPEVKV
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHCHHEE
TRL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377