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The map label for this gene is ykvY

Identifier: 16078450

GI number: 16078450

Start: 1453691

End: 1454782

Strand: Direct

Name: ykvY

Synonym: BSU13860

Alternate gene names: 16078450

Gene position: 1453691-1454782 (Clockwise)

Preceding gene: 16078449

Following gene: 16078451

Centisome position: 34.48

GC content: 45.6

Gene sequence:

>1092_bases
GTGAATAGAATACAACGCGTCTCTTCATGGCTGAAGGAAGCGGGGCATACTGCCGCATTTATTCATACGAAAGAAAATGT
TTTTTACTTAACCGGTTTTTACACAGAGCCGCATGAAAGATTAATGGGGTTATTTATTTTTCAAGAAGAGGAGCCTTTCT
TTGTTTGTCCAGGAATGGAAGCAGGACAGGCCCGCAACGCAGGCTGGAATCATGAAATCATTGGCTATGCGGATCACGAA
AATCCGTGGGAGCTGATAGAGAAGGCTTTGAAAAAGCGAAATATCAGCATACATATGCTTGCGGTAGAAAAGGATTCAAT
CTCGCTGTCACGTGCAGAACAGCTGAAGCATGCGACGGGCGGGGCTCAATTTGTTTCAGCAGAAGAAACACTCAATCAAT
TTCGCCTGATTAAAGATGACAATGAGATTCGTTTGCTGAAAGAGGCGGCAAAGCTTGCAGATTACGGTGTTGAAGTCGGC
ACAGCCGCTTTGCGTGAAGGCATCAGTGAAGTGGAAGTGCTCGCTCAAATTGAGTATGAGCTGAAGAAAAAAGGAATTCA
GGGCATGTCTTTCTCTACAATGGTTTTATTCGGAGAAAAATCTGGCCAGCCTCATGGAAATCCTGGTACAGCCACGTTGA
AGAAAGGTGATTTTGTTTTATTTGATCTCGGTGTTATTCTTGATGGCTATTGCTCTGATATTACAAGAACGTTTGCATAC
AAAACCATCAATCCGAAGCAGGAGGCCATTTACGAGACTGTGCTTCAAGCGGAAAAAGCCGCGATTGAGGCAAGCAAACC
CGGTGTGAGAATCGGAGATCTGGATTTAACTGCCCGCGGAATCATTGAAAAAGCGGGATATGGTGATTATTTTCCTCACC
GGCTTGGGCATGGACTCGGAATTTCAGTCCATGAGTATCCATCAATGAGCCAGGCCAACGATACACTGCTGCAGGAAGGC
ATGGTCTACACGATCGAACCGGGGATTTATGTGCCAGAGATCGGCGGCGTACGCATTGAGGATGACGTTCACGTAACAAA
GGACGGAGCAGTTGCTCTGACCCAATATCCAAAGGATTTGATCATACTGTAA

Upstream 100 bases:

>100_bases
TGCATTAGAAAATGAAGGCGTCGTGAAAGGCAAACACCGGTAAAACCTGTTACAATGGAAGACAGAACAATGCATTGCAA
ATGGCAGGGAGGAACAAGAA

Downstream 100 bases:

>100_bases
TAGAAATAAAAAAGGACTTTGTTCTCGACATCGTCCTTTTTTATCTGCATTAAATAAAAAAATCATCAAATGTTCGAAAG
GGTTTAATTTCATGTTTTTG

Product: Xaa-Pro dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNRIQRVSSWLKEAGHTAAFIHTKENVFYLTGFYTEPHERLMGLFIFQEEEPFFVCPGMEAGQARNAGWNHEIIGYADHE
NPWELIEKALKKRNISIHMLAVEKDSISLSRAEQLKHATGGAQFVSAEETLNQFRLIKDDNEIRLLKEAAKLADYGVEVG
TAALREGISEVEVLAQIEYELKKKGIQGMSFSTMVLFGEKSGQPHGNPGTATLKKGDFVLFDLGVILDGYCSDITRTFAY
KTINPKQEAIYETVLQAEKAAIEASKPGVRIGDLDLTARGIIEKAGYGDYFPHRLGHGLGISVHEYPSMSQANDTLLQEG
MVYTIEPGIYVPEIGGVRIEDDVHVTKDGAVALTQYPKDLIIL

Sequences:

>Translated_363_residues
MNRIQRVSSWLKEAGHTAAFIHTKENVFYLTGFYTEPHERLMGLFIFQEEEPFFVCPGMEAGQARNAGWNHEIIGYADHE
NPWELIEKALKKRNISIHMLAVEKDSISLSRAEQLKHATGGAQFVSAEETLNQFRLIKDDNEIRLLKEAAKLADYGVEVG
TAALREGISEVEVLAQIEYELKKKGIQGMSFSTMVLFGEKSGQPHGNPGTATLKKGDFVLFDLGVILDGYCSDITRTFAY
KTINPKQEAIYETVLQAEKAAIEASKPGVRIGDLDLTARGIIEKAGYGDYFPHRLGHGLGISVHEYPSMSQANDTLLQEG
MVYTIEPGIYVPEIGGVRIEDDVHVTKDGAVALTQYPKDLIIL
>Mature_363_residues
MNRIQRVSSWLKEAGHTAAFIHTKENVFYLTGFYTEPHERLMGLFIFQEEEPFFVCPGMEAGQARNAGWNHEIIGYADHE
NPWELIEKALKKRNISIHMLAVEKDSISLSRAEQLKHATGGAQFVSAEETLNQFRLIKDDNEIRLLKEAAKLADYGVEVG
TAALREGISEVEVLAQIEYELKKKGIQGMSFSTMVLFGEKSGQPHGNPGTATLKKGDFVLFDLGVILDGYCSDITRTFAY
KTINPKQEAIYETVLQAEKAAIEASKPGVRIGDLDLTARGIIEKAGYGDYFPHRLGHGLGISVHEYPSMSQANDTLLQEG
MVYTIEPGIYVPEIGGVRIEDDVHVTKDGAVALTQYPKDLIIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family

Homologues:

Organism=Homo sapiens, GI11559925, Length=262, Percent_Identity=30.5343511450382, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI149589008, Length=337, Percent_Identity=29.3768545994065, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI260593665, Length=337, Percent_Identity=29.3768545994065, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI260593663, Length=268, Percent_Identity=31.7164179104478, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=25.4032258064516, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1788728, Length=246, Percent_Identity=42.2764227642276, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1789275, Length=283, Percent_Identity=28.9752650176678, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790282, Length=291, Percent_Identity=26.4604810996564, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17508215, Length=292, Percent_Identity=26.3698630136986, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71989583, Length=277, Percent_Identity=26.3537906137184, Blast_Score=84, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6321118, Length=283, Percent_Identity=28.6219081272085, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320922, Length=246, Percent_Identity=27.2357723577236, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI19920384, Length=308, Percent_Identity=27.9220779220779, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21357079, Length=293, Percent_Identity=29.3515358361775, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YKVY_BACSU (O31689)

Other databases:

- EMBL:   AL009126
- PIR:   G69869
- RefSeq:   NP_389269.1
- HSSP:   P81535
- ProteinModelPortal:   O31689
- SMR:   O31689
- MEROPS:   M24.006
- EnsemblBacteria:   EBBACT00000003734
- GeneID:   939258
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU13860
- NMPDR:   fig|224308.1.peg.1388
- GenoList:   BSU13860
- GeneTree:   EBGT00070000031884
- HOGENOM:   HBG545079
- OMA:   ENRSELE
- PhylomeDB:   O31689
- ProtClustDB:   CLSK887205
- BioCyc:   BSUB:BSU13860-MONOMER
- GO:   GO:0006508
- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131
- Gene3D:   G3DSA:3.90.230.10
- PANTHER:   PTHR10804
- PRINTS:   PR00599

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24; SSF55920 Peptidase_M24_cat_core

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40334; Mature: 40334

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIQRVSSWLKEAGHTAAFIHTKENVFYLTGFYTEPHERLMGLFIFQEEEPFFVCPGME
CCHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCHHHHHEEEEEEECCCCEEEECCCC
AGQARNAGWNHEIIGYADHENPWELIEKALKKRNISIHMLAVEKDSISLSRAEQLKHATG
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCC
GAQFVSAEETLNQFRLIKDDNEIRLLKEAAKLADYGVEVGTAALREGISEVEVLAQIEYE
CCEEEEHHHHHHHEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHH
LKKKGIQGMSFSTMVLFGEKSGQPHGNPGTATLKKGDFVLFDLGVILDGYCSDITRTFAY
HHHCCCCCCCEEEEEEEECCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHE
KTINPKQEAIYETVLQAEKAAIEASKPGVRIGDLDLTARGIIEKAGYGDYFPHRLGHGLG
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHCCCCCCCHHHHCCCCC
ISVHEYPSMSQANDTLLQEGMVYTIEPGIYVPEIGGVRIEDDVHVTKDGAVALTQYPKDL
CEEECCCCCCCCCHHHHHCCCEEEECCCEEECCCCCEEEECCEEEECCCCEEEECCCCCE
IIL
EEC
>Mature Secondary Structure
MNRIQRVSSWLKEAGHTAAFIHTKENVFYLTGFYTEPHERLMGLFIFQEEEPFFVCPGME
CCHHHHHHHHHHHCCCEEEEEEECCCEEEEEEECCCHHHHHEEEEEEECCCCEEEECCCC
AGQARNAGWNHEIIGYADHENPWELIEKALKKRNISIHMLAVEKDSISLSRAEQLKHATG
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCC
GAQFVSAEETLNQFRLIKDDNEIRLLKEAAKLADYGVEVGTAALREGISEVEVLAQIEYE
CCEEEEHHHHHHHEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHH
LKKKGIQGMSFSTMVLFGEKSGQPHGNPGTATLKKGDFVLFDLGVILDGYCSDITRTFAY
HHHCCCCCCCEEEEEEEECCCCCCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHHE
KTINPKQEAIYETVLQAEKAAIEASKPGVRIGDLDLTARGIIEKAGYGDYFPHRLGHGLG
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHCCCCCCCHHHHCCCCC
ISVHEYPSMSQANDTLLQEGMVYTIEPGIYVPEIGGVRIEDDVHVTKDGAVALTQYPKDL
CEEECCCCCCCCCHHHHHCCCEEEECCCEEECCCCCEEEECCEEEECCCCEEEECCCCCE
IIL
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377